• 18259 Citations
  • 61 h-Index
1992 …2019
If you made any changes in Pure these will be visible here soon.

Research Output 1992 2019

  • 18259 Citations
  • 61 h-Index
  • 236 Article
  • 8 Review article
2019

A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study

Gamucci, T., Pizzuti, L., Natoli, C., Mentuccia, L., Sperduti, I., Barba, M., Sergi, D., Iezzi, L., Maugeri-Saccà, M., Vaccaro, A., Magnolfi, E., Gelibter, A., Barchiesi, G., Magri, V., D’Onofrio, L., Cassano, A., Rossi, E., Botticelli, A., Moscetti, L., Omarini, C. & 29 othersFabbri, M. A., Scinto, A. F., Corsi, D., Carbognin, L., Mazzotta, M., Bria, E., Foglietta, J., Samaritani, R., Garufi, C., Mariani, L., Barni, S., Mirabelli, R., Sarmiento, R., Graziano, V., Santini, D., Marchetti, P., Tonini, G., Di Lauro, L., Sanguineti, G., Paoletti, G., Tomao, S., De Maria, R., Veltri, E., Paris, I., Giotta, F., Latorre, A., Giordano, A., Ciliberto, G. & Vici, P., Feb 1 2019, In : Cancer Biology and Therapy. 20, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

Taxoids
Observational Studies
Retrospective Studies
Breast Neoplasms
Maintenance

Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases

Grassi, L., Alfonsi, R., Francescangeli, F., Signore, M., De Angelis, M. L., Addario, A., Costantini, M., Flex, E., Ciolfi, A., Pizzi, S., Bruselles, A., Pallocca, M., Simone, G., Haoui, M., Falchi, M., Milella, M., Sentinelli, S., Di Matteo, P., Stellacci, E., Gallucci, M. & 4 othersMuto, G., Tartaglia, M., De Maria, R. & Bonci, D., Feb 27 2019, In : Cell death & disease. 10, 3, p. 201

Research output: Contribution to journalArticle

Organoids
Regenerative Medicine
Kidney
Kidney Neoplasms
Neoplasms

Two-Step Co-Immunoprecipitation (TIP)

Sciuto, M. R., Coppola, V., Iannolo, G., De Maria, R. & Haas, T. L., Jan 1 2019, In : Current Protocols in Molecular Biology. 125, 1, e80.

Research output: Contribution to journalArticle

Immunoprecipitation
Proteins
Burkitt Lymphoma
Nucleic Acids
Chromatin
2018

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells

Manic, G., Signore, M., Sistigu, A., Russo, G., Corradi, F., Siteni, S., Musella, M., Vitale, S., Angelis, M. L. D., Pallocca, M., Amoreo, C. A., Sperati, F., Franco, S. D., Barresi, S., Policicchio, E., Luca, G. D., Nicola, F. D., Mottolese, M., Zeuner, A., Fanciulli, M. & 6 othersStassi, G., Maugeri-Sacca, M., Baiocchi, M., Tartaglia, M., Vitale, I. & Maria, R. D., May 1 2018, In : Gut. 67, 5, p. 903-917 15 p.

Research output: Contribution to journalArticle

Polyploidy
Neoplastic Stem Cells
DNA Replication
Colorectal Neoplasms
Protein Array Analysis

Coexisting YAP expression and TP53 missense mutations delineates a molecular scenario unexpectedly associated with better survival outcomes in advanced gastric cancer

Pallocca, M., Goeman, F., De Nicola, F., Melucci, E., Sperati, F., Terrenato, I., Pizzuti, L., Casini, B., Gallo, E., Amoreo, C. A., Vici, P., Di Lauro, L., Buglioni, S., Diodoro, M. G., Pescarmona, E., Mazzotta, M., Barba, M., Fanciulli, M., De Maria, R., Ciliberto, G. & 1 othersMaugeri-Saccà, M., Sep 4 2018, In : Journal of Translational Medicine. 16, 1, p. 247

Research output: Contribution to journalArticle

Chemotherapy
Missense Mutation
Stomach Neoplasms
Mutation
Survival

Conditionally reprogrammed cells (CRC) methodology does not allow the in vitro expansion of patient-derived primary and metastatic lung cancer cells

