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Fingerprint Dive into the research topics where Salvatore Castaldo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Huntington Disease Medicine & Life Sciences
Blood-Brain Barrier Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Animal Models Medicine & Life Sciences
Sphingolipids Medicine & Life Sciences
Phenotype Medicine & Life Sciences
Curcumin Medicine & Life Sciences
Therapeutic Uses Medicine & Life Sciences

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Research Output 2017 2019

Curcumin dietary supplementation ameliorates disease phenotype in an animal model of Huntington's disease

Elifani, F., Amico, E., Pepe, G., Capocci, L., Castaldo, S., Rosa, P., Montano, E., Pollice, A., Madonna, M., Filosa, S., Calogero, A., Maglione, V., Crispi, S. & Di Pardo, A., Oct 20 2019, In : Human Molecular Genetics.

Research output: Contribution to journalArticle

Curcumin
Huntington Disease
Dietary Supplements
Animal Models
Phenotype

Stimulation of Sphingosine Kinase 1 (SPHK1) Is Beneficial in a Huntington's Disease Pre-clinical Model

Di Pardo, A., Pepe, G., Castaldo, S., Marracino, F., Capocci, L., Amico, E., Madonna, M., Giova, S., Jeong, S. K., Park, B-M., Park, B. D. & Maglione, V., 2019, In : Frontiers in Molecular Neuroscience. 12, p. 100

Research output: Contribution to journalArticle

Huntington Disease
Therapeutics
Poisons
Disease Progression
sphingosine kinase

Correction: Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease (Scientific Reports DOI: 10.1038/s41598-017-05709-y)

Di Pardo, A., Amico, E., Basit, A., Armirotti, A., Joshi, P., Neely, M. D., Vuono, R., Castaldo, S., Digilio, A. F., Scalabrì, F., Pepe, G., Elifani, F., Madonna, M., Jeong, S. K., Park, B. M., D'Esposito, M., Bowman, A. B., Barker, R. A. & Maglione, V., Dec 1 2018, In : Scientific Reports. 8, 1, 8266.

Research output: Contribution to journalComment/debate

Huntington Disease
sphingosine 1-phosphate

Stimulation of S1PR5 with A-971432, a selective agonist, preserves blood-brain barrier integrity and exerts therapeutic effect in an animal model of Huntington's disease

Di Pardo, A., Castaldo, S., Amico, E., Pepe, G., Marracino, F., Capocci, L., Giovannelli, A., Madonna, M., van Bergeijk, J., Buttari, F., van der Kam, E. & Maglione, V., Jul 15 2018, In : Human Molecular Genetics. 27, 14, p. 2490-2501 12 p.

Research output: Contribution to journalArticle

Huntington Disease
Therapeutic Uses
Blood-Brain Barrier
Lysosphingolipid Receptors
Animal Models
Neurodegenerative diseases
Blood-Brain Barrier
Fluorescein
Intravenous Infusions
Neurodegenerative Diseases