19992019

Research output per year

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Research Output

2019

Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer

Tacconi, C., Ungaro, F., Correale, C., Arena, V., Massimino, L., Detmar, M., Spinelli, A., Carvello, M., Mazzone, M., Oliveira, A. I., Rubbino, F., Garlatti, V., Spanò, S., Lugli, E., Colombo, F. S., Malesci, A., Peyrin-Biroulet, L., Vetrano, S., Danese, S. & D'Alessio, S., Aug 15 2019, In : Cancer Research. 79, 16, p. 4196-4210 15 p.

Research output: Contribution to journalArticle

Hyaluronan Accelerates Intestinal Mucosal Healing through Interaction with TSG-6

Sammarco, G., Shalaby, M., Elangovan, S., Petti, L., Roda, G., Restelli, S., Arena, V., Ungaro, F., Fiorino, G., Day, A. J., D'Alessio, S. & Vetrano, S., Sep 12 2019, In : Cells. 8, 9

Research output: Contribution to journalArticle

Lymphatic endothelium contributes to colorectal cancer growth via the soluble matrisome component GDF11

Ungaro, F., Colombo, P., Massimino, L., Ugolini, G. S., Correale, C., Rasponi, M., Garlatti, V., Rubbino, F., Tacconi, C., Spaggiari, P., Spinelli, A., Carvello, M., Sacchi, M., Spanò, S., Vetrano, S., Malesci, A., Peyrin-Biroulet, L., Danese, S. & D'Alessio, S., Oct 1 2019, In : International Journal of Cancer. 145, 7, p. 1913-1920 8 p.

Research output: Contribution to journalArticle

mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn's Disease

Ungaro, F., Garlatti, V., Massimino, L., Spinelli, A., Carvello, M., Sacchi, M., Spanò, S., Colasante, G., Valassina, N., Vetrano, S., Malesci, A., Peyrin-Biroulet, L., Danese, S. & D'Alessio, S., Aug 18 2019, In : Cells. 8, 8

Research output: Contribution to journalArticle

NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer

Mikulak, J., Oriolo, F., Bruni, E., Roberto, A., Colombo, F. S., Villa, A., Bosticardo, M., Bortolomai, I., Lo Presti, E., Meraviglia, S., Dieli, F., Vetrano, S., Danese, S., Della Bella, S., Carvello, M. M., Sacchi, M., Cugini, G., Colombo, G., Klinger, M., Spaggiari, P. & 8 others, Roncalli, M., Prinz, I., Ravens, S., di Lorenzo, B., Marcenaro, E., Silva-Santos, B., Spinelli, A. & Mavilio, D., Dec 19 2019, In : JCI insight. 4, 24

Research output: Contribution to journalArticle

TNF-Stimulated Gene-6 Is a Key Regulator in Switching Stemness and Biological Properties of Mesenchymal Stem Cells

Romano, B., Elangovan, S., Erreni, M., Sala, E., Petti, L., Kunderfranco, P., Massimino, L., Restelli, S., Sinha, S., Lucchetti, D., Anselmo, A., Colombo, F. S., Stravalaci, M., Arena, V., D'Alessio, S., Ungaro, F., Inforzato, A., Izzo, A. A., Sgambato, A., Day, A. J. & 1 others, Vetrano, S., Jul 2019, In : Stem Cells. 37, 7, p. 973-987 15 p.

Research output: Contribution to journalArticle

2018

Proceedings of the signature series event of the international society for cellular therapy: “Advancements in cellular therapies and regenerative medicine in digestive diseases,” London, United Kingdom, May 3, 2017

Ciccocioppo, R., Dos Santos, C. C., Baumgart, D. C., Cangemi, G. C., Cardinale, V., Ciacci, C., De Coppi, P., Haldar, D., Klersy, C., Nostro, M. C., Ott, M., Piemonti, L., Tomei, A. A., Uygun, B., Vetrano, S. & Orlando, G., Mar 1 2018, In : Cytotherapy. 20, 3, p. 461-476 16 p.

