1992 …2019

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2019
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2018

A NUMB-EFA6B-ARF6 recycling route controls apically restricted cell protrusions and mesenchymal motility

Zobel, M., Disanza, A., Senic-Matuglia, F., Franco, M., Colaluca, I. N., Confalonieri, S., Bisi, S., Barbieri, E., Caldieri, G., Sigismund, S., Pece, S., Chavrier, P., Di Fiore, P. P. & Scita, G., Sep 1 2018, In : Journal of Cell Biology. 217, 9, p. 3161-3182 22 p.

Research output: Contribution to journalArticle

A Numb-Mdm2 fuzzy complex reveals an isoformspecific involvement of Numb in breast cancer

Colaluca, I. N., Basile, A., Freiburger, L., D'Uva, V., Disalvatore, D., Vecchi, M., Confalonieri, S., Tosoni, D., Cecatiello, V., Malabarba, M. G., Yang, C. J., Kainosho, M., Sattler, M., Mapelli, M., Pece, S. & di Fiore, P. P., Feb 1 2018, In : Journal of Cell Biology. 217, 2, p. 745-762 18 p.

Research output: Contribution to journalArticle

A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration

Salvatore, C., Malinverno, C., Neumann, B., Tischer, C., Palamidessi, A., Frittoli, E., Panagiotakopoulou, M., Disanza, A., Malet-Engra, G., Nastaly, P., Galli, C., Luise, C., Bertalot, G., Pece, S., Di Fiore, P. P., Gauthier, N., Ferrari, A., Maiuri, P. & Scita, G., Dec 1 2018, In : Nature Communications. 9, 1, 1475.

Research output: Contribution to journalArticle

High USP6NL Levels in Breast Cancer Sustain Chronic AKT Phosphorylation and GLUT1 Stability Fueling Aerobic Glycolysis

Avanzato, D., Pupo, E., Ducano, N., Isella, C., Bertalot, G., Luise, C., Pece, S., Bruna, A., Rueda, O. M., Caldas, C., Di Fiore, P. P., Sapino, A. & Lanzetti, L., Jul 1 2018, In : Cancer Research. 78, 13, p. 3432-3444 13 p.

Research output: Contribution to journalArticle

2017

Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function

Gulluni, F., Martini, M., De Santis, M. C., Campa, C. C., Ghigo, A., Margaria, J. P., Ciraolo, E., Franco, I., Ala, U., Annaratone, L., Disalvatore, D., Bertalot, G., Viale, G., Noatynska, A., Compagno, M., Sigismund, S., Montemurro, F., Thelen, M., Fan, F., Meraldi, P. & 6 others, Marchiò, C., Pece, S., Sapino, A., Chiarle, R., Di Fiore, P. P. & Hirsch, E., 2017, In : Cancer Cell. 32, 4, p. 444

Research output: Contribution to journalArticle

Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function

Gulluni, F., Martini, M., De Santis, M. C., Campa, C. C., Ghigo, A., Margaria, J. P., Ciraolo, E., Franco, I., Ala, U., Annaratone, L., Disalvatore, D., Bertalot, G., Viale, G., Noatynska, A., Compagno, M., Sigismund, S., Montemurro, F., Thelen, M., Fan, F., Meraldi, P. & 6 others, Marchiò, C., Pece, S., Sapino, A., Chiarle, R., Di Fiore, P. P. & Hirsch, E., Oct 9 2017, In : Cancer Cell. 32, 4, p. 444-459.e7

Research output: Contribution to journalArticle

Pre-clinical validation of a selective anti-cancer stem cell therapy for Numb-deficient human breast cancers

Tosoni, D., Pambianco, S., Ekalle Soppo, B., Zecchini, S., Bertalot, G., Pruneri, G., Viale, G., Di Fiore, P. P. & Pece, S., May 1 2017, In : EMBO Molecular Medicine. 9, 5, p. 655-671 17 p.