Sette, G., Salvati, V., Giordani, I., Pilozzi, E., Quacquarini, D., Duranti, E., De Nicola, F., Pallocca, M., Fanciulli, M., Falchi, M., Pallini, R., De Maria, R. & Eramo, A., 2018, In : International Journal of Cancer. 143, 1, p. 88-99 12 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Lung
Cell Culture Techniques
Neoplasms
Epithelial Cells

GLUT 1 receptor expression and circulating levels of fasting glucose in high grade serous ovarian cancer

Pizzuti, L., Sergi, D., Mandoj, C., Antoniani, B., Sperati, F., Chirico, A., Lauro, L. D., Valle, M., Garofalo, A., Vizza, E., Corrado, G., Tomao, F., Rinaldi, M., Carpano, S., Maugeri-Sacca, M., Conti, L., Digiesi, G., Marchetti, P., Maria, R. D., Giordano, A. & 3 othersBarba, M., Carosi, M. A. & Vici, P., Feb 1 2018, In : Journal of Cellular Physiology. 233, 2, p. 1396-1401 6 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Fasting
Glucose
Staining and Labeling
Biomarkers

HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome

di Martino, S., Amoreo, C. A., Nuvoli, B., Galati, R., Strano, S., Facciolo, F., Alessandrini, G., Pass, H. I., Ciliberto, G., Blandino, G., De Maria, R. & Cioce, M., Mar 2018, In : Oncogene. 37, 10, p. 1369-1385 17 p.

Research output: Contribution to journalArticle

Interleukin-8
Drug Therapy
Phenotype
Neoplasms
Mesothelioma
3 Citations (Scopus)

Micro-economics of apoptosis in cancer: NcRNAs modulation of BCL-2 family members

Villanova, L., Careccia, S., De Maria, R. & Fiori, M. E., Apr 1 2018, In : International Journal of Molecular Sciences. 19, 4, 958.

Research output: Contribution to journalReview article

Untranslated RNA
apoptosis
B-Cell Lymphoma
Cell death
RNA
4 Citations (Scopus)

miR-663 sustains NSCLC by inhibiting mitochondrial outer membrane permeabilization (MOMP) through PUMA/BBC3 and BTG2 article

Fiori, M. E., Villanova, L., Barbini, C., De Angelis, M. L. & De Maria, R., Feb 1 2018, In : Cell Death and Disease. 9, 2, 49.

Research output: Contribution to journalArticle

Mitochondrial Membranes
Non-Small Cell Lung Carcinoma
MicroRNAs
Neoplasms
Cell Death

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 149 othersBlomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K-M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K-M., DeBerardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J-C., Martin, S. J., Martinou, J-C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H-U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalArticle

Terminology
Cell Death
Apoptosis
Cell Aging
Autophagy

Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 30 othersBlomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, FK-M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., De Maria, R., Fimia, G. M., Lugli, E., Malorni, W., Manic, G., Pagano, M., Piacentini, M., Sistigu, A., Tait, S. W. G. & Melino, G., 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalArticle

Palbociclib plus endocrine therapy in HER2 negative, hormonal receptor-positive, advanced breast cancer: A real-world experience

Pizzuti, L., Giordano, A., Michelotti, A., Mazzotta, M., Natoli, C., Gamucci, T., De Angelis, C., Landucci, E., Diodati, L., Iezzi, L., Mentuccia, L., Fabbri, A., Barba, M., Sanguineti, G., Marchetti, P., Tomao, S., Mariani, L., Paris, I., Lorusso, V., Vallarelli, S. & 30 othersCassano, A., Airoldi, F., Orlandi, A., Moscetti, L., Sergi, D., Sarobba, M. G., Tonini, G., Santini, D., Sini, V., Veltri, E., Vaccaro, A., Ferrari, L., De Tursi, M., Tinari, N., Grassadonia, A., Greco, F., Botticelli, A., La Verde, N., Zamagni, C., Rubino, D., Cortesi, E., Magri, V., Pomati, G., Cazzaniga, M., Mancini, M., Carpano, S., De Maria, R., Sperduti, I., Ciliberto, G. & Vici, P., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

exemestane
Confidence Intervals
Breast Neoplasms
Toxicity
Therapeutics

Renal cancer: new models and approach for personalizing therapy

Martino, S. D., Luca, G. D., Grassi, L., Federici, G., Alfonsi, R., Signore, M., Addario, A., Salvo, L. D., Francescangeli, F., Sanchez, M., Tirelli, V., Muto, G., Sperduti, I., Sentinelli, S., Costantini, M., Pasquini, L., Milella, M., Haoui, M., Simone, G., Gallucci, M. & 2 othersMaria, R. D. & Bonci, D., Sep 5 2018, In : Journal of experimental & clinical cancer research : CR. 37, 1, p. 4 1 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Neoplasms
Therapeutics
Protein Array Analysis
Population

