Research Output per year
Research Output 1998 2018
- 1330 Citations
- 17 h-Index
- 41 Article
Emerging Pharmacologic Targets in Cerebral Cavernous Malformation and Potential Strategies to Alter the Natural History of a Difficult Disease: A Review
Chohan, M. O., Marchiò, S., Morrison, L. A., Sidman, R. L., Cavenee, W. K., Dejana, E., Yonas, H., Pasqualini, R. & Arap, W., Jan 1 2018, (Accepted/In press) In : JAMA Neurology.Research output: Contribution to journal › Article
Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: Preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates
Staquicini, D. I., D'Angelo, S., Ferrara, F., Karjalainen, K., Sharma, G., Smith, T. L., Tarleton, C. A., Jaalouk, D. E., Kuniyasu, A., Baze, W. B., Chaffee, B. K., Hanley, P. W., Barnhart, K. F., Koivunen, E., Marchiò, S., Sidman, R. L., Cortes, J. E., Kantarjian, H. M., Arap, W. & Pasqualini, R., May 22 2018, In : Pharmacogenomics Journal. 18, 3, p. 436-443 8 p.Research output: Contribution to journal › Article
Autoantibodies against the cell surface-Associated chaperone GRP78 stimulate tumor growth via tissue factor
Al-Hashimi, A. A., Lebeau, P., Majeed, F., Polena, E., Lhotak, Š., Collins, C. A. F., Pinthus, J. H., Gonzalez-Gronow, M., Hoogenes, J., Pizzo, S. V., Crowther, M., Kapoor, A., Rak, J., Gyulay, G., D'Angelo, S., Marchiò, S., Pasqualini, R., Arap, W., Shayegan, B. & Austin, R. C., Jan 1 2017, In : Journal of Biological Chemistry. 292, 51, p. 21180-21192 13 p.Research output: Contribution to journal › Article
BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation
Lewis, V. O., Devarajan, E., Cardó-Vila, M., Thomas, D. G., Kleinerman, E. S., Marchiò, S., Sidman, R. L., Pasqualini, R. & Arap, W., Jul 25 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 30, p. 8065-8070 6 p.Research output: Contribution to journal › Article
Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates.
Staquicini, D. I., D'Angelo, S., Ferrara, F., Karjalainen, K., Sharma, G., Smith, T. L., Tarleton, C. A., Jaalouk, D. E., Kuniyasu, A., Baze, W. B., Chaffee, B. K., Hanley, P. W., Barnhart, K. F., Koivunen, E., Marchio, S., Sidman, R. L., Cortes, J. E., Kantarjian, H. M., Arap, W. & Pasqualini, R., Dec 1 2017, In : Pharmacogenomics Journal.Research output: Contribution to journal › Article
BCAM and LAMA5 mediate the recognition between tumor cells and the endothelium in the metastatic spreading of KRAS-mutant colorectal cancer
Bartolini, A., Cardaci, S., Lamba, S. E., Oddo, D., Marchiò, C., Cassoni, P., Amoreo, C. A., Corti, G., Testori, A., Bussolino, F., Pasqualini, R., Arap, W., Corà, D., Di Nicolantonio, F. & Marchiò, S., Oct 1 2016, In : Clinical Cancer Research. 22, 19, p. 4923-4933 11 p.Research output: Contribution to journal › Article
BCAM and LAMA5 mediate the recognition between tumor cells and the endothelium in the metastatic spreading of KRAS-mutant colorectal cancer
Bartolini, A., Cardaci, S., Lamba, S., Oddo, D., Marchiò, C., Cassoni, P., Amoreo, C. A., Corti, G., Testori, A., Bussolino, F., Pasqualini, R., Arap, W., Corà, D., Di Nicolantonio, F. & Marchiò, S., Oct 1 2016, In : Clinical Cancer Research. 22, 19, p. 4923-4933 11 p.Research output: Contribution to journal › Article
Brain endothelial cell-targeted gene therapy of neurovascular disorders
Marchiò, S., Sidman, R. L., Arap, W. & Pasqualini, R., Jun 1 2016, In : EMBO Molecular Medicine. 8, 6, p. 592-594 3 p.Research output: Contribution to journal › Article
Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity
Cardó-Vila, M., Marchiò, S., Sato, M., Staquicini, F. I., Smith, T. L., Bronk, J. K., Yin, G., Zurita, A. J., Sun, M., Behrens, C., Sidman, R. L., Lee, J. J., Hong, W. K., Wistuba, I. I., Arap, W. & Pasqualini, R., Aug 1 2016, In : American Journal of Pathology. 186, 8, p. 2162-2170 9 p.Research output: Contribution to journal › Article
Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors
Dondossola, E., Dobroff, A. S., Marchiò, S., Cardó-Vila, M., Hosoya, H., Libutti, S. K., Corti, A., Sidman, R. L., Arap, W. & Pasqualini, R., Feb 23 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 8, p. 2223-2228 6 p.Research output: Contribution to journal › Article
Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors
Dondossola, E., Dobroff, A. S., Marchiò, S., Cardó-Vila, M., Hosoya, H., Libutti, S. K., Corti, A., Sidman, R. L., Arap, W. & Pasqualini, R., Feb 23 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 8, p. 2223-2228 6 p.Research output: Contribution to journal › Article
Targeted molecular-genetic imaging and liganddirected therapy in aggressive variant prostate cancer
Ferrara, F., Staquicini, D. I., Driessen, W. H. P., D'Angelo, S., Dobroff, A. S., Barry, M., Lomo, L. C., Staquicini, F. I., Cardó-Vila, M., Soghomonyan, S., Alauddin, M. M., Flores, L. G., Arap, M. A., Lauer, R. C., Mathew, P., Efstathiou, E., Aparicio, A. M., Troncoso, P., Navone, N. M., Logothetis, C. J. & 5 others, , Nov 8 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 45, p. 12786-12791 6 p.Research output: Contribution to journal › Article
Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes
Dobroff, A. S., D'Angelo, S., Eckhardt, B. L., Ferrara, F., Staquicini, D. I., Cardó-Vila, M., Staquicini, F. I., Nunes, D. N., Kim, K., Driessen, W. H. P., Hajitou, A., Lomo, L. C., Barry, M., Krishnamurthy, S., Sahin, A., Woodward, W. A., Prossnitz, E. R., Anderson, R. L., Dias-Neto, E., Brown-Glaberman, U. A. & 9 others, , Nov 8 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 45, p. 12780-12785 6 p.Research output: Contribution to journal › Article
Ligand-targeted theranostic nanomedicines against cancer
Yao, V. J., D'Angelo, S., Butler, K. S., Theron, C., Smith, T. L., Marchiò, S., Gelovani, J. G., Sidman, R. L., Dobroff, A. S., Brinker, C. J., Bradbury, A. R. M., Arap, W. & Pasqualini, R., Oct 27 2015, (Accepted/In press) In : Journal of Controlled Release.Research output: Contribution to journal › Article
Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion
Cossu, I., Bottoni, G., Loi, M., Emionite, L., Bartolini, A., Di Paolo, D., Brignole, C., Piaggio, F., Perri, P., Sacchi, A., Curnis, F., Gagliani, M. C., Bruno, S., Marini, C., Gori, A., Longhi, R., Murgia, D., Sementa, A. R., Cilli, M., Tacchetti, C. & 5 others, , Nov 1 2015, In : Biomaterials. 68, p. 89-99 11 p.Research output: Contribution to journal › Article
PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3
Salameh, A., Lee, A. K., Cardó-Vila, M., Nunes, D. N., Efstathiou, E., Staquicini, F. I., Dobroff, A. S., Marchiò, S., Navone, N. M., Hosoya, H., Lauer, R. C., Wen, S., Salmeron, C. C., Hoang, A., Newsham, I., Lima, L. A., Carraro, D. M., Oliviero, S., Kolonin, M. G., Sidman, R. L. & 9 others, , Jul 7 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 27, p. 8403-8408 6 p.Research output: Contribution to journal › Article
Synchronous down-modulation of miR-17 family members is an early causative event in the retinal angiogenic switch
Nunes, D. N., Dias-Neto, E., Cardó-Vila, M., Edwards, J. K., Dobroff, A. S., Giordano, R. J., Mandelin, J., Brentani, H. P., Hasselgren, C., Yao, V. J., Marchiò, S., Pereira, C. A. B., Passetti, F., Calin, G. A., Sidman, R. L., Arap, W. & Pasqualini, R., Mar 24 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 12, p. 3770-3775 6 p.Research output: Contribution to journal › Article
The combination of sorafenib and everolimus shows antitumor activity in preclinical models of malignant pleural mesothelioma
Pignochino, Y., Dell'Aglio, C., Inghilleri, S., Zorzetto, M., Basiricò, M., Capozzi, F., Canta, M., Piloni, D., Cemmi, F., Sangiolo, D., Gammaitoni, L., Soster, M., Marchiò, S., Pozzi, E., Morbini, P., Luisetti, M., Aglietta, M., Grignani, G. & Stella, G. M., May 8 2015, In : BMC Cancer. 15, 1, 374.Research output: Contribution to journal › Article
