Tamara Patrizia Canu &ndash; Research Output

2019

The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli

Pedrotti, S., Caccia, R., Neguembor, M. V., Garcia-Manteiga, J. M., Ferri, G., De Palma, C., Canu, T., Giovarelli, M., Marra, P., Fiocchi, A., Molineris, I., Raso, M., Sanvito, F., Doglioni, C., Esposito, A., Clementi, E. & Gabellini, D., Jan 1 2019, In : Science Advances. 5, 4, eaav1472.

Research output: Contribution to journal › Article

Open Access

obesity

stimuli

metabolism

adipose tissues

regulators

2018

Four-class tumor staging for early diagnosis and monitoring of murine pancreatic cancer using magnetic resonance and ultrasound

Dugnani, E., Pasquale, V., Marra, P., Liberati, D., Canu, T., Perani, L., De Sanctis, F., Ugel, S., Invernizzi, F., Citro, A., Venturini, M., Doglioni, C., Esposito, A. & Piemonti, L., 2018, In : Carcinogenesis. 39, 9, p. 1197-1206 10 p.

Research output: Contribution to journal › Article

Neoplasm Staging

Pancreatic Neoplasms

Early Diagnosis

Magnetic Resonance Spectroscopy

Carcinogenesis

On the use of superparamagnetic hydroxyapatite nanoparticles as an agent for magnetic and nuclear in vivo imaging

Adamiano, A., Iafisco, M., Sandri, M., Basini, M., Arosio, P., Canu, T., Sitia, G., Esposito, A., Iannotti, V., Ausanio, G., Fragogeorgi, E., Rouchota, M., Loudos, G., Lascialfari, A. & Tampieri, A., 2018, In : Acta Biomaterialia. 73, 3, p. 458-469 12 p.

Research output: Contribution to journal › Article

Durapatite

Hydroxyapatite

Nanoparticles

Iron

Magnetic Resonance Imaging

4 Citations (Scopus)

Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice

Pisani, C., Strimpakos, G., Gabanella, F., Di Certo, M. G., Onori, A., Severini, C., Luvisetto, S., Farioli-Vecchioli, S., Carrozzo, I., Esposito, A., Canu, T., Mattei, E., Corbi, N. & Passananti, C., Apr 1 2018, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 4, p. 1172-1182 11 p.

Research output: Contribution to journal › Article

Utrophin

Inbred mdx Mouse

Neuromuscular Junction

Zinc Fingers

Transcription Factors

Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice

Pisani, C., Strimpakos, G., Gabanella, F., Di Certo, MG., Onori, A., Severini, C., Luvisetto, S., Farioli-Vecchioli, S., Carrozzo, I., Esposito, A., Canu, T., Mattei, E., Corbi, N. & Passananti, C., 2018, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 4, p. 1172-1182 11 p.

Research output: Contribution to journal › Article

Utrophin

Inbred mdx Mouse

Neuromuscular Junction

Zinc Fingers

Transcription Factors

2017

2 Citations (Scopus)

Modeling the Iatrogenic Pancreatic Cancer Risk After Islet Autotransplantation in Mouse

Dugnani, E., Pasquale, V., Liberati, D., Citro, A., Cantarelli, E., Pellegrini, S., Marra, P., Canu, T., Balzano, G., Scavini, M., Esposito, A., Doglioni, C. & Piemonti, L., 2017, In : American Journal of Transplantation. 17, 10, p. 2720-2727 8 p.

Research output: Contribution to journal › Article

Autologous Transplantation

Pancreatic Neoplasms

Neoplasm Metastasis

Portal Vein

Liver

2016

Leukocytes recruited by tumor-derived HMGB1 sustain peritoneal carcinomatosis

Cottone, L., Capobianco, A., Gualteroni, C., Monno, A., Raccagni, I., Valtorta, S., Canu, T., Di Tomaso, T., Lombardo, A. L., Esposito, A., Moresco, R. M., Del Maschio, A., Naldini, L., Rovere-Querini, P., Bianchi, M. E. & Manfredi, A. A., May 3 2016, In : OncoImmunology. 5, 5, p. - e1122860.

