20042019

Research output per year

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Research Output

2019

Azathioprine Biotransformation in Young Patients with Inflammatory Bowel Disease: Contribution of Glutathione-S Transferase M1 and A1 Variants

Lucafò, M., Stocco, G., Martelossi, S., Favretto, D., Franca, R., Malusà, N., Lora, A., Bramuzzo, M., Naviglio, S., Cecchin, E., Toffoli, G., Ventura, A. & Decorti, G., Apr 2019, In : Genes. 10, 4, 12 p., 277.

Research output: Contribution to journalArticle

Open Access
Open Access

Emerging Insights on the Interaction Between Anticancer and Immunosuppressant Drugs and Intestinal Microbiota in Pediatric Patients

Lucafò, M., Franzin, M., Lagatolla, C., Franca, R., Bramuzzo, M., Stocco, G. & Decorti, G., Jan 1 2019, (Accepted/In press) In : Clinical and Translational Science.

Research output: Contribution to journalReview article

Open Access

MIF plasma level as a possible tool to predict steroid responsiveness in children with idiopathic nephrotic syndrome

Cuzzoni, E., Franca, R., De Iudicibus, S., Marcuzzi, A., Lucafò, M., Pelin, M., Favretto, D., Monti, E., Morello, W., Ghio, L., La Scola, C., Mencarelli, F., Pasini, A., Montini, G., Decorti, G. & Stocco, G., Dec 2019, In : European Journal of Clinical Pharmacology. 75, 12, p. 1675-1683 9 p.

Research output: Contribution to journalArticle

MIF plasma level as a possible tool to predict steroid responsiveness in children with idiopathic nephrotic syndrome

Cuzzoni, E., Franca, R., De Iudicibus, S., Marcuzzi, A., Lucafò, M., Pelin, M., Favretto, D., Monti, E., Morello, W., Ghio, L., La Scola, C., Mencarelli, F., Pasini, A., Montini, G., Decorti, G. & Stocco, G., 2019, In : European Journal of Clinical Pharmacology. 75, 12, p. 1675-1683

Research output: Contribution to journalArticle

PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients

Franca, R., Stocco, G., Favretto, D., Giurici, N., del Rizzo, I., Locatelli, F., Vinti, L., Biondi, A., Colombini, A., Fagioli, F., Barisone, E., Pelin, M., Martellossi, S., Ventura, A., Decorti, G. & Rabusin, M., Jan 1 2019, (Accepted/In press) In : Pharmacogenomics Journal.

Research output: Contribution to journalArticle

PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients

Franca, R., Stocco, G., Favretto, D., Giurici, N., del Rizzo, I., Locatelli, F., Vinti, L., Biondi, A., Colombini, A., Fagioli, F., Barisone, E., Pelin, M., Martellossi, S., Ventura, A., Decorti, G. & Rabusin, M., Jan 1 2019, In : Pharmacogenomics Journal.

Research output: Contribution to journalArticle

2018

Pharmacogenetics of treatments for inflammatory bowel disease

Lucafò, M., Franca, R., Selvestrel, D., Curci, D., Pugnetti, L., Decorti, G. & Stocco, G., Dec 2018, In : Expert opinion on drug metabolism & toxicology. 14, 12, p. 1209-1223 15 p.

Research output: Contribution to journalReview article

Pharmacogenetics of treatments for inflammatory bowel disease

Lucafò, M., Franca, R., Selvestrel, D., Curci, D., Pugnetti, L., Decorti, G. & Stocco, G., Dec 2 2018, In : Expert Opinion on Drug Metabolism and Toxicology. 14, 12, p. 1209-1223 15 p.

Research output: Contribution to journalReview article

2017

Epratuzumab and blinatumomab as therapeutic antibodies for treatment of pediatric acute lymphoblastic leukemia: Current status and future perspectives

Franca, R., Favretto, D., Granzotto, M., Decorti, G., Rabusin, M. & Stocco, G., Apr 1 2017, In : Current Medicinal Chemistry. 24, 11, p. 1050-1065 16 p.

Research output: Contribution to journalReview article

Multicentric Case-Control Study on Azathioprine Dose and Pharmacokinetics in Early-onset Pediatric Inflammatory Bowel Disease

Stocco, G., Martelossi, S., Arrigo, S., Barabino, A., Aloi, M., Martinelli, M., Miele, E., Knafelz, D., Romano, C., Naviglio, S., Favretto, D., Cuzzoni, E., Franca, R., Decorti, G. & Ventura, A., 2017, In : Inflammatory Bowel Diseases. 23, 4, p. 628-634 7 p.

Research output: Contribution to journalArticle

Multicentric Case-Control Study on Azathioprine Dose and Pharmacokinetics in Early-onset Pediatric Inflammatory Bowel Disease

Stocco, G., Martelossi, S., Arrigo, S., Barabino, A., Aloi, M., Martinelli, M., Miele, E., Knafelz, D., Romano, C., Naviglio, S., Favretto, D., Cuzzoni, E., Franca, R., Decorti, G. & Ventura, A., Apr 1 2017, In : Inflammatory Bowel Diseases. 23, 4, p. 628-634 7 p.

