1989 …2019

Research output per year

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Research Output

Open Access

Diagnostic performance of new and classic CSF biomarkers in age-related dementias

Marchegiani, F., Matacchione, G., Ramini, D., Marcheselli, F., Recchioni, R., Casoli, T., Mercuri, E., Lazzarini, M., Giorgetti, B., Cameriere, V., Paolini, S., Paciaroni, L., Rossi, T., Galeazzi, R., Lisa, R., Bonfigli, A. R., Procopio, A. D., De Luca, M., Pelliccioni, G. & Olivieri, F., Apr 30 2019, In : Aging. 11, 8, p. 2420-2429 10 p.

Research output: Contribution to journalArticle

2017
2016

The effect of astaxanthin on the aging rat brain: Gender-related differences in modulating inflammation

Balietti, M., Giannubilo, S. R., Giorgetti, B., Solazzi, M., Turi, A., Casoli, T., Ciavattini, A. & Fattoretti, P., Jan 30 2016, In : Journal of the Science of Food and Agriculture. 96, 2, p. 615-618 4 p.

Research output: Contribution to journalArticle

2015
2014

One-month strawberry-rich anthocyanin supplementation ameliorates cardiovascular risk, oxidative stress markers and platelet activation in humans

Alvarez-Suarez, J. M., Giampieri, F., Tulipani, S., Casoli, T., Di Stefano, G., González-Paramás, A. M., Santos-Buelga, C., Busco, F., Quiles, J. L., Cordero, M. D., Bompadre, S., Mezzetti, B. & Battino, M., Mar 2014, In : Journal of Nutritional Biochemistry. 25, 3, p. 289-294 6 p.

Research output: Contribution to journalArticle

2013

Early selective vulnerability of synapses and synaptic mitochondria in the hippocampal CA1 region of the Tg2576 mouse model of Alzheimer's disease

Balietti, M., Giorgetti, B., Casoli, T., Solazzi, M., Tamagnini, F., Burattini, C., Aicardi, G. & Fattoretti, P., 2013, In : Journal of Alzheimer's Disease. 34, 4, p. 887-896 10 p.

Research output: Contribution to journalArticle

Platelets in Alzheimer's disease-associated cellular senescence and inflammation

Casoli, T., Balietti, M., Giorgetti, B., Solazzi, M., Scarpino, O. & Fattoretti, P., 2013, In : Current Pharmaceutical Design. 19, 9, p. 1727-1738 12 p.

Research output: Contribution to journalArticle

2012

Dynamin binding protein gene expression and memory performance in aged rats

Casoli, T., Di Stefano, G., Fattoretti, P., Giorgetti, B., Balietti, M., Lattanzio, F., Aicardi, G. & Platano, D., Mar 2012, In : Neurobiology of Aging. 33, 3

Research output: Contribution to journalArticle

Early impairment of long-term depression in the perirhinal cortex of a mouse model of Alzheimer's disease

Tamagnini, F., Burattini, C., Casoli, T., Balietti, M., Fattoretti, P. & Aicardi, G., Apr 1 2012, In : Rejuvenation Research. 15, 2, p. 231-234 4 p.

Research output: Contribution to journalArticle

Impairments of synaptic plasticity in aged animals and in animal models of Alzheimer's disease

Balietti, M., Tamagnini, F., Fattoretti, P., Burattini, C., Casoli, T., Platano, D., Lattanzio, F. & Aicardi, G., Apr 1 2012, In : Rejuvenation Research. 15, 2, p. 235-238 4 p.

Research output: Contribution to journalArticle

2010

A ketogenic diet increases succinic dehydrogenase (SDH) activity and recovers age-related decrease in numeric density of SDH-positive mitochondria in cerebellar Purkinje cells of late-adult rats

Balietti, M., Giorgetti, B., Di Stefano, G., Casoli, T., Platano, D., Solazzi, M., Bertoni-Freddari, C., Aicardi, G., Lattanzio, F. & Fattoretti, P., Feb 2010, In : Micron. 41, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

Decreased numeric density of succinic dehydrogenase-positive mitochondria in CA1 pyramidal neurons of 3xTg-AD mice

Fattoretti, P., Balietti, M., Casoli, T., Giorgetti, B., Di Stefano, G., Bertoni-Freddari, C., Lattanzio, F. & Sensi, S. L., Apr 1 2010, In : Rejuvenation Research. 13, 2-3, p. 144-147 4 p.

