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Research Output 2017 2020

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Article
2020

Drug repurposing for anticancer therapies. A lesson from proton pump inhibitors

Spugnini, E. P. & Fais, S., Jan 2 2020, In : Expert Opinion on Therapeutic Patents. 30, 1, p. 15-25 11 p.

Research output: Contribution to journalArticle

Drug Repositioning
Proton Pump Inhibitors
Medical Economics
Proton-Translocating ATPases
Tumor Microenvironment
2019

Human primary macrophages scavenge AuNPs and eliminate it through exosomes. A natural shuttling for nanomaterials

Logozzi, M., Mizzoni, D., Bocca, B., Di Raimo, R., Petrucci, F., Caimi, S., Alimonti, A., Falchi, M., Cappello, F., Campanella, C., Bavisotto, C. C., David, S., Bucchieri, F., Angelini, D. F., Battistini, L. & Fais, S., Apr 1 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 23-36 14 p.

Research output: Contribution to journalArticle

Exosomes
Nanostructures
Macrophages
Nanoparticles
Endocytosis

Increased plasmatic levels of psa-expressing exosomes distinguish prostate cancer patients from benign prostatic hyperplasia: A prospective study

Logozzi, M., Angelini, D. F., Giuliani, A., Mizzoni, D., Raimo, R. D., Maggi, M., Gentilucci, A., Marzio, V., Salciccia, S., Borsellino, G., Battistini, L., Sciarra, A. & Fais, S., Oct 1 2019, In : Cancers. 11, 10, 1449.

Research output: Contribution to journalArticle

Open Access
Exosomes
Prostatic Hyperplasia
Prostatic Neoplasms
Prospective Studies
Prostate-Specific Antigen

Plasmatic exosomes from prostate cancer patients show increased carbonic anhydrase IX expression and activity and low pH

Logozzi, M., Mizzoni, D., Capasso, C., Del Prete, S., Di Raimo, R., Falchi, M., Angelini, D. F., Sciarra, A., Maggi, M., Supuran, C. T. & Fais, S., Dec 2019, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 35, 1, p. 280-288 9 p.

Research output: Contribution to journalArticle

Open Access
Exosomes
Prostatic Neoplasms
Prostate
Carcinoma
Neoplasms
2018

A role of tumor-released exosomes in paracrine dissemination and metastasis

Spugnini, E. P., Logozzi, M., Di Raimo, R., Mizzoni, D. & Fais, S., 2018, In : International Journal of Molecular Sciences. 19, 12

Research output: Contribution to journalArticle

Exosomes
metastasis
Tumors
tumors
Neoplasm Metastasis

Cell-in-cell phenomena, cannibalism, and autophagy: is there a relationship?

Fais, S. & Overholtzer, M., Jan 24 2018, In : Cell death & disease. 9, 2, p. 95

Research output: Contribution to journalArticle

Microenvironmental pH and exosome levels interplay in human cancer cell lines of different histotypes

Logozzi, M., Mizzoni, D., Angelini, D. F., Di Raimo, R., Falchi, M., Battistini, L. & Fais, S., Oct 5 2018, In : Cancers. 10, 10

Research output: Contribution to journalArticle

Exosomes
Cell Line
Neoplasms
Osteosarcoma
Tumor Cell Line

Microenvironmental pH and Exosome Levels Interplay in Human Cancer Cell Lines of Different Histotypes

Logozzi, M., Mizzoni, D., Angelini, D. F., Di Raimo, R., Falchi, M., Battistini, L. & Fais, S., Oct 5 2018, In : Cancers. 10, 10

Research output: Contribution to journalArticle

Exosomes
Cell Line
Neoplasms
Osteosarcoma
Tumor Cell Line

Moving the systemic evolutionary approach to cancer forward: Therapeutic implications

Mazzocca, A., Ferraro, G., Misciagna, G. & Fais, S., Dec 2018, In : Medical Hypotheses. 121, p. 80-87 8 p.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
Pharmacology
Electromagnetic Fields
Symbiosis
2017

Acridine orange/exosomes increase the delivery and the effectiveness of acridine orange in human melanoma cells: A new prototype for theranostics of tumors

Iessi, E., Logozzi, M., Lugini, L., Azzarito, T., Federici, C., Spugnini, E. P., Mizzoni, D., Di Raimo, R., Angelini, D. F., Battistini, L., Cecchetti, S. & Fais, S., 2017, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 648-657 10 p.

Research output: Contribution to journalArticle

Exosomes
Acridine Orange
Melanoma
Neoplasms
Theranostic Nanomedicine

Antitumor effect of combination of the inhibitors of two new oncotargets: Proton pumps and reverse transcriptase

Lugini, L., Sciamanna, I., Federici, C., Iessi, E., Spugnini, E. P. & Fais, S., Jan 1 2017, In : Oncotarget. 8, 3, p. 4147-4155 9 p.

Research output: Contribution to journalArticle

efavirenz
Lansoprazole
Proton Pumps
RNA-Directed DNA Polymerase
Reverse Transcriptase Inhibitors

European Network on Microvesicles and Exosomes in Health and Disease (ME-HaD)

O'Driscoll, L., Stoorvogel, W., Théry, C., Buzas, E., Nazarenko, I., Siljander, P., Yáñez-Mó, M., Fais, S., Giebel, B. & Yliperttula, M., 2017, In : European Journal of Pharmaceutical Sciences. 98, p. 1-3 3 p.

Research output: Contribution to journalArticle

Exosome levels in human body fluids: A tumor marker by themselves?

Cappello, F., Logozzi, M., Campanella, C., Bavisotto, C. C., Marcilla, A., Properzi, F. & Fais, S., Jan 1 2017, In : European Journal of Pharmaceutical Sciences. 96, p. 93-98 6 p.

Research output: Contribution to journalArticle

Exosomes
Body Fluids
Tumor Biomarkers
Human Body
Neoplasms

Increased PSA expression on prostate cancer exosomes in in vitro condition and in cancer patients

Logozzi, M., Angelini, D. F., Iessi, E., Mizzoni, D., Di Raimo, R., Federici, C., Lugini, L., Borsellino, G., Gentilucci, A., Pierella, F., Marzio, V., Sciarra, A., Battistini, L. & Fais, S., 2017, In : Cancer Letters. 403, p. 318-329 12 p.

Research output: Contribution to journalArticle

Exosomes
Prostate-Specific Antigen
Prostatic Neoplasms
Neoplasms
Prostatic Hyperplasia

Systemic alkalinisation delays prostate cancer cell progression in TRAMP mice

Astigiano, S., Puglisi, A., Mastracci, L., Fais, S. & Barbieri, O., 2017, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 363-368 6 p.

Research output: Contribution to journalArticle

Prostate
Prostatic Neoplasms
Adenocarcinoma
Tumor Microenvironment
Chemoprevention