Research output: Contribution to journalArticle

The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries

Grasso, S., Chapelle, J., Salemme, V., Aramu, S., Russo, I., Vitale, N., Verdun di Cantogno, L., Dallaglio, K., Castellano, I., Amici, A., Centonze, G., Sharma, N., Lunardi, S., Cabodi, S., Cavallo, F., Lamolinara, A., Stramucci, L., Moiso, E., Provero, P., Albini, A. & 11 others, Sapino, A., Staaf, J., Di Fiore, P. P., Bertalot, G., Pece, S., Tosoni, D., Confalonieri, S., Iezzi, M., Di Stefano, P., Turco, E. & Defilippi, P., Mar 16 2017, In : Nature Communications. 8, p. 14797

Research output: Contribution to journalArticle

The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries

Grasso, S., Chapelle, J., Salemme, V., Aramu, S., Russo, I., Vitale, N., Di Cantogno, L. V., Dallaglio, K., Castellano, I., Amici, A., Centonze, G., Sharma, N., Lunardi, S., Cabodi, S., Cavallo, F., Lamolinara, A., Stramucci, L., Moiso, E., Provero, P., Albini, A. & 11 others, Sapino, A., Staaf, J., Di Fiore, P. P., Bertalot, G., Pece, S., Tosoni, D., Confalonieri, S., Iezzi, M., Di Stefano, P., Turco, E. & Defilippi, P., Mar 16 2017, In : Nature Communications. 8, 14797.

Research output: Contribution to journalArticle

2016

A Trust-Based Pact in Research Biobanks. From Theory to Practice

Sanchini, V., Bonizzi, G., Disalvatore, D., Monturano, M., Pece, S., Viale, G., Di Fiore, P. P. & Boniolo, G., May 2016, In : Bioethics. 30, 4, p. 260-71 12 p.

Research output: Contribution to journalArticle

Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling

Calcagnì, A., Kors, L., Verschuren, E., De Cegli, R., Zampelli, N., Nusco, E., Confalonieri, S., Bertalot, G., Pece, S., Settembre, C., Malouf, G., Leemans, J. C., de Heer, E., Salvatore, M., Peters, D., Di Fiore, P. P. & Ballabio, A., Sep 26 2016, In : eLife. 5, September, e17047.

Research output: Contribution to journalArticle

Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling

Calcagnì, A., Kors, L., Verschuren, E., De Cegli, R., Zampelli, N., Nusco, E., Confalonieri, S., Bertalot, G., Pece, S., Settembre, C., Malouf, G. G., Leemans, J. C., de Heer, E., Salvatore, M., Peters, D. J. M., Di Fiore, P. P. & Ballabio, A., Sep 26 2016, In : eLife. 5, September, e17047.

Research output: Contribution to journalArticle

2015

A Trust-Based Pact in Research Biobanks. From Theory to Practice

Sanchini, V., Bonizzi, G., Disalvatore, D., Monturano, M., Pece, S., Viale, G., Di Fiore, P. P. & Boniolo, G., 2015, (Accepted/In press) In : Bioethics.

Research output: Contribution to journalArticle

Redox-Mediated Suberoylanilide Hydroxamic Acid Sensitivity in Breast Cancer

Chiaradonna, F., Barozzi, I., Miccolo, C., Bucci, G., Palorini, R., Fornasari, L., Botrugno, O. A., Pruneri, G., Masullo, M., Passafaro, A., Galimberti, V. E., Fantin, V. R., Richon, V. M., Pece, S., Viale, G., Di Fiore, P. P., Draetta, G., Pelicci, P. G., Minucci, S. & Chiocca, S., Jul 1 2015, In : Antioxidants and Redox Signaling. 23, 1, p. 15-29 15 p.

Research output: Contribution to journalArticle

The Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells

Tosoni, D., Zecchini, S., Coazzoli, M., Colaluca, I., Mazzarol, G., Rubio, A., Caccia, M., Villa, E., Zilian, O., Di Fiore, P. P. & Pece, S., Nov 23 2015, In : Journal of Cell Biology. 211, 4, p. 845-862 18 p.

Research output: Contribution to journalArticle

2014

FlowFit: A bioconductor package to estimate proliferation in cell-tracking dye studies

Rambaldi, D., Pece, S. & Di Fiore, P. P., Jul 15 2014, In : Bioinformatics. 30, 14, p. 2060-2065 6 p.

Research output: Contribution to journalArticle

HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels

Puca, F., Colamaio, M., Federico, A., Gemei, M., Tosti, N., Bastos, A. U., Del Vecchio, L., Pece, S., Battista, S. & Fusco, A., 2014, In : Oncotarget. 5, 10, p. 3234-3245 12 p.

Research output: Contribution to journalArticle

2013

TPT1/ TCTP-regulated pathways in phenotypic reprogramming

Amson, R., Pece, S., Marine, J. C., Fiore, P. P. D. & Telerman, A., Jan 2013, In : Trends in Cell Biology. 23, 1, p. 37-46 10 p.

