1988 …2020

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2020

Lack of Gut Secretory Immunoglobulin A in Memory B-Cell Dysfunction-Associated Disorders: A Possible Gut-Spleen Axis

Carsetti, R., Di Sabatino, A., Rosado, M. M., Cascioli, S., Piano Mortari, E., Milito, C., Grimsholm, O., Aranburu, A., Giorda, E., Tinozzi, F. P., Pulvirenti, F., Donato, G., Morini, F., Bagolan, P., Corazza, G. R. & Quinti, I., Jan 8 2020, In : Frontiers in Immunology. 10, 2937.

Research output: Contribution to journalArticle

Open Access
2019

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

Lam, M. T., Coppola, S., Krumbach, O. H. F., Prencipe, G., Insalaco, A., Cifaldi, C., Brigida, I., Zara, E., Scala, S., Di Cesare, S., Martinelli, S., Di Rocco, M., Pascarella, A., Niceta, M., Pantaleoni, F., Ciolfi, A., Netter, P., Carisey, A. F., Diehl, M., Akbarzadeh, M. & 30 others, Conti, F., Merli, P., Pastore, A., Levi Mortera, S., Camerini, S., Farina, L., Buchholzer, M., Pannone, L., Cao, T. N., Coban-Akdemir, Z. H., Jhangiani, S. N., Muzny, D. M., Gibbs, R. A., Basso-Ricci, L., Chiriaco, M., Dvorsky, R., Putignani, L., Carsetti, R., Janning, P., Stray-Pedersen, A., Erichsen, H. C., Rosti, V., Bracaglia, C., Palma, P., Finocchi, A., Locatelli, F., Cancrini, C., Aiuti, A., De Benedetti, F. & Tartaglia, M., Dec 2 2019, In : Journal of Experimental Medicine. 216, 12, p. 2778-2799 22 p.

Research output: Contribution to journalArticle

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

Lam, M. T., Coppola, S., Krumbach, O. H. F., Prencipe, G., Insalaco, A., Cifaldi, C., Brigida, I., Zara, E., Scala, S., Di Cesare, S., Martinelli, S., Di Rocco, M., Pascarella, A., Niceta, M., Pantaleoni, F., Ciolfi, A., Netter, P., Carisey, A. F., Diehl, M., Akbarzadeh, M. & 30 others, Conti, F., Merli, P., Pastore, A., Levi Mortera, S., Camerini, S., Farina, L., Buchholzer, M., Pannone, L., Cao, T. N., Coban-Akdemir, Z. H., Jhangiani, S. N., Muzny, D. M., Gibbs, R. A., Basso-Ricci, L., Chiriaco, M., Dvorsky, R., Putignani, L., Carsetti, R., Janning, P., Stray-Pedersen, A., Erichsen, H. C., Rosti, V., Bracaglia, C., Palma, P., Finocchi, A., Locatelli, F., Cancrini, C., Aiuti, A., De Benedetti, F. & Tartaglia, M., Dec 2 2019, In : The Journal of experimental medicine. 216, 12, p. 2778-2799 22 p.

Research output: Contribution to journalArticle

Open Access

Atypical IgM on T cells predict relapse and steroid dependence in idiopathic nephrotic syndrome

Colucci, M., Carsetti, R., Rosado, M. M., Cascioli, S., Bruschi, M., Candiano, G., Corpetti, G., Giardino, L., Serafinelli, J., Giannone, C., Ghiggeri, G. M., Rastaldi, M. P., Sitia, R., Emma, F. & Vivarelli, M., May 7 2019, In : Kidney International.

Research output: Contribution to journalArticle

Atypical IgM on T cells predict relapse and steroid dependence in idiopathic nephrotic syndrome

Colucci, M., Carsetti, R., Rosado, M. M., Cascioli, S., Bruschi, M., Candiano, G., Corpetti, G., Giardino, L., Serafinelli, J., Giannone, C., Ghiggeri, G. M., Rastaldi, M. P., Sitia, R., Emma, F. & Vivarelli, M., Jan 1 2019, In : Kidney International. 96, 4, p. 971-982

Research output: Contribution to journalArticle

Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity

Camponeschi, A., Gerasimcik, N., Wang, Y., Fredriksson, T., Chen, D., Farroni, C., Thorarinsdottir, K., Sjökvist Ottsjö, L., Aranburu, A., Cardell, S., Carsetti, R., Gjertsson, I., Mårtensson, I-L. & Grimsholm, O., Mar 21 2019, In : Frontiers in Immunology. 10, p. 534

Research output: Contribution to journalArticle

Rare TACI Mutation in a 3-Year-Old Boy With CVID Phenotype

Leonardi, L., Lorenzetti, G., Carsetti, R., Ferrari, S., Di Felice, A., Cinicola, B. & Duse, M., Oct 15 2019, In : Frontiers in Pediatrics. 7, 418.

