If you made any changes in Pure these will be visible here soon.

Research Output 1986 2019

Filter
Article
2019

Impact of different stages of intrauterine inflammation on outcome of preterm neonates: Gestational age-dependent and-independent effect

Pietrasanta, C., Pugni, L., Merlo, D., Acaia, B., Consonni, D., Ronchi, A., Ossola, M. W., Ghirardi, B., Bottino, I., Cribiù, F. M., Bosari, S. & Mosca, F., Feb 1 2019, In : PLoS One. 14, 2, e0211484.

Research output: Contribution to journalArticle

Open Access
Chorioamnionitis
gestational age
Gestational Age
neonates
inflammation

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Zadra, G., Ribeiro, C. F., Chetta, P., Ho, Y., Cacciatore, S., Gao, X., Syamala, S., Bango, C., Photopoulos, C., Huang, Y., Tyekucheva, S., Bastos, D. C., Tchaicha, J., Lawney, B., Uo, T., D’Anello, L., Csibi, A., Kalekar, R., Larimer, B., Ellis, L. & 12 others, Butler, L. M., Morrissey, C., McGovern, K., Palombella, V. J., Kutok, J. L., Mahmood, U., Bosari, S., Adams, J., Peluso, S., Dehm, S. M., Plymate, S. R. & Loda, M., Jan 8 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 2, p. 631-640 10 p.

Research output: Contribution to journalArticle

Open Access
Lipogenesis
Castration
Androgen Receptors
Prostatic Neoplasms
Fatty Acid Synthases

OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy

Sciarra, A., Schmidt, S., Pellegrinelli, A., Maggioni, M., Dondossola, D., Pasquier, J., Cigala, C., Tosi, D., Halkic, N., Bulfamante, G., Viale, G., Bosari, S., Balabaud, C., Bioulac-Sage, P. & Sempoux, C., 2019, In : Liver International. 39, 1, p. 158-167

Research output: Contribution to journalArticle

Liver Cell Adenoma
Focal Nodular Hyperplasia
Neoplasms
Magnetic Resonance Imaging
gadolinium ethoxybenzyl DTPA

OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy

Sciarra, A., Schmidt, S., Pellegrinelli, A., Maggioni, M., Dondossola, D., Pasquier, J., Cigala, C., Tosi, D., Halkic, N., Bulfamante, G., Viale, G., Bosari, S., Balabaud, C., Bioulac-Sage, P. & Sempoux, C., 2019, In : Liver International. 39, 1, p. 158-167 10 p.

Research output: Contribution to journalArticle

OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy

Sciarra, A., Schmidt, S., Pellegrinelli, A., Maggioni, M., Dondossola, D., Pasquier, J., Cigala, C., Tosi, D., Halkic, N., Bulfamante, G., Viale, G., Bosari, S., Balabaud, C., Bioulac-Sage, P. & Sempoux, C., Jan 2019, In : Liver International. 39, 1, p. 158-167 10 p.

Research output: Contribution to journalArticle

Liver Cell Adenoma
Focal Nodular Hyperplasia
Neoplasms
Magnetic Resonance Imaging
gadolinium ethoxybenzyl DTPA

OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy

Sciarra, A., Schmidt, S., Pellegrinelli, A., Maggioni, M., Dondossola, D., Pasquier, J., Cigala, C., Tosi, D., Halkic, N., Bulfamante, G., Viale, G., Bosari, S., Balabaud, C., Bioulac-Sage, P. & Sempoux, C., 2019, In : Liver International. 39, 1, p. 158-167 10 p.

Research output: Contribution to journalArticle

Liver Cell Adenoma
Focal Nodular Hyperplasia
Neoplasms
Magnetic Resonance Imaging
Hepatocytes

P65BTK is a novel potential actionable target in KRAS-mutated/EGFR-wild type lung adenocarcinoma

Giordano, F., Vaira, V., Cortinovis, D., Bonomo, S., Goedmakers, J., Brena, F., Cialdella, A., Ianzano, L., Forno, I., Cerrito, M. G., Giovannoni, R., Ferri, G. L., Tasciotti, E., Vicent, S., Damarco, F., Bosari, S., Lavitrano, M. & Grassilli, E., Jun 14 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 260.

