• 1855 Citations
  • 20 h-Index
19992017
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Fingerprint Dive into the research topics where Sebastiano Pasqualato is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Kinetochores Medicine & Life Sciences
Microtubules Medicine & Life Sciences
Guanosine Triphosphate Medicine & Life Sciences
Proteins Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Histone Demethylases Medicine & Life Sciences
GTP Phosphohydrolases Medicine & Life Sciences
Chromosomes Chemical Compounds

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Research Output 1999 2017

  • 1855 Citations
  • 20 h-Index
  • 26 Article
16 Citations (Scopus)

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration

Sartori, L., Mercurio, C., Amigoni, F., Cappa, A., Fagá, G., Fattori, R., Legnaghi, E., Ciossani, G., Mattevi, A., Meroni, G., Moretti, L., Cecatiello, V., Pasqualato, S., Romussi, A., Thaler, F., Trifiró, P., Villa, M., Vultaggio, S., Botrugno, O. A., Dessanti, P. & 6 others, Minucci, S., Zagarrí, E., Carettoni, D., Iuzzolino, L., Varasi, M. & Vianello, P., Mar 9 2017, In : Journal of Medicinal Chemistry. 60, 5, p. 1673-1692 20 p.

Research output: Contribution to journalArticle

Histone Demethylases
Pyrroles
Inhibitory Concentration 50
Lysine
Enzymes
16 Citations (Scopus)

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship

Vianello, P., Sartori, L., Amigoni, F., Cappa, A., Fagá, G., Fattori, R., Legnaghi, E., Ciossani, G., Mattevi, A., Meroni, G., Moretti, L., Cecatiello, V., Pasqualato, S., Romussi, A., Thaler, F., Trifiró, P., Villa, M., Botrugno, O. A., Dessanti, P., Minucci, S. & 4 others, Vultaggio, S., Zagarrí, E., Varasi, M. & Mercurio, C., Mar 9 2017, In : Journal of Medicinal Chemistry. 60, 5, p. 1693-1715 23 p.

Research output: Contribution to journalArticle

Histone Demethylases
Pyrroles
Drug Design
Structure-Activity Relationship
Inhibitory Concentration 50

Erratum: Fast native-SAD phasing for routine macromolecular structure determination (Nature Methods (2015) 12 (131-133))

Weinert, T., Olieric, V., Waltersperger, S., Panepucci, E., Chen, L., Zhang, H., Zhou, D., Rose, J., Ebihara, A., Kuramitsu, S., Li, D., Howe, N., Schnapp, G., Pautsch, A., Bargsten, K., Prota, A. E., Surana, P., Kottur, J., Nair, D. T., Basilico, F. & 8 others, Cecatiello, V., Pasqualato, S., Boland, A., Weichenrieder, O., Wang, B. C., Steinmetz, M. O., Caffrey, M. & Wang, M., Jun 30 2015, In : Nature Methods. 12, 7, p. 692 1 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Fast native-SAD phasing for routine macromolecular structure determination

Weinert, T., Olieric, V., Waltersperger, S., Panepucci, E., Chen, L., Zhang, H., Zhou, D., Rose, J., Ebihara, A., Kuramitsu, S., Li, D., Howe, N., Schnapp, G., Pautsch, A., Bargsten, K., Prota, A. E., Surana, P., Kottur, J., Nair, D. T., Basilico, F. & 8 others, Cecatiello, V., Pasqualato, S., Boland, A., Weichenrieder, O., Wang, B. C., Steinmetz, M. O., Caffrey, M. & Wang, M., Jan 1 2015, In : Nature Methods. 12, 2, p. 131-133 3 p.

Research output: Contribution to journalArticle

Crystallography
Synchrotrons
Membrane Proteins
Diffraction
Single crystals
6 Citations (Scopus)

Purification and characterization of a DNA-binding recombinant PREP1: PBX1 complex

Mathiasen, L., Bruckmann, C., Pasqualato, S. & Blasi, F., Apr 9 2015, In : PLoS One. 10, 4, e0125789.

Research output: Contribution to journalArticle

Recombinant DNA
Purification
DNA
Glutathione Transferase
glutathione transferase