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Research Output 1986 2019

2019

HER2 Amplification and Anti-EGFR Sensitivity in Advanced Colorectal Cancer

Bregni, G., Sciallero, S. & Sobrero, A., May 1 2019, In : JAMA oncology. 5, 5, p. 605-606 2 p.

Research output: Contribution to journalComment/debate

Maintenance Olaparib for Metastatic Pancreatic Cancer

Puccini, A., Bregni, G. & Sciallero, S., Oct 10 2019, In : The New England journal of medicine. 381, 15, p. 1491-1492 2 p.

Research output: Contribution to journalLetter

2017

Anti-tumoral effects of somatostatin analogs: a lesson from the CLARINET study

Albertelli, M., Nazzari, E., Sciallero, S., Grillo, F., Morbelli, S., De Cian, F., Cittadini, G., Ambrosetti, E., Ciarmiello, A., Ferone, D. & On behalf of the IRCCS Policlinico San Martino, University of Genova Neuroendocrine Tumor Board, Nov 1 2017, In : Journal of Endocrinological Investigation. 40, 11, p. 1265-1269 5 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Somatostatin
Neoplasms
Acromegaly
Octreotide

Functional analysis of a CDKN2A 5’UTR germline variant associated with pancreatic cancer development

Bruno, W., Andreotti, V., Bisio, A., Pastorino, L., Fornarini, G., Sciallero, S., Bianchi-Scarrà, G., Inga, A. & Ghiorzo, P., Dec 1 2017, In : PLoS One. 12, 12, e0189123.

Research output: Contribution to journalArticle

pancreatic neoplasms
Functional analysis
adenocarcinoma
Pancreatic Neoplasms
germ cells

Including Lynch syndrome in personalized prognostication and follow-up of stage II and III colon cancer

Sciallero, S., Battistuzzi, L. & Varesco, L., 2017, In : Annals of Oncology. 28, 10, p. 2620-2621 2 p.

Research output: Contribution to journalArticle

Management of metastatic colorectal cancer patients: Guidelines of the Italian Medical Oncology Association (AIOM)

Salvatore, L., Aprile, G., Arnoldi, E., Aschele, C., Carnaghi, C., Cosimelli, M., Maiello, E., Normanno, N., Sciallero, S., Valvo, F. & Beretta, G. D., Apr 1 2017, In : ESMO Open. 2, 1, e000147.

Research output: Contribution to journalReview article

Medical Oncology
Colorectal Neoplasms
Guidelines
Cytotoxins
Biological Factors

Management of metastatic colorectal cancer patients: guidelines of the Italian Medical Oncology Association (AIOM)

Salvatore, L., Aprile, G., Arnoldi, E., Aschele, C., Carnaghi, C., Cosimelli, M., Maiello, E., Normanno, N., Sciallero, S., Valvo, F. & Beretta, G. D., 2017, In : ESMO Open. 2, 1, p. e000147

Research output: Contribution to journalArticle

Medical Oncology
Colorectal Neoplasms
Guidelines
Cytotoxins
Biological Factors
2015

Assessing generalizability of the findings of sigmoidoscopy screening trials: The case of SCORE trial

Senore, C., Bonelli, L., Sciallero, S., Casella, C., Santarelli, A., Armaroli, P., Zanetti, R. & Segnan, N., Jan 1 2015, In : Journal of the National Cancer Institute. 107, 1, dju385.

Research output: Contribution to journalArticle

Sigmoidoscopy
Colorectal Neoplasms
Mortality
Volunteers
Confidence Intervals

Referral of Ovarian Cancer Patients for Genetic Counselling by Oncologists: Need for Improvement

Ricci, M. T., Sciallero, S., Mammoliti, S., Gismondi, V., Franiuk, M., Bruzzi, P. & Varesco, L., Jul 25 2015, In : Public Health Genomics. 18, 4, p. 225-232 8 p.