Research output: Contribution to journalArticle

Open Access
Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
Standard of Care
Drug Therapy
Neoplasms

Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo

Terrasi, A., Bertolini, I., Martelli, C., Gaudioso, G., Di Cristofori, A., Storaci, A. M., Formica, M., Bosari, S., Caroli, M., Ottobrini, L., Vaccari, T. & Vaira, V., Mar 1 2019, In : EBioMedicine. 41, p. 214-224 11 p.

Research output: Contribution to journalArticle

Open Access
Glioma
Adenosine Triphosphatases
Growth
Deregulation
Molecular Medicine
2018

A novel tool for predicting extracapsular extension during graded partial nerve sparing in radical prostatectomy

Patel, V. R., Sandri, M., Grasso, A. A. C., De Lorenzis, E., Palmisano, F., Albo, G., Coelho, R. F., Mottrie, A., Harvey, T., Kameh, D., Palayapalayam, H., Wiklund, P., Bosari, S., Puliatti, S., Zuccolotto, P., Bianchi, G. & Rocco, B., Mar 1 2018, In : BJU International. 121, 3, p. 373-382 10 p.

Research output: Contribution to journalArticle

Prostatectomy
Logistic Models
ROC Curve
Capsules
Counseling

Appropriateness of oral anticoagulant therapy prescription and its associated factors in hospitalized older people with atrial fibrillation

on behalf of the SIM-AF Collaborators, Sep 1 2018, In : British Journal of Clinical Pharmacology. 84, 9, p. 2010-2019 10 p.

Research output: Contribution to journalArticle

Anticoagulants
Atrial Fibrillation
Prescriptions
Therapeutics
Inappropriate Prescribing
Neoplasm Genes
Testicular Neoplasms
MicroRNAs
Hepatocellular Carcinoma
Stem Cells

Molecular profiling of lung cancer specimens and liquid biopsies using MALDI-TOF mass spectrometry

Bonaparte, E., Pesenti, C., Fontana, L., Falcone, R., Paganini, L., Marzorati, A., Ferrero, S., Nosotti, M., Mendogni, P., Bareggi, C., Sirchia, S. M., Tabano, S., Bosari, S. & Miozzo, M., Jan 12 2018, In : Diagnostic Pathology. 13, 1, 4.

Research output: Contribution to journalArticle

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Lung Neoplasms
Mass Spectrometry
Biopsy
Mutation

MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state

Poli, V., Fagnocchi, L., Fasciani, A., Cherubini, A., Mazzoleni, S., Ferrillo, S., Miluzio, A., Gaudioso, G., Vaira, V., Turdo, A., Giaggianesi, M., Chinnici, A., Lipari, E., Bicciato, S., Bosari, S., Todaro, M. & Zippo, A., Dec 1 2018, In : Nature Communications. 9, 1, 1024.

Research output: Contribution to journalArticle

stem cells
Stem cells
Epigenomics
Tumors
Carcinogenesis

Pathologic Grading of Malignant Pleural Mesothelioma: An Evidence-Based Proposal

Pelosi, G., Papotti, M., Righi, L., Rossi, G., Ferrero, S., Bosari, S., Calabrese, F., Kern, I., Maisonneuve, P., Sonzogni, A., Albini, A., Harari, S., Barbieri, F., Capelletto, E., Catino, A. M., Cavone, D., De Palma, A., Fusco, N., Lunardi, F., Maiorano, E. & 12 others, Marzullo, A., Novello, S., Papanikolaou, N., Pasello, G., Pennella, A., Pezzuto, F., Punzi, A., Prisciandaro, E., Rea, F., Rosso, L., Scattone, A. & Serio, G., Nov 2018, In : Journal of Thoracic Oncology. 13, 11, p. 1750-1761 12 p.