Research output: Contribution to journalArticle

Open Access
2018

B cell phenotype in pediatric idiopathic nephrotic syndrome

Colucci, M., Carsetti, R., Cascioli, S., Serafinelli, J., Emma, F. & Vivarelli, M., Sep 28 2018, In : Pediatric Nephrology.

Research output: Contribution to journalArticle

CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α

Piper, C. J. M., Wilkinson, M. G. L., Deakin, C. T., Otto, G. W., Dowle, S., Duurland, C. L., Adams, S., Marasco, E., Rosser, E. C., Radziszewska, A., Carsetti, R., Ioannou, Y., Beales, P. L., Kelberman, D., Isenberg, D. A., Mauri, C., Nistala, K. & Wedderburn, L. R., 2018, In : Frontiers in Immunology. 9, p. 1372

Research output: Contribution to journalArticle

Dysregulated miR-155 and miR-125b Are Related to Impaired B-cell Responses in Down Syndrome

Farroni, C., Marasco, E., Marcellini, V., Giorda, E., Valentini, D., Petrini, S., D'Oria, V., Pezzullo, M., Cascioli, S., Scarsella, M., Ugazio, A. G., De Vincentiis, G. C., Grimsholm, O. & Carsetti, R., Nov 20 2018, In : Frontiers in Immunology. 9, p. 2683 12 p.

Research output: Contribution to journalArticle

Immunosuppression in Experimental Chagas Disease Is Mediated by an Alteration of Bone Marrow Stromal Cell Function During the Acute Phase of Infection

Müller, U., Schaub, G. A., Mossmann, H., Köhler, G., Carsetti, R. & Hölscher, C., 2018, In : Frontiers in Immunology. 9, p. 2794

Research output: Contribution to journalArticle

Long-term survival and phenotypic spectrum in heterotaxy syndrome: A 25-year follow-up experience

Baban, A., Cantarutti, N., Adorisio, R., Lombardi, R., Calcagni, G., Piano Mortari, E., Dallapiccola, B., Marino, B., Iorio, F. S., Carsetti, R., Digilio, M. C., Giannico, S., Drago, F. & Carotti, A., Oct 1 2018, In : International Journal of Cardiology. 268, p. 100-105 6 p.

Research output: Contribution to journalArticle

RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells

Rizzo, A., Di Giovangiulio, M., Stolfi, C., Franzè, E., Fehling, H-J., Carsetti, R., Giorda, E., Colantoni, A., Ortenzi, A., Rugge, M., Mescoli, C., Monteleone, G. & Fantini, M. C., Sep 2018, In : Cancer immunology research. 6, 9, p. 1082-1092 11 p.

Research output: Contribution to journalArticle

Spleen development is modulated by neonatal gut microbiota

Rosado, M. M., Aranburu, A., Scarsella, M., Cascioli, S., Giorda, E., Del Chierico, F., Mortera, S. L., Mortari, E. P., Petrini, S., Putignani, L. & Carsetti, R., Jul 2018, In : Immunology Letters. 199, p. 1-15 15 p.

Research output: Contribution to journalArticle

2017

Does Breastfeeding Protect Young Infants From Pertussis? Case-control Study and Immunologic Evaluation

Pertussis Study Group, Mar 2017, In : The Pediatric infectious disease journal. 36, 3, p. e48-e53

Research output: Contribution to journalArticle

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections

and the Pertussis study group, Jul 12 2017, In : BMC Infectious Diseases. 17, 1, 492.

Research output: Contribution to journalArticle

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections

Pertussis Study Group, Jul 12 2017, In : BMC Infectious Diseases. 17, 1, p. 492

Research output: Contribution to journalArticle

Parents as source of pertussis transmission in hospitalized young infants

Pertussis Study Group, Apr 2017, In : Infection. 45, 2, p. 171-178 8 p.