Research output: Contribution to journalArticle

2012

Reciprocal repression between P53 and TCTP

Amson, R., Pece, S., Lespagnol, A., Vyas, R., Mazzarol, G., Tosoni, D., Colaluca, I., Viale, G., Rodrigues-Ferreira, S., Wynendaele, J., Chaloin, O., Hoebeke, J., Marine, J. C., Di Fiore, P. P. & Telerman, A., Jan 2012, In : Nature Medicine. 18, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

Trusted consent and research biobanks: Towards a 'new alliance' between researchers and donors

Boniolo, G., Di Fiore, P. P. & Pece, S., Feb 2012, In : Bioethics. 26, 2, p. 93-100 8 p.

Research output: Contribution to journalArticle

2011

Cobalamin deficiency-induced changes of epidermal growth factor (EGF)-receptor expression and EGF levels in rat spinal cord

Mutti, E., Magnaghi, V., Veber, D., Faroni, A., Pece, S., Di Fiore, P. P. & Scalabrino, G., Feb 28 2011, In : Brain Research. 1376, p. 23-30 8 p.

Research output: Contribution to journalArticle

Genomic characterization of asymptomatic CT-detected lung cancers

Belloni, E., Veronesi, G., Micucci, C., Javan, S., Minardi, S. P., Venturini, E., Maisonneuve, P., Volorio, S., Riboni, M., Bellomi, M., Scanagatta, P., Taliento, G., Pelosi, G., Pece, S., Spaggiari, L. & Pelicci, P. G., Mar 3 2011, In : Oncogene. 30, 9, p. 1117-1126 10 p.

Research output: Contribution to journalArticle

NUMB-ing down cancer by more than just a NOTCH

Pece, S., Confalonieri, S., R. Romano, P. & Di Fiore, P. P., Jan 2011, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1815, 1, p. 26-43 18 p.

Research output: Contribution to journalArticle

2010
2009

Alterations of the Notch pathway in lung cancer

Westhoff, B., Colaluca, I. N., D'Ario, G., Donzelli, M., Tosoni, D., Volorio, S., Pelosi, G., Spaggiari, L., Mazzarol, G., Viale, G., Pece, S. & Di Fiore, P. P., Dec 19 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 52, p. 22293-22298 6 p.

Research output: Contribution to journalArticle

Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor

Confalonieri, S., Quarto, M., Goisis, G., Nuciforo, P., Donzelli, M., Jodice, G., Pelosi, G., Viale, G., Pece, S. & Di Fiore, P. P., Aug 20 2009, In : Oncogene. 28, 33, p. 2959-2968 10 p.

Research output: Contribution to journalArticle

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

Rustighi, A., Tiberi, L., Soldano, A., Napoli, M., Nuciforo, P., Rosato, A., Kaplan, F., Capobianco, A., Pece, S., Di Fiore, P. P. & Del Sal, G., 2009, In : Nature Cell Biology. 11, 2, p. 133-142 10 p.

Research output: Contribution to journalArticle

2008

Breast cancer metastases are molecularly distinct from their primary tumors

Vecchi, M., Confalonieri, S., Nuciforo, P., Viganò, M. A., Capra, M., Bianchi, M., Nicosia, D., Bianchi, F., Galimberti, V., Viale, G., Palermo, G., Riccardi, A., Campanini, R., Daidone, M. G., Pierotti, M. A., Pece, S. & Di Fiore, P. P., Apr 3 2008, In : Oncogene. 27, 15, p. 2148-2158 11 p.

Research output: Contribution to journalArticle

NUMB controls p53 tumour suppressor activity

Colaluca, I. N., Tosoni, D., Nuciforo, P., Senic-Matuglia, F., Galimberti, V., Viale, G., Pece, S. & Di Fiore, P. P., Jan 3 2008, In : Nature. 451, 7174, p. 76-80 5 p.

Research output: Contribution to journalArticle

2007

Prognostic implications of Numb immunoreactivity in salivary gland carcinomas

Maiorano, E., Favia, G., Pece, S., Resta, L., Maisonneuve, P., Di Fiore, P. P., Capodiferro, S., Urbani, U. & Viale, G., Oct 2007, In : International Journal of Immunopathology and Pharmacology. 20, 4, p. 779-789 11 p.

