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2019

Expression of the double-stranded RNA-dependent kinase PKR influences osteosarcoma attachment independent growth, migration, and invasion

Piazzi, M., Bavelloni, A., Greco, S., Focaccia, E., Orsini, A., Benini, S., Gambarotti, M., Faenza, I. & Blalock, W. L., Jun 25 2019, In : Journal of Cellular Physiology. 235, 2, p. 1103-1119 17 p.

Research output: Contribution to journalArticle

Unlocking bone for proteomic analysis and FISH

Mueller, C., Gambarotti, M., Benini, S., Picci, P., Righi, A., Stevanin, M., Hombach-Klonisch, S., Henderson, D., Liotta, L. & Espina, V., May 2019, In : Laboratory Investigation. 99, 5, p. 708-721 14 p.

Research output: Contribution to journalArticle

2018

Detection of circulating tumor cells in liquid biopsy from Ewing sarcoma patients

Benini, S., Gamberi, G., Cocchi, S., Garbetta, J., Alberti, L., Righi, A., Gambarotti, M., Picci, P. & Ferrari, S., Jan 9 2018, In : Cancer Management and Research. 10, p. 49-60 12 p.

Research output: Contribution to journalArticle

miR‑494.3p expression in synovial sarcoma: Role of CXCR4 as a potential target gene

Pazzaglia, L., Pollino, S., Vitale, M., Bientinesi, E., Benini, S., Ferrari, C., Palmerini, E., Gambarotti, M., Picci, P. & Benassi, M. S., Nov 6 2018, In : International Journal of Oncology. 54, 1, p. 361-369 9 p.

Research output: Contribution to journalArticle

Precision diagnostics of Ewing's sarcoma by liquid biopsy: circulating EWS-FLI1 fusion transcripts

Allegretti, M., Casini, B., Mandoj, C., Benini, S., Alberti, L., Novello, M., Melucci, E., Conti, L., Covello, R., Pescarmona, E., Milano, G. M., Annovazzi, A., Anelli, V., Ferraresi, V., Biagini, R. & Giacomini, P., Jun 1 2018, In : Therapeutic Advances in Medical Oncology. 10, p. 1-9 9 p.

Research output: Contribution to journalArticle

Precision diagnostics of Ewing’s sarcoma by liquid biopsy: circulating EWS-FLI1 fusion transcripts

Allegretti, M., Casini, B., Mandoj, C., Benini, S., Alberti, L., Novello, M., Melucci, E., Conti, L., Covello, R., Pescarmona, E., Milano, G. M., Annovazzi, A., Anelli, V., Ferraresi, V., Biagini, R. & Giacomini, P., 2018, In : Therapeutic Advances in Medical Oncology. 10, 9 p.

Research output: Contribution to journalArticle

Utility of STAT 6 and 13q14 deletion in the classification of the benign spindle cell stromal tumors of the breast

Magro, G., Angelico, G., Righi, A., Benini, S., Salvatorelli, L. & Palazzo, J., Jun 22 2018, In : Human Pathology. 81, p. 55-64 10 p.

Research output: Contribution to journalArticle

2017

BCOR-CCNB3 Undifferentiated Sarcoma-Does Immunohistochemistry Help in the Identification?

Ludwig, K., Alaggio, R., Zin, A., Peron, M., Guzzardo, V., Benini, S., Righi, A. & Gambarotti, M., Jan 1 2017, In : Pediatric and Developmental Pathology. 20, 4, p. 321-329 9 p.

Research output: Contribution to journalArticle

Fibrocartilaginous mesenchymoma of bone: a single-institution experience with molecular investigations and a review of the literature

Gambarotti, M., Righi, A., Vanel, D., Cocchi, S., Benini, S., Elli, F. M., Mantovani, G., Ruggieri, P., Boriani, S., Donati, D. M., Sbaraglia, M., Dei Tos, A. P. & Picci, P., Jul 1 2017, In : Histopathology. 71, 1, p. 134-142 9 p.