Research output: Contribution to journalArticle

ROC Curve
Area Under Curve
Survival
Confidence Intervals
Malignant Mesothelioma

Pathologic Grading of Malignant Pleural Mesothelioma: An Evidence-Based Proposal

Pelosi, G., Papotti, M., Righi, L., Rossi, G., Ferrero, S., Bosari, S., Calabrese, F., Kern, I., Maisonneuve, P., Sonzogni, A., Albini, A., Harari, S., Barbieri, F., Capelletto, E., Catino, A. M., Cavone, D., De Palma, A., Fusco, N., Lunardi, F., Maiorano, E. & 12 others, Marzullo, A., Novello, S., Papanikolaou, N., Pasello, G., Pennella, A., Pezzuto, F., Punzi, A., Prisciandaro, E., Rea, F., Rosso, L., Scattone, A. & Serio, G., 2018, In : Journal of Thoracic Oncology. 13, 11, p. 1750-1761

Research output: Contribution to journalArticle

ROC Curve
Area Under Curve
Survival
Confidence Intervals
Malignant Mesothelioma

Pathologic Grading of Malignant Pleural Mesothelioma: An Evidence-Based Proposal

Pelosi, G., Papotti, M., Righi, L., Rossi, G., Ferrero, S., Bosari, S., Calabrese, F., Kern, I., Maisonneuve, P., Sonzogni, A., Albini, A., Harari, S., Barbieri, F., Capelletto, E., Catino, A. M., Cavone, D., De Palma, A., Fusco, N., Lunardi, F., Maiorano, E. & 12 others, Marzullo, A., Novello, S., Papanikolaou, N., Pasello, G., Pennella, A., Pezzuto, F., Punzi, A., Prisciandaro, E., Rea, F., Rosso, L., Scattone, A. & Serio, G., 2018, In : Journal of Thoracic Oncology. 13, 11, p. 1750-1761 12 p.

Research output: Contribution to journalArticle

Pathologic Grading of Malignant Pleural Mesothelioma: An Evidence-Based Proposal

Pelosi, G., Papotti, M., Righi, L., Rossi, G., Ferrero, S., Bosari, S., Calabrese, F., Kern, I., Maisonneuve, P., Sonzogni, A., Albini, A., Harari, S., Barbieri, F., Capelletto, E., Catino, A. M., Cavone, D., De Palma, A., Fusco, N., Lunardi, F., Maiorano, E. & 12 others, Marzullo, A., Novello, S., Papanikolaou, N., Pasello, G., Pennella, A., Pezzuto, F., Punzi, A., Prisciandaro, E., Rea, F., Rosso, L., Scattone, A. & Serio, G., 2018, In : Journal of Thoracic Oncology. 13, 11, p. 1750-1761 12 p.

Research output: Contribution to journalArticle

ROC Curve
Area Under Curve
Survival
Confidence Intervals
Malignant Mesothelioma
Microbiota
Dysbiosis
Anti-Bacterial Agents
T-Lymphocytes
Inflammation

Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells

Burrello, C., Garavaglia, F., Cribiù, F. M., Ercoli, G., Lopez, G., Troisi, J., Colucci, A., Guglietta, S., Carloni, S., Guglielmetti, S., Taverniti, V., Nizzoli, G., Bosari, S., Caprioli, F., Rescigno, M. & Facciotti, F., Dec 1 2018, In : Nature Communications. 9, 1, 5184.

Research output: Contribution to journalArticle

transplantation
secretions
T-cells
Interleukin-10
Restoration

Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells

Burrello, C., Garavaglia, F., Cribiù, F. M., Ercoli, G., Lopez, G., Troisi, J., Colucci, A., Guglietta, S., Carloni, S., Guglielmetti, S., Taverniti, V., Nizzoli, G., Bosari, S., Caprioli, F., Rescigno, M. & Facciotti, F., Dec 1 2018, In : Nature Communications. 9, 1

Research output: Contribution to journalArticle

transplantation
secretions
T-cells
Interleukin-10
Restoration

Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells

Burrello, C., Garavaglia, F., Cribiù, F. M., Ercoli, G., Lopez, G., Troisi, J., Colucci, A., Guglietta, S., Carloni, S., Guglielmetti, S., Taverniti, V., Nizzoli, G., Bosari, S., Caprioli, F., Rescigno, M. & Facciotti, F., Dec 5 2018, In : Nature Communications. 9, 1, p. 5184

Research output: Contribution to journalArticle

transplantation
secretions
T-cells
Interleukin-10
Restoration
2017

Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors

Peverelli, E., Giardino, E., Treppiedi, D., Meregalli, M., Belicchi, M., Vaira, V., Corbetta, S., Verdelli, C., Verrua, E., Serban, A. L., Locatelli, M., Carrabba, G., Gaudenzi, G., Malchiodi, E., Cassinelli, L., Lania, A. G., Ferrero, S., Bosari, S., Vitale, G., Torrente, Y. & 2 others, Spada, A. & Mantovani, G., 2017, In : International Journal of Cancer. 140, 8, p. 1870-1880 11 p.