Research output: Contribution to journalArticle

Genetic Counseling
Ovarian Neoplasms
Referral and Consultation
Genetic Testing
Medical Oncology
2013

A multi-peptide, dual-adjuvant telomerase vaccine (GX301) is highly immunogenic in patients with prostate and renal cancer

Fenoglio, D., Traverso, P., Parodi, A., Tomasello, L., Negrini, S., Kalli, F., Battaglia, F., Ferrera, F., Sciallero, S., Murdaca, G., Setti, M., Sobrero, A., Boccardo, F., Cittadini, G., Puppo, F., Criscuolo, D., Carmignani, G., Indiveri, F. & Filaci, G., Jun 2013, In : Cancer Immunology, Immunotherapy. 62, 6, p. 1041-1052 12 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Telomerase
Prostatic Neoplasms
Vaccines
imiquimod
2012

CDKN2A is the main susceptibility gene in Italian pancreatic cancer families

Ghiorzo, P., Fornarini, G., Sciallero, S., Battistuzzi, L., Belli, F., Bernard, L., Bonelli, L., Borgonovo, G., Bruno, W., De Cian, F., Decensi, A., Filauro, M., Faravelli, F., Gozza, A., Gargiulo, S., Mariette, F., Nasti, S., Pastorino, L., Queirolo, P., Savarino, V. & 2 others, Varesco, L. & Scarrà, G. B., Mar 2012, In : Journal of Medical Genetics. 49, 3, p. 164-170 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Mutation
Adenocarcinoma
Genes
Germ-Line Mutation

Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy

Ghiorzo, P., Pensotti, V., Fornarini, G., Sciallero, S., Battistuzzi, L., Belli, F., Bonelli, L., Borgonovo, G., Bruno, W., Gozza, A., Gargiulo, S., Mastracci, L., Nasti, S., Palmieri, G., Papadia, F., Pastorino, L., Russo, A., Savarino, V., Varesco, L., Bernard, L. & 1 others, Bianchi Scarrà, G., Mar 2012, In : Familial Cancer. 11, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Pancreatic Neoplasms
Italy
Adenocarcinoma
Genes
2011

Once-only sigmoidoscopy in colorectal cancer screening: Follow-up findings of the italian randomized controlled trial - SCORE

Segnan, N., Armaroli, P., Bonelli, L., Risio, M., Sciallero, S., Zappa, M., Andreoni, B., Arrigoni, A., Bisanti, L., Casella, C., Crosta, C., Falcini, F., Ferrero, F., Giacomin, A., Giuliani, O., Santarelli, A., Visioli, C. B., Zanetti, R., Atkin, W. S. & Senore, C., Sep 7 2011, In : Journal of the National Cancer Institute. 103, 17, p. 1310-1322 13 p.

Research output: Contribution to journalArticle

Sigmoidoscopy
Early Detection of Cancer
Colorectal Neoplasms
Randomized Controlled Trials
Control Groups

Two doses of NGR-hTNF in combination with capecitabine plus oxaliplatin in colorectal cancer patients failing standard therapies

Mammoliti, S., Andretta, V., Bennicelli, E., Caprioni, F., Comandini, D., Fornarini, G., Guglielmi, A., Pessino, A., Sciallero, S., Sobrero, A. F., Mazzola, G., Lambiase, A. & Bordignon, C., 2011, In : Annals of Oncology. 22, 4, p. 973-978 6 p.

Research output: Contribution to journalArticle

oxaliplatin
Colorectal Neoplasms
Disease-Free Survival
Therapeutics
Chills
2009

Editorial: Prostate cancer screening with PSA: New data, old debate

Sciallero, S. & Fornarini, G., Sep 2009, In : Oncology Reviews. 3, 3, p. 133-135 3 p.

Research output: Contribution to journalArticle

Germline MLH1 and MSH2 mutations in Italian pancreatic cancer patients with suspected Lynch syndrome

Gargiulo, S., Torrini, M., Ollila, S., Nasti, S., Pastorino, L., Cusano, R., Bonelli, L., Battistuzzi, L., Mastracci, L., Bruno, W., Savarino, V., Sciallero, S., Borgonovo, G., Nyström, M., Bianchi-Scarrà, G., Mareni, C. & Ghiorzo, P., Dec 2009, In : Familial Cancer. 8, 4, p. 547-553 7 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Pancreatic Neoplasms
DNA Mismatch Repair
Mutation
Neoplasms
2008