Research output: Contribution to journalArticle

Fibrocartilaginous mesenchymoma of bone: a single-institution experience with molecular investigations and a review of the literature.

Gambarotti, M., Righi, A., Vanel, D., Cocchi, S., Benini, S., Elli, F. M., Mantovani, G., Ruggieri, P., Boriani, S., Donati, D. M., Sbaraglia, M., Dei Tos, A. P. & Picci, P., Feb 26 2017, In : Histopathology. 71, 1, p. 134-142 9 p.

Research output: Contribution to journalArticle

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

Urbini, M., Astolfi, A., Pantaleo, M. A., Serravalle, S., Dei Tos, A. P., Picci, P., Indio, V., Sbaraglia, M., Benini, S., Righi, A., Gambarotti, M., Gronchi, A., Colombo, C., Dagrada, G. P., Pilotti, S., Maestro, R., Polano, M., Saponara, M., Tarantino, G., Pession, A. & 3 others, Biasco, G., Casali, P. G. & Stacchiotti, S., Jul 1 2017, In : Genes Chromosomes and Cancer. 56, 7, p. 582-586 5 p.

Research output: Contribution to journalArticle

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

Urbini, M., Astolfi, A., Pantaleo, M. A., Serravalle, S., Dei Tos, A. P., Picci, P., Indio, V., Sbaraglia, M., Benini, S., Righi, A., Gambarotti, M., Gronchi, A., Colombo, C., Dagrada, G. P., Pilotti, S., Maestro, R., Polano, M., Saponara, M., Tarantino, G., Pession, A. & 3 others, Biasco, G., Casali, P. G. & Stacchiotti, S., 2017, In : Genes Chromosomes and Cancer. 56, 7, p. 582-586 5 p.

Research output: Contribution to journalArticle

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

Urbini, M., Astolfi, A., Pantaleo, M. A., Serravalle, S., Dei Tos, A. P., Picci, P., Indio, V., Sbaraglia, M., Benini, S., Righi, A., Gambarotti, M., Gronchi, A., Colombo, C., Dagrada, G. P., Pilotti, S., Maestro, R., Polano, M., Saponara, M., Tarantino, G., Pession, A. & 3 others, Biasco, G., Casali, P. G. & Stacchiotti, S., Jul 1 2017, In : Genes Chromosomes and Cancer. 56, 7, p. 582-586 5 p.

Research output: Contribution to journalArticle

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma.

Urbini, M., Astolfi, A., Pantaleo, M. A., Serravalle, S., Dei Tos, A. P., Picci, P., Indio, V., Sbaraglia, M., Benini, S., Righi, A., Gambarotti, M., Gronchi, A., Colombo, C., Dagrada, G. P., Pilotti, S., Maestro, R., Polano, M., Saponara, M., Tarantino, G., Pession, A. & 3 others, Biasco, G., Casali, P. G. & Stacchiotti, S., Apr 6 2017, In : Genes Chromosomes and Cancer. 56, 7, p. 582-586 5 p.

Research output: Contribution to journalArticle

Primary extraskeletal myxoid chondrosarcoma of bone: Report of three cases and review of the literature

Finos, L., Righi, A., Frisoni, T., Gambarotti, M., Ghinelli, C., Benini, S., Vanel, D. & Picci, P., Jan 27 2017, (Accepted/In press) In : Pathology Research and Practice. 213, 5, p. 461-466 6 p.

Research output: Contribution to journalArticle

2016

CIC–DUX4 fusion-positive round-cell sarcomas of soft tissue and bone: a single-institution morphological and molecular analysis of seven cases

Gambarotti, M., Benini, S., Gamberi, G., Cocchi, S., Palmerini, E., Sbaraglia, M., Donati, D., Picci, P., Vanel, D., Ferrari, S., Righi, A. & Dei Tos, A. P., Oct 1 2016, In : Histopathology. 69, 4, p. 624-634 11 p.

