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Article
2020

3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From Calcium-Channel Modulators Properties to Multidrug-Resistance Reverting Activity

Micucci, M., Viale, M., Chiarini, A., Spinelli, D., Frosini, M., Tavani, C., Maccagno, M., Bianchi, L., Gangemi, R. & Budriesi, R., Feb 27 2020, In : Molecules (Basel, Switzerland). 25, 5

Research output: Contribution to journalArticle

Open Access
2019

Synthesis and Anti-proliferative Activity of Novel Polysubstitued Indazole Derivatives

Bassou, O., Chicha, H., Allam, A., Monticone, M., Gangemi, R., Maric, I., Viale, M. & Rakib, E. M., Jan 1 2019, In : Journal of Heterocyclic Chemistry. 56, 1, p. 343-348 6 p.

Research output: Contribution to journalArticle

2017

IL-27 mediates HLA class i up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells

Carbotti, G., Nikpoor, A. R., Vacca, P., Gangemi, R., Giordano, C., Campelli, F., Ferrini, S. & Fabbi, M., Oct 11 2017, In : Journal of Experimental and Clinical Cancer Research. 36, 1, 140.

Research output: Contribution to journalArticle

IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells

Carbotti, G., Nikpoor, A. R., Vacca, P., Gangemi, R., Giordano, C., Campelli, F., Ferrini, S. & Fabbi, M., Oct 11 2017, In : Journal of Experimental and Clinical Cancer Research. 36, 1, p. 140

Research output: Contribution to journalArticle

The biology of uveal melanoma

Amaro, A., Gangemi, R., Piaggio, F., Angelini, G., Barisione, G., Ferrini, S. & Pfeffer, U., Mar 1 2017, In : Cancer and Metastasis Reviews. 36, 1, p. 109-140 32 p.

Research output: Contribution to journalArticle

2016

A highly invasive subpopulation of MDA-MB-231 breast cancer cells shows accelerated growth, differential chemoresistance, features of apocrine tumors and reduced tumorigenicity in vivo

Amaro, A., Angelini, G., Mirisola, V., Esposito, A. I., Reverberi, D., Matis, S., Maffei, M., Giaretti, W., Viale, M., Gangemi, R., Emionite, L., Astigiano, S., Cilli, M., Bachmeier, B. E., Killian, P. H., Albini, A. & Pfeffer, U., Oct 18 2016, In : Oncotarget. 7, 42, p. 68803-68820 18 p.

Research output: Contribution to journalArticle

Potentiation of cisplatin-induced antiproliferative and apoptotic activities by the antiarrhythmic drug procainamide hydrochloride

Viale, M., Fenoglio, C., De Totero, D., Prigione, I., Cassano, A., Vincenti, A., Bocca, P., Gangemi, R. & Mariggiò, M. A., Jun 1 2016, In : Pharmacological Reports. 68, 3, p. 654-661 8 p.

Research output: Contribution to journalArticle

2015

CD133-Positive Cells from Non-Small Cell Lung Cancer Show Distinct Sensitivity to Cisplatin and Afatinib

Alama, A., Gangemi, R., Ferrini, S., Barisione, G., Orengo, A. M., Truini, M., Bello, M. G. D. & Grossi, F., Jun 1 2015, In : Archivum Immunologiae et Therapiae Experimentalis. 63, 3, p. 207-214 8 p.

Research output: Contribution to journalArticle

Folate-cyclodextrin conjugates as carriers of the platinum(IV) complex LA-12

Giglio, V., Oliveri, V., Viale, M., Gangemi, R., Natile, G., Intini, F. P. & Vecchio, G., 2015, In : ChemPlusChem. 80, 3, p. 536-543 8 p.

Research output: Contribution to journalArticle

Human renal normal, tumoral, and cancer stem cells express membrane-bound interleukin-15 isoforms displaying different functions

Azzi, S., Gallerne, C., Romei, C., Le Coz, V., Gangemi, R., Khawam, K., Devocelle, A., Gu, Y., Bruno, S., Ferrini, S., Chouaib, S., Eid, P., Azzarone, B. & Giron-Michel, J., 2015, In : Neoplasia (United States). 17, 6, p. 509-517 9 p.

Research output: Contribution to journalArticle

Potential role of soluble c-met as a new Candidate biomarker of metastatic uveal melanoma

Barisione, G., Fabbi, M., Gino, A., Queirolo, P., Orgiano, L., Spano, L., Picasso, V., Pfeffer, U., Mosci, C., Jager, M. J., Ferrini, S. & Gangemi, R., Sep 1 2015, In : JAMA Ophthalmology. 133, 9, p. 1013-1021 9 p.

Research output: Contribution to journalArticle

2014

ADAM10 correlates with uveal melanoma metastasis and promotes in vitro invasion

Gangemi, R., Amaro, A., Gino, A., Barisione, G., Fabbi, M., Pfeffer, U., Brizzolara, A., Queirolo, P., Salvi, S., Boccardo, S., Gualco, M., Spagnolo, F., Jager, M. J., Mosci, C., Rossello, A. & Ferrini, S., Nov 1 2014, In : Pigment Cell and Melanoma Research. 27, 6, p. 1138-1148 11 p.