First-line single-agent cetuximab in patients with advanced colorectal cancer

Pessino, A., Artale, S., Sciallero, S., Guglielmi, A., Fornarini, G., Andreotti, I. C., Mammoliti, S., Comandini, D., Caprioni, F., Bennicelli, E., Andretta, V., Siena, S. & Sobrero, A., Apr 2008, In : Annals of Oncology. 19, 4, p. 711-716 6 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Epidermal Growth Factor Receptor
Cetuximab
Phase II Clinical Trials
Combination Drug Therapy
2006

History of negative colorectal endoscopy and risk of rectosigmoid neoplasms at screening flexible sigmoidoscopy

Bonelli, L., Sciallero, S., Senore, C., Zappa, M., Aste, H., Andreoni, B., Angioli, D., Ferraris, R., Gasperoni, S., Malfitana, G., Pennazio, M., Atkin, W. & Segnan, N., Mar 2006, In : International Journal of Colorectal Disease. 21, 2, p. 105-113 9 p.

Research output: Contribution to journalArticle

Sigmoidoscopy
Endoscopy
Adenoma
Colorectal Neoplasms
Neoplasms
2005

Adjuvant therapy for colon cancer: 12 months, 9 months, 6 months ... why not 3 months?

Sobrero, A. & Sciallero, S., Apr 2005, In : Annals of Oncology. 16, 4, p. 521-522 2 p.

Research output: Contribution to journalArticle

2004

Predicting proximal advanced neoplasms at screening sigmoidoscopy

Senore, C., Segnan, N., Bonelli, L., Sciallero, S., Pennazio, M., Angioli, D., Crosta, C., Gasperoni, S. & Malfitana, G., Aug 2004, In : Diseases of the Colon and Rectum. 47, 8, p. 1331-1340 10 p.

Research output: Contribution to journalArticle

Sigmoidoscopy
Polyps
Neoplasms
Colorectal Neoplasms
Colonoscopy

Predictive value of rectal bleeding for distal colonic neoplastic lesions in a screened population

Ferraris, R., Senore, C., Fracchia, M., Sciallero, S., Bonelli, L., Atkin, W. S. & Segnan, N., Jan 2004, In : European Journal of Cancer. 40, 2, p. 245-252 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Hemorrhage
Adenoma
Population
Odds Ratio
2003

Interobserver agreement in the histologic diagnosis of colorectal polyps: The experience of the multicenter adenoma colorectal study (SMAC)

Costantini, M., Sciallero, S., Giannini, A., Gatteschi, B., Rinaldi, P., Lanzanova, G., Bonelli, L., Casetti, T., Bertinelli, E., Giuliani, O., Castiglione, G., Mantellini, P., Naldoni, C. & Bruzzi, P., Mar 1 2003, In : Journal of Clinical Epidemiology. 56, 3, p. 209-214 6 p.

Research output: Contribution to journalArticle

Polyps
Adenoma
Carcinoma
Observer Variation
Practice Guidelines
2002

Baseline findings of the Italian multicenter randomized controlled trial of "Once-Only Sigmoidoscopy" - SCORE

Segnan, N., Senore, C., Andreoni, B., Aste, H., Bonelli, L., Crosta, C., Ferraris, R., Gasperoni, S., Penna, A., Risio, M., Rossini, F. P., Sciallero, S., Zappa, M. & Atkin, W. S., Dec 4 2002, In : Journal of the National Cancer Institute. 94, 23, p. 1763-1772 10 p.

Research output: Contribution to journalArticle

Sigmoidoscopy
Randomized Controlled Trials
Colorectal Neoplasms
Adenoma
Colonoscopy

Prevalence of the E1317Q variant of the APC gene in Italian patients with colorectal adenomas

Gismondi, V., Bonelli, L., Sciallero, S., Margiocco, P., Viel, A., Radice, P., Mondini, P., Sala, P., Montera, M. P., Mareni, C., Quaia, M., Fornasarig, M., Gentile, M., Pietro, G., Rossini, P., Arrigoni, A., Meucci, G. M., Bruzzi, P. & Varesco, L., Dec 2002, In : Genetic Testing. 6, 4, p. 313-317 5 p.