Replication stress response in cancer stem cells as a target for chemotherapy

Manic, G., Sistigu, A., Corradi, F., Musella, M., Maria, R. D. & Vitale, I., Dec 1 2018, In : Seminars in Cancer Biology. 53, p. 31-41 11 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Drug Therapy
DNA Damage
Multipotent Stem Cells
Recombinational DNA Repair

Replication stress response in cancer stem cells as a target for chemotherapy

Manic, G., Sistigu, A., Corradi, F., Musella, M., De Maria, R. & Vitale, I., Dec 1 2018, In : Seminars in Cancer Biology. 53, p. 31-41 11 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Drug Therapy
DNA Damage
Multipotent Stem Cells
Recombinational DNA Repair

The clinical significance of PD-L1 in advanced gastric cancer is dependent on ARID1A mutations and ATM expression

Buglioni, S., Melucci, E., Sperati, F., Pallocca, M., Terrenato, I., De Nicola, F., Goeman, F., Casini, B., Amoreo, C. A., Gallo, E., Diodoro, M. G., Pescarmona, E., Vici, P., Sergi, D., Pizzuti, L., Di Lauro, L., Mazzotta, M., Barba, M., Fanciulli, M., Vitale, I. & 3 othersDe Maria, R., Ciliberto, G. & Maugeri-Saccà, M., 2018, In : OncoImmunology. 7, 8, p. e1457602

Research output: Contribution to journalArticle

Stomach Neoplasms
DNA Repair
DNA Damage
Mutation
Survival
1 Citation (Scopus)

The clinical significance of PD-L1 in advanced gastric cancer is dependent on ARID1A mutations and ATM expression

Buglioni, S., Melucci, E., Sperati, F., Pallocca, M., Terrenato, I., De Nicola, F., Goeman, F., Casini, B., Amoreo, C. A., Gallo, E., Diodoro, M. G., Pescarmona, E., Vici, P., Sergi, D., Pizzuti, L., Di Lauro, L., Mazzotta, M., Barba, M., Fanciulli, M., Vitale, I. & 3 othersDe Maria, R., Ciliberto, G. & Maugeri-Saccà, M., Apr 19 2018, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

Stomach Neoplasms
DNA Repair
DNA Damage
Mutation
Survival

The Hippo pathway in normal development and cancer

Maugeri-Saccà, M. & De Maria, R., Jun 2018, In : Pharmacology and Therapeutics. 186, p. 60-72 13 p.

Research output: Contribution to journalReview article

Drug Repositioning
Neoplasms
Organ Size
Neoplastic Stem Cells
Bone Resorption
1 Citation (Scopus)

Two-Step Coimmunoprecipitation (TIP) enables efficient and highly selective isolation of native protein complexes

Sciuto, M. R., Warnken, U., Schnölzer, M., Valvo, C., Brunetto, L., Boe, A., Biffoni, M., Krammer, P. H., De Maria, R. & Haas, T. L., May 1 2018, In : Molecular and Cellular Proteomics. 17, 5, p. 993-1009 17 p.

Research output: Contribution to journalArticle

Proteins
Nucleic Acids
T-cells
Proteomics
Mass spectrometry
2017
13 Citations (Scopus)

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells

Manic, G., Signore, M., Sistigu, A., Russo, G., Corradi, F., Siteni, S., Musella, M., Vitale, S., De Angelis, M. L., Pallocca, M., Amoreo, C. A., Sperati, F., Di Franco, S., Barresi, S., Policicchio, E., De Luca, G., De Nicola, F., Mottolese, M., Zeuner, A., Fanciulli, M. & 6 othersStassi, G., Maugeri-Saccà, M., Baiocchi, M., Tartaglia, M., Vitale, I. & De Maria, R., Apr 7 2017, In : Gut.