Research output: Contribution to journalArticle

Differences in gene expression in the hippocampus of aged rats are associated with better long-term memory performance in a passive avoidance test

Di Stefano, G., Casoli, T., Platano, D., Fattoretti, P., Balietti, M., Giorgetti, B., Bertoni-Freddari, C., Lattanzio, F. & Aicardi, G., Apr 1 2010, In : Rejuvenation Research. 13, 2-3, p. 224-228 5 p.

Research output: Contribution to journalArticle

Ketogenic diets: An historical antiepileptic therapy with promising potentialities for the aging brain

Balietti, M., Casoli, T., Di Stefano, G., Giorgetti, B., Aicardi, G. & Fattoretti, P., Jul 2010, In : Ageing Research Reviews. 9, 3, p. 273-279 7 p.

Research output: Contribution to journalArticle

Peripheral inflammatory biomarkers of Alzheimer's disease: The role of platelets

Casoli, T., Di Stefano, G., Balietti, M., Solazzi, M., Giorgetti, B. & Fattoretti, P., Oct 2010, In : Biogerontology. 11, 5, p. 627-633 7 p.

Research output: Contribution to journalArticle

2009

A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes: Potential protective role against apoptosis-induced heart failure

Balietti, M., Fattoretti, P., Giorgetti, B., Casoli, T., Di Stefano, G., Solazzi, M., Platano, D., Aicardi, G. & Bertoni-Freddari, C., Aug 2009, Annals of the New York Academy of Sciences. Vol. 1171. p. 377-384 8 p. (Annals of the New York Academy of Sciences; vol. 1171).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Effect of two medium chain triglycerides-supplemented diets on synaptic morphology in the cerebellar cortex of late-adult rats

Balietti, M., Fattoretti, P., Giorgetti, B., Casoli, T., Di Stefano, G., Platano, D., Aicardi, G., Lattanzio, F. & Bertoni-Freddari, C., Dec 2009, In : Microscopy Research and Technique. 72, 12, p. 933-938 6 p.

Research output: Contribution to journalArticle

Neuronal apoptosis in Alzheimer's disease: The role of age-related mitochondrial metabolic competence

Bertoni-Freddari, C., Fattoretti, P., Casoli, T., Di Stefano, G., Balietti, M., Giorgetti, B. & Perretta, G., Aug 2009, Annals of the New York Academy of Sciences. Vol. 1171. p. 18-24 7 p. (Annals of the New York Academy of Sciences; vol. 1171).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2008

Brain aging: The zinc connection

Bertoni-Freddari, C., Fattoretti, P., Casoli, T., Di Stefano, G., Giorgetti, B. & Balietti, M., May 2008, In : Experimental Gerontology. 43, 5, p. 389-393 5 p.

Research output: Contribution to journalArticle

Decreased presence of perforated synapses in a triple-transgenic mouse model of Alzheimer's disease

Bertoni-Freddari, C., Sensi, S. L., Giorgetti, B., Balietti, M., Di Stefano, G., Canzoniero, L. M. T., Casoli, T. & Fattoretti, P., Apr 1 2008, In : Rejuvenation Research. 11, 2, p. 309-313 5 p.

Research output: Contribution to journalArticle

Ketogenic diets cause opposing changes in synaptic morphology in CA1 hippocampus and dentate gyrus of late-adult rats

Balietti, M., Giorgetti, B., Fattoretti, P., Grossi, Y., Di Stefano, G., Casoli, T., Platano, D., Solazzi, M., Orlando, F., Aicardi, G. & Bertoni-Freddari, C., Jun 1 2008, In : Rejuvenation Research. 11, 3, p. 631-640 10 p.