Research output: Contribution to journalArticle

2015

MDM2 and CDK4 expression in periosteal osteosarcoma

Righi, A., Gambarotti, M., Benini, S., Gamberi, G., Cocchi, S., Picci, P. & Bertoni, F., Apr 1 2015, In : Human Pathology. 46, 4, p. 549-553 5 p.

Research output: Contribution to journalArticle

MDM2 and CDK4 expression in periosteal osteosarcoma

Righi, A., Gambarotti, M., Benini, S., Gamberi, G., Cocchi, S., Picci, P. & Bertoni, F., Apr 1 2015, In : Human Pathology. 46, 4, p. 549-553 5 p.

Research output: Contribution to journalArticle

Sclerosing epithelioid fibrosarcoma of the thigh: report of two cases with synchronous bone metastases

Righi, A., Gambarotti, M., Manfrini, M., Benini, S., Gamberi, G., Cocchi, S., Casadei, R., Picci, P., Vanel, D. & Dei Tos, A. P., Jul 26 2015, In : Virchows Archiv. 467, 3, p. 339-344 6 p.

Research output: Contribution to journalArticle

Small cell osteosarcoma: Clinicopathologic, immunohistochemical, and molecular analysis of 36 cases

Righi, A., Gambarotti, M., Longo, S., Benini, S., Gamberi, G., Cocchi, S., Vanel, D., Picci, P., Bertoni, F., Simoni, A., Franchi, A. & Dei Tos, A. P., Apr 28 2015, In : American Journal of Surgical Pathology. 39, 5, p. 691-699 9 p.

Research output: Contribution to journalArticle

2014

Diagnostic utility of molecular investigation in extraskeletal myxoid chondrosarcoma

Benini, S., Cocchi, S., Gamberi, G., Magagnoli, G., Vogel, D., Ghinelli, C., Righi, A., Picci, P., Alberghini, M. & Gambarotti, M., 2014, In : Journal of Molecular Diagnostics. 16, 3, p. 314-323 10 p.

Research output: Contribution to journalArticle

2011

Molecular diagnosis in ewing family tumors the rizzoli experience-222 consecutive cases in four years

Gamberi, G., Cocchi, S., Benini, S., Magagnoli, G., Morandi, L., Kreshak, J., Gambarotti, M., Picci, P., Zanella, L. & Alberghini, M., May 2011, In : Journal of Molecular Diagnostics. 13, 3, p. 313-324 12 p.

Research output: Contribution to journalArticle

2007

CD99 isoforms dictate opposite functions in tumour malignancy and metastases by activating or repressing c-Src kinase activity

Scotlandi, K., Zuntini, M., Manara, M. C., Sciandra, M., Rocchi, A., Benini, S., Nicoletti, G., Bernard, G., Nanni, P., Lollini, P. L., Bernard, A. & Picci, P., Oct 11 2007, In : Oncogene. 26, 46, p. 6604-6618 15 p.

Research output: Contribution to journalArticle

Primary malignant myoepithelioma of the distal femur: Case report

Alberghini, M., Pasquinelli, G., Zanella, L., Pignatti, G., Benini, S., Bacchini, P. & Bertoni, F., Apr 2007, In : APMIS. 115, 4, p. 376-380 5 p.

Research output: Contribution to journalArticle

2006

CD99 acts as an oncosuppressor in osteosarcoma

Manara, M. C., Bernard, G., Lollini, P. L., Nanni, P., Zuntini, M., Landuzzi, L., Benini, S., Lattanzi, G., Sciandra, M., Serra, M., Colombo, M. P., Bernard, A., Picci, P. & Scotlandi, K., Apr 2006, In : Molecular Biology of the Cell. 17, 4, p. 1910-1921 12 p.

