• 313 Citations
  • 9 h-Index
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Fingerprint Dive into the research topics where Sara Iachettini is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
G-Quadruplexes Medicine & Life Sciences
Telomere Medicine & Life Sciences
Perylene Medicine & Life Sciences
Ligands Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Myotonic Dystrophy Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Pharmacology Medicine & Life Sciences

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Research Output 2010 2019

  • 313 Citations
  • 9 h-Index
  • 18 Article
1 Citation (Scopus)

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

Amato, J., Cerofolini, L., Brancaccio, D., Giuntini, S., Iaccarino, N., Zizza, P., Iachettini, S., Biroccio, A., Novellino, E., Rosato, A., Fragai, M., Luchinat, C., Randazzo, A. & Pagano, B., Jan 1 2019, In : Nucleic Acids Research. 47, 18, p. 9950-9966 17 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Tailoring a lead-like compound targeting multiple G-quadruplex structures

Amato, J., Platella, C., Iachettini, S., Zizza, P., Musumeci, D., Cosconati, S., Pagano, A., Novellino, E., Biroccio, A., Randazzo, A., Pagano, B. & Montesarchio, D., Feb 1 2019, In : European Journal of Medicinal Chemistry. 163, p. 295-306 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

Iachettini, S., Trisciuoglio, D., Rotili, D., Lucidi, A., Salvati, E., Zizza, P., Di Leo, L., Del Bufalo, D., Ciriolo, M. R., Leonetti, C., Steegborn, C., Mai, A., Rizzo, A. & Biroccio, A., Oct 1 2018, In : Cell Death and Disease. 9, 10, 996.

Research output: Contribution to journalArticle

Cell Death
AMP-Activated Protein Kinases
11 Citations (Scopus)
Myotonic Dystrophy
insulin resistance
skeletal muscle
Insulin Resistance
11 Citations (Scopus)

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage

Rizzo, A., Iachettini, S., Salvati, E., Zizza, P., Maresca, C., D'Angelo, C., Benarroch-Popivker, D., Capolupo, A., Gaudio, F. D., Cosconati, S., Maro, S. D., Merlino, F., Novellino, E., Amoreo, C. A., Mottolese, M., Sperduti, I., Gilson, E. & Biroccio, A., Feb 28 2017, In : Nucleic Acids Research. 45, 4, p. 1820-1834 15 p.

Research output: Contribution to journalArticle

Telomere-Binding Proteins
DNA Damage
Protein Stability