The neuronal pentraxin-2 pathway is an unrecognized target in human neuroblastoma, which also offers prognostic value in patients
Bartolini, A., Di Paolo, D., Noghero, A., Murgia, D., Sementa, A. R., Cilli, M., Pasqualini, R., Arap, W., Bussolino, F., Ponzoni, M., Pastorino, F. & Marchiò, S., Oct 15 2015, In : Cancer Research. 75, 20, p. 4265-4271 7 p.Research output: Contribution to journal › Article
Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer
Parri, M., Pietrovito, L., Grandi, A., Campagnoli, S., De Camilli, E., Bianchini, F., Marchiò, S., Bussolino, F., Jin, B., Sarmientos, P., Grandi, G., Viale, G., Pileri, P., Chiarugi, P. & Grifantini, R., Oct 1 2014, In : Angiogenesis. 17, 4, p. 881-896 16 p.Research output: Contribution to journal › Article
Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models
Peraldo-Neia, C., Cavalloni, G., Soster, M., Gammaitoni, L., Marchiò, S., Sassi, F., Trusolino, L., Bertotti, A., Medico, E., Capussotti, L., Aglietta, M. & Leone, F., Dec 5 2014, In : BMC Cancer. 14, 1, 918.Research output: Contribution to journal › Article
A peptide from the extracellular region of the synaptic protein α Neurexin stimulates angiogenesis and the vascular specific tyrosine kinase Tie2
Graziano, S., Marchiò, S., Bussolino, F. & Arese, M., Mar 22 2013, In : Biochemical and Biophysical Research Communications. 432, 4, p. 574-579 6 p.Research output: Contribution to journal › Article
Emerging lymphae for the fountain of life
Marchiò, S., Astanina, E. & Bussolino, F., Mar 6 2013, In : EMBO Journal. 32, 5, p. 609-611 3 p.Research output: Contribution to journal › Article
Luminescent silica nanoparticles for cancer diagnosis
Arap, W., Pasqualini, R., Montalti, M., Petrizza, L., Prodi, L., Rampazzo, E., Zaccheroni, N. & Marchió, S., Jun 2013, In : Current Medicinal Chemistry. 20, 17, p. 2195-2211 17 p.Research output: Contribution to journal › Article
Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings
Loi, M., Di Paolo, D., Soster, M., Brignole, C., Bartolini, A., Emionite, L., Sun, J., Becherini, P., Curnis, F., Petretto, A., Sani, M., Gori, A., Milanese, M., Gambini, C., Longhi, R., Cilli, M., Allen, T. M., Bussolino, F., Arap, W., Pasqualini, R. & 4 others, , 2013, In : Journal of Controlled Release. 170, 2, p. 233-241 9 p.Research output: Contribution to journal › Article
The combination of sorafenib and everolimus abrogates mTORC1 and mTORC2 upregulation in osteosarcoma preclinical models
Pignochino, Y., Dell'Aglio, C., Basiricò, M., Capozzi, F., Soster, M., Marchiò, S., Bruno, S., Gammaitoni, L., Sangiolo, D., Torchiaro, E., D'Ambrosio, L., Fagioli, F., Ferrari, S., Alberghini, M., Picci, P., Aglietta, M. & Grignani, G., Apr 15 2013, In : Clinical Cancer Research. 19, 8, p. 2117-2131 15 p.Research output: Contribution to journal › Article
The V1/V2 loop of HIV-1 gp120 is necessary for Tat binding and consequent modulation of virus entry
Cardaci, S., Soster, M., Bussolino, F. & Marchiò, S., Sep 17 2013, In : FEBS Letters. 587, 18, p. 2943-2951 9 p.Research output: Contribution to journal › Article
A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6
Marchiò, S., Soster, M., Cardaci, S., Muratore, A., Bartolini, A., Barone, V., Ribero, D., Monti, M., Bovino, P., Sun, J., Giavazzi, R., Asioli, S., Cassoni, P., Capussotti, L., Pucci, P., Bugatti, A., Rusnati, M., Pasqualini, R., Arap, W. & Bussolino, F., Nov 2012, In : EMBO Molecular Medicine. 4, 11, p. 1156-1175 20 p.Research output: Contribution to journal › Article
Antitumor activity of Src inhibitor saracatinib (AZD-0530) in preclinical models of biliary tract carcinomas
Cavalloni, G., Peraldo-Neia, C., Sarotto, I., Gammaitoni, L., Migliardi, G., Soster, M., Marchiò, S., Aglietta, M. & Leone, F., Jul 2012, In : Molecular Cancer Therapeutics. 11, 7, p. 1528-1538 11 p.Research output: Contribution to journal › Article
IL-12-dependent innate immunity arrests endothelial cells in G0-G1 phase by a p21Cip1/Waf1-mediated mechanism
