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2013

Diagnostic and prognostic value of low QRS voltages in cardiac AL amyloidosis

Mussinelli, R., Salinaro, F., Alogna, A., Boldrini, M., Raimondi, A., Musca, F., Palladini, G., Merlini, G. & Perlini, S., May 2013, In : Annals of Noninvasive Electrocardiology. 18, 3, p. 271-280 10 p.

Research output: Contribution to journalArticle

Amyloidosis
Electrocardiography
Sensitivity and Specificity
Survival
Lead

Disease profile and differential diagnosis of hereditary transthyretin-related amyloidosis with exclusively cardiac phenotype: An Italian perspective

Rapezzi, C., Quarta, C. C., Obici, L., Perfetto, F., Longhi, S., Salvi, F., Biagini, E., Lorenzini, M., Grigioni, F., Leone, O., Cappelli, F., Palladini, G., Rimessi, P., Ferlini, A., Arpesella, G., Pinna, A. D., Merlini, G. & Perlini, S., Feb 14 2013, In : European Heart Journal. 34, 7, p. 520-528 9 p.

Research output: Contribution to journalArticle

Differential Diagnosis
Hypertrophic Cardiomyopathy
Amyloidosis
Phenotype
Nervous System

Early development of metabolic syndrome in patients subjected to lung transplantation

Savioli, G., Surbone, S., Giovi, I., Salinaro, F., Preti, P., Meloni, F., Oggionni, T. & Perlini, S., May 2013, In : Clinical Transplantation. 27, 3

Research output: Contribution to journalArticle

Lung Transplantation
Hypertension
Organ Transplantation
Immunosuppressive Agents
Dyslipidemias

Effects of tafamidis on transthyretin stabilization and clinical outcomes in patients with non-Val30Met transthyretin amyloidosis

Merlini, G., Planté-Bordeneuve, V., Judge, D. P., Schmidt, H., Obici, L., Perlini, S., Packman, J., Tripp, T. & Grogan, D. R., Dec 2013, In : Journal of Cardiovascular Translational Research. 6, 6, p. 1011-1020 10 p.

Research output: Contribution to journalArticle

Prealbumin
Brain Natriuretic Peptide
Body Mass Index
Biomarkers
Quality of Life

From hypertension to hypertrophy to heart failure: The role of cardiotrophin-1

Schillaci, G., Pucci, G. & Perlini, S., 2013, In : Journal of Hypertension. 31, 3, p. 474-476 3 p.

Research output: Contribution to journalArticle

High 99mTc-DPD myocardial uptake in a patient with apolipoprotein AI-related amyloidotic cardiomyopathy

Quarta, C. C., Obici, L., Guidalotti, P. L., Pieroni, M., Longhi, S., Perlini, S., Verga, L., Merlini, G. & Rapezzi, C., Mar 2013, In : Amyloid. 20, 1, p. 48-51 4 p.

Research output: Contribution to journalArticle

Apolipoprotein A-I
Cardiomyopathies
Amyloidosis
Biopsy
Prealbumin

Hypertension and stable coronary artery disease: An overview

Pedrinelli, R., Ballo, P., Fiorentini, C., Galderisi, M., Ganau, A., Germanò, G., Innelli, P., Paini, A., Perlini, S., Salvetti, M. & Zacà, V., Aug 2013, In : Journal of Cardiovascular Medicine. 14, 8, p. 545-552 8 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Antihypertensive Agents
Blood Pressure
Hypertension
Amlodipine

Hypertension-related target organ damage: Is it a continuum?

Perlini, S. & Grassi, G., Jun 2013, In : Journal of Hypertension. 31, 6, p. 1083-1085 3 p.

Research output: Contribution to journalArticle

Prevalence and prognostic value of conduction disturbances at the time of diagnosis of cardiac AL amyloidosis

Boldrini, M., Salinaro, F., Mussinelli, R., Raimondi, A., Alogna, A., Musca, F., Palladini, G., Merlini, G. & Perlini, S., Jul 2013, In : Annals of Noninvasive Electrocardiology. 18, 4, p. 327-335 9 p.

