• 376 Citations
  • 6 h-Index
20102018
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Research Output 2010 2018

  • 376 Citations
  • 6 h-Index
  • 7 Article
2018
6 Citations (Scopus)

Insc:LGN tetramers promote asymmetric divisions of mammary stem cells

Culurgioni, S., Mari, S., Bonetti, P., Gallini, S., Bonetto, G., Brennich, M., Round, A., Nicassio, F. & Mapelli, M., Dec 1 2018, In : Nature Communications. 9, 1, 1025.

Research output: Contribution to journalArticle

Asymmetric Cell Division
stem cells
Stem cells
division
Breast
2014
37 Citations (Scopus)

Structural and functional framework for the autoinhibition of nedd4-family ubiquitin ligases

Mari, S., Ruetalo, N., Maspero, E., Stoffregen, M. C., Pasqualato, S., Polo, S. & Wiesner, S., Nov 4 2014, In : Structure. 22, 11, p. 1639-1649 11 p.

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Cell Surface Receptors
Catalytic Domain
Magnetic Resonance Spectroscopy
38 Citations (Scopus)

Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity

Persaud, A., Alberts, P., Mari, S., Tong, J., Murchie, R., Maspero, E., Safi, F., Moran, M. F., Polo, S. & Rotin, D., Oct 7 2014, In : Science Signaling. 7, 346, p. ra95

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Fibroblast Growth Factor Receptors
Phosphorylation
Ligases
Ubiquitin
2013
74 Citations (Scopus)

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming

Maspero, E., Valentini, E., Mari, S., Cecatiello, V., Soffientini, P., Pasqualato, S. & Polo, S., Jun 2013, In : Nature Structural and Molecular Biology. 20, 6, p. 696-701 6 p.

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Catalysis
Ubiquitin-Protein Ligases
Ligation
2011
45 Citations (Scopus)

Proteomic snapshot of the EGF-induced ubiquitin network

Argenzio, E., Bange, T., Oldrini, B., Bianchi, F., Peesari, R., Mari, S., Di Fiore, P. P., Mann, M. & Polo, S., 2011, In : Molecular Systems Biology. 7, 462.

Research output: Contribution to journalArticle

Growth Factors
Proteomics
epidermal growth factor
Snapshot
ubiquitin
85 Citations (Scopus)

Structure of the HECT: ubiquitin complex and its role in ubiquitin chain elongation

Maspero, E., Mari, S., Valentini, E., Musacchio, A., Fish, A., Pasqualato, S. & Polo, S., Apr 1 2011, In : EMBO Reports. 12, 4, p. 342-349 8 p.

Research output: Contribution to journalArticle

Ubiquitin
Elongation
Ubiquitination
Substrates
Ligases
2010
91 Citations (Scopus)

TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype

Storci, G., Sansone, P., Mari, S., D'Uva, G., Tavolari, S., Guarnieri, T., Taffurelli, M., Ceccarelli, C., Santini, D., Chieco, P., Marcu, K. B. & Bonafè, M., Dec 2010, In : Journal of Cellular Physiology. 225, 3, p. 682-691 10 p.

Research output: Contribution to journalArticle

NF-kappa B
Stem cells
Up-Regulation
Stem Cells
Tumor Necrosis Factor-alpha