Research output: Contribution to journal › Article

Leukocytes

Carcinoma

Macrophages

Neoplasms

Colon

2015

9 Citations (Scopus)

Effects of short-term manipulation of serum FFA concentrations on left ventricular energy metabolism and function in patients with heart failure: no association with circulating bio-markers of inflammation

Salerno, A., Fragasso, G., Esposito, A., Canu, T., Lattuada, G., Manzoni, G., Del Maschio, A., Margonato, A., De Cobelli, F. & Perseghin, G., Aug 25 2015, In : Acta Diabetologica. 52, 4, p. 753-761 9 p.

Research output: Contribution to journal › Article

Nonesterified Fatty Acids

Energy Metabolism

Heart Failure

Inflammation

Serum

14 Citations (Scopus)

Magnetic resonance imaging allows the evaluation of tissue damage and regeneration in a mouse model of critical limb ischemia

Zaccagnini, G., Palmisano, A., Canu, T., Maimone, B., Russo, F. M. L., Ambrogi, F., Gaetano, C., De Cobelli, F., Del Maschio, A., Esposito, A. & Martelli, F., Nov 10 2015, In : PLoS One. 10, 11, e0142111.

Research output: Contribution to journal › Article

ischemia

limbs (animal)

magnetic resonance imaging

Magnetic resonance imaging

Muscle

2014

9 Citations (Scopus)

7-tesla magnetic resonance imaging precisely and noninvasively reflects inflammation and remodeling of the skeletal muscle in a mouse model of antisynthetase syndrome

Sciorati, C., Esposito, A., Campana, L., Canu, T., Monno, A., Palmisano, A., De Cobelli, F., Del Maschio, A., Ascheman, D. P., Manfredi, A. A. & Rovere-Querini, P., 2014, In : BioMed Research International. 2014, 879703.

Research output: Contribution to journal › Article

Magnetic resonance

Myositis

Muscle

Skeletal Muscle

Magnetic Resonance Imaging

5 Citations (Scopus)

CMR in assessment of cardiac masses: Primary benign tumors

Esposito, A., De Cobelli, F., Ironi, G., Marra, P., Canu, T., Mellone, R. & Del Maschio, A., 2014, In : JACC: Cardiovascular Imaging. 7, 7, p. 733-736 4 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

CMR in the Assessment of Cardiac Masses: Primary Malignant Tumors

Esposito, A., De Cobelli, F., Ironi, G., Marra, P., Canu, T., Mellone, R. & Del Maschio, A., Oct 1 2014, In : JACC: Cardiovascular Imaging. 7, 10, p. 1057-1061 5 p.

Research output: Contribution to journal › Article

28 Citations (Scopus)

Leukocyte HMGB1 is required for vessel remodeling in regenerating muscles

Campana, L., Santarella, F., Esposito, A., Maugeri, N., Rigamonti, E., Monno, A., Canu, T., Del Maschio, A., Bianchi, M. E., Manfredi, A. A. & Rovere-Querini, P., Jun 1 2014, In : Journal of Immunology. 192, 11, p. 5257-5264 8 p.

Research output: Contribution to journal › Article

HMGB1 Protein

Leukocytes

Muscles

Skeletal Muscle

Necrosis

7 Citations (Scopus)

Liver perfusion changes occurring during pancreatic islet engraftment: A dynamic contrast-enhanced magnetic resonance study

Esposito, A., Palmisano, A., Maffi, P., Malosio, M. L., Nano, R., Canu, T., De Cobelli, F., Piemonti, L., Ironi, G., Secchi, A. & Del Maschio, A., Jan 2014, In : American Journal of Transplantation. 14, 1, p. 202-209 8 p.