Research output: Contribution to journalArticle

Insulin-like growth factor binding protein 3 as an anticancer molecule in Ewing's sarcoma

Benini, S., Zuntini, M., Manara, M. C., Cohen, P., Nicoletti, G., Nanni, P., Oh, Y., Picci, P. & Scotlandi, K., Sep 1 2006, In : International Journal of Cancer. 119, 5, p. 1039-1046 8 p.

Research output: Contribution to journalArticle

Targeting CD99 in association with doxorubicin: An effective combined treatment for Ewing's sarcoma

Scotlandi, K., Perdichizzi, S., Bernard, G., Nicoletti, G., Nanni, P., Lollini, P. L., Curti, A., Manara, M. C., Benini, S., Bernard, A. & Picci, P., Jan 2006, In : European Journal of Cancer. 42, 1, p. 91-96 6 p.

Research output: Contribution to journalArticle

2005

Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors

Scotlandi, K., Manara, M. C., Nicoletti, G., Lollini, P. L., Lukas, S., Benini, S., Croci, S., Perdichizzi, S., Zambelli, D., Serra, M., García-Echeverría, C., Hofmann, F. & Picci, P., May 1 2005, In : Cancer Research. 65, 9, p. 3868-3876 9 p.

Research output: Contribution to journalArticle

In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type

Benini, S., Perbal, B., Zambelli, D., Colombo, M. P., Manara, M. C., Serra, M., Parenza, M., Martinez, V., Picci, P. & Scotlandi, K., Jun 23 2005, In : Oncogene. 24, 27, p. 4349-4361 13 p.

Research output: Contribution to journalArticle

Prognostic and therapeutic relevance of HER2 expression in osteosarcoma and Ewing's sarcoma

Scotlandi, K., Manara, M. C., Hattinger, C. M., Benini, S., Perdichizzi, S., Pasello, M., Bacci, G., Zanella, L., Bertoni, F., Picci, P. & Serra, M., Jun 2005, In : European Journal of Cancer. 41, 9, p. 1349-1361 13 p.

Research output: Contribution to journalArticle

2004

Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells

Serra, M., Reverter-Branchat, G., Maurici, D., Benini, S., Shen, J. N., Chano, T., Hattinger, C. M., Manara, M. C., Pasello, M., Scotlandi, K. & Picci, P., Jan 2004, In : Annals of Oncology. 15, 1, p. 151-160 10 p.

Research output: Contribution to journalArticle

Contribution of MEK/MAPK and PI3-K signaling pathway to the malignant behavior of Ewing's sarcoma cells: Therapeutic prospects

Benini, S., Manara, M. C., Cerisano, V., Perdichizzi, S., Strammiello, R., Serra, M., Picci, P. & Scotlandi, K., Jan 20 2004, In : International Journal of Cancer. 108, 3, p. 358-366 9 p.

Research output: Contribution to journalArticle

Differentially expressed genes in multidrug resistant

Chano, T., Mori, K., Scotlandi, K., Benini, S., Lapucci, C., Manara, M. C., Serra, M., Picci, P., Okabe, H. & Baldini, N., Jun 2004, In : Oncology Reports. 11, 6, p. 1257-1263 7 p.

Research output: Contribution to journalArticle

Genetic analysis of fibrosarcoma of bone, a rare tumour entity closely related to osteosarcoma and malignant fibrous histiocytoma of bone

Hattinger, C. M., Tarkkanen, M., Benini, S., Pasello, M., Stoico, G., Bacchini, P., Knuutila, S., Scotlandi, K., Picci, P. & Serra, M., 2004, In : European Journal of Cell Biology. 83, 9, p. 483-491 9 p.