Research output: Contribution to journalArticle

Amyloidosis
Electrocardiography
Mortality

Prognostic value of fragmented QRS in cardiac AL amyloidosis

Perlini, S., Salinaro, F., Cappelli, F., Perfetto, F., Bergesio, F., Alogna, A., Mussinelli, R., Boldrini, M., Raimondi, A., Musca, F., Palladini, G. & Merlini, G., Sep 1 2013, In : International Journal of Cardiology. 167, 5, p. 2156-2161 6 p.

Research output: Contribution to journalArticle

Amyloidosis
Amyloid
Kaplan-Meier Estimate
Survival Analysis
Cardiac Myocytes

Pulse pressure and heart rate in patients with metabolic syndrome across Europe: Insights from the GOOD survey

Perlini, S., Naditch-Brule, L., Farsang, C., Zidek, W. & Kjeldsen, S. E., Jul 2013, In : Journal of Human Hypertension. 27, 7, p. 412-416 5 p.

Research output: Contribution to journalArticle

Heart Rate
Blood Pressure
Hypertension
Type 2 Diabetes Mellitus
Surveys and Questionnaires
2012

Best use of cardiac biomarkers in patients with AL amyloidosis and renal failure

Palladini, G., Foli, A., Milani, P., Russo, P., Albertini, R., Lavatelli, F., Obici, L., Perlini, S., Moratti, R. & Merlini, G., May 2012, In : American Journal of Hematology. 87, 5, p. 465-471 7 p.

Research output: Contribution to journalArticle

Amyloidosis
Glomerular Filtration Rate
Natriuretic Peptides
Renal Insufficiency
Biomarkers

Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: A phase II study

Obici, L., Cortese, A., Lozza, A., Lucchetti, J., Gobbi, M., Palladini, G., Perlini, S., Saraiva, M. J. & Merlini, G., Jun 2012, In : Amyloid. 19, SUPPL. 1, p. 34-36 3 p.

Research output: Contribution to journalArticle

Doxycycline
Amyloidosis
Cardiomyopathies
Lower Extremity
Pharmacokinetics

Hypertension and acute myocardial infarction: an overview.

Pedrinelli, R., Ballo, P., Fiorentini, C., Denti, S., Galderisi, M., Ganau, A., Germanò, G., Innelli, P., Paini, A., Perlini, S., Salvetti, M., Zacà, V. & Gruppo di Studio Ipertensione e Cuore, Societa' Italiana di Cardiologia, D. S. I. E. C. S. I. D. C., Mar 2012, In : Journal of Cardiovascular Medicine. 13, 3, p. 194-202 9 p.

Research output: Contribution to journalArticle

Myocardial Infarction
Blood Pressure
Hypertension
Angiotensin Receptors
Mortality

Lobe-specific heterogeneity and matrix metalloproteinase activation after ischemia/reperfusion injury in rat livers

Palladini, G., Ferrigno, A., Rizzo, V., Boncompagni, E., Richelmi, P., Freitas, I., Perlini, S. & Vairetti, M., Jul 2012, In : Toxicologic Pathology. 40, 5, p. 722-730 9 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Matrix Metalloproteinases
Liver
Rats
Chemical activation

Right ventricular function in AL amyloidosis: Characteristics and prognostic implication

Cappelli, F., Porciani, M. C., Bergesio, F., Perlini, S., Attanà, P., Pignone, A. M., Salinaro, F., Musca, F., Padeletti, L. & Perfetto, F., May 2012, In : European Heart Journal Cardiovascular Imaging. 13, 5, p. 416-422 7 p.

Research output: Contribution to journalArticle

Right Ventricular Function
Amyloidosis
Heart Ventricles
Brain Natriuretic Peptide
Amyloid

The repertoire of λ light chains causing predominant amyloid heart involvement and identification of a preferentially involved germline gene, IGLV1-44

Perfetti, V., Palladini, G., Casarini, S., Navazza, V., Rognoni, P., Obici, L., Invernizzi, R., Perlini, S., Klersy, C. & Merlini, G., Jan 5 2012, In : Blood. 119, 1, p. 144-150 7 p.