Research output: Contribution to journal › Article

Islets of Langerhans

Magnetic Resonance Spectroscopy

Perfusion

Liver

Magnetic Resonance Imaging

Mesenchymal stem cells expressing therapeutic genes induce autochthonous prostate tumour regression

Abrate, A., Buono, R., Canu, T., Esposito, A., Del Maschio, A., Lucianò, R., Bettiga, A., Colciago, G., Guazzoni, G., Benigni, F., Hedlund, P., Altaner, C., Montorsi, F. & Cavarretta, I. T. R., 2014, (Accepted/In press) In : European Journal of Cancer.

Research output: Contribution to journal › Article

Mesenchymal Stromal Cells

Prostate

Prostatic Neoplasms

Genes

Neoplasms

2013

25 Citations (Scopus)

Magnetic Resonance Imaging at 7T Reveals Common Events in Age-Related Sarcopenia and in the Homeostatic Response to Muscle Sterile Injury

Esposito, A., Campana, L., Palmisano, A., De Cobelli, F., Canu, T., Santarella, F., Colantoni, C., Monno, A., Vezzoli, M., Pezzetti, G., Manfredi, A. A., Rovere-Querini, P. & De Maschio, A., Mar 12 2013, In : PLoS One. 8, 3, e59308.

Research output: Contribution to journal › Article

sarcopenia

Sarcopenia

magnetic resonance imaging

Muscle

Magnetic Resonance Imaging

2012

7 Citations (Scopus)

Gender influence on dose saving allowed by prospective-triggered 64-slice multidetector computed tomography coronary angiography as compared with retrospective-gated mode

Esposito, A., De Cobelli, F., Colantoni, C., Perseghin, G., Del Vecchio, A., Canu, T., Calandrino, R. & Del Maschio, A., Jul 12 2012, In : International Journal of Cardiology. 158, 2, p. 253-259 7 p.

Research output: Contribution to journal › Article

Multidetector Computed Tomography

Coronary Angiography

Electrocardiography

Computed Tomography Angiography

Radiation

3 Citations (Scopus)

Left ventricular function and energy homeostasis in patients with type 1 diabetes with and without microvascular complications

Perseghin, G., Lattuada, G., De Cobelli, F., Esposito, A., Canu, T., Ragogna, F., Maffi, P., Scifo, P., Secchi, A., Del Maschio, A. & Luzi, L., Jan 26 2012, In : International Journal of Cardiology. 154, 2, p. 111-115 5 p.

Research output: Contribution to journal › Article

Type 1 Diabetes Mellitus

Left Ventricular Function

Homeostasis

Energy Metabolism

Hyperglycemia

2009

4 Citations (Scopus)

Elevated fasting plasma C-peptide occurs in non-diabetic individuals with fatty liver, irrespective of insulin resistance

Perseghin, G., Caumo, A., Lattuada, G., De Cobelli, F., Ntali, G., Esposito, A., Belloni, E., Canu, T., Ragogna, F., Scifo, P., Del Maschio, A. & Luzi, L., Sep 2009, In : Diabetic Medicine. 26, 9, p. 847-854 8 p.

Research output: Contribution to journal › Article

C-Peptide

Fatty Liver

Insulin Resistance

Fasting

Insulin

23 Citations (Scopus)

Impaired left ventricular energy metabolism in patients with hypertrophic cardiomyopathy is related to the extension of fibrosis at delayed gadolinium-enhanced magnetic resonance imaging

Esposito, A., De Cobelli, F., Perseghin, G., Pieroni, M., Belloni, E., Mellone, R., Canu, T., Gentinetta, F., Scifo, P., Chimenti, C., Frustaci, A., Luzi, L., Maseri, A. & Del Maschio, A., Feb 2009, In : Heart. 95, 3, p. 228-233 6 p.

Research output: Contribution to journal › Article

Hypertrophic Cardiomyopathy

Gadolinium

Energy Metabolism

Phosphocreatine

Fibrosis

21 Citations (Scopus)

Improving the procedure for detection of intrahepatic transplanted islets by magnetic resonance imaging

Malosio, M. L., Esposito, A., Poletti, A., Chiaretti, S., Piemonti, L., Melzi, R., Nano, R., Tedoldi, F., Canu, T., Santambrogio, P., Brigatti, C., De Cobelli, F., Maffi, P., Secchi, A. & Del Maschio, A., Oct 2009, In : American Journal of Transplantation. 9, 10, p. 2372-2382 11 p.