Research output: Contribution to journalArticle

Polyploidy
Neoplastic Stem Cells
DNA Replication
Colorectal Neoplasms
Protein Array Analysis
18 Citations (Scopus)

Integrin a7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma

Haas, T. L., Sciuto, R., Brunetto, L., Valvo, C., Signore, M., Fiori, M. E., Martino, S. D., Giannetti, S., Morgante, L., Boe, A., Patrizii, M., Warnken, U., Schnölzer, M., Ciolfi, A., Stefano, C. D., Biffoni, M., Ricci-Vitiani, L., Pallini, R. & Maria, R. D., 2017, In : Cell Stem Cell. 21, 1, p. 35-50.e9

Research output: Contribution to journalArticle

11 Citations (Scopus)

Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma

Po, A., Silvano, M., Miele, E., Capalbo, C., Eramo, A., Salvati, V., Todaro, M., Besharat, Z. M., Catanzaro, G., Cucchi, D., Coni, S., Di Marcotullio, L., Canettieri, G., Vacca, A., Stassi, G., De Smaele, E., Tartaglia, M., Screpanti, I., De Maria, R. & Ferretti, E., Aug 10 2017, In : Oncogene. 36, 32, p. 4641-4652 12 p.

Research output: Contribution to journalArticle

Growth
Neoplasms
Neoplastic Stem Cells
Stromal Cells
Epigenomics
11 Citations (Scopus)

Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma

Po, A., Silvano, M., Miele, E., Capalbo, C., Eramo, A., Salvati, V., Todaro, M., Besharat, Z. M., Catanzaro, G., Cucchi, D., Coni, S., Di Marcotullio, L., Canettieri, G., Vacca, A., Stassi, G., De Smaele, E., Tartaglia, M., Screpanti, I., De Maria, R. & Ferretti, E., Aug 10 2017, In : Oncogene. 36, 32, p. 4641-4652 12 p.

Research output: Contribution to journalArticle

Growth
Neoplasms
Neoplastic Stem Cells
Stromal Cells
Epigenomics
4 Citations (Scopus)

Protein drug target activation homogeneity in the face of intratumor heterogeneity: Implications for precision medicine

Parasido, E. M., Silvestri, A., Canzonieri, V., Belluco, C., Diodoro, M. G., Milione, M., Melotti, F., De Maria, R., Liotta, L., Petricoin, E. F. & Pierobon, M., Jan 1 2017, In : Oncotarget. 8, 30, p. 48534-48544 11 p.

Research output: Contribution to journalArticle

Precision Medicine
Neoplasms
Proteins
Laser Capture Microdissection
Protein Array Analysis
4 Citations (Scopus)

Protein drug target activation homogeneity in the face of intratumor heterogeneity: Implications for precision medicine

Parasido, E. M., Silvestri, A., Canzonieri, V., Belluco, C., Diodoro, M. G., Milione, M., Melotti, F., De Maria, R., Liotta, L., Petricoin, E. F. & Pierobon, M., Jan 1 2017, In : Oncotarget. 8, 30, p. 48534-48544 11 p.

Research output: Contribution to journalArticle

Precision Medicine
Neoplasms
Proteins
Laser Capture Microdissection
Protein Array Analysis
4 Citations (Scopus)

Protein drug target activation homogeneity in the face of intra-tumor heterogeneity: implications for precision medicine

Parasido, E. M., Silvestri, A., Canzonieri, V., Belluco, C., Diodoro, M. G., Milione, M., Melotti, F., De Maria, R., Liotta, L., Petricoin, E. F. & Pierobon, M., Jul 25 2017, In : Oncotarget. 8, 30, p. 48534-48544 11 p.

Research output: Contribution to journalArticle

Precision Medicine
Neoplasms
Proteins
Laser Capture Microdissection
Protein Array Analysis
2016
63 Citations (Scopus)

A microRNA code for prostate cancer metastasis

Bonci, D., Coppola, V., Patrizii, M., Addario, A., Cannistraci, A., Francescangeli, F., Pecci, R., Muto, G., Collura, D., Bedini, R., Zeuner, A., Valtieri, M., Sentinelli, S., Benassi, M. S., Gallucci, M., Carlini, P., Piccolo, S. & De Maria, R., Mar 3 2016, In : Oncogene. 35, 9, p. 1180-1192 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
Bone Neoplasms