Research output: Contribution to journalArticle

Identification of candidate genes involved in the reversal of malignant phenotype of osteosarcoma cells transfected with the liver/bone/kidney alkaline phosphatase gene

Zucchini, C., Bianchini, M., Valvassori, L., Perdichizzi, S., Benini, S., Manara, M. C., Solmi, R., Strippoli, P., Picci, P., Carinci, P. & Scotlandi, K., Apr 2004, In : Bone. 34, 4, p. 672-679 8 p.

Research output: Contribution to journalArticle

Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: Actin and zyxin as key intracellular mediators

Cerisano, V., Aalto, Y., Perdichizzi, S., Bernard, G., Manara, M. C., Benini, S., Cenacchi, G., Preda, P., Lattanzi, G., Nagy, B., Knuutila, S., Colombo, M. P., Bernard, A., Picci, P. & Scotlandi, K., Jul 22 2004, In : Oncogene. 23, 33, p. 5664-5674 11 p.

Research output: Contribution to journalArticle

2003

c-kit Receptor expression in Ewing's sarcoma: Lack of prognostic value but therapeutic targeting opportunities in appropriate conditions

Scotlandi, K., Manara, M. C., Strammiello, R., Landuzzi, L., Benini, S., Perdichizzi, S., Serra, M., Astolfi, A., Nicoletti, G., Lollini, P. L., Bertoni, F., Nanni, P. & Picci, P., May 15 2003, In : Journal of Clinical Oncology. 21, 10, p. 1952-1960 9 p.

Research output: Contribution to journalArticle

Genomic imbalances associated with methotrexaate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques

Hattinger, C. M., Reverter-Branchat, G., Remondini, D., Castellani, G. C., Benini, S., Pasello, M., Manara, M. C., Scotlandi, K., Picci, P. & Serra, M., Sep 1 2003, In : European Journal of Cell Biology. 82, 9, p. 483-493 11 p.

Research output: Contribution to journalArticle

Impact of IGF-I/IGF-IR Circuit on the Angiogenetic Properties of Ewing's Sarcoma Cells

Strammiello, R., Benini, S., Manara, M. C., Perdichizzi, S., Serra, S., Spisni, E., Picci, P. & Scotlandi, K., Nov 2003, In : Hormone and Metabolic Research. 35, 11-12, p. 675-684 10 p.

Research output: Contribution to journalArticle

Value of P-glycoprotein and clinicopathologic factors as the basis for new treatment strategies in high-grade osteosarcoma of the extremities

Serra, M., Scotlandi, K., Reverter-Branchat, G., Ferrari, S., Manara, M. C., Benini, S., Incaprera, M., Bertoni, F., Mercuri, M., Briccoli, A., Bacci, G. & Picci, P., Feb 1 2003, In : Journal of Clinical Oncology. 21, 3, p. 536-542 7 p.

Research output: Contribution to journalArticle

2002

Effectiveness of ecteinascidin-743 against drug-sensitive and -resistant bone tumor cells

Scotlandi, K., Perdichizzi, S., Manara, M. C., Serra, M., Benini, S., Cerisano, V., Strammiello, R., Mercuri, M., Reverter-Branchat, G., Faircloth, G., D'Incalci, M. & Picci, P., Dec 1 2002, In : Clinical Cancer Research. 8, 12, p. 3893-3903 11 p.

Research output: Contribution to journalArticle

Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells

Scotlandi, K., Maini, C., Manara, M. C., Benini, S., Serra, M., Cerisano, V., Strammiello, R., Baldini, N., Lollini, P. L., Nanni, P., Nicoletti, G. & Picci, P., 2002, In : Cancer Gene Therapy. 9, 3, p. 296-307 12 p.

Research output: Contribution to journalArticle

Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells

Scotlandi, K., Avnet, S., Benini, S., Manara, M. C., Serra, M., Cerisano, V., Perdichizzi, S., Lollini, P. L., De Giovanni, C., Landuzzi, L. & Picci, P., Sep 1 2002, In : International Journal of Cancer. 101, 1, p. 11-16 6 p.

Research output: Contribution to journalArticle