Research output: Contribution to journalReview article

Protumor steering of cancer inflammation by p50 nf-kb enhances colorectal cancer progression

Porta, C., Ippolito, A., Consonni, F. M., Carraro, L., Celesti, G., Correale, C., Grizzi, F., Pasqualini, F., Tartari, S., Rinaldi, M., Bianchi, P., Balzac, F., Vetrano, S., Turco, E., Hirsch, E., Laghi, L. & Sica, A., May 1 2018, In : Cancer immunology research. 6, 5, p. 578-593 16 p.

Research output: Contribution to journalArticle

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

Morini, R., Filipello, F., Corradini, I., Zerbi, V., Canzi, A., Michalski, B., Erreni, M., Markicevic, M., Starvaggi-Cucuzza, C., Otero, K., Piccio, L., Cignarella, F., Perrucci, F., Tamborini, M., Genua, M., Rajendran, L., Menna, E., Vetrano, S., Fahnestock, M., Paolicelli, R. C. & 1 others, Matteoli, M., May 15 2018, In : Immunity. 48, 5, p. 979-991.e8

Research output: Contribution to journalArticle

2017

Centrally Determined Standardization of Flow Cytometry Methods Reduces Interlaboratory Variation in a Prospective Multicenter Study

Westera, L., Van Viegen, T., Jeyarajah, J., Azad, A., Bilsborough, J., Van Den Brink, G. R., Cremer, J., Danese, S., D'Haens, G., Eckmann, L., Faubion, W., Filice, M., Korf, H., McGovern, D., Panes, J., Salas, A., Sandborn, W. J., Silverberg, M. S., Smith, M. I., Vermeire, S. & 8 others, Vetrano, S., Shackelton, L. M., Stitt, L., Jairath, V., Levesque, B. G., Spencer, D. M., Feagan, B. G. & Casteele, N. V., Nov 2 2017, In : Clinical and Translational Gastroenterology. 8, 11, e126.

Research output: Contribution to journalArticle

MFSD2A Promotes Endothelial Generation of Inflammation-Resolving Lipid Mediators and Reduces Colitis in Mice

Ungaro, F., Tacconi, C., Massimino, L., Corsetto, P. A., Correale, C., Fonteyne, P., Piontini, A., Garzarelli, V., Calcaterra, F., Della Bella, S., Spinelli, A., Carvello, M., Rizzo, A. M., Vetrano, S., Petti, L., Fiorino, G., Furfaro, F., Mavilio, D., Maddipati, K. R., Malesci, A. & 3 others, Peyrin-Biroulet, L., D'Alessio, S. & Danese, S., Nov 1 2017, In : Gastroenterology. 153, 5, p. 1363-1377.e6

Research output: Contribution to journalArticle

Reciprocal influence of B cells and tumor macro and microenvironments in the ApcMin/+ model of colorectal cancer

Mion, F., Vetrano, S., Tonon, S., Valeri, V., Piontini, A., Burocchi, A., Petti, L., Frossi, B., Gulino, A., Tripodo, C., Colombo, M. P. & Pucillo, C. E., Aug 3 2017, In : OncoImmunology. 6, 8, e1336593.

Research output: Contribution to journalArticle

Reciprocal influence of B cells and tumor macro and microenvironments in the ApcMin/+ model of colorectal cancer

Mion, F., Vetrano, S., Tonon, S., Valeri, V., Piontini, A., Burocchi, A., Petti, L., Frossi, B., Gulino, A., Tripodo, C., Colombo, M. P. & Pucillo, C. E., 2017, In : OncoImmunology. 6, 8, e1336593.

Research output: Contribution to journalArticle

2016

Anti-TNF antibodies and autophagy: A hidden nexus for a successful therapeutic response?

Genua, M., Becker, C. & Vetrano, S., Mar 1 2016, In : Journal of Crohn's & colitis. 10, 3, p. 237-238 2 p.

Research output: Contribution to journalArticle

Meet our editorial board member

Vetrano, S., Mar 1 2016, In : Current Drug Targets. 17, 4, p. 375 1 p.

Research output: Contribution to journalArticle

Programming of Intestinal Epithelial Differentiation by IL-33 Derived from Pericryptal Fibroblasts in Response to Systemic Infection

Mahapatro, M., Foersch, S., Hefele, M., He, G. W., Giner-Ventura, E., Mchedlidze, T., Kindermann, M., Vetrano, S., Danese, S., Günther, C., Neurath, M. F., Wirtz, S. & Becker, C., May 24 2016, In : Cell Reports. 15, 8, p. 1743-1756 14 p.