Research output: Contribution to journalArticle

Platelet as a physiological model to investigate apoptotic mechanisms in Alzheimer β-amyloid peptide production

Casoli, T., Di Stefano, G., Giorgetti, B., Balietti, M., Recchioni, R., Moroni, F., Marcheselli, F., Bernardini, G., Fattoretti, P. & Bertoni-Freddari, C., Mar 2008, In : Mechanisms of Ageing and Development. 129, 3, p. 154-162 9 p.

Research output: Contribution to journalArticle

Selective decline of the metabolic competence of oversized synaptic mitochondria in the old monkey cerebellum

Bertoni-Freddari, C., Balietti, M., Giorgetti, B., Grossi, Y., Casoli, T., Di Stefano, G., Perretta, G. & Fattoretti, P., Apr 1 2008, In : Rejuvenation Research. 11, 2, p. 387-391 5 p.

Research output: Contribution to journalArticle

Synaptic remodeling in hippocampal CA1 region of aged rats correlates with better memory performance in passive avoidance test

Platano, D., Fattoretti, P., Balietti, M., Giorgetti, B., Casoli, T., Di Stefano, G., Bertoni-Freddari, C. & Aicardi, G., Apr 1 2008, In : Rejuvenation Research. 11, 2, p. 341-348 8 p.

Research output: Contribution to journalArticle

2007

Alterations of synaptic turnover rate in aging may trigger senile plaque formation and neurodegeneration

Bertoni-Freddari, C., Fattoretti, P., Giorgetti, B., Grossi, Y., Balietti, M., Casoli, T., Di Stefano, G. & Perretta, G., Jan 2007, Annals of the New York Academy of Sciences. Vol. 1096. p. 128-137 10 p. (Annals of the New York Academy of Sciences; vol. 1096).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Preservation of mitochondrial volume homeostasis at the early stages of age-related synaptic deterioration

Bertoni-Freddari, C., Fattoretti, P., Giorgetti, B., Grossi, Y., Balietti, M., Casoli, T., Di Stefano, G. & Perretta, G., Jan 2007, Annals of the New York Academy of Sciences. Vol. 1096. p. 138-146 9 p. (Annals of the New York Academy of Sciences; vol. 1096).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Release of β-amyloid from high-density platelets: Implications for Alzheimer's disease pathology

Casoli, T., Di Stefano, G., Giorgetti, B., Grossi, Y., Balietti, M., Fattoretti, P. & Bertoni-Freddari, C., Jan 2007, Annals of the New York Academy of Sciences. Vol. 1096. p. 170-178 9 p. (Annals of the New York Academy of Sciences; vol. 1096).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Synaptic and mitochondrial morphometry provides structural correlates of successful brain aging

Bertoni-Freddari, C., Fattoretti, P., Giorgetti, B., Grossi, Y., Balietti, M., Casoli, T., Di Stefano, G. & Perretta, G., Feb 2007, Annals of the New York Academy of Sciences. Vol. 1097. p. 51-53 3 p. (Annals of the New York Academy of Sciences; vol. 1097).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2006

Cytochemical estimation of cytochrome oxidase activity as a morphofunctional mitochondrial check-up

Bertoni-Freddari, C., Fattoretti, P., Giorgetti, B., Grossi, Y., Casoli, T., Di Stefano, G. & Balietti, M., Jun 2006, In : Rejuvenation Research. 9, 2, p. 202-206 5 p.

Research output: Contribution to journalArticle

Experimental apoptosis provides clues about the role of mitochondrial changes in neuronal death

Fattoretti, P., Bertoni-Freddari, C., Recchioni, R., Giorgetti, B., Balietti, M., Grossi, Y., Solazzi, M., Casoli, T., Di Stefano, G. & Marcheselli, F., Dec 2006, Annals of the New York Academy of Sciences. Vol. 1090. p. 79-88 10 p. (Annals of the New York Academy of Sciences; vol. 1090).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Level and distribution of microtubule-associated protein-2 (MAP2) as an index of dendritic structural dynamics

Di Stefano, G., Casoli, T., Fattoretti, P., Balietti, M., Grossi, Y., Giorgetti, B. & Bertoni-Freddari, C., Mar 2006, In : Rejuvenation Research. 9, 1, p. 94-98 5 p.

