Research output per year

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Research Output


Acid sensing ion channel 2: A new potential player in the pathophysiology of multiple sclerosis

Fazia, T., Pastorino, R., Notartomaso, S., Busceti, C., Imbriglio, T., Cannella, M., Gentilini, D., Morani, G., Ticca, A., Bitti, P., Berzuini, C., Dalmay, T., Battaglia, G. & Bernardinelli, L., May 2019, In : European Journal of Neuroscience. 49, 10, p. 1233-1243 11 p.

Research output: Contribution to journalArticle

Open Access

Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors

Imbriglio, T., Verhaeghe, R., Martinello, K., Pascarelli, M. T., Chece, G., Bucci, D., Notartomaso, S., Quattromani, M., Mascio, G., Scalabrì, F., Simeone, A., Maccari, S., Del Percio, C., Wieloch, T., Fucile, S., Babiloni, C., Battaglia, G., Limatola, C., Nicoletti, F. & Cannella, M., Dec 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 12, p. 14204-14220 17 p.

Research output: Contribution to journalArticle


mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors

Notartomaso, S., Nakao, H., Mascio, G., Scarselli, P., Cannella, M., Zappulla, C., Madonna, M., Motolese, M., Gradini, R., Liberatore, F., Zonta, M., Carmignoto, G., Battaglia, G., Bruno, V., Watanabe, M., Aiba, A. & Nicoletti, F., Dec 1 2018, In : Scientific Reports. 8, 1, 13361.

Research output: Contribution to journalArticle


Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain

Notartomaso, S., Mascio, G., Bernabucci, M., Zappulla, C., Scarselli, P., Cannella, M., Imbriglio, T., Gradini, R., Battaglia, G., Bruno, V. & Nicoletti, F., Jan 1 2017, In : Molecular Pain. 13

Research output: Contribution to journalArticle

Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

Font, J., López-Cano, M., Notartomaso, S., Scarselli, P., Di Pietro, P., Bresolí-Obach, R., Battaglia, G., Malhaire, F., Rovira, X., Catena, J., Giraldo, J., Pin, J. P., Fernández-Dueñas, V., Goudet, C., Nonell, S., Nicoletti, F., Llebaria, A. & Ciruela, F., Apr 11 2017, In : eLife. 6, e23545.

Research output: Contribution to journalArticle


Expression of the K+/Cl- cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors

Notartomaso, S., Mascio, G., Scarselli, P., Martinello, K., Fucile, S., Gradini, R., Bruno, V., Battaglia, G. & Nicoletti, F., Mar 30 2016, (Accepted/In press) In : Neuropharmacology.

Research output: Contribution to journalArticle


N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans

Truini, A., Piroso, S., Pasquale, E., Notartomaso, S., Di Stefano, G., Lattanzi, R., Battaglia, G., Nicoletti, F. & Cruccu, G., Mar 20 2015, (Accepted/In press) In : Molecular Pain. p. 1-5 5 p.

Research output: Contribution to journalArticle

Type-1, but Not Type-5, Metabotropic Glutamate Receptors are Coupled to Polyphosphoinositide Hydrolysis in the Retina

Romano, M. R., Di Menna, L., Scarselli, P., Mascio, G., Madonna, M., Notartomaso, S., Puliti, A., Bruno, V., Battaglia, G. & Nicoletti, F., Dec 23 2015, (Accepted/In press) In : Neurochemical Research. p. 1-9 9 p.

Research output: Contribution to journalArticle


Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice

Fazio, F., Zappulla, C., Notartomaso, S., Busceti, C., Bessede, A., Scarselli, P., Vacca, C., Gargaro, M., Volpi, C., Allegrucci, M., Lionetto, L., Simmaco, M., Belladonna, M. L., Nicoletti, F. & Fallarino, F., 2014, In : Neuropharmacology. 81, p. 237-243 7 p.

Research output: Contribution to journalArticle


Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1

Notartomaso, S., Zappulla, C., Biagioni, F., Cannella, M., Bucci, D., Mascio, G., Scarselli, P., Fazio, F., Weisz, F., Lionetto, L., Simmaco, M., Gradini, R., Battaglia, G., Signore, M., Puliti, A. & Nicoletti, F., Nov 19 2013, In : Molecular Brain. 6, 1, 48.

Research output: Contribution to journalArticle


Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors

Fazio, F., Lionetto, L., Molinaro, G., Bertrand, H. O., Acher, F., Ngomba, R. T., Notartomaso, S., Curini, M., Rosati, O., Scarselli, P., Di Marco, R., Battaglia, G., Bruno, V., Simmaco, M., Pin, J. P., Nicoletti, F. & Goudet, C., May 2012, In : Molecular Pharmacology. 81, 5, p. 643-656 14 p.

Research output: Contribution to journalArticle

N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors

Bernabucci, M., Notartomaso, S., Zappulla, C., Fazio, F., Cannella, M., Motolese, M., Battaglia, G., Bruno, V., Gradini, R. & Nicoletti, F., Oct 23 2012, In : Molecular Pain. 8, 77.

Research output: Contribution to journalArticle


Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation

Fallarino, F., Volpi, C., Fazio, F., Notartomaso, S., Vacca, C., Busceti, C., Bicciato, S., Battaglia, G., Bruno, V., Puccetti, P., Fioretti, M. C., Nicoletti, F., Grohmann, U. & Di Marco, R., Aug 2010, In : Nature Medicine. 16, 8, p. 897-902 6 p.

Research output: Contribution to journalArticle