A microRNA code for prostate cancer metastasis

Bonci, D., Coppola, V., Patrizii, M., Addario, A., Cannistraci, A., Francescangeli, F., Pecci, R., Muto, G., Collura, D., Bedini, R., Zeuner, A., Valtieri, M., Sentinelli, S., Benassi, M. S., Gallucci, M., Carlini, P., Piccolo, S. & De Maria, R. M., Mar 3 2016, In : Oncogene. 35, 9, p. 1180-1192 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
Bone Neoplasms

A microRNA code for prostate cancer metastasis

Bonci, D., Coppola, V., Patrizii, M., Addario, A., Cannistraci, A., Francescangeli, F., Pecci, R., Muto, G., Collura, D., Bedini, R., Zeuner, A., Valtieri, M., Sentinelli, S., Benassi, M. S., Gallucci, M., Carlini, P., Piccolo, S. & De Maria, R. M., Mar 3 2016, In : Oncogene. 35, 9, p. 1180-1192 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
Bone Neoplasms
9 Citations (Scopus)

Analysis of the hippo transducers TAZ and YAP in cervical cancer and its microenvironment

Buglioni, S., Vici, P., Sergi, D., Pizzuti, L., Di Lauro, L., Antoniani, B., Sperati, F., Terrenato, I., Carosi, M., Gamucci, T., Vincenzoni, C., Mariani, L., Vizza, E., Venuti, A., Sanguineti, G., Gadducci, A., Barba, M., Natoli, C., Vitale, I., Mottolese, M. & 2 othersDe Maria, R. & Maugeri-Saccà, M., Jun 2 2016, In : OncoImmunology. 5, 6, e1160187.

Research output: Contribution to journalArticle

Tumor Microenvironment
Transducers
Uterine Cervical Neoplasms
Tumor-Infiltrating Lymphocytes
Neoplasms

Cancer stem cell-based models of colorectal cancer reveal molecular determinants of therapy resistance

De Angelis, M. L., Zeuner, A., Policicchio, E., Russo, G., Bruselles, A., Signore, M., Vitale, S., De Luca, G., Pilozzi, E., Boe, A., Stassi, G., Ricci-Vitiani, L., Amoreo, C. A., Pagliuca, A., Francescangeli, F., Tartaglia, M., De Maria, R. M. & Baiocchi, M., 2016, In : Stem cells translational medicine. 5, 4, p. 511-523 13 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Colorectal Neoplasms
Therapeutics
Cell Separation
Epidermal Growth Factor Receptor
16 Citations (Scopus)

Cancer stem cell-based models of colorectal cancer reveal molecular determinants of therapy resistance

De Angelis, M. L., Zeuner, A., Policicchio, E., Russo, G., Bruselles, A., Signore, M., Vitale, S., De Luca, G., Pilozzi, E., Boe, A., Stassi, G., Ricci-Vitiani, L., Amoreo, C. A., Pagliuca, A., Francescangeli, F., Tartaglia, M., De Maria, R. & Baiocchi, M., 2016, In : Stem cells translational medicine. 5, 4, p. 511-523 13 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Colorectal Neoplasms
Therapeutics
Cell Separation
Epidermal Growth Factor Receptor
8 Citations (Scopus)

Cancer stem cells as a potential therapeutic target in thyroid carcinoma (Review)

Vicari, L., Colarossi, C., Giuffrida, D., De Maria, R. & Memeo, L., Oct 1 2016, In : Oncology Letters. 12, 4, p. 2254-2260 7 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Thyroid Neoplasms
Endocrine Gland Neoplasms
Therapeutics
Neoplasms
6 Citations (Scopus)

DNA damage and repair biomarkers in cervical cancer patients treated with neoadjuvant chemotherapy: An exploratory analysis

Vici, P., Buglioni, S., Sergi, D., Pizzuti, L., Di Lauro, L., Antoniani, B., Sperati, F., Terrenato, I., Carosi, M., Gamucci, T., Dattilo, R., Bartucci, M., Vincenzoni, C., Mariani, L., Vizza, E., Sanguineti, G., Gadducci, A., Vitale, I., Barba, M., De Maria, R. & 2 othersMottolese, M. & Maugeri-Saccà, M., Mar 1 2016, In : PLoS One. 11, 3, e149872.