Research output: Contribution to journalArticle

Neurobiology of the Aging Brain

Bertoni-Freddari, C., Fattoretti, P., Casoli, T. & Di Stefano, G., 2006, Handbook of Models for Human Aging. Elsevier Inc., p. 485-506 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Reactive structural dynamics of synaptic mitochondria in ischemic delayed neuronal death

Bertoni-Freddari, C., Fattoretti, P., Casoli, T., Di Stefano, G., Solazzi, M., Perna, E. & De Angelis, C., Dec 2006, Annals of the New York Academy of Sciences. Vol. 1090. p. 26-34 9 p. (Annals of the New York Academy of Sciences; vol. 1090).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Structural synaptic remodeling in the perirhinal cortex of adult and old rats following object-recognition visual training

Platano, D., Bertoni-Freddari, C., Fattoretti, P., Giorgetti, B., Grossi, Y., Balietti, M., Casoli, T., Di Stefano, G. & Aicardi, G., Mar 2006, In : Rejuvenation Research. 9, 1, p. 102-106 5 p.

Research output: Contribution to journalArticle

Synaptic and mitochondrial physiopathologic changes in the aging nervous system and the role of zinc ion homeostasis

Bertoni-Freddari, C., Mocchegiani, E., Malavolta, M., Casoli, T., Di Stefano, G. & Fattoretti, P., Jun 2006, In : Mechanisms of Ageing and Development. 127, 6, p. 590-596 7 p.

Research output: Contribution to journalArticle

Synaptic pathology in the brain cortex of old monkeys as an early alteration in senile plaque formation

Bertoni-Freddari, C., Fattoretti, P., Giorgetti, B., Grossi, Y., Balietti, M., Casoli, T., Di Stefano, G. & Perretta, G., Mar 2006, In : Rejuvenation Research. 9, 1, p. 85-88 4 p.

Research output: Contribution to journalArticle

Testing mitochondrial metabolic competence by cytochrome oxidase preferential cytochemistry versus immunoreactivity of subunits I and IV

Fattoretti, P., Balietti, M., Giorgetti, B., Grossi, Y., Casoli, T., Di Stefano, G. & Bertoni-Freddari, C., Jun 2006, In : Rejuvenation Research. 9, 2, p. 215-218 4 p.

Research output: Contribution to journalArticle

2005

Modulating effects of nutrition on brain ageing

Bertoni-Freddari, C., Fattoretti, P., Casoli, T., Di Stefano, G., Solazzi, M., Giorgetti, B. & Balietti, M., 2005, In : NeuroImmune Biology. 4, C, p. 273-289 17 p.

Research output: Contribution to journalArticle

2004

Cytochrome oxidase activity in hippocampal synaptic mitochondria during aging: A quantitative cytochemical investigation

Bertoni-Freddari, C., Fattoretti, P., Giorgetti, B., Solazzi, M., Balietti, M., Casoli, T. & Di Stefano, G., 2004, In : Annals of the New York Academy of Sciences. 1019, p. 33-36 4 p.

Research output: Contribution to journalArticle

Decay of mitochondrial metabolic competence in the aging cerebellum

Bertoni-Freddari, C., Fattoretti, P., Giorgetti, B., Solazzi, M., Balietti, M., Di Stefano, G. & Casoli, T., 2004, In : Annals of the New York Academy of Sciences. 1019, p. 29-32 4 p.

Research output: Contribution to journalArticle

Metallothionein isoforms (I + II and III) and interleukin-6 in the hippocampus of old rats: May their concomitant increments lead to neurodegeneration?

Mocchegiani, E., Giacconi, R., Fattoretti, P., Casoli, T., Cipriano, C., Muti, E., Malavolta, M., DiStefano, G. & Bertoni-Freddari, C., Mar 15 2004, In : Brain Research Bulletin. 63, 2, p. 133-142 10 p.

Research output: Contribution to journalArticle

2003