Research output: Contribution to journalArticle

Amyloid
Genes
Light
Amyloidosis
Logistics
2011

Distinct mechanisms for diastolic dysfunction in diabetes mellitus and chronic pressure-overload

Falcão-Pires, I., Palladini, G., Goņalves, N., Van Der Velden, J., Moreira-Goņalves, D., Miranda-Silva, D., Salinaro, F., Paulus, W. J., Niessen, H. W. M., Perlini, S. & Leite-Moreira, A. F., Sep 2011, In : Basic Research in Cardiology. 106, 5, p. 801-814 14 p.

Research output: Contribution to journalArticle

Diabetes Mellitus
Pressure
Myofibrils
Matrix Metalloproteinases
Tissue Inhibitor of Metalloproteinase-1

Functional correlates of N-terminal natriuretic peptide type B (NT-proBNP) response to therapy in cardiac light chain (AL) amyloidosis

Perlini, S., Musca, F., Salinaro, F., Fracchioni, I., Palladini, G., Obici, L., Albertini, R., Moratti, R., Lavatelli, F., Palladini, G., Rapezzi, C. & Merlini, G., Jun 2011, In : Amyloid. 18, SUPPL. 1, p. 96-97 2 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Amyloidosis
Light
Drug Therapy
Therapeutics

Functional correlates of N-terminal natriuretic peptide type B (NT-proBNP) response to therapy in cardiac light chain (AL) amyloidosis.

Perlini, S., Musca, F., Salinaro, F., Fracchioni, I., Palladini, G., Obici, L., Albertini, R., Moratti, R., Lavatelli, F., Palladini, G., Rapezzi, C. & Merlini, G., Jun 2011, In : Amyloid. 18 Suppl 1, p. 91-92 2 p.

Research output: Contribution to journalArticle

Midregional proadrenomedullin (MR-proADM) is a powerful predictor of early death in AL amyloidosis

Palladini, G., Barassi, A., Perlini, S., Milani, P., Foli, A., Russo, P., Albertini, R., Obici, L., Lavatelli, F., Sarais, G., Casarini, S., Moratti, R., Melzi D'Eril, G. V. & Merlini, G., Dec 2011, In : Amyloid. 18, 4, p. 216-221 6 p.

Research output: Contribution to journalArticle

Amyloidosis
Adrenomedullin
Troponin
Survival
Brain Natriuretic Peptide

Proteomic characterization of amyloid deposits in transthyretin amyloidosis associated with various mutations

Valentini, V., Lavatelli, F., Obici, L., Donadei, S., Perlini, S., Palladini, G. & Merlini, G., Jun 2011, In : Amyloid. 18, SUPPL. 1, p. 61-63 3 p.

Research output: Contribution to journalArticle

Prealbumin
Amyloid Plaques
Electrophoresis, Gel, Two-Dimensional
Proteomics
Mass Spectrometry

Proteomic characterization of amyloid deposits in transthyretin amyloidosis associated with various mutations.

Valentini, V., Lavatelli, F., Obici, L., Donadei, S., Perlini, S., Palladini, G. & Merlini, G., Jun 2011, In : Amyloid. 18 Suppl 1, p. 56-58 3 p.

Research output: Contribution to journalArticle

2010

Prevention of myocardial fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in diabetic rats

Castoldi, G., di Gioia, C. R. T., Bombardi, C., Perego, C., Perego, L., Mancini, M., Leopizzi, M., Gorradi, B., Perlini, S., Zerbini, G. & Stella, A., 2010, In : Clinical Science. 118, 3, p. 211-220 10 p.

Research output: Contribution to journalArticle

Fibrosis
Ramipril
Transforming Growth Factors
Diabetic Cardiomyopathies
Insulin

The combination of high-sensitivity cardiac troponin T (hs-cTnT) at presentation and changes in N-terminal natriuretic peptide type B (NT-proBNP) after chemotherapy best predicts survival in AL amyloidosis

Palladini, G., Barassi, A., Klersy, C., Pacciolla, R., Milani, P., Sarais, G., Perlini, S., Albertini, R., Russo, P., Foli, A., Bragotti, L. Z., Obici, L., Moratti, R., D'Eril, G. V. M. & Merlini, G., Nov 4 2010, In : Blood. 116, 18, p. 3426-3430 5 p.