Research output: Contribution to journalArticle

Pharmacogenetics and induction/consolidation therapy toxicities in acute lymphoblastic leukemia patients treated with AIEOP-BFM ALL 2000 protocol

Franca, R., Rebora, P., Bertorello, N., Fagioli, F., Conter, V., Biondi, A., Colombini, A., Micalizzi, C., Zecca, M., Parasole, R., Petruzziello, F., Basso, G., Putti, M. C., Locatelli, F., d'Adamo, P., Valsecchi, M. G., Decorti, G. & Rabusin, M., Jan 1 2017, In : Pharmacogenomics Journal. 17, 1, p. 4-10 7 p.

Research output: Contribution to journalArticle

Pharmacogenetics and induction/consolidation therapy toxicities in acute lymphoblastic leukemia patients treated with AIEOP-BFM ALL 2000 protocol

Franca, R., Rebora, P., Bertorello, N., Fagioli, F., Conter, V., Biondi, A., Colombini, A., Micalizzi, C., Zecca, M., Parasole, R., Petruzziello, F., Basso, G., Putti, M. C., Locatelli, N., d'Adamo, P., Valsecchi, M. G., Decorti, G. & Rabusin, M., Jan 2017, In : Pharmacogenomics Journal. 17, 1, p. 4-10 7 p.

Research output: Contribution to journalArticle

Targeting kinase-activating genetic lesions to improve therapy of pediatric acute lymphoblastic leukemia

Kuzelicki, N. K., Sorio, C., Toffoletti, E., Montecchini, O., Poropat, A., Rabusin, M., Curci, D., Paladin, D., Stocco, G., Decorti, G. & Franca, R., Jul 27 2017, In : Current Medicinal Chemistry.

Research output: Contribution to journalArticle

2015

Contribution of glutathione-s-transferases to the pharmacogenetics of azathioprine

Stocco, G., Pelin, M., Franca, R., Iudicibus, S. D., Cuzzoni, E., Favretto, D., Candussio, L., Martelossi, S., Ventura, A. & Decorti, G., Jan 1 2015, Glutathione: Dietary Sources, Role in Cellular Functions and Therapeutic Effects. Nova Science Publishers, Inc., p. 69-84 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Glucocorticoid pharmacogenetics in pediatric idiopathic nephrotic syndrome

Cuzzoni, E., De Iudicibus, S., Franca, R., Stocco, G., Lucafò, M., Pelin, M., Favretto, D., Pasini, A., Montini, G. & Decorti, G., Sep 1 2015, In : Pharmacogenomics. 16, 14, p. 1631-1648 18 p.

Research output: Contribution to journalArticle

Pharmacogenetics and induction/consolidation therapy toxicities in acute lymphoblastic leukemia patients treated with AIEOP-BFM ALL 2000 protocol

Franca, R., Rebora, P., Bertorello, N., Fagioli, F., Conter, V., Biondi, A., Colombini, A., Micalizzi, C., Zecca, M., Parasole, R., Petruzziello, F., Basso, G., Putti, M. C., Locatelli, F., d'Adamo, P., Valsecchi, M. G., Decorti, G. & Rabusin, M., Dec 8 2015, (Accepted/In press) In : Pharmacogenomics Journal.

Research output: Contribution to journalArticle

Role of pharmacogenetics in hematopoietic stem cell transplantation outcome in children

Franca, R., Stocco, G., Favretto, D., Giurici, N., Decorti, G. & Rabusin, M., Aug 14 2015, In : International Journal of Molecular Sciences. 16, 8, p. 18601-18627 27 p.

Research output: Contribution to journalArticle

2014

Deletion of glutathione-S-transferase M1 reduces azathioprine metabolite concentrations in young patients with inflammatory bowel disease

Stocco, G., Cuzzoni, E., De Iudicibus, S., Franca, R., Favretto, D., Malusà, N., Londero, M., Cont, G., Bartoli, F., Martelossi, S., Ventura, A. & Decorti, G., Jan 2014, In : Journal of Clinical Gastroenterology. 48, 1, p. 43-51 9 p.

Research output: Contribution to journalArticle

Pharmacogenetics of azathioprine in inflammatory bowel disease: A role for glutathione-S-transferase?

Stocco, G., Pelin, M., Franca, R., De Iudicibus, S., Cuzzoni, E., Favretto, D., Martelossi, S., Ventura, A. & Decorti, G., Apr 7 2014, In : World Journal of Gastroenterology. 20, 13, p. 3534-3541 8 p.

Research output: Contribution to journalArticle

TNF-α SNP rs1800629 and risk of relapse in childhood acute lymphoblastic leukemia: Relation to immunophenotype

Franca, R., Rebora, P., Athanasakis, E., Favretto, D., Verzegnassi, F., Basso, G., Tommasini, A., Valsecchi, M. G., Decorti, G. & Rabusin, M., 2014, In : Pharmacogenomics. 15, 5, p. 619-627 9 p.