Research output: Contribution to journalArticle

Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors

Peverelli, E., Giardino, E., Treppiedi, D., Meregalli, M., Belicchi, M., Vaira, V., Corbetta, S., Verdelli, C., Verrua, E., Serban, A. L., Locatelli, M., Carrabba, G., Gaudenzi, G., Malchiodi, E., Cassinelli, L., Lania, A. G., Ferrero, S., Bosari, S., Vitale, G., Torrente, Y. & 2 others, Spada, A. & Mantovani, G., 2017, In : International Journal of Cancer. 140, 8, p. 1870-1880 11 p.

Research output: Contribution to journalArticle

Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors

Peverelli, E., Giardino, E., Treppiedi, D., Meregalli, M., Belicchi, M., Vaira, V., Corbetta, S., Verdelli, C., Verrua, E., Serban, A. L., Locatelli, M., Carrabba, G., Gaudenzi, G., Malchiodi, E., Cassinelli, L., Lania, A. G., Ferrero, S., Bosari, S., Vitale, G., Torrente, Y. & 2 others, Spada, A. & Mantovani, G., Apr 15 2017, In : International Journal of Cancer. 140, 8, p. 1870-1880 11 p.

Research output: Contribution to journalArticle

Dopamine Receptors
Pituitary Neoplasms
Stem Cells
Cyclin D3
Cyclin-Dependent Kinase Inhibitor p27

Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors

Peverelli, E., Giardino, E., Treppiedi, D., Meregalli, M., Belicchi, M., Vaira, V., Corbetta, S., Verdelli, C., Verrua, E., Serban, A. L., Locatelli, M., Carrabba, G., Gaudenzi, G., Malchiodi, E., Cassinelli, L., Lania, A. G., Ferrero, S., Bosari, S., Vitale, G., Torrente, Y. & 2 others, Spada, A. & Mantovani, G., Apr 15 2017, In : International Journal of Cancer. 140, 8, p. 1870-1880 11 p.

Research output: Contribution to journalArticle

Dopamine Receptors
Pituitary Neoplasms
Stem Cells
Cyclin D3
Cyclin-Dependent Kinase Inhibitor p27

Extended versus standard pelvic lymphadenectomy during robot-Assisted radical prostatectomy: The role of extended template as an independent predictor of lymph node invasion with comparable morbidity burden

Mistretta, F. A., Boeri, L., Grasso, A. A., Lo Russo, V., Albo, G., De Lorenzis, E., Maggioni, M., Palmisano, F., Dell'Orto, P., Bosari, S. & Rocco, B., Oct 1 2017, In : Minerva Urologica e Nefrologica. 69, 5, p. 475-485 11 p.

Research output: Contribution to journalArticle

Prostatectomy
Lymph Node Excision
Lymph Nodes
Morbidity
Neoplasm Grading
Glioma
Mass Spectrometry
Chromosomes
Mutation
Chromosome Deletion

miR-494-3p is a novel tumor driver of lung carcinogenesis

Faversani, A., Amatori, S., Augello, C., Colombo, F., Porretti, L., Fanelli, M., Ferrero, S., Palleschi, A., Pelicci, P. G., Belloni, E., Ercoli, G., Degrassi, A., Baccarin, M., Altieri, D. C., Vaira, V. & Bosari, S., Jan 31 2017, In : Oncotarget. 8, 5, p. 7231-7247 17 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Carcinogenesis
Lung
Neoplasms
MicroRNAs

miR-494-3p is a novel tumor driver of lung carcinogenesis

Faversani, A., Amatori, S., Augello, C., Colombo, F., Porretti, L., Fanelli, M., Ferrero, S., Palleschi, A., Pelicci, P. G., Belloni, E., Ercoli, G., Degrassi, A., Baccarin, M., Altieri, D. C., Vaira, V. & Bosari, S., 2017, In : Oncotarget. 8, 5, p. 7231-7247 17 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Carcinogenesis
Lung
Neoplasms
MicroRNAs

Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors

Cirello, V., Vaira, V., Grassi, E. S., Vezzoli, V., Ricca, D., Colombo, C., Bosari, S., Vicentini, L., Persani, L., Ferrero, S. & Fugazzola, L., 2017, In : Oncotarget. 8, 6, p. 9752-9766 15 p.

Research output: Contribution to journalArticle

Cellular Spheroids
Thyroid Gland
Catenins
Neoplasms
Thyroid Neoplasms

Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors

Cirello, V., Vaira, V., Grassi, E. S., Vezzoli, V., Ricca, D., Colombo, C., Bosari, S., Vicentini, L., Persani, L., Ferrero, S. & Fugazzola, L., Feb 7 2017, In : Oncotarget. 8, 6, p. 9752-9766 15 p.

Research output: Contribution to journalArticle

Cellular Spheroids
Thyroid Gland
Catenins
Neoplasms
Thyroid Neoplasms

Primary Soft Tissue Lymphomas: Description of Seven Cases and Review of the Literature

Del Gobbo, A., Fiori, S., Ercoli, G., Di Bernardo, A., Parafioriti, A., Fabris, S., Iurlo, A., Neri, A., Bosari, S. & Gianelli, U., 2017, In : Pathology and Oncology Research. p. 281-286 6 p.

Research output: Contribution to journalArticle

Lymphoma
Lymphoma, Large B-Cell, Diffuse
Anaplastic Large-Cell Lymphoma
Follicular Lymphoma
Cytogenetics

Recurrent NAB2–STAT6 gene fusions and oestrogen receptor-α expression in pulmonary adenofibromas

Fusco, N., Guerini-Rocco, E., Augello, C., Terrasi, A., Ercoli, G., Fumagalli, C., Vacirca, D., Braidotti, P., Parafioriti, A., Jaconi, M., Runza, L., Ananthanarayanan, V., Pagni, F., Bosari, S., Barberis, M. & Ferrero, S., May 1 2017, In : Histopathology. 70, 6, p. 906-917 12 p.

Research output: Contribution to journalArticle

Adenofibroma
Gene Fusion
Estrogen Receptors
Lung
Solitary Fibrous Tumors

Recurrent NAB2–STAT6 gene fusions and oestrogen receptor-α expression in pulmonary adenofibromas

Fusco, N., Guerini-Rocco, E., Augello, C., Terrasi, A., Ercoli, G., Fumagalli, C., Vacirca, D., Braidotti, P., Parafioriti, A., Jaconi, M., Runza, L., Ananthanarayanan, V., Pagni, F., Bosari, S., Barberis, M. & Ferrero, S., 2017, In : Histopathology. 70, 6, p. 906-917 12 p.

Research output: Contribution to journalArticle

2016

Analysis of NSCLC tumour heterogeneity, proliferative and 18F-FDG PET indices reveals Ki67 prognostic role in adenocarcinomas

Del Gobbo, A., Pellegrinelli, A., Gaudioso, G., Castellani, M., Zito Marino, F., Franco, R., Palleschi, A., Nosotti, M., Bosari, S., Vaira, V. & Ferrero, S., 2016, In : Histopathology. 68, 5, p. 746-751 6 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Non-Small Cell Lung Carcinoma
Positron-Emission Tomography
Adenocarcinoma
Neoplasms

A neuronal network of mitochondrial dynamics regulates metastasis

Caino, M. C., Seo, J. H., Aguinaldo, A., Wait, E., Bryant, K. G., Kossenkov, A. V., Hayden, J. E., Vaira, V., Morotti, A., Ferrero, S., Bosari, S., Gabrilovich, D. I., Languino, L. R., Cohen, A. R. & Altieri, D. C., Dec 19 2016, In : Nature Communications. 7, 13730.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Mitochondria
mitochondria
metastasis
Tumors

Chorioamnionitis and neonatal outcome in preterm infants: A clinical overview

Pugni, L., Pietrasanta, C., Acaia, B., Merlo, D., Ronchi, A., Ossola, M. W., Bosari, S. & Mosca, F., May 2 2016, In : Journal of Maternal-Fetal and Neonatal Medicine. 29, 9, p. 1525-1529 5 p.