Research output: Contribution to journalArticle

uterine cervical neoplasms
Chemotherapy
Biomarkers
DNA repair
DNA Repair
94 Citations (Scopus)

Epithelial-mesenchymal transition: A new target in anticancer drug discovery

Marcucci, F., Stassi, G. & De Maria, R., May 1 2016, In : Nature Reviews Drug Discovery. 15, 5, p. 311-325 15 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Drug Discovery
Phenotype
Neoplasms
Embryonic Development
14 Citations (Scopus)

Hippo pathway and breast cancer stem cells

Maugeri-Saccà, M. & De Maria, R., Mar 1 2016, In : Critical Reviews in Oncology/Hematology. 99, p. 115-122 8 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Breast Neoplasms
Breast
Neoplasms
Human Mammary Glands
12 Citations (Scopus)

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

Di Martile, M., Desideri, M., De Luca, T., Gabellini, C., Buglioni, S., Eramo, A., Sette, G., Milella, M., Rotili, D., Mai, A., Carradori, S., Secci, D., De Maria, R., Del Bufalo, D. & Trisciuoglio, D., 2016, In : Oncotarget. 7, 10, p. 11332-11348 17 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Neoplastic Stem Cells
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Cell Line
4 Citations (Scopus)

hMENA11a contributes to HER3-mediated resistance to PI3K inhibitors in HER2-overexpressing breast cancer cells

Trono, P., Di Modugno Damiani, F., Circo, R., Spada, S., Di Benedetto, A., Melchionna, R., Palermo, B., Matteoni, S., Soddu, S., Mottolese, M., De Maria, R. & Nisticò, P., Feb 18 2016, In : Oncogene. 35, 7, p. 887-896 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Breast Neoplasms
Cell Survival
Protein Isoforms
Therapeutics
3 Citations (Scopus)

HMG-CoAR expression in male breast cancer: Relationship with hormone receptors, Hippo transducers and survival outcomes

Di Benedetto, A., Mottolese, M., Sperati, F., Ercolani, C., Di Lauro, L., Pizzuti, L., Vici, P., Terrenato, I., Shaaban, A. M., Sundara-Rajan, S., Humphries, M. P., Barba, M., Speirs, V., De Maria, R. & Maugeri-Saccà, M., Oct 7 2016, In : Scientific Reports. 6, 35121.

Research output: Contribution to journalArticle

Male Breast Neoplasms
Transducers
Hormones
Survival
Mevalonic Acid
27 Citations (Scopus)

Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes with Different Clinical Outcome

Marziali, G., Signore, M., Buccarelli, M., Grande, S., Palma, A., Biffoni, M., Rosi, A., D'Alessandris, Q. G., Martini, M., Larocca, L. M., De Maria, R., Pallini, R. & Ricci-Vitiani, L., Feb 9 2016, In : Scientific Reports. 6, 21557.

Research output: Contribution to journalArticle

Glioblastoma
Proteomics
Stem Cells
Magnetic Resonance Spectroscopy
Phenotype
12 Citations (Scopus)

Normal vs cancer thyroid stem cells: The road to transformation

Zane, M., Scavo, E., Catalano, V., Bonanno, M., Todaro, M., De Maria, R. & Stassi, G., Feb 18 2016, In : Oncogene. 35, 7, p. 805-815 11 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Thyroid Neoplasms
Stem Cells
Thyroid Gland
Neoplasms
4 Citations (Scopus)

Numb expression contributes to the maintenance of an undifferentiated state in human epidermis

Iannolo, G., Sciuto, M. R., Buccheri, S., Colarossi, C., de Maria, R., Memeo, L. & Conaldi, P. G., 2016, In : Cell Transplantation. 25, 2, p. 353-364 12 p.

Research output: Contribution to journalArticle

Stem cells
Epidermis
Skin
Stem Cells
Maintenance

Numb expression contributes to the maintenance of an undifferentiated state in human epidermis

Iannolo, G., Sciuto, M. R., Buccheri, S., Colarossi, C., De Maria, R. M., Memeo, L. & Conaldi, P. G., 2016, In : Cell Transplantation. 25, 2, p. 353-364 12 p.

Research output: Contribution to journalArticle

Stem cells
Epidermis
Skin
Stem Cells
Maintenance
3 Citations (Scopus)

Presurgical window of opportunity trial design as a platform for testing anticancer drugs: Pros, cons and a focus on breast cancer

Maugeri-Saccà, M., Barba, M., Vici, P., Pizzuti, L., Sergi, D., Catenaro, T., Di Lauro, L., Mottolese, M., Santini, D., Milella, M. & De Maria, R., Oct 1 2016, In : Critical Reviews in Oncology/Hematology. 106, p. 132-142 11 p.