Research output: Contribution to journalArticle

2006

In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients

Mey, V., Giovannetti, E., De Braud, F., Nannizzi, S., Curigliano, G., Verweij, F., De Cobelli, O., Pece, S., Del Tacca, M. & Danesi, R., Aug 7 2006, In : British Journal of Cancer. 95, 3, p. 289-297 9 p.

Research output: Contribution to journalArticle

2005

Cyclin D3 immunoreactivity is an independent predictor of survival in laryngeal squamous cell carcinoma

Pruneri, G., Pignataro, L., Valentini, S., Fabris, S., Maisonneuve, P., Carboni, N., Pece, S., Capra, M., Del Curto, B., Neri, A. & Viale, G., Jan 1 2005, In : Clinical Cancer Research. 11, 1, p. 242-248 7 p.

Research output: Contribution to journalArticle

2004

Endocytosis and cancer

Polo, S., Pece, S. & Di Fiore, P. P., Apr 2004, In : Current Opinion in Cell Biology. 16, 2, p. 156-161 6 p.

Research output: Contribution to journalArticle

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

Pece, S., Serresi, M., Santolini, E., Capra, M., Hulleman, E., Galimberti, V., Zurrida, S., Maisonneuve, P., Viale, G. & Di Fiore, P. P., Oct 25 2004, In : Journal of Cell Biology. 167, 2, p. 215-221 7 p.

Research output: Contribution to journalArticle

2002

E-cadherin and Hakai: Signalling, remodeling or destruction?

Pece, S. & Gutkind, J. S., 2002, In : Nature Cell Biology. 4, 4

Research output: Contribution to journalArticle

2001

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B

Montaner, S., Sodhi, A., Pece, S., Mesri, E. A. & Gutkind, J. S., Mar 15 2001, In : Cancer Research. 61, 6, p. 2641-2648 8 p.

Research output: Contribution to journalArticle

2000

Loss of PTEN expression leading to high Akt activation in human multiple myelomas

Hyun, T., Yam, A., Pece, S., Xie, X., Zhang, J., Miki, T., Gutkind, J. S. & Li, W., Nov 15 2000, In : Blood. 96, 10, p. 3560-3568 9 p.

Research output: Contribution to journalArticle

1999

Helicobacter pylori infection and host cell responses

Di Leo, A., Messa, C., Russo, F., Linsalata, M., Amati, L., Caradonna, L., Pece, S., Pellegrino, N. M., Caccavo, D., Antonaci, S. & Jirillo, E., 1999, In : Immunopharmacology and Immunotoxicology. 21, 4, p. 803-846 44 p.

Research output: Contribution to journalArticle

Lactoferrin-lipid A-lipopolysaccharide interaction: Inhibition by anti- human lactoferrin monoclonal antibody AGM 10.14

Caccavo, D., Afeltra, A., Pece, S., Giuliani, G., Freudenberg, M., Galanos, C. & Jirillo, E., 1999, In : Infection and Immunity. 67, 9, p. 4668-4672 5 p.

Research output: Contribution to journalArticle

The role of Helicobacter pylori LPS in the pathogenesis of H. pylori-related gastropathy

Jirillo, E., Pece, S., Pellegrino, N. M., Di Leo, A., Russo, F., Linsalata, M., Messa, C., Amati, L., Caradonna, L., Moran, A. P. & Caccavo, D., 1999, In : Innate Immunity. 5, 4, p. 222-226 5 p.

Research output: Contribution to journalArticle

The role of Helicobacter pylori LPS in the pathogenesis of H. pylori-related gastropathy

Jirillo, E., Pece, S., Pellegrino, N. M., Di Leo, A., Russo, F., Linsalata, M., Messa, C., Amati, L., Caradonna, L., Moran, A. P. & Caccavo, D., 1999, In : Journal of Endotoxin Research. 5, 4, p. 222-226 5 p.

Research output: Contribution to journalArticle

1998

Spontaneous and fas-induced apoptotic cell death in aged neutrophils

Tortorella, C., Piazzolla, G., Spaccavento, F., Pece, S., Jirillo, E. & Antonaci, S., 1998, In : Journal of Clinical Immunology. 18, 5, p. 321-329 9 p.

Research output: Contribution to journalArticle

The pathogenesis of fever and its therapeutic implications

Pece, S., Giuliani, G., Caccavo, D., Antonaci, S. & Jirillo, E., 1998, In : Medical Science Research. 26, 1, p. 3-7 5 p.

Research output: Contribution to journalArticle