Research output: Contribution to journalArticle

Chorioamnionitis
Premature Infants
Premature Birth
Inflammation
Infection

Dopamine receptor type 2 (DRD2) inhibits migration and invasion of human tumorous pituitary cells through ROCK-mediated cofilin inactivation

Peverelli, E., Giardino, E., Treppiedi, D., Locatelli, M., Vaira, V., Ferrero, S., Bosari, S., Lania, A. G., Spada, A. & Mantovani, G., Oct 28 2016, In : Cancer Letters. 381, 2, p. 279-286 8 p.

Research output: Contribution to journalArticle

Actin Depolymerizing Factors
Dopamine Receptors
Pituitary Neoplasms
Cell Movement
Neoplasms

Dopamine receptor type 2 (DRD2) inhibits migration and invasion of human tumorous pituitary cells through ROCK-mediated cofilin inactivation

Peverelli, E. M., Giardino, E., Treppiedi, D., Locatelli, M., Vaira, V., Ferrero, S., Bosari, S., Lania, A. G. A., Spada, A. M. & Mantovani, G., Oct 28 2016, In : Cancer Letters. 381, 2, p. 279-286 8 p.

Research output: Contribution to journalArticle

Actin Depolymerizing Factors
Dopamine Receptors
Pituitary Neoplasms
Cell Movement
Neoplasms

Epigenetic effects of chromatin remodeling agents on organotypic cultures

Sirchia, S. M., Faversani, A., Rovina, D., Russo, M. V., Paganini, L., Savi, F., Augello, C., Rosso, L., Del Gobbo, A., Tabano, S., Bosari, S. & Miozzo, M., Mar 1 2016, In : Epigenomics. 8, 3, p. 341-358 18 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Epigenomics
Histone Deacetylases
DNA Methylation
Methylation

MGMT-methylated alleles are distributed heterogeneously within glioma samples irrespective of IDH Status and chromosome 10q Deletion

Fontana, L., Tabano, S., Bonaparte, E., Marfia, G., Pesenti, C., Falcone, R., Augello, C., Carlessi, N., Silipigni, R., Guerneri, S., Campanella, R., Caroli, M., Sirchia, S. M., Bosari, S. & Miozzo, M., Aug 1 2016, In : Journal of Neuropathology and Experimental Neurology. 75, 8, p. 791-800 10 p.

Research output: Contribution to journalArticle

Chromosome Deletion
Methyltransferases
Glioma
Alleles
DNA

Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

Chae, Y. C., Vaira, V., Caino, M. C., Tang, H. Y., Seo, J. H., Kossenkov, A. V., Ottobrini, L., Martelli, C., Lucignani, G., Bertolini, I., Locatelli, M., Bryant, K. G., Ghosh, J. C., Lisanti, S., Ku, B., Bosari, S., Languino, L. R., Speicher, D. W. & Altieri, D. C., Aug 8 2016, In : Cancer Cell. 30, 2, p. 257-272 16 p.

Research output: Contribution to journalArticle

Neoplasms
Pyruvate Dehydrogenase Complex
Autophagy
Glycolysis
Glioma

Morphophenotypic changes in human multistep hepatocarcinogenesis with translational implications

Sciarra, A., Di Tommaso, L., Nakano, M., Destro, A., Torzilli, G., Donadon, M., Maggioni, M., Bosari, S., Bulfamante, G., Matsuda, M., Fujii, H., Ichikawa, T., Morisaka, H., Sano, K., Ichikawa, S. & Roncalli, M., 2016, In : Journal of Hepatology. 64, 1, p. 87-93 7 p.