Research output: Contribution to journal › Article

Magnets

Magnetic Resonance Imaging

Transplants

Islets of Langerhans Transplantation

Feasibility Studies

19 Citations (Scopus)

Left ventricular function and energy metabolism in middle-aged men undergoing long-lasting sustained aerobic oxidative training

Perseghin, G., Cobelli, F. D., Esposito, A., Belloni, E., Lattuada, G., Canu, T., Invernizzi, P. L., Ragogna, F., Torre, A. L., Scifo, P., Alberti, G., Maschio, A. D. & Luzi, L., Apr 2009, In : Heart. 95, 8, p. 630-635 6 p.

Research output: Contribution to journal › Article

Left Ventricular Function

Energy Metabolism

Phosphocreatine

Exercise

Adenosine Triphosphate

2008

141 Citations (Scopus)

Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver

Perseghin, G., Lattuada, G., De Cobelli, F., Esposito, A., Belloni, E., Ntali, G., Ragogna, F., Canu, T., Scifo, P., Del Maschio, A. & Luzi, L., Jan 2008, In : Hepatology. 47, 1, p. 51-58 8 p.

Research output: Contribution to journal › Article

Fatty Liver

Energy Metabolism

Fats

Insulin Resistance

Magnetic Resonance Spectroscopy

80 Citations (Scopus)

Maturing dendritic cells depend on RAGE for in vivo homing to lymph nodes

Manfredi, A. A., Capobianco, A., Esposito, A., De Cobelli, F., Canu, T., Monno, A., Raucci, A., Sanvito, F., Doglioni, C., Nawroth, P. P., Bierhaus, A., Bianchi, M. E., Rovere-Querini, P. & Del Maschio, A., Feb 15 2008, In : Journal of Immunology. 180, 4, p. 2270-2275 6 p.

Research output: Contribution to journal › Article

Dendritic Cells

Lymph Nodes

T-Lymphocytes

Advanced Glycosylation End Product-Specific Receptor

Nuclear Proteins

16 Citations (Scopus)

MRI of cardiomyopathy

Belloni, E., De Cobelli, F., Esposito, A., Mellone, R., Perseghin, G., Canu, T. & Del Maschio, A., Dec 2008, In : American Journal of Roentgenology. 191, 6, p. 1702-1710 9 p.

Research output: Contribution to journal › Article

Cardiomyopathies

2007

50 Citations (Scopus)

Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance

Perseghin, G., Ntali, G., De Cobelli, F., Lattuada, G., Esposito, A., Belloni, E., Canu, T., Costantino, F., Ragogna, F., Scifo, P., Del Maschio, A. & Luzi, L., May 2007, In : Diabetes Care. 30, 6, p. 1520-1526 7 p.

Research output: Contribution to journal › Article

Energy Metabolism

Insulin Resistance

Magnetic Resonance Spectroscopy

Phosphocreatine

Hyperglycemia

41 Citations (Scopus)

Brief report: Serum retinol-binding protein-4, leptin, and adiponectin concentrations are related to ectopic fat accumulation

Perseghin, G., Lattuada, G., De Cobelli, F., Esposito, A., Belloni, E., Canu, T., Ragogna, F., Scifo, P., Del Maschio, A. & Luzi, L., Dec 2007, In : Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4883-4888 6 p.

Research output: Contribution to journal › Article

Retinol-Binding Proteins

Adiponectin

Leptin

Insulin Resistance

Fats

48 Citations (Scopus)

Effect of the sporting discipline on the right and left ventricular morphology and function of elite male track runners: A magnetic resonance imaging and phosphorus 31 spectroscopy study

Perseghin, G., De Cobelli, F., Esposito, A., Lattuada, G., Terruzzi, I., La Torre, A., Belloni, E., Canu, T., Scifo, P., Del Maschio, A., Luzi, L. & Alberti, G., Nov 2007, In : American Heart Journal. 154, 5, p. 937-942 6 p.