Research output: Contribution to journalArticle

APC Genes
Adenoma
Adenomatous Polyps
Germ-Line Mutation
Colorectal Neoplasms
1999

Do patients with rectosigmoid adenomas 5 mm or less in diameter need total colonoscopy?

Sciallero, S., Bonelli, L., Aste, H., Casetti, T., Bertinelli, E., Bartolini, S., Parri, R., Castiglione, G., Mantellini, P., Costantini, M., Naldoni, C. & Bruzzi, P., 1999, In : Gastrointestinal Endoscopy. 50, 3, p. 314-321 8 p.

Research output: Contribution to journalArticle

Colonoscopy
Adenoma
Polyps
Life Expectancy
Patient Care

Gastroesophageal reflux disease: Relationship between clinical and histological features

Aste, H., Bonelli, L., Ferraris, R., Conio, M., Lapertosa, G., Munizzi, F., Sciallero, S., Bruzzi, P., Baracchini, P., Fulcheri, E., D'Onofrio, V., Iaquinto, G., Ravelli, P., Missale, G., Cestari, R., Macrì, G., Salvadori, G., Briglia, R., Podestà, O., Marchi, S. & 8 others, Costa, F., Maltinti, G., Sablich, R., Lacchin, T., Benedetti, G., Lombardo, L., Fracchia, M. & Pera, A., 1999, In : Digestive Diseases and Sciences. 44, 12, p. 2412-2418 7 p.

Research output: Contribution to journalArticle

Gastroesophageal Reflux
Esophagitis
Epithelium
Barrett Esophagus
Endoscopy
1998

Novel germline APC variants in patients with multiple adenomas

Pedemonte, S., Sciallero, S., Gismondi, V., Stagnaro, P., Biticchi, R., Haeouaine, A., Bonelli, L., Nicolo, G., Groden, J., Bruzzi, P., Aste, H. & Varesco, L., 1998, In : Genes Chromosomes and Cancer. 22, 4, p. 257-267 11 p.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Adenoma
Mutation
Polyps
APC Genes
1997

Cytokeratin immunostaining reveals micrometastasis in negative hematoxylin-eosin lymph nodes of resected stage I-II (pT2-pT3) colorectal cancer

Bertoglio, S., Percivale, P., Gambini, C., Dicasa, D., Meszaros, P., Sciallero, S., Bruzzi, P. & Badellino, F., 1997, In : Journal of Chemotherapy. 9, 2, p. 119-120 2 p.

Research output: Contribution to journalArticle

Distal hyperplastic polyps do not predict proximal adenomas: Results from a multicentric study of colorectal adenomas

Sciallero, S., Costantini, M., Bertinelli, E., Castiglione, G., Onofri, P., Aste, H., Casetti, T., Mantellini, P., Bucchi, L., Parri, R., Boni, L., Bonelli, L., Gatteschi, B., Lanzanova, G., Rinaldi, P., Giannini, A., Naldoni, C. & Bruzzi, P., 1997, In : Gastrointestinal Endoscopy. 46, 2, p. 124-130 7 p.

Research output: Contribution to journalArticle

Polyps
Adenoma
Odds Ratio
Colonoscopy
Adenomatous Polyposis Coli
1996

Barrett's esophagus in patients referred for upper gastrointestinal endoscopy

Conio, M., Bonelli, L., Picasso, M., Antonelli, G., Aste, H., Munizzi, F., Sciallero, S., Bruzzi, P., Gocioso, L., Lapertosa, G., Baracchini, P., Fulcheri, E., Ravelli, P., Missale, G., Cestari, R., Picciotto, A., Mele, R., Celle, G., Bovero, E., Cheli, R. & 22 others, Briglia, R., Podesta, O., Rainisio, C., Marenco, G., Ghezzo, L., Asnaghi, G., Ferro, G. F., Lombardo, L., De La Pierre, M., Ferraris, R., Fracchia, M., Babando, G. B., Sablish, R., Lacchin, T., Benedetti, G., Marchi, S., Costa, F., Maltinti, G., D'Onofrio, V., Iaquinto, G., Macri, G. & Salvadori, G., 1996, In : Giornale Italiano di Endoscopia Digestiva. 19, 4, p. 267-273 7 p.