Research output: Contribution to journalArticle

Synthesis and antitumor activity of some substituted indazole derivatives

Abbassi, N., Rakib, E. M., Chicha, H., Bouissane, L., Hannioui, A., Aiello, C., Gangemi, R., Castagnola, P., Rosano, C. & Viale, M., 2014, In : Archiv der Pharmazie. 347, 6, p. 423-431 9 p.

Research output: Contribution to journalArticle

2013

ABCB1 structural models, molecular docking, and synthesis of new oxadiazolothiazin-3-one inhibitors

Rosano, C., Viale, M., Cosimelli, B., Severi, E., Gangemi, R., Ciogli, A., De Totero, D. & Spinelli, D., Aug 8 2013, In : ACS Medicinal Chemistry Letters. 4, 8, p. 694-698 5 p.

Research output: Contribution to journalArticle

Evaluation of the anti-proliferative activity of three new pyrazole compounds in sensitive and resistant tumor cell lines

Viale, M., Anzaldi, M., Aiello, C., Fenoglio, C., Albicini, F., Emionite, L., Gangemi, R. & Balbi, A., 2013, In : Pharmacological Reports. 65, 3, p. 717-723 7 p.

Research output: Contribution to journalArticle

Glycosylated copper(ii) ionophores as prodrugs for β-glucosidase activation in targeted cancer therapy

Oliveri, V., Viale, M., Caron, G., Aiello, C., Gangemi, R. & Vecchio, G., Feb 14 2013, In : Dalton Transactions. 42, 6, p. 2023-2034 12 p.

Research output: Contribution to journalArticle

2012

Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression

Gangemi, R., Mirisola, V., Barisione, G., Fabbi, M., Brizzolara, A., Lanza, F., Mosci, C., Salvi, S., Gualco, M., Truini, M., Angelini, G., Boccardo, S., Cilli, M., Airoldi, I., Queirolo, P., Jager, M. J., Daga, A., Pfeffer, U. & Ferrini, S., Jan 13 2012, In : PLoS One. 7, 1, e29989.

Research output: Contribution to journalArticle

Synthesis, antiproliferative and apoptotic activities of N-(6(4)-indazolyl)-benzenesulfonamide derivatives as potential anticancer agents

Abbassi, N., Chicha, H., Rakib, E. M., Hannioui, A., Alaoui, M., Hajjaji, A., Geffken, D., Aiello, C., Gangemi, R., Rosano, C. & Viale, M., Nov 2012, In : European Journal of Medicinal Chemistry. 57, p. 240-249 10 p.

Research output: Contribution to journalArticle

Targeting cancer-initiating cell drug-resistance: A Sroadmap to a new-generation of cancer therapies?

Alama, A., Orengo, A. M., Ferrini, S. & Gangemi, R., May 2012, In : Drug Discovery Today. 17, 9-10, p. 435-442 8 p.

Research output: Contribution to journalArticle

2011

New perspectives in glioma immunotherapy

Daga, A., Bottino, C., Castriconi, R., Gangemi, R. & Ferrini, S., Aug 2011, In : Current Pharmaceutical Design. 17, 23, p. 2439-2467 29 p.

Research output: Contribution to journalArticle

Synthesis and biological evaluation of novel pyrazole derivatives with anticancer activity

Balbi, A., Anzaldi, M., MacCi, C., Aiello, C., Mazzei, M., Gangemi, R., Castagnola, P., Miele, M., Rosano, C. & Viale, M., Nov 2011, In : European Journal of Medicinal Chemistry. 46, 11, p. 5293-5309 17 p.

Research output: Contribution to journalArticle

2009

Cancer stem cells: A new paradigm for understanding tumor growth and progression and drug resistance

Gangemi, R., Paleari, L., Orengo, A. M., Cesario, A., Chessa, L., Ferrini, S. & Russo, P., 2009, In : Current Medicinal Chemistry. 16, 14, p. 1688-1703 16 p.

Research output: Contribution to journalArticle

SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity

Gangemi, R. M. R., Griffero, F., Marubbi, D., Perera, M., Capra, M. C., Malatesta, P., Ravetti, G. L., Zona, G. L., Daga, A. & Corte, G., Jan 2009, In : Stem Cells. 27, 1, p. 40-48 9 p.

Research output: Contribution to journalArticle

2007

Glioma immunotherapy by IL-21 gene-modified cells or by recombinant IL-21 involves antibody responses

Daga, A., Orengo, A. M., Gangemi, R. M. R., Marubbi, D., Perera, M., Comes, A., Ferrini, S. & Corte, G., Oct 15 2007, In : International Journal of Cancer. 121, 8, p. 1756-1763 8 p.