Research output: Contribution to journalArticle

Troponin T
Chemotherapy
Brain Natriuretic Peptide
Amyloidosis
Drug Therapy
2009

Blood pressure control and components of the metabolic syndrome: The GOOD survey

Zidek, W., Naditch-Brûlé, L., Perlini, S., Farsang, C. & Kjeldsen, S. E., Sep 15 2009, In : Cardiovascular Diabetology. 8, p. 51 1 p., 1475.

Research output: Contribution to journalArticle

Blood Pressure
Diabetes Mellitus
Hypertension
HDL Cholesterol
Antihypertensive Agents

Il ruolo degli ACE-inibitori nella prevenzione delle recidive di fibrillazione atriale isolata in pazienti normotesi

Translated title of the contribution: Role of ACE-inhibitors in preventing atrial fibrillation relapses in normotensive patientsBelluzzi, F., Sernesi, L., Centola, M. & Perlini, S., 2009, In : Recenti Progressi in Medicina. 100, 11, p. 508-511 4 p.

Research output: Contribution to journalArticle

Angiotensin-Converting Enzyme Inhibitors
Angiotensin II
Atrial Fibrillation
Recurrence
Ramipril

Inter-regional comparisons of the prevalence of cardiometabolic risk factors in patients with hypertension in Europe: The GOOD survey

Farsang, C., Naditch-Brule, L., Perlini, S., Zidek, W. & Kjeldsen, S. E., 2009, In : Journal of Human Hypertension. 23, 5, p. 316-324 9 p.

Research output: Contribution to journalArticle

Mediterranean Region
Hypertension
Hungary
Ambulatory Care
Type 2 Diabetes Mellitus

Prevention of Recurrent Lone Atrial Fibrillation by the Angiotensin-II Converting Enzyme Inhibitor Ramipril in Normotensive Patients

Belluzzi, F., Sernesi, L., Preti, P., Salinaro, F., Fonte, M. L. & Perlini, S., Jan 6 2009, In : Journal of the American College of Cardiology. 53, 1, p. 24-29 6 p.

Research output: Contribution to journalArticle

Ramipril
Angiotensin-Converting Enzyme Inhibitors
Angiotensin II
Atrial Fibrillation
Recurrence

Systemic cardiac amyloidoses: Disease profiles and clinical courses of the 3 main types

Rapezzi, C., Merlini, G., Quarta, C. C., Riva, L., Longhi, S., Leone, O., Salvi, F., Ciliberti, P., Pastorelli, F., Biagini, E., Coccolo, F., Cooke, R. M. T., Bacchi-Reggiani, L., Sangiorgi, D., Ferlini, A., Cavo, M., Zamagni, E., Fonte, M. L., Palladini, G., Salinaro, F. & 4 others, Musca, F., Obici, L., Branzi, A. & Perlini, S., Sep 2009, In : Circulation. 120, 13, p. 1203-1212 10 p.

Research output: Contribution to journalArticle

Amyloidosis
Heart Diseases
Prealbumin
Immunoglobulin Light Chains
Cardiomyopathies

Treatment of patients with advanced cardiac AL amyloidosis with oral melphalan, dexamethasone, and thalidomide

Palladini, G., Russo, P., Lavatelli, F., Nuvolone, M., Albertini, R., Bosoni, T., Perfetti, V., Obici, L., Perlini, S., Moratti, R. & Merlini, G., 2009, In : Annals of Hematology. 88, 4, p. 347-350 4 p.

Research output: Contribution to journalArticle

Melphalan
Thalidomide
Amyloidosis
Dexamethasone
Therapeutics
2008

Arterial hypertension and cardiac damage: Diagnostic and therapeutic guidelines

Agabiti Rosei, E., De Simone, G., Mureddu, G., Trimarco, B., Verdecchia, P., Volpe, M., Muiesan, M. L., Ambrosioni, E., Bernini, G., Cerasola, G., De Divitiis, O., Di Somma, S., Degli Esposti, E., Fiorentini, C., Ganau, A., Grandi, A. M., Grassi, G., Leonetti, G., Mancia, G., Manfellotto, D. & 8 others, Mezzetti, A., Palombo, C., Perlini, S., Pessina, A., Rappelli, A., Rossi, G., Salvetti, A. & Veglio, F., 2008, In : High Blood Pressure and Cardiovascular Prevention. 15, 3, p. 141-170 30 p.