Research output: Contribution to journalArticle

Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation

López-Posadas, R., Becker, C., Günther, C., Tenzer, S., Amann, K., Billmeier, U., Atreya, R., Fiorino, G., Vetrano, S., Danese, S., Ekici, A. B., Wirtz, S., Thonn, V., Watson, A. J. M., Brakebusch, C., Bergö, M., Neurath, M. F. & Atreya, I., Feb 1 2016, In : Journal of Clinical Investigation. 126, 2, p. 611-626 16 p.

Research output: Contribution to journalArticle

2015

Cathelicidins: A Novel Therapy for the Treatment of Intestinal Fibrosis?

Vetrano, S. & Genua, M., Jan 1 2015, In : CMGH Cellular and Molecular Gastroenterology and Hepatology. 1, 1, p. 2-3 2 p.

Research output: Contribution to journalArticle

Meet our editorial board member

Vetrano, S., Aug 1 2015, In : Current Drug Targets. 16, 7, p. 683 1 p.

Research output: Contribution to journalArticle

Mesenchymal Stem Cells in IBD: unMaSCing Their Therapeutic Mechanisms

Scaldaferri, F. & Vetrano, S., Jul 13 2015, In : Digestive Diseases and Sciences. 60, 7, p. 1873-1875 3 p.

Research output: Contribution to journalArticle

Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine

Sala, E., Genua, M., Petti, L., Anselmo, A., Arena, V., Cibella, J., Zanotti, L., D'Alessio, S., Scaldaferri, F., Luca, G., Arato, I., Calafiore, R., Sgambato, A., Rutella, S., Locati, M., Danese, S. & Vetrano, S., Jul 1 2015, In : Gastroenterology. 149, 1, p. 163-176 14 p., 59674.

Research output: Contribution to journalArticle

The urokinase plasminogen activator receptor (uPAR) controls macrophage phagocytosis in intestinal inflammation

Genua, M., D'Alessio, S., Cibella, J., Gandelli, A., Sala, E., Correale, C., Spinelli, A., Arena, V., Malesci, A., Rutella, S., Ploplis, V. A., Vetrano, S. & Danese, S., Apr 1 2015, In : Gut. 64, 4, p. 589-600 12 p.

Research output: Contribution to journalArticle

2014

Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis

Roulis, M., Nikolaou, C., Kotsaki, E., Kaffe, E., Karagianni, N., Koliaraki, V., Salpea, K., Ragoussis, J., Aidinis, V., Martini, E., Becker, C., Herschman, H. R., Vetrano, S., Danese, S. & Kollias, G., Oct 28 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 43, p. E4658-E4667

Research output: Contribution to journalArticle

VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease

D'Alessio, S., Correale, C., Tacconi, C., Gandelli, A., Pietrogrande, G., Vetrano, S., Genua, M., Arena, V., Spinelli, A., Peyrin-Biroulet, L., Fiocchi, C. & Danese, S., Sep 2 2014, In : Journal of Clinical Investigation. 124, 9, p. 3863-3878 16 p.

Research output: Contribution to journalArticle

2013

Bacterial sensor triggering receptor expressed on myeloid cells-2 regulates the mucosal inflammatory response

Correale, C., Genua, M., Vetrano, S., Mazzini, E., Martinoli, C., Spinelli, A., Arena, V., Peyrin-Biroulet, L., Caprioli, F., Passini, N., Panina-Bordignon, P., Repici, A., Malesci, A., Rutella, S., Rescigno, M. & Danese, S., Feb 2013, In : Gastroenterology. 144, 2

Research output: Contribution to journalArticle

Colitis, microbiota, and colon cancer: an infernal triangle.

Vetrano, S. & Danese, S., Feb 2013, In : Gastroenterology. 144, 2, p. 461-463 3 p.

Research output: Contribution to journalArticle

Effect of tumor necrosis factor-a blockade on mucosal addressin cell-adhesion molecule-1 in Crohn's disease

Biancheri, P., Di Sabatino, A., Rovedatti, L., Giuffrida, P., Calarota, S. A., Vetrano, S., Vidali, F., Pasini, A., Danese, S., Corazza, G. R. & MacDonald, T. T., Feb 2013, In : Inflammatory Bowel Diseases. 19, 2, p. 259-264 6 p.