Research output: Contribution to journalArticle

Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells

The Pertussis Study Group, Sep 15 2017, In : Frontiers in Immunology. 8, SEP, 1158.

Research output: Contribution to journalArticle

Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells

Pertussis Study Group, 2017, In : Frontiers in Immunology. 8, p. 1158

Research output: Contribution to journalArticle

Severe pertussis infection in infants less than 6 months of age

Group, T. P. S., Stefanelli, P., Buttinelli, G., Vacca, P., Tozzi, A. E., Midulla, F., Carsetti, R., Fedele, G., Villani, A., Concato, C., Carannante, A., Fazio, C., Ausiello, C. M., Pandolfi, E., Gesualdo, F., Gonfiantini, M. V., Agricola, E., Cobianchi, F., Russo, L., de Horatio, L. T. & 4 others, Marcellini, V., Vennarucci, V. S., Nicolai, A. & Mattia, G. D., May 4 2017, In : Human Vaccines and Immunotherapeutics. 13, 5, p. 1073-1077 5 p.

Research output: Contribution to journalArticle

Severe pertussis infection in infants less than 6 months of age: Clinical manifestations and molecular characterization

The Pertussis Study Group, May 4 2017, In : Human Vaccines and Immunotherapeutics. 13, 5, p. 1073-1077 5 p.

Research output: Contribution to journalArticle

Severe Toxoplasma gondii infection in a member of a NFKB2-deficient family with T and B cell dysfunction

Maccari, ME., Scarselli, A., Di Cesare, S., Floris, M., Angius, A., Deodati, A., Chiriaco, M., Cambiaso, P., Corrente, S., Colafati, GS., Utz, PJ., Angelini, F., Fierabracci, A., Aiuti, A., Carsetti, R., Rosenberg, JM., Cappa, M., Rossi, P., Bacchetta, R. & Cancrini, C., 2017, In : Clinical Immunology. 183, 5, p. 273-277 5 p.

Research output: Contribution to journalArticle

The Vici syndrome protein EPG5 regulates intracellular nucleic acid trafficking linking autophagy to innate and adaptive immunity

Piano Mortari, E., Folgiero, V., Marcellini, V., Romania, P., Bellacchio, E., D'Alicandro, V., Bocci, C., Carrozzo, R., Martinelli, D., Petrini, S., Axiotis, E., Farroni, C., Locatelli, F., Schara, U., Pilz, D. T., Jungbluth, H., Dionisi-Vici, C. & Carsetti, R., Dec 1 2017, In : Autophagy. p. 1-16 16 p.

Research output: Contribution to journalArticle

2016

B-cell activation with CD40L or CpG measures the function of B-cell subsets and identifies specific defects in immunodeficient patients

Marasco, E., Farroni, C., Cascioli, S., Marcellini, V., Scarsella, M., Giorda, E., Piano Mortari, E., Leonardi, L., Scarselli, A., Valentini, D., Cancrini, C., Duse, M., Grimsholm, O. & Carsetti, R., Nov 1 2016, In : European Journal of Immunology. 47, 1, p. 131-143 13 p.

Research output: Contribution to journalArticle

B-cell hyperfunction in children with immune thrombocytopenic purpura persists after splenectomy

Giordano, P., Cascioli, S., Lassandro, G., Marcellini, V., Cardinale, F., Valente, F., Locatelli, F. & Carsetti, R., Mar 1 2016, In : Pediatric Research. 79, 2, p. 262-270 9 p.

Research output: Contribution to journalArticle

B Cell Reconstitution after Rituximab Treatment in Idiopathic Nephrotic Syndrome

Colucci, M., Carsetti, R., Cascioli, S., Casiraghi, F., Perna, A., Ravà, L., Ruggiero, B., Emma, F. & Vivarelli, M., 2016, In : Journal of the American Society of Nephrology : JASN. 27, 6, p. 1811-1822

Research output: Contribution to journalArticle

Does Breastfeeding Protect Young Infants from Pertussis? Case-Control Study and Immunologic Evaluation

Pandolfi, E., Gesualdo, F., Carloni, E., Villani, A., Midulla, F., Carsetti, R., Stefanelli, P., Fedele, G., Tozzi, A. E. & for the Pertussis Study Group, Nov 18 2016, (Accepted/In press) In : Pediatric Infectious Disease Journal.

