1993 …2019

Research output per year

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Research Output

2019

A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing

Angiolini, F., Belloni, E., Giordano, M., Campioni, M., Forneris, F., Paronetto, M. P., Lupia, M., Brandas, C., Pradella, D., Di Matteo, A., Giampietro, C., Jodice, G., Luise, C., Bertalot, G., Freddi, S., Malinverno, M., Irimia, M., Moulton, J. D., Summerton, J., Chiapparino, A. & 7 others, Ghilardi, C., Giavazzi, R., Nyqvist, D., Gabellini, D., Dejana, E., Cavallaro, U. & Ghigna, C., Mar 2019, In : eLife. 8, e44305.

Research output: Contribution to journalArticle

Open Access

Number and brightness analysis reveals that NCAM and FGF2 elicit different assembly and dynamics of FGFR1 in live cells

Zamai, M., Trullo, A., Giordano, M., Corti, V., Cuesta, E. A., Francavilla, C., Cavallaro, U. & Caiolfa, V. R., Jan 1 2019, In : Journal of Cell Science. 132, 1, jcs220624.

Research output: Contribution to journalArticle

Open Access
2018

CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells

Lupia, M., Angiolini, F., Bertalot, G., Freddi, S., Sachsenmeier, K. F., Chisci, E., Kutryb-Zajac, B., Confalonieri, S., Smolenski, R. T., Giovannoni, R., Colombo, N., Bianchi, F. & Cavallaro, U., Apr 10 2018, In : Stem Cell Reports. 10, 4, p. 1412-1425 14 p.

Research output: Contribution to journalArticle

CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells

Lupia, M., Angiolini, F., Bertalot, G., Freddi, S., Sachsenmeier, K. F., Chisci, E., Kutryb-Zajac, B., Confalonieri, S., Smolenski, R. T., Giovannoni, R., Colombo, N., Bianchi, F. & Cavallaro, U., Apr 10 2018, In : Stem Cell Reports. 10, 4, p. 1412-1425 14 p.

Research output: Contribution to journalArticle

Extensive and systematic rewiring of histone post-translational modifications in cancer model systems

Noberini, R., Osti, D., Miccolo, C., Richichi, C., Lupia, M., Corleone, G., Hong, S. P., Colombo, P., Pollo, B., Fornasari, L., Pruneri, G., Magnani, L., Cavallaro, U., Chiocca, S., Minucci, S., Pelicci, G. & Bonaldi, T., Jan 1 2018, In : Nucleic Acids Research. 46, 8, p. 3817-3832 16 p.

Research output: Contribution to journalArticle

Extensive and systematic rewiring of histone post-translational modifications in cancer model systems

Noberini, R., Osti, D., Miccolo, C., Richichi, C., Lupia, M., Corleone, G., Hong, S-P., Colombo, P., Pollo, B., Fornasari, L., Pruneri, G., Magnani, L., Cavallaro, U., Chiocca, S., Minucci, S., Pelicci, G. & Bonaldi, T., May 4 2018, In : Nucleic Acids Research. 46, 8, p. 3817-3832 16 p.

Research output: Contribution to journalArticle

Platinum sensitivity and DNA repair in a recently established panel of patient-derived ovarian carcinoma xenografts

Guffanti, F., Fratelli, M., Ganzinelli, M., Bolis, M., Ricci, F., Bizzaro, F., Chilà, R., Sina, F. P., Fruscio, R., Lupia, M., Cavallaro, U., Cappelletti, M. R., Generali, D., Giavazzi, R. & Damia, G., May 15 2018, In : Oncotarget. 9, 37, p. 24707-24717 11 p.