Napione, L., Strasly, M., Meda, C., Mitola, S., Alvaro, M., Doronzo, G., Marchiò, S., Giraudo, E., Primo, L., Arese, M. & Bussolino, F., 2012, In : Angiogenesis. 15, 4, p. 713-725 13 p.Research output: Contribution to journal › Article
SERS active Ag nanoparticles in mesoporous silicon: Detection of organic molecules and peptide-antibody assays
Virga, A., Rivolo, P., Descrovi, E., Chiolerio, A., Digregorio, G., Frascella, F., Soster, M., Bussolino, F., Marchiò, S., Geobaldo, F. & Giorgis, F., Jun 2012, In : Journal of Raman Spectroscopy. 43, 6, p. 730-736 7 p.Research output: Contribution to journal › Article
Targeted dual-color silica nanoparticles provide univocal identification of micrometastases in preclinical models of colorectal cancer
Soster, M., Juris, R., Bonacchi, S., Genovese, D., Montalti, M., Rampazzo, E., Zaccheroni, N., Garagnani, P., Bussolino, F., Prodi, L. & Marchiò, S., 2012, In : International Journal of Nanomedicine. 7, p. 4797-4807 11 p.Research output: Contribution to journal › Article
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma
Loi, M., Marchiò, S., Becherini, P., Di Paolo, D., Soster, M., Curnis, F., Brignole, C., Pagnan, G., Perri, P., Caffa, I., Longhi, R., Nico, B., Bussolino, F., Gambini, C., Ribatti, D., Cilli, M., Arap, W., Pasqualini, R., Allen, T. M., Corti, A. & 2 others, , Jul 2010, In : Journal of Controlled Release. 145, 1, p. 66-73 8 p.Research output: Contribution to journal › Article
Targeting the extracellular signature of metastatic colorectal cancers
Marchi, S., Arap, W. & Pasqualini, R., Mar 2009, In : Expert Opinion on Therapeutic Targets. 13, 3, p. 363-379 17 p.Research output: Contribution to journal › Article
A new computational approach to analyze human protein complexes and predict novel protein interactions
Zanivan, S., Cascone, I., Peyron, C., Molineris, I., Marchio, S., Caselle, M. & Bussolino, F., Dec 4 2007, In : Genome Biology. 8, 12, R256.Research output: Contribution to journal › Article
Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein
Marchiò, S., Alfano, M., Primo, L., Gramaglia, D., Butini, L., Gennero, L., De Vivo, E., Arap, W., Giacca, M., Pasqualini, R. & Bussolino, F., Apr 1 2005, In : Blood. 105, 7, p. 2802-2811 10 p.Research output: Contribution to journal › Article
Identification of CD36 molecular features required for its in vitro angiostatic activity
Primo, L., Ferrandi, C., Roca, C., Marchio, S., Di Blasio, L., Alessio, M. & Bussolino, F., Oct 2005, In : FASEB Journal. 19, 12, p. 1713-1715 3 p.Research output: Contribution to journal › Article
Aminopeptidase A is a functional target in angiogenic blood vessels
Marchiò, S., Lahdenranta, J., Schlingemann, R. O., Valdembri, D., Wesseling, P., Arap, M. A., Hajitou, A., Ozawa, M. G., Trepel, M., Giordano, R. J., Nanus, D. M., Dijkman, H. B. P. M., Oosterwijk, E., Sidman, R. L., Cooper, M. D., Bussolino, F., Pasqualini, R. & Arap, W., Feb 2004, In : Cancer Cell. 5, 2, p. 151-162 12 p.Research output: Contribution to journal › Article
c-fos-Induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro
Marconcini, L., Marchio, S., Morbidelli, L., Cartocci, E., Albini, A., Ziche, M., Bussolino, F. & Oliviero, S., Aug 17 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 17, p. 9671-9676 6 p.Research output: Contribution to journal › Article
Vascular endothelial growth factor-C stimulates the migration and proliferation of Kaposi's sarcoma cells
Marchiò, S., Primo, L., Pagano, M., Palestro, G., Albini, A., Veikkola, T., Cascone, I., Alitalo, K. & Bussolino, F., Sep 24 1999, In : Journal of Biological Chemistry. 274, 39, p. 27617-27622 6 p.Research output: Contribution to journal › Article
Overexpression of the RON gene in human breast carcinoma
Maggiora, P., Marchio', S., Stella, M. C., Giai, M., Belfiore, A., De Bortoli, M., Di Renzo, M. F., Costantino, A., Sismondi, P. & Comoglio, P. M., Jun 4 1998, In : Oncogene. 16, 22, p. 2927-2933 7 p.Research output: Contribution to journal › Article