Research output: Contribution to journalArticle

Gastrointestinal Endoscopy
Barrett Esophagus
Esophagitis
Epithelium
Esophagus
1995

A multicenter study of colorectal adenomas. Rationale, objectives, methods and characteristics of the study cohort

Bruzzi, P., Bonelli, L., Costantini, M., Sciallero, S., Boni, L., Aste, H., Gatteschi, B., Naldoni, C., Bucchi, L., Casetti, T., Bertinelli, E., Lanzanova, G., Onofri, P., Parri, R., Rinaldi, P., Castiglione, G., Mantellini, P. & Giannini, A., 1995, In : Tumori. 81, 3, p. 157-163 7 p.

Research output: Contribution to journalArticle

Polyps
Adenoma
Multicenter Studies
Cohort Studies
Endoscopy
1994

Association of APC gene mutations and histological characteristics of colorectal adenomas

De Benedetti, L., Sciallero, S., Gismondi, V., James, R., Bafico, A., Biticchi, R., Masetti, E., Bonelli, L., Heouaine, A., Picasso, M., Groden, J., Robertson, M., Risio, M., Caprilli, R., Bruzzi, P., White, R. L., Aste, H., Santi, L., Varesco, L. & Ferrara, G. B., Jul 1 1994, In : Cancer Research. 54, 13, p. 3553-3556 4 p.

Research output: Contribution to journalArticle

APC Genes
Adenoma
Mutation
Genes
Villous Adenoma

Erratum: Endoscopy (1993) 25 (648)

Sciallero, S., Giaretti, W., Bonelli, L., Geido, E., Rapallo, A., Conio, M., Ravelli, P., Lombardo, L., Briglia, R., Lapertosa, G. & Aste, H., 1994, In : Endoscopy. 26, 3, p. 335 1 p.

Research output: Contribution to journalArticle

Lack of prognostic value of flow cytometric DNA content analysis in colorectal adenocarcinomas

Sciallero, S., Bonelli, L., Geido, E., Lettieri, L., Zeraschi, E., Bruzzi, P., Aste, H. & Giaretti, W., 1994, In : European Journal of Cancer. 30, 4, p. 569 1 p.

Research output: Contribution to journalArticle

LINEE GUIDA PER LA SORVEGLIANZA DI PAZIENTI CON ESOFAGO DI BARRETT

Translated title of the contribution: Guidelines in patients with Barrett's esophagusAste, H., Picasso, M., Bonelli, L., Conio, M., Munizzi, F., Sciallero, S., Bruzzi, P., Gogioso, L., Lapertosa, G., Fulcheri, E., Baracchini, P., Picciotto, A., Mele, R., Celle, G., Lombardo, L., De La Pierre, M., Ferraris, R., Babando, G. B. & Fracchia, M., 1994, In : Giornale Italiano di Endoscopia Digestiva. 17, 4, p. 191-195 5 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Guidelines
Epithelium
Quality of Health Care
Stomach
1993

DNA aneuploidy is an independent factor of poor prognosis in pancreatic and peripancreatic cancer

Sciallero, S., Giaretti, W., Geido, E., Bonelli, L., Zhankui, L., Saccomanno, S., Zeraschi, E. & Pugliese, V., Aug 1993, In : International Journal of Pancreatology. 14, 1, p. 21-28 8 p.

Research output: Contribution to journalArticle

Aneuploidy
Pancreatic Neoplasms
DNA
Common Bile Duct
Neoplasms

DNA content analysis of Barrett's esophagus by flow cytometry

Sciallero, S., Giaretti, W., Bonelli, L., Geido, E., Rapallo, A., Conio, M., Ravelli, P., Lombardo, L., Lapertosa, G. & Aste, H., 1993, In : Endoscopy. 25, 9, p. 648-651 4 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Flow Cytometry
DNA
Aneuploidy
Ploidies

Genetic events in sporadic colorectal adenomas: K-ras and p53 heterozygous mutations are not sufficient for malignant progression

De Benedetti, L., Varesco, L., Pellegata, N. S., Losi, L., Gismondi, V., Casarino, L., Sciallero, S., Bonelli, L., Biticchi, R., Bafico, A., Masetti, E., James, R., Heouaine, A., Ranzani, G. N., Aste, H. & Ferrara, G., 1993, In : Anticancer Research. 13, 3, p. 667-670 4 p.