Research output: Contribution to journalReview article

Breast Neoplasms
Pharmaceutical Preparations
Patient Harm
Therapeutics
Drug Combinations
24 Citations (Scopus)

Targeting immune response with therapeutic vaccines in premalignant lesions and cervical cancer: hope or reality from clinical studies

Vici, P., Pizzuti, L., Mariani, L., Zampa, G., Santini, D., Di Lauro, L., Gamucci, T., Natoli, C., Marchetti, P., Barba, M., Maugeri-Saccà, M., Sergi, D., Tomao, F., Vizza, E., Di Filippo, S., Paolini, F., Curzio, G., Corrado, G., Michelotti, A., Sanguineti, G. & 3 othersGiordano, A., De Maria, R. & Venuti, A., Oct 2 2016, In : Expert Review of Vaccines. 15, 10, p. 1327-1336 10 p.

Research output: Contribution to journalReview article

Papillomavirus Vaccines
Uterine Cervical Neoplasms
Cervical Intraepithelial Neoplasia
Vaccines
Oncogenes

Targeting immune response with therapeutic vaccines in premalignant lesions and cervical cancer: hope or reality from clinical studies

Vici, P., Pizzuti, L., Mariani, L., Zampa, G., Santini, D., Di Lauro, L., Gamucci, T., Natoli, C., Marchetti, P., Barba, M., Maugeri-Saccà, M., Sergi, D., Tomao, F., Vizza, E., Di Filippo, S., Paolini, F., Curzio, G., Corrado, G., Michelotti, A., Sanguineti, G. & 3 othersGiordano, A., De Maria, R. M. & Venuti, A., Oct 2 2016, In : Expert Review of Vaccines. 15, 10, p. 1327-1336 10 p.

Research output: Contribution to journalReview article

Papillomavirus Vaccines
Uterine Cervical Neoplasms
Cervical Intraepithelial Neoplasia
Vaccines
Oncogenes
20 Citations (Scopus)

The Hippo transducers TAZ/YAP and their target CTGF in male breast cancer

Di Benedetto, A., Mottolese, M., Sperati, F., Ercolani, C., Di Lauro, L., Pizzuti, L., Vici, P., Terrenato, I., Sperduti, I., Shaaban, A. M., Sundara-Rajan, S., Barba, M., Speirs, V., De Maria, R. & Maugeri-Saccà, M., 2016, In : Oncotarget. 7, 28, p. 43188-43198 11 p.

Research output: Contribution to journalArticle

Male Breast Neoplasms
Transducers
Survival
Neoplasms
Phenotype
13 Citations (Scopus)

Topographic expression of the Hippo transducers TAZ and YAP in triple-negative breast cancer treated with neoadjuvant chemotherapy

Vici, P., Ercolani, C., Romano, V., Pizzuti, L., Di Lauro, L., Sperati, F., Terrenato, I., Gamucci, T., Natoli, C., Di Filippo, F., Botti, C., Barba, M., Mottolese, M., De Maria, R. & Maugeri-Saccà, M., Apr 2 2016, In : Journal of Experimental and Clinical Cancer Research. 35, 1, 62.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Transducers
Drug Therapy
Neoplasms
Stromal Cells

"Triple positive" early breast cancer: An observational multicenter retrospective analysis of outcome

Vici, P., Pizzuti, L., Sperduti, I., Frassoldati, A., Natoli, C., Gamucci, T., Tomao, S., Michelotti, A., Moscetti, L., Gori, S., Baldini, E., Giotta, F., Cassano, A., Santini, D., Giannarelli, D., Di Lauro, L., Corsi, D., Marchetti, P., Sini, V., Sergi, D. & 13 othersBarba, M., Maugeri-Saccà, M., Russillo, M., Mentuccia, L., D'Onofrio, L., Iezzi, L., Scinto, A. F., Da Ros, L., Bertolini, I., Basile, M. L., Rossi, V., De Maria, R. M. & Montemurro, F., 2016, In : Oncotarget. 7, 14, p. 17932-17944 13 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Survival
Recurrence
Neoplasms
Adjuvant Chemotherapy