Research output: Contribution to journalArticle

Guidelines
Hypertension
Therapeutics
Familial Mediterranean Fever
Cardiology

Direct renin inhibition: Another weapon to modulate the renin-angiotensin system in postinfarction remodeling?

Perlini, S., Salinaro, F. & Fonte, M. L., Dec 2008, In : Hypertension. 52, 6, p. 1019-1021 3 p.

Research output: Contribution to journalArticle

Gender-related risk of myocardial involvement in systemic amyloidosis

Rapezzi, C., Riva, L., Quarta, C. C., Perugini, E., Salvi, F., Longhi, S., Ciliberti, P., Pastorelli, F., Biagini, E., Leone, O., Cooke, R. M. T., Bacchi-Reggiani, L., Ferlini, A., Cavo, M., Merlini, G., Perlini, S., Pasquali, S. & Branzi, A., 2008, In : Amyloid. 15, 1, p. 40-48 9 p.

Research output: Contribution to journalArticle

Amyloidosis
Women's Rights
Gonadal Steroid Hormones
Cardiomyopathies
Left Ventricular Function

Increased prevalence of metabolic syndrome in uncontrolled hypertension across Europe: The Global Cardiometabolic Risk Profile in Patients with hypertension disease survey

Kjeldsen, S. E., Naditch-Brule, L., Perlini, S., Zidek, W. & Farsang, C., Oct 2008, In : Journal of Hypertension. 26, 10, p. 2064-2070 7 p.

Research output: Contribution to journalArticle

Blood Pressure
Hypertension
Surveys and Questionnaires
Type 2 Diabetes Mellitus
Waist Circumference

Ipertensione arteriosa e patologia cardiaca: Linee guida diagnostico-terapeutiche

Translated title of the contribution: Hypertensive heart disease: Diagnostic and therapeutic guidelinesRosei, E. A., de Simone, G., Mureddu, G. F., Trimarco, B., Verdecchia, P., Volpe, M., Muiesan, M. L., Ambrosioni, E., Bernini, G., Cerasola, G., de Divitiis, O., Di Somma, S., Esposti, E. D., Fiorentini, C., Ganau, A., Grandi, A. M., Grassi, G., Leonetti, G., Mancia, G., Manfellotto, D. & 8 others, Mezzetti, A., Palombo, C., Perlini, S., Pessina, A., Rappelli, A., Rossi, G., Salvetti, A. & Veglio, F., Jun 2008, In : Giornale Italiano di Cardiologia. 9, 6, p. 427-454 28 p.

Research output: Contribution to journalArticle

Sistema renina angiotensina e fibrillazione atriale

Translated title of the contribution: Renin-angiotensin system and atrial fibrillationResasco, T., Fonte, M. L., Salinaro, F., Preti, P. & Perlini, S., 2008, In : Rivista Italiana di Neurobiologia. 5, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

2007

Adenosine A1 receptor expression during the transition from compensated pressure overload hypertrophy to heart failure

Perlini, S., Arosio, B., Parmeggiani, L., Santambrogio, D., Palladini, G., Tozzi, R., Gatti, C., Annoni, G., Meyer, T. E. & Ferrari, A. U., Feb 2007, In : Journal of Hypertension. 25, 2, p. 449-454 6 p.

Research output: Contribution to journalArticle

Adenosine A1 Receptors
Hypertrophy
Heart Failure
Pressure
Adenosine

Importance of the echocardiographic evaluation of right ventricular function in patients with AL amyloidosis

Ghio, S., Perlini, S., Palladini, G., Marsan, N. A., Faggiano, G., Vezzoli, M., Klersy, C., Campana, C., Merlini, G. & Tavazzi, L., Aug 2007, In : European Journal of Heart Failure. 9, 8, p. 808-813 6 p.