Research output: Contribution to journalArticle

Effects of exposure to gradient magnetic fields emitted by nuclear magnetic resonance devices on clonogenic potential and proliferation of human hematopoietic stem cells

Iachininoto, M. G., Camisa, V., Leone, L., Pinto, R., Lopresto, V., Merla, C., Giorda, E., Carsetti, R., Zaffina, S., Podda, M. V., Teofili, L. & Grassi, C., May 1 2016, In : Bioelectromagnetics. 37, 4, p. 201-211 11 p.

Research output: Contribution to journalArticle

Effects of exposure to gradient magnetic fields emitted by nuclear magnetic resonance devices on clonogenic potential and proliferation of human hematopoietic stem cells

Iachininoto, M. G., Camisa, V., Leone, L., Pinto, R., Lopresto, V., Merla, C., Giorda, E., Carsetti, R., Zaffina, S., Podda, M. V., Teofili, L. & Grassi, C., May 1 2016, In : Bioelectromagnetics. 37, 4, p. 201-211 11 p.

Research output: Contribution to journalArticle

Heterotaxy syndrome with and without spleen: Different infection risk and management

Piano Mortari, E., Baban, A., Cantarutti, N., Bocci, C., Adorisio, R. & Carsetti, R., Nov 15 2016, In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Human B-cell memory is shaped by age- and tissue-specific T-independent and GC-dependent events

Aranburu, A., Piano Mortari, E., Baban, A., Giorda, E., Cascioli, S., Marcellini, V., Scarsella, M., Ceccarelli, S., Corbelli, S., Cantarutti, N., De Vito, R., Inserra, A., Nicolosi, L., Lanfranchi, A., Porta, F., Cancrini, C., Finocchi, A. & Carsetti, R., 2016, (Accepted/In press) In : European Journal of Immunology.

Research output: Contribution to journalArticle

Monitoring perinatal gut microbiota in mouse models by mass spectrometry approaches: Parental genetic background and breastfeeding effects

Mortera, S. L., Del Chierico, F., Vernocchi, P., Rosado, M. M., Cavola, A., Chierici, M., Pieroni, L., Urbani, A., Carsetti, R., Lante, I., Dallapiccola, B. & Putignani, L., Sep 26 2016, In : Frontiers in Microbiology. 7, 1523.

Research output: Contribution to journalArticle

Monitoring perinatal gut microbiota in mouse models by mass spectrometry approaches: Parental genetic background and breastfeeding effects

Mortera, S. L., Del Chierico, F., Vernocchi, P., Rosado, M. M., Cavola, A., Chierici, M., Pieroni, L., Urbani, A., Carsetti, R., Lante, I., Dallapiccola, B. & Putignani, L., Sep 26 2016, In : Frontiers in Microbiology. 7, 1523.

Research output: Contribution to journalArticle

Novel STAT1 gain-of-function mutation and suppurative infections

Giardino, G., Somma, D., Cirillo, E., Ruggiero, G., Terrazzano, G., Rubino, V., Ursini, M. V., Vairo, D., Badolato, R., Carsetti, R., Leonardi, A., Puel, A. & Pignata, C., Mar 1 2016, In : Pediatric Allergy and Immunology. 27, 2, p. 220-223 4 p.

Research output: Contribution to journalArticle

Parents as source of pertussis transmission in hospitalized young infants

Fedele, G., Carollo, M., Palazzo, R., Stefanelli, P., Pandolfi, E., Gesualdo, F., Tozzi, A. E., Carsetti, R., Villani, A., Nicolai, A., Midulla, F., Ausiello, C. M., Leone, P., Schiavoni, I., Buttinelli, G., Gonfiantini, M. V., Agricola, E., Russo, L., Ferretti, B., Campagna, I. & 7 others, Marcellini, V., Concato, C., Frassanito, A., Nenna, R., Mattia, G. D., Rizzo, C. & The Pertussis Study Group, Sep 10 2016, (Accepted/In press) In : Infection. p. 1-8 8 p.

Research output: Contribution to journalArticle

2015

B cells from nuclear factor kB essential modulator deficient patients fail to differentiate to antibody secreting cells in response to TLR9 ligand

Giardino, G., Cirillo, E., Gallo, V., Esposito, T., Fusco, F., Conte, M. I., Quinti, I., Ursini, M. V., Carsetti, R. & Pignata, C., Dec 1 2015, In : Clinical Immunology. 161, 2, p. 131-135 5 p.

Research output: Contribution to journalArticle

Generation of switched memory B cells in response to vaccination in Down syndrome children and their siblings

Valentini, D., Marcellini, V., Bianchi, S., Villani, A., Facchini, M., Donatelli, I., Castrucci, M. R., Marasco, E., Farroni, C. & Carsetti, R., Nov 27 2015, In : Vaccine. 33, 48, p. 6689-6696 8 p.

Research output: Contribution to journalArticle

Hematopoietic activity in putative mouse primordial germ cell populations

Scaldaferri, M. L., Klinger, F. G., Farini, D., Di Carlo, A., Carsetti, R., Giorda, E. & De Felici, M., May 1 2015, In : Mechanisms of Development. 136, p. 53-63 11 p.

Research output: Contribution to journalArticle

High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells

Puglisi, M. A., Cenciarelli, C., Tesori, V., Cappellari, M., Martini, M., Di Francesco, A. M., Giorda, E., Carsetti, R., Ricci-Vitiani, L. & Gasbarrini, A., Aug 1 2015, In : Journal of Pathology. 236, 4, p. 479-490 12 p.

Research output: Contribution to journalArticle

Increased serum IgM, immunodeficiency, and autoimmunity: A clinical series

Picchianti Diamanti, A., Rosado, M. M., Scarsella, M., Ceccarelli, S., Laganà, B., D'Amelio, R. & Carsetti, R., Dec 1 2015, In : International Journal of Immunopathology and Pharmacology. 28, 4, p. 547-556 10 p.

Research output: Contribution to journalArticle

Inhibition of B-cell proliferation and antibody production by mesenchymal stromal cells is mediated by T cells

Rosado, M. M., Bernardo, M. E., Scarsella, M., Conforti, A., Giorda, E., Biagini, S., Cascioli, S., Rossi, F., Guzzo, I., Vivarelli, M., Dello Strologo, L., Emma, F., Locatelli, F. & Carsetti, R., Jan 1 2015, In : Stem Cells and Development. 24, 1, p. 93-103 11 p.

Research output: Contribution to journalArticle

Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency

Scarselli, A., Di Cesare, S., Capponi, C., Cascioli, S., Romiti, M. L., Di Matteo, G., Simonetti, A., Palma, P., Finocchi, A., Lucarelli, B., Pinto, R. M., Rana, I., Palumbo, G., Caniglia, M., Rossi, P., Carsetti, R., Cancrini, C. & Aiuti, A., Apr 15 2015, In : Journal of Clinical Immunology. 35, 4, p. 373-383 11 p.

Research output: Contribution to journalArticle

Reduced numbers of switched memory B cells with high terminal differentiation potential in Down syndrome

Carsetti, R., Valentini, D., Marcellini, V., Scarsella, M., Marasco, E., Giustini, F., Bartuli, A., Villani, A. & Ugazio, A. G., Mar 1 2015, In : European Journal of Immunology. 45, 3, p. 903-914 12 p.

Research output: Contribution to journalArticle

2014

Abatacept (cytotoxic T lymphocyte antigen 4-immunoglobulin) improves B cell function and regulatory T cell inhibitory capacity in rheumatoid arthritis patients non-responding to anti-tumour necrosis factor-α agents

Picchianti Diamanti, A., Rosado, M. M., Scarsella, M., Germano, V., Giorda, E., Cascioli, S., Laganà, B., D'Amelio, R. & Carsetti, R., 2014, In : Clinical and Experimental Immunology. 177, 3, p. 630-640 11 p.

Research output: Contribution to journalArticle

A metaproteomic pipeline to identify newborn mouse gut phylotypes

Del Chierico, F., Petrucca, A., Mortera, S. L., Vernocchi, P., Rosado, M. M., Pieroni, L., Carsetti, R., Urbani, A. & Putignani, L., Jan 31 2014, In : Journal of Proteomics. 97, p. 17-26 10 p.

Research output: Contribution to journalArticle

A refined approach to detect and measure minimal residual disease in childhood acute myeloid leukemia by flow cytometry

Capolunghi, F., Capponi, C., De Stefani, B., Luciani, M., Locatelli, F., Muraca, M. & Carsetti, R., Mar 2014, In : American Journal of Hematology. 89, 3, p. 343-344 2 p.

Research output: Contribution to journalArticle