• 47 Citations
  • 4 h-Index
20172018
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Fingerprint Dive into the research topics where Salvatore Castaldo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Huntington Disease Medicine & Life Sciences
Blood-Brain Barrier Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Sphingolipids Medicine & Life Sciences
Animal Models Medicine & Life Sciences
Therapeutic Uses Medicine & Life Sciences
Blood Vessels Medicine & Life Sciences
Fluorescein Medicine & Life Sciences

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Research Output 2017 2018

  • 47 Citations
  • 4 h-Index
  • 6 Article
  • 1 Comment/debate
1 Citation (Scopus)

Correction: Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease (Scientific Reports DOI: 10.1038/s41598-017-05709-y)

Di Pardo, A., Amico, E., Basit, A., Armirotti, A., Joshi, P., Neely, M. D., Vuono, R., Castaldo, S., Digilio, A. F., Scalabrì, F., Pepe, G., Elifani, F., Madonna, M., Jeong, S. K., Park, B. M., D'Esposito, M., Bowman, A. B., Barker, R. A. & Maglione, V., Dec 1 2018, In : Scientific Reports. 8, 1, 8266.

Research output: Contribution to journalComment/debate

Huntington Disease
sphingosine 1-phosphate
7 Citations (Scopus)

Stimulation of S1PR5 with A-971432, a selective agonist, preserves blood-brain barrier integrity and exerts therapeutic effect in an animal model of Huntington's disease

Di Pardo, A., Castaldo, S., Amico, E., Pepe, G., Marracino, F., Capocci, L., Giovannelli, A., Madonna, M., van Bergeijk, J., Buttari, F., van der Kam, E. & Maglione, V., Jul 15 2018, In : Human Molecular Genetics. 27, 14, p. 2490-2501 12 p.

Research output: Contribution to journalArticle

Huntington Disease
Therapeutic Uses
Blood-Brain Barrier
Lysosphingolipid Receptors
Animal Models
2 Citations (Scopus)
Neurodegenerative diseases
Blood-Brain Barrier
Fluorescein
Intravenous Infusions
Neurodegenerative Diseases
15 Citations (Scopus)
5 Downloads (Pure)

Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease

Di Pardo, A., Amico, E., Basit, A., Armirotti, A., Joshi, P., Neely, D. M., Vuono, R., Castaldo, S., Digilio, A. F., Scalabrì, F., Pepe, G., Elifani, F., Madonna, M., Jeong, S. K., Park, B. M., D'Esposito, M., Bowman, A. B., Barker, R. A. & Maglione, V., Dec 1 2017, In : Scientific Reports. 7, 1, 5280.

Research output: Contribution to journalArticle

Open Access
File
Huntington Disease
Lipids
Lipid Metabolism
Neurodegenerative Diseases
Homeostasis
8 Citations (Scopus)

De novo synthesis of sphingolipids is defective in experimental models of Huntington's disease

Pardo, A. D., Basit, A., Armirotti, A., Amico, E., Castaldo, S., Pepe, G., Marracino, F., Buttari, F., Digilio, A. F. & Maglione, V., Dec 19 2017, In : Frontiers in Neuroscience. 11, DEC, 698.

Research output: Contribution to journalArticle

Sphingolipids
Huntington Disease
Theoretical Models
Corpus Striatum
Disease Susceptibility