Research output: Contribution to journalArticle

Right Ventricular Function
Amyloidosis
Stroke Volume
Heart Ventricles
Heart Failure

Matrix Metalloprotease Activity Is Enhanced in the Compensated but Not in the Decompensated Phase of Pressure Overload Hypertrophy

Tozzi, R., Palladini, G., Fallarini, S., Nano, R., Gatti, C., Presotto, C., Schiavone, A., Micheletti, R., Ferrari, P., Fogari, R. & Perlini, S., Jun 2007, In : American Journal of Hypertension. 20, 6, p. 663-669 7 p.

Research output: Contribution to journalArticle

Metalloproteases
Hypertrophy
Heart Failure
Pressure
Collagen
2006

Circulating amyloidogenic free light chains and serum N-terminal natriuretic peptide type B decrease simultaneously in association with improvement of survival in AL

Palladini, G., Lavatelli, F., Russo, P., Perlini, S., Perfetti, V., Bosoni, T., Obici, L., Bradwell, A. R., D'Eril, G. M., Fogari, R., Moratti, R. & Merlini, G., May 15 2006, In : Blood. 107, 10, p. 3854-3858 5 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Amyloidosis
Association reactions
Light
Survival

Histochemical study of cardiac mast cells degranulation and collagen deposition: Interaction with the cathecolaminergic system in the rat

Facoetti, A., Fallarini, S., Miserere, S., Bertolotti, A., Ferrero, I., Tozzi, R., Gatti, C., Palladini, G., Perlini, S. & Nano, R., Apr 2006, In : European journal of histochemistry : EJH. 50, 2, p. 133-140 8 p.

Research output: Contribution to journalArticle

Cell Degranulation
mast cells
Mast Cells
collagen
Collagen

Survival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure

Perlini, S., Ferrero, I., Palladini, G., Tozzi, R., Gatti, C., Vezzoli, M., Cesana, F., Janetti, M. B., Clari, F., Busca, G., Mancia, G. & Ferrari, A. U., Jul 2006, In : Hypertension. 48, 1, p. 93-97 5 p.

Research output: Contribution to journalArticle

Adrenergic Antagonists
Left Ventricular Hypertrophy
Doxazosin
Pressure
Survival

Time course of matrix metalloproteases and tissue inhibitors in bleomycin-induced pulmonary fibrosis

Oggionni, T., Morbini, P., Inghilleri, S., Palladini, G., Tozzi, R., Vitulo, P., Fenoglio, C., Perlini, S. & Pozzi, E., Oct 2006, In : European journal of histochemistry : EJH. 50, 4, p. 317-325 9 p.

Research output: Contribution to journalArticle

Pulmonary Fibrosis
Metalloproteases
metalloproteinases
Matrix Metalloproteinases
fibrosis
Idiopathic Thrombocytopenic Purpura
Rhabdomyosarcoma
Heart Failure
Neoplasm Metastasis
Sarcoma
2005
Ramipril
Italy
Cost-Benefit Analysis
Costs and Cost Analysis
Therapeutics

Peripheral blood progenitor cell mobilization and collection in 42 patients with primary systemic amyloidosis

Perotti, C., Del Fante, C., Viarengo, G., Perlini, S., Vezzoli, M., Rodi, G., Palo, A., Bergamaschi, P. & Salvaneschi, L., Nov 2005, In : Transfusion. 45, 11, p. 1729-1734 6 p.

Research output: Contribution to journalArticle

Blood Cells
Stem Cells
Granulocyte Colony-Stimulating Factor
Amyloidosis
Primary amyloidosis

Sympathectomy or doxazosin, but not propranolol, blunt myocardial interstitial fibrosis in pressure-overload hypertrophy

Perlini, S., Palladini, G., Ferrero, I., Tozzi, R., Fallarini, S., Facoetti, A., Nano, R., Clari, F., Busca, G., Fogari, R. & Ferrari, A. U., Nov 2005, In : Hypertension. 46, 5, p. 1213-1218 6 p.

Research output: Contribution to journalArticle

Doxazosin
Sympathectomy
Propranolol
Hypertrophy
Fibrosis