Research output: Contribution to journalArticle

Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease

Iborra, M., Bernuzzi, F., Correale, C., Vetrano, S., Fiorino, G., Beltrán, B., Marabita, F., Locati, M., Spinelli, A., Nos, P., Invernizzi, P. & Danese, S., Aug 2013, In : Clinical and Experimental Immunology. 173, 2, p. 250-258 9 p.

Research output: Contribution to journalArticle

Mesenchymal stromal cells in inflammatory bowel disease: Conspirators within the 'colitogenic niche'?

Danese, S., Rutella, S. & Vetrano, S., Aug 2013, In : Gut. 62, 8, p. 1098-1099 2 p.

Research output: Contribution to journalArticle

Sealing the broken barrier in IBD: intestinal permeability, epithelial cells and junctions.

Fries, W., Belvedere, A. & Vetrano, S., Nov 2013, In : Current Drug Targets. 14, 12, p. 1460-1470 11 p.

Research output: Contribution to journalArticle

2012

Effects of immunosuppression on immune response to pneumococcal vaccine in inflammatory bowel disease: A prospective study

Fiorino, G., Peyrin-Biroulet, L., Naccarato, P., Szabò, H., Sociale, O. R., Vetrano, S., Fries, W., Montanelli, A., Repici, A., Malesci, A. & Danese, S., Jun 2012, In : Inflammatory Bowel Diseases. 18, 6, p. 1042-1047 6 p.

Research output: Contribution to journalArticle

The protein C pathway in intestinal barrier function: Challenging the hemostasis paradigm

D'Alessio, S., Genua, M. & Vetrano, S., Jul 2012, In : Annals of the New York Academy of Sciences. 1258, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

2011

Colitis-associated cancer: The dark side of inflammatory bowel disease

Danese, S., Malesci, A. & Vetrano, S., Dec 2011, In : Gut. 60, 12, p. 1609-1610 2 p.

Research output: Contribution to journalArticle

Enhanced platelet adhesion induces angiogenesis in intestinal inflammation and inflammatory bowel disease microvasculature

Rutella, S., Vetrano, S., Correale, C., Graziani, C., Sturm, A., Spinelli, A., De Cristofaro, R., Repici, A., Malesci, A. & Danese, S., Mar 2011, In : Journal of Cellular and Molecular Medicine. 15, 3, p. 625-634 10 p.

Research output: Contribution to journalArticle

Infliximab therapy inhibits inflammation-induced angiogenesis in the mucosa of patients with crohn's disease

Rutella, S., Fiorino, G., Vetrano, S., Correale, C., Spinelli, A., Pagano, N., Arena, V., Maggiano, N., Repici, A., Malesci, A. & Danese, S., Apr 2011, In : American Journal of Gastroenterology. 106, 4, p. 762-770 9 p.

Research output: Contribution to journalArticle

Involvement of CD40-CD40 Ligand in uncomplicated and refractory celiac disease

Di Sabatino, A., Rovedatti, L., Vetrano, S., Vidali, F., Biancheri, P., Rescigno, M., Danese, S., MacDonald, T. T. & Corazza, G. R., Mar 2011, In : American Journal of Gastroenterology. 106, 3, p. 519-527 9 p.

Research output: Contribution to journalArticle

Unexpected role of anticoagulant protein C in controlling epithelial barrier integrity and intestinal inflammation

Vetrano, S., Ploplis, V. A., Sala, E., Sandoval-Cooper, M., Donahue, D. L., Correale, C., Arena, V., Spinelli, A., Repici, A., Malesci, A., Castellino, F. J. & Danese, S., Dec 6 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 49, p. 19830-19835 6 p.

Research output: Contribution to journalArticle

2010

Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease

Laverny, G., Penna, G., Vetrano, S., Correale, C., Nebuloni, M., Danese, S. & Adorini, L., Jun 2010, In : Immunology Letters. 131, 1, p. 49-58 10 p.

Research output: Contribution to journalArticle

Narrow-band imaging endoscopy to assess mucosal angiogenesis in inflammatory bowel disease: A pilot study

Danese, S., Fiorino, G., Angelucci, E., Vetrano, S., Pagano, N., Rando, G., Spinelli, A., Malesci, A. & Repici, A., May 21 2010, In : World Journal of Gastroenterology. 16, 19, p. 2396-2400 5 p.

Research output: Contribution to journalArticle

The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6

Vetrano, S., Borroni, E. M., Sarukhan, A., Savino, B., Bonecchi, R., Correale, C., Arena, V., Fantini, M., Roncalli, M., Malesci, A., Mantovani, A., Locati, M. & Danese, S., Feb 2010, In : Gut. 59, 2, p. 197-206 10 p.

Research output: Contribution to journalArticle

The protein C pathway in tissue inflammation and injury: Pathogenic role and therapeutic implications

Danese, S., Vetrano, S., Li, Z., Poplis, V. A. & Castellino, F. J., Feb 11 2010, In : Blood. 115, 6, p. 1121-1131 11 p.

Research output: Contribution to journalArticle

2009

The role of JAM-A in inflammatory bowel disease: Unrevealing the ties that bind

Vetrano, S. & Danese, S., May 2009, Annals of the New York Academy of Sciences. Vol. 1165. p. 308-313 6 p. (Annals of the New York Academy of Sciences; vol. 1165).

Research output: Chapter in Book/Report/Conference proceedingChapter

The role of MAPK in governing lymphocyte adhesion to and migration across the microvasculature in inflammatory bowel disease

Scaldaferri, F., Sans, M., Vetrano, S., Correale, C., Arena, V., Pagano, N., Rando, G., Romeo, F., Potenza, A. E., Repici, A., Malesci, A. & Danese, S., 2009, In : European Journal of Immunology. 39, 1, p. 290-300 11 p.

Research output: Contribution to journalArticle

VEGF-A Links Angiogenesis and Inflammation in Inflammatory Bowel Disease Pathogenesis

Scaldaferri, F., Vetrano, S., Sans, M., Arena, V., Straface, G., Stigliano, E., Repici, A., Sturm, A., Malesci, A., Panes, J., Yla-Herttuala, S., Fiocchi, C. & Danese, S., Feb 2009, In : Gastroenterology. 136, 2

Research output: Contribution to journalArticle

2008

Colifagina, a novel preparation of 8 lysed bacteria ameliorates experimental colitis

Vetrano, S., Correale, C., Borroni, E. M., Pagano, N., Savino, B., Locati, M., Malesci, A., Repici, A. & Danese, S., Apr 2008, In : International Journal of Immunopathology and Pharmacology. 21, 2, p. 401-407 7 p.

Research output: Contribution to journalArticle

Multiple pathogenic roles of microvasculature in inflammatory bowel disease: A jack of all trades

Deban, L., Correale, C., Vetrano, S., Malesci, A. & Danese, S., Jun 2008, In : American Journal of Pathology. 172, 6, p. 1457-1466 10 p.

Research output: Contribution to journalArticle

New insights into inflammatory bowel disease pathophysiology: Paving the way for novel therapeutic targets

Stefanelli, T., Malesci, A., Repici, A., Vetrano, S. & Danese, S., May 2008, In : Current Drug Targets. 9, 5, p. 413-418 6 p.

Research output: Contribution to journalArticle

Unique Role of Junctional Adhesion Molecule-A in Maintaining Mucosal Homeostasis in Inflammatory Bowel Disease

Vetrano, S., Rescigno, M., Rosaria Cera, M., Correale, C., Rumio, C., Doni, A., Fantini, M., Sturm, A., Borroni, E., Repici, A., Locati, M., Malesci, A., Dejana, E. & Danese, S., Jul 2008, In : Gastroenterology. 135, 1, p. 173-184 12 p.

Research output: Contribution to journalArticle

2007

Critical role of the CD40-CD40-ligand pathway in regulating mucosal inflammation-driven angiogenesis in inflammatory bowel disease

Danese, S., Scaldaferri, F., Vetrano, S., Stefanelli, T., Graziani, C., Repici, A., Ricci, R., Straface, G., Sgambato, A., Malesci, A., Fiocchi, C. & Rutella, S., Sep 2007, In : Gut. 56, 9, p. 1248-1256 9 p.

Research output: Contribution to journalArticle