Research output: Contribution to journalArticle

2013

Pharmacogenomic approaches for tailored anti-leukemic therapy in children

Stocco, G., Franca, R., Verzegnassi, F., Londero, M., Rabusin, M. & Decorti, G., Jun 2013, In : Current Medicinal Chemistry. 20, 17, p. 2237-2253 17 p.

Research output: Contribution to journalArticle

Research highlights: Highlights from the latest articles in acute lymphoblastic leukemia pharmacogenomics

Stocco, G., Franca, R., Londero, M. & Decorti, G., Feb 2013, In : Pharmacogenomics. 14, 3, p. 235-236 2 p.

Research output: Contribution to journalArticle

2012

Glutathione S-transferase homozygous deletions and relapse in childhood acute lymphoblastic leukemia: A novel study design in a large Italian AIEOP cohort

Franca, R., Rebora, P., Basso, G., Biondi, A., Cazzaniga, G., Crovella, S., Decorti, G., Fagioli, F., Giarin, E., Locatelli, F., Poggi, V., Valsecchi, M. G. & Rabusin, M., Dec 2012, In : Pharmacogenomics. 13, 16, p. 1905-1916 12 p.

Research output: Contribution to journalArticle

PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity

Stocco, G., Yang, W., Crews, K. R., Thierfelder, W. E., Decorti, G., Londero, M., Franca, R., Rabusin, M., Valsecchi, M. G., Pei, D., Cheng, C., Paugh, S. W., Ramsey, L. B., Diouf, B., Mccorkle, J. R., Jones, T. S., Pui, C. H., Relling, M. V. & Evans, W. E., Nov 2012, In : Human Molecular Genetics. 21, 21, p. 4793-4804 12 p., dds302.

Research output: Contribution to journalArticle

Personalized therapies in pediatric inflammatory and autoimmune diseases

Stocco, G., de Iudicibus, S., Franca, R., Addobbati, R. & Decorti, G., 2012, In : Current Pharmaceutical Design. 18, 35, p. 5766-5775 10 p.

Research output: Contribution to journalArticle

2011

Identification and Functional Characterization of Bilitranslocase in Sea-Bass (Dicentrarchus labrax) Hepatopancreas

Delneri, A., Franca, R., Terdoslavich, M., Montanič, S., Čurin Šerbec, V., Tramer, F., Francese, M. & Passamonti, S., Dec 2011, In : Analytical Letters. 44, 18, p. 2887-2900 14 p.

Research output: Contribution to journalArticle

Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease

de Iudicibus, S., Franca, R., Martelossi, S., Ventura, A. & Decorti, G., Mar 7 2011, In : World Journal of Gastroenterology. 17, 9, p. 1095-1108 14 p.

Research output: Contribution to journalArticle

2010

Expression of kidney and liver bilitranslocase in response to acute biliary obstruction

Brandoni, A., Di Giusto, G., Franca, R., Passamonti, S. & Torres, A. M., Apr 2010, In : Nephron - Physiology. 114, 4

Research output: Contribution to journalArticle

The ectopic FOF1 ATP synthase of rat liver is modulated in acute cholestasis by the inhibitor protein IF1

Giorgio, V., Bisetto, E., Franca, R., Harris, D. A., Passamonti, S. & Lippe, G., Apr 2010, In : Journal of Bioenergetics and Biomembranes. 42, 2, p. 117-123 7 p.

Research output: Contribution to journalArticle

2009

Bioavailability of flavonoids: A review of their membrane transport and the function of bilitranslocase in animal and plant organisms

Passamonti, S., Terdoslavich, M., Franca, R., Vanzo, A., Tramer, F., Braidot, E., Petrussa, E. & Vianello, A., 2009, In : Current Drug Metabolism. 10, 4, p. 369-394 26 p.

Research output: Contribution to journalArticle

2007

Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity

Franca, R., Belfiore, A., Spadari, S. & Maga, G., Jun 2007, In : Proteins: Structure, Function and Genetics. 67, 4, p. 1128-1137 10 p.

Research output: Contribution to journalArticle

2006

APOBEC deaminases as cellular antiviral factors: A novel natural host defense mechanism

Franca, R., Spadari, S. & Maga, G., May 1 2006, In : Medical Science Monitor. 12, 5

Research output: Contribution to journalArticle

2005

Heterodimeric amino acid transporter glycoprotein domains determining functional subunit association

Franca, R., Veljkovic, E., Walter, S., Wagner, C. A. & Verrey, F., Jun 1 2005, In : Biochemical Journal. 388, 2, p. 435-443 9 p.

Research output: Contribution to journalArticle

2004

SPECT and PET amino acid tracer influx via system L (h4F2hc-hLAT1) and its transstimulation

Lahoutte, T., Caveliers, V., Camargo, S. M. R., Franca, R., Ramadan, T., Veljkovic, E., Mertens, J., Bossuyt, A. & Verrey, F., Sep 1 2004, In : Journal of Nuclear Medicine. 45, 9, p. 1591-1596 6 p.

Research output: Contribution to journalArticle