Research output: Contribution to journal › Article

Left Ventricular Function

Athletes

Phosphorus

Spectrum Analysis

Magnetic Resonance Imaging

163 Citations (Scopus)

Habitual physical activity is associated with intrahepatic fat content in humans

Perseghin, G., Lattuada, G., De Cobelli, F., Ragogna, F., Ntali, G., Esposito, A., Belloni, E., Canu, T., Terruzzi, I., Scifo, P., Del Maschio, A. & Luzi, L., Mar 2007, In : Diabetes Care. 30, 3, p. 683-688 6 p.

Research output: Contribution to journal › Article

Fats

Fatty Liver

Insulin Resistance

Adiponectin

Homeostasis

2006

189 Citations (Scopus)

Delayed Gadolinium-Enhanced Cardiac Magnetic Resonance in Patients With Chronic Myocarditis Presenting With Heart Failure or Recurrent Arrhythmias

De Cobelli, F., Pieroni, M., Esposito, A., Chimenti, C., Belloni, E., Mellone, R., Canu, T., Perseghin, G., Gaudio, C., Maseri, A., Frustaci, A. & Del Maschio, A., Apr 18 2006, In : Journal of the American College of Cardiology. 47, 8, p. 1649-1654 6 p.

Research output: Contribution to journal › Article

Myocarditis

Gadolinium

Cardiac Arrhythmias

Magnetic Resonance Spectroscopy

Heart Failure

79 Citations (Scopus)

Insulin resistance and whole body energy homeostasis in obese adolescents with fatty liver disease

Perseghin, G., Bonfanti, R., Magni, S., Lattuada, G., De Cobelli, F., Canu, T., Esposito, A., Scifo, P., Ntali, G., Costantino, F., Bosio, L., Ragogna, F., Del Maschio, A., Chiumello, G. & Luzi, L., 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 291, 4

Research output: Contribution to journal › Article

Fatty Liver

Liver

Insulin Resistance

Liver Diseases

Homeostasis

40 Citations (Scopus)

Serum resistin and hepatic fat content in nondiabetic individuals

Perseghin, G., Lattuada, G., De Cobelli, F., Ntali, G., Esposito, A., Burska, A., Belloni, E., Canu, T., Ragogna, F., Scifo, P., Del Maschio, A. & Luzi, L., Dec 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 5122-5125 4 p.

Research output: Contribution to journal › Article

Resistin

Liver

Fats

Insulin Resistance

Fatty Liver

2005

42 Citations (Scopus)

Cross-sectional assessment of the effect of kidney and kidney-pancreas transplantation on resting left ventricular energy metabolism in type 1 diabetic-uremic patients: A phosphorous-31 magnetic resonance spectroscopy study

Perseghin, G., Fiorina, P., De Cobelli, F., Scifo, P., Esposito, A., Canu, T., Danna, M., Gremizzi, C., Secchi, A., Luzi, L. & Del Maschio, A., Sep 20 2005, In : Journal of the American College of Cardiology. 46, 6, p. 1085-1092 8 p.

Research output: Contribution to journal › Article

Pancreas Transplantation

Kidney Transplantation

Energy Metabolism

Magnetic Resonance Spectroscopy

Kidney

46 Citations (Scopus)

Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes

Perseghin, G., Lattuada, G., De Cobelli, F., Esposito, A., Costantino, F., Canu, T., Scifo, P., De Taddeo, F., Maffi, P., Secchi, A., Del Maschio, A. & Luzi, L., Dec 2005, In : Diabetologia. 48, 12, p. 2615-2621 7 p.

Research output: Contribution to journal › Article

Type 1 Diabetes Mellitus

Fats

Lipids

Glucose

Insulin Resistance