Research output: Contribution to journalArticle

Prevalence of unexpected leiomyosarcoma at myomectomy: A descriptive study

Vercellini, P., Cribiù, F. M., Bosari, S., Scarfone, G., Bolis, G., Aimi, G. & Fedele, L., Feb 1 2016, In : American Journal of Obstetrics and Gynecology. 214, 2, p. 292-294 3 p.

Research output: Contribution to journalArticle

The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis

Seo, J. H., Rivadeneira, D. B., Caino, M. C., Chae, Y. C., Speicher, D. W., Tang, H. Y., Vaira, V., Bosari, S., Palleschi, A., Rampini, P., Kossenkov, A. V., Languino, L. R. & Altieri, D. C., Jul 7 2016, In : PLoS Biology. 14, 7, e1002507.

Research output: Contribution to journalArticle

succinate dehydrogenase (quinone)
peptidases
metastasis
energy metabolism
Energy Metabolism

Therapeutic Potential of Immunoproteasome Inhibition in Duchenne Muscular Dystrophy

Farini, A., Sitzia, C., Cassani, B., Cassinelli, L., Rigoni, R., Colleoni, F., Fusco, N., Gatti, S., Bella, P., Villa, C., Napolitano, F., Maiavacca, R., Bosari, S., Villa, A. & Torrente, Y., Sep 27 2016, (Accepted/In press) In : Molecular Therapy.

Research output: Contribution to journalArticle

Duchenne Muscular Dystrophy
Proteasome Endopeptidase Complex
Dystrophin
T-Lymphocytes
Antigen Presentation

Therapeutic Potential of Immunoproteasome Inhibition in Duchenne Muscular Dystrophy

Farini, A., Sitzia, C., Cassani, B., Cassinelli, L., Rigoni, R., Colleoni, F., Fusco, N., Gatti, S., Bella, P., Villa, C., Napolitano, F., Maiavacca, R., Bosari, S., Villa, A. & Torrente, Y., Sep 27 2016, (Accepted/In press) In : Molecular Therapy.

Research output: Contribution to journalArticle

Duchenne Muscular Dystrophy
Proteasome Endopeptidase Complex
Dystrophin
T-Lymphocytes
Antigen Presentation

Therapeutic Potential of Immunoproteasome Inhibition in Duchenne Muscular Dystrophy

Farini, A., Sitzia, C., Cassani, B., Cassinelli, L., Rigoni, R., Colleoni, F., Fusco, N., Gatti, S., Bella, P., Villa, C., Napolitano, F., Maiavacca, R., Bosari, S., Villa, A. & Torrente, Y., 2016, In : Molecular Therapy. 24, 11, p. 1898-1912 15 p.

Research output: Contribution to journalArticle

Duchenne Muscular Dystrophy
Proteasome Endopeptidase Complex
Dystrophin
T-Lymphocytes
Antigen Presentation

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells

de Simone, M., Arrigoni, A., Rossetti, G., Gruarin, P., Ranzani, V., Politano, C., Bonnal, R. J. P., Provasi, E., Sarnicola, M. L., Panzeri, I., Moro, M., Crosti, M., Mazzara, S., Vaira, V., Bosari, S., Palleschi, A., Santambrogio, L., Bovo, G., Zucchini, N., Totis, M. & 11 others, Gianotti, L., Cesana, G., Perego, R. A., Maroni, N., Pisani Ceretti, A., Opocher, E., De Francesco, R., Geginat, J., Stunnenberg, H. G., Abrignani, S. & Pagani, M., Nov 15 2016, In : Immunity. 45, 5, p. 1135-1147 13 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Lymphocytes
Neoplasms
Transcriptome
Tumor-Infiltrating Lymphocytes
2015

Adaptive mitochondrial reprogramming and resistance to PI3K therapy

Ghosh, J. C., Siegelin, M. D., Vaira, V., Faversani, A., Tavecchio, M., Chae, Y. C., Lisanti, S., Rampini, P., Giroda, M., Caino, M. C., Seo, J. H., Kossenkov, A. V., Michalek, R. D., Schultz, D. C., Bosari, S., Languino, L. R. & Altieri, D. C., Mar 1 2015, In : Journal of the National Cancer Institute. 107, 3, dju502.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Glioblastoma
Energy Metabolism
Therapeutics
Survival