Research output: Contribution to journalArticle

Adenoma
Mutation
ras Genes
Loss of Heterozygosity
p53 Genes

Genomic PCR-SSCP analysis of the metastasis associated NM23-H1(NME1) gene: A study on colorectal cancer

Bafico, A., Varesco, L., De Benedetti, L., Caligo, M. A., Gismondi, V., Sciallero, S., Aste, H., Ferrara, G. B. & Bevilacqua, G., 1993, In : Anticancer Research. 13, 6 A, p. 2149-2154 6 p.

Research output: Contribution to journalArticle

Single-Stranded Conformational Polymorphism
Colorectal Neoplasms
Exons
Neoplasm Metastasis
Polymerase Chain Reaction

Socioeconomic characteristics, life style, diabetes, family history of cancer and risk of pancreatic cancer

Sciallero, S., Bonelli, L., Saccomanno, S., Conio, M., Bruzzi, P. & Pugliese, V., 1993, In : European Journal of Gastroenterology and Hepatology. 5, 5, p. 367-371 5 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Life Style
Neoplasms
Alcohol Drinking
Coffee
1991

Flow cytometric DNA index in the prognosis of colorectal cancer

Giaretti, W., Danova, M., Geido, E., Mazzini, G., Sciallero, S., Aste, H., Scivetti, P., Riccardi, A., Marsano, B., Merlo, F. & D'Amore, E. S. G., 1991, In : Cancer. 67, 7, p. 1921-1927 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
DNA
Aneuploidy
Diploidy
Paraffin
1989

DNA flow cytometry of endoscopically examined colorectal adenocarcinomas

Giaretti, W., Sciallero, S., Bruno, S., Geido, E., Aste, H., Di Vin ci, A. & d'Amore, E. S. G., 1989, In : Pathology Research and Practice. 185, 5, p. 589-593 5 p.

Research output: Contribution to journalArticle

Flow Cytometry
Adenocarcinoma
DNA
Ploidies
Aneuploidy
1988

DNA flow cytometry of endoscopically examined colorectal adenomas and adenocarcinomas

Giaretti, W., Sciallero, S., Bruno, S., Geido, E., Aste, H. & Di Vinci, A., 1988, In : Cytometry. 9, 3, p. 238-244 7 p.

Research output: Contribution to journalArticle

Flow cytometric DNA ploidy in colorectal adenomas and family history of colorectal cancer

Sciallero, S., Bruno, S., Di Vinci, A., Geido, E., Aste, H. & Gairetti, W., 1988, In : Cancer. 61, 1, p. 114-120 7 p.

Research output: Contribution to journalArticle

Ploidies
Adenoma
Colorectal Neoplasms
Aneuploidy
DNA
1987

Gastric epithelial dysplasia in peptic gastric ulcer

Sciallero, S., Conio, M., Gatteschi, B. & Aste, H., 1987, In : Journal of Experimental and Clinical Cancer Research. 6, 1, p. 39-42 4 p.

Research output: Contribution to journalArticle

Irrigazione periodica e colonscopica in pazienti colostomizzati.

Translated title of the contribution: Periodic irrigation and coloscopy in patients with colostomySciallero, S., Aste, H., Dini, D., Forno, G., Casanova, R. & Grandi, G., Mar 15 1987, In : Minerva Chirurgica. 42, 5, p. 391-394 4 p.

Research output: Contribution to journalArticle

1986

The clinical significance of gastric epithelial dysplasia

Aste, H., Sciallero, S., Pugliese, V. & Gennaro, M., 1986, In : Endoscopy. 18, 5, p. 174-176 3 p.

Research output: Contribution to journalArticle

Stomach
Carcinoma
Biopsy
Stomach Ulcer
Polyps