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Research Output 2007 2019

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Article
2017

Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumorbearing c26 mice

Gatta, L., Vitiello, L., Gorini, S., Chiandotto, S., Costelli, P., Giammarioli, A. M., Malorni, W., Rosano, G. & Ferraro, E., Jan 1 2017, In : Oncotarget. 8, 69, p. 113938-113956 19 p.

Research output: Contribution to journalArticle

Trimetazidine
Muscle Development
Myoblasts
Cachexia
Stem Cells

Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice

Gatta, L., Vitiello, L., Gorini, S., Chiandotto, S., Costelli, P., Giammarioli, A. M., Malorni, W., Rosano, G. & Ferraro, E., Dec 26 2017, In : Oncotarget. 8, 69, p. 113938-113956 19 p.

Research output: Contribution to journalArticle

Trimetazidine
Muscle Development
Myoblasts
Neoplasms
Cachexia

The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice

Molinari, F., Pin, F., Gorini, S., Chiandotto, S., Pontecorvo, L., Penna, F., Rizzuto, E., Pisu, S., Musarò, A., Costelli, P., Rosano, G. & Ferraro, E., Dec 2017, In : Journal of Cachexia, Sarcopenia and Muscle. 8, 6, p. 954-973 20 p.

Research output: Contribution to journalArticle

Trimetazidine
Cachexia
Skeletal Muscle
Hand Strength
Neoplasms
2015

Improvement of skeletal muscle performance in ageing by the metabolic modulator Trimetazidine

Ferraro, E., Pin, F., Gorini, S., Pontecorvo, L., Ferri, A., Mollace, V., Costelli, P. & Rosano, G., 2015, (Accepted/In press) In : Journal of Cachexia, Sarcopenia and Muscle.

Research output: Contribution to journalArticle

Trimetazidine
Skeletal Muscle
Muscles
Muscle Strength
Myosin Heavy Chains
2014

Microvascular inflammation in atherosclerosis

Vitiello, L., Spoletini, I., Gorini, S., Pontecorvo, L., Ferrari, D., Ferraro, E., Stabile, E., Caprio, M. & La Sala, A., 2014, In : IJC Metabolic and Endocrine. 3, p. 1-7 7 p.

Research output: Contribution to journalArticle

Atherosclerotic Plaques
Microcirculation
Hypercholesterolemia
Atherosclerosis
Leukocytes
2012

Immunoregulation through extracellular nucleotides

Vitiello, L., Gorini, S., Rosano, G. & La Sala, A., Jul 19 2012, In : Blood. 120, 3, p. 511-518 8 p.

Research output: Contribution to journalArticle

Nucleotides
Adenosine Triphosphate
Purinergic P2 Receptors
Lymphocytes
Immune system
2010

ATP secreted by endothelial cells blocks CX 3CL1-elicited natural killer cell chemotaxis and cytotoxicity via P2Y 11 receptor activation

Gorini, S., Callegari, G., Romagnoli, G., Mammi, C., Mavilio, D., Rosano, G., Fini, M., Di Virgilio, F., Gulinelli, S., Falzoni, S., Cavani, A., Ferrari, D. & La Sala, A., Nov 25 2010, In : Blood. 116, 22, p. 4492-4500 9 p.

Research output: Contribution to journalArticle

Endothelial cells
Chemotaxis
Cytotoxicity
Natural Killer Cells
Endothelial Cells
2009

Cholera toxin inhibits IL-12 production and CD8α+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function

La Sala, A., He, J., Laricchia-Robbio, L., Gorini, S., Iwasaki, A., Braun, M., Yap, G. S., Sher, A., Ozato, K. & Kelsall, B., Jun 8 2009, In : Journal of Experimental Medicine. 206, 6, p. 1227-1235 9 p.

Research output: Contribution to journalArticle

Cholera Toxin
Interleukin-12
Dendritic Cells
Cell Differentiation
Interleukins

Cholera toxin inhibits IL-12 production and CD8α+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function (Journal of Experimental Medicine (2009) 206, 6, (1227-1235))

La Sala, A., He, J., Laricchia-Robbio, L., Gorini, S., Iwasaki, A., Braun, M., Yap, G. S., Sher, A., Ozato, K. & Kelsall, B., Jul 6 2009, In : Journal of Experimental Medicine. 206, 7, p. 1635 1 p.

Research output: Contribution to journalArticle

2008

Hydrolysis of extracellular ATP and immune suppression: Humans versus mice [3]

Gorini, S. & La Sala, A., Jan 15 2008, In : Blood. 111, 2, p. 964-965 2 p.

Research output: Contribution to journalArticle

2007

Shaping immune responses through the activation of dendritic cells' P2 receptors

Ferrari, D., Gorini, S., Callegari, G. & la Sala, A., Mar 2007, In : Purinergic Signalling. 3, 1-2, p. 99-107 9 p.

Research output: Contribution to journalArticle

Dendritic Cells
Adaptive Immunity
Peripheral Tolerance
Cell Shape
Histocompatibility Antigens Class II