Research output: Contribution to journalArticle

2006

Effects of Emx2 inactivation on the gene expression profile of neural precursors

Gangemi, R. M. R., Daga, A., Muzio, L., Marubbi, D., Cocozza, S., Perera, M., Verardo, S., Bordo, D., Griffero, F., Capra, M. C., Mallamaci, A. & Corte, G., Jan 2006, In : European Journal of Neuroscience. 23, 2, p. 325-334 10 p.

Research output: Contribution to journalArticle

Regulatory genes controlling cell fate choice in embryonic and adult neural stem cells

Gangemi, R. M. R., Perera, M. & Corte, G., Apr 2004, In : Journal of Neurochemistry. 89, 2, p. 286-306 21 p.

Research output: Contribution to journalArticle

2001

Emx2 in adult neural precursor cells

Gangemi, R. M. R., Daga, A., Marubbi, D., Rosatto, N., Capra, M. C. & Corte, G., 2001, In : Mechanisms of Development. 109, 2, p. 323-329 7 p.

Research output: Contribution to journalArticle

Emx2 promotes symmetric cell divisions and a multipotential fate in precursors from the cerebral cortex

Heins, N., Cremisi, F., Malatesta, P., Gangemi, R. M. R., Corte, G., Price, J., Goudreau, G., Gruss, P. & Götz, M., 2001, In : Molecular and Cellular Neuroscience. 18, 5, p. 485-502 18 p.

Research output: Contribution to journalArticle

2000

Late apoptotic effects of taxanes on K562 erythroleukemia cells: Apoptosis is delayed upstream of caspase-3 activation

Gangemi, R. M. R., Santamaria, B., Bargellesi, A., Cosulich, E. & Fabbi, M., 2000, In : International Journal of Cancer. 85, 4, p. 527-533 7 p.

Research output: Contribution to journalArticle

1996

Apoptosis susceptibility of human carcinoma and leukemia cell lines to taxol: Relationship with cell cycle and drug concentration

Gangemi, R. M. R., Costa, G., Fulco, R. A., D'Aquino, S. & Aronadio, O., 1996, In : Annals of the New York Academy of Sciences. 784, p. 550-554 5 p.

Research output: Contribution to journalArticle

Biological parameters in breast cancer

Costa, G., Lascari, G., Aragona, M., Ferlazzo, G., Adamo, V., Gangemi, R., Geraci, O., Pastura, G., Mesiti, M. & Castagnetta, L., 1996, In : Annals of the New York Academy of Sciences. 784, p. 521-524 4 p.

Research output: Contribution to journalArticle

1995

Spontaneous apoptosis in human thymocytes

Tiso, M., Gangemi, R., Severi, A. B., Pizzolitto, S., Fabbi, M. & Risso, A., 1995, In : American Journal of Pathology. 147, 2, p. 434-444 11 p.

Research output: Contribution to journalArticle

Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell death

Gangemi, R. M. R., Tiso, M., Marchetti, C., Severi, A. B. & Fabbi, M., Sep 1995, In : Cancer Chemotherapy and Pharmacology. 36, 5, p. 385-392 8 p.

Research output: Contribution to journalArticle

1994

A novel 120-kDa antigen shared by immature human thymocytes and long-term-activated T cells

Fabbi, M., Tiso, M., Gangemi, R. M. R., Favre, A., Demartini, P. & Bargellesi-Severi, A., Jan 1994, In : European Journal of Immunology. 24, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Corrigendum: The role of VL gene structural determinants in the fine specificity of anti-DNA antibodies (Autoimmunity (1994) 18 no 1 (65-75))

Singh, A. K., Gangemi, R. M. R. & Barrett, K. J., 1994, In : Autoimmunity. 18, 3, p. 227 1 p.

Research output: Contribution to journalArticle

The role of VL gene structural determinants in the fine specificity of anti-DNA antibodies

Singh, A. K., Gangemi, R. M. R. & Barrett, K. J., 1994, In : Autoimmunity. 18, 3, p. 227 1 p.

Research output: Contribution to journalArticle

The role of VL gene structural determinants in the fine specificity of anti-DNA antibodies

Singh, A. K. & Gangemi, R. M. R., 1994, In : Autoimmunity. 18, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

1993

Independently derived IgG anti-DNA autoantibodies from two lupus-prone mouse strains express a VH gene that is not present in most murine strains

Gangemi, R. M. R., Singh, A. K. & Barrett, K. J., Nov 1 1993, In : Journal of Immunology. 151, 9, p. 4660-4671 12 p.

Research output: Contribution to journalArticle

1989

Anti-T12, an anti-CD6 monoclonal antibody, can activate human T lymphocytes

Gangemi, R. M. R., Swack, J. A., Gaviria, D. M. & Romain, P. L., 1989, In : Journal of Immunology. 143, 8, p. 2439-2447 9 p.

Research output: Contribution to journalArticle

Structural characterization of CD6: Properties of two distinct epitopes involved in T cell activation

Swack, J. A., Gangemi, R. M. R., Rudd, C. E., Morimoto, C., Schlossman, S. F. & Romain, P. L., 1989, In : Molecular Immunology. 26, 11, p. 1037-1049 13 p.

Research output: Contribution to journalArticle