Research output: Contribution to journalArticle

VE-cadherin-mediated epigenetic regulation of endothelial gene expression

Morini, M. F., Giampietro, C., Corada, M., Pisati, F., Lavarone, E., Cunha, S. I., Conze, L. L., O'Reilly, N., Joshi, D., Kjaer, S., George, R., Nye, E., Ma, A., Jin, J., Mitter, R., Lupia, M., Cavallaro, U., Pasini, D., Calado, D. P., Dejana, E. & 1 others, Taddei, A., Jan 1 2018, In : Circulation Research. 122, 2, p. 231-245 15 p.

Research output: Contribution to journalArticle

2017

Ovarian cancer stem cells: Still an elusive entity?

Lupia, M. & Cavallaro, U., Mar 20 2017, In : Molecular Cancer. 16, 1, 64.

Research output: Contribution to journalReview article

Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer

Francavilla, C., Lupia, M., Tsafou, K., Villa, A., Kowalczyk, K., Rakownikow Jersie-Christensen, R., Bertalot, G., Confalonieri, S., Brunak, S., Jensen, L. J., Cavallaro, U. & Olsen, J. V., Mar 28 2017, In : Cell Reports. 18, 13, p. 3242-3256 15 p.

Research output: Contribution to journalArticle

The pleiotropic role of L1CAM in tumor vasculature

Angiolini, F. & Cavallaro, U., Feb 1 2017, In : International Journal of Molecular Sciences. 18, 2, 254.

Research output: Contribution to journalReview article

2016

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain

Wollscheid, H. P., Biancospino, M., He, F., Magistrati, E., Molteni, E., Lupia, M., Soffientini, P., Rottner, K., Cavallaro, U., Pozzoli, U., Mapelli, M., Walters, K. J. & Polo, S., Apr 5 2016, In : Nature Structural and Molecular Biology. 23, 4, p. 300-308 9 p.

Research output: Contribution to journalArticle

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain

Wollscheid, H. P., Biancospino, M., He, F., Magistrati, E., Molteni, E., Lupia, M., Soffientini, P., Rottner, K., Cavallaro, U., Pozzoli, U., Mapelli, M., Walters, K. J. & Polo, S., Apr 5 2016, In : Nature Structural and Molecular Biology. 23, 4, p. 300-308 9 p.

Research output: Contribution to journalArticle

L1 in tumor vasculature

Cavallaro, U., Mar 15 2016, In : Oncotarget. 7, 11, p. 11744-11745 2 p.

Research output: Contribution to journalArticle

2015
2014

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization

Magrini, E., Villa, A., Angiolini, F., Doni, A., Mazzarol, G., Rudini, N., Maddaluno, L., Komuta, M., Topal, B., Prenen, H., Schachner, M., Confalonieri, S., Dejana, E., Bianchi, F., Mazzone, M. & Cavallaro, U., Oct 1 2014, In : Journal of Clinical Investigation. 124, 10, p. 4335-4350 16 p.

Research output: Contribution to journalArticle

Erratum: Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization (Journal of Clinical Investigation (2014) 124:11 (5085) DOI:10.1172/JCI79236)

Magrini, E., Villa, A., Angiolini, F., Doni, A., Mazzarol, G., Rudini, N., Maddaluno, L., Komuta, M., Topal, B., Prenen, H., Schachner, M., Confalonieri, S., Dejana, E., Bianchi, F., Mazzone, M. & Cavallaro, U., Nov 3 2014, In : Journal of Clinical Investigation. 124, 11, p. 5085 1 p.

Research output: Contribution to journalArticle

Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24-25 June 2014, Milan

Bouche, G., André, N., Banavali, S., Berthold, F., Berruti, A., Bocci, G., Brandi, G., Cavallaro, U., Cinieri, S., Colleoni, M., Curigliano, G., Di Desidero, T., Eniu, A., Fazio, N., Kerbel, R., Hutchinson, L., Ledzewicz, U., Munzone, E., Pasquier, E., Scharovsky, O. G. & 4 others, Shaked, Y., Štěrba, J., Villalba, M. & Bertolini, F., Sep 9 2014, In : ecancermedicalscience. 8, 463.

Research output: Contribution to journalArticle

2013

Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs

Francavilla, C., Rigbolt, K. G., Emdal, K., Carraro, G., Vernet, E., Bekker-Jensen, D., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, J., Sep 26 2013, In : Molecular Cell. 51, 6, p. 707-722 16 p.

Research output: Contribution to journalArticle

Multivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells

Cattaruzza, S., Ozerdem, U., Denzel, M., Ranscht, B., Bulian, P., Cavallaro, U., Zanocco, D., Colombatti, A., Stallcup, W. B. & Perris, R., Apr 2013, In : Angiogenesis. 16, 2, p. 309-327 19 p.

Research output: Contribution to journalArticle

2012

Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells

Giampietro, C., Taddei, A., Corada, M., Sarra-Ferraris, G. M., Alcalay, M., Cavallaro, U., Orsenigo, F., Lampugnani, M. G. & Dejana, E., Mar 1 2012, In : Blood. 119, 9, p. 2159-2170 12 p.

Research output: Contribution to journalArticle

2011

Adhesion molecule signalling: Not always a sticky business

Cavallaro, U. & Dejana, E., Mar 2011, In : Nature Reviews Molecular Cell Biology. 12, 3, p. 189-197 9 p.

Research output: Contribution to journalArticle

Single-domain antibodies that compete with the natural ligand fibroblast growth factor block the internalization of the fibroblast growth factor receptor 1

Veggiani, G., Ossolengo, G., Aliprandi, M., Cavallaro, U. & de Marco, A., May 20 2011, In : Biochemical and Biophysical Research Communications. 408, 4, p. 692-696 5 p.

Research output: Contribution to journalArticle

The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling

Zecchini, S., Bombardelli, L., Decio, A., Bianchi, M., Mazzarol, G., Sanguineti, F., Aletti, G., Maddaluno, L., Berezin, V., Bock, E., Casadio, C., Viale, G., Colombo, N., Giavazzi, R. & Cavallaro, U., Aug 2011, In : EMBO Molecular Medicine. 3, 8, p. 480-494 15 p.

Research output: Contribution to journalArticle

The interplay between NCAM and FGFR signalling underlies ovarian cancer progression

Colombo, N. & Cavallaro, U., Oct 20 2011, In : ecancermedicalscience. 5, 1, 226.

Research output: Contribution to journalArticle

2010

Immunoglobulin-like cell adhesion molecules: Novel signaling players in epithelial ovarian cancer

Bombardelli, L. & Cavallaro, U., May 2010, In : International Journal of Biochemistry and Cell Biology. 42, 5, p. 590-594 5 p.

Research output: Contribution to journalArticle

Inactivation of junctional adhesion molecule-A enhances antitumoral immune response by promoting dendritic cell and T lymphocyte infiltration

Murakami, M., Francavilla, C., Torselli, I., Corada, M., Maddaluno, L., Sica, A., Matteoli, G., Iliev, I. D., Mantovani, A., Rescigno, M., Cavallaro, U. & Dejana, E., Mar 1 2010, In : Cancer Research. 70, 5, p. 1759-1765 7 p.

Research output: Contribution to journalArticle

Neural Cell adhesion molecule in cancer: Expression and mechanisms

Zecchini, S. & Cavallaro, U., 2010, Advances in Experimental Medicine and Biology. Vol. 663. p. 319-333 15 p. (Advances in Experimental Medicine and Biology; vol. 663).

Research output: Chapter in Book/Report/Conference proceedingChapter

2009

The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells

Maddaluno, L., Verbrugge, S. E., Martinoli, C., Matteoli, G., Chiavelli, A., Zeng, Y., Williams, E. D., Rescigno, M. & Cavallaro, U., Mar 16 2009, In : Journal of Experimental Medicine. 206, 3, p. 623-635 13 p.

Research output: Contribution to journalArticle

The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking

Francavilla, C., Cattaneo, P., Berezin, V., Bock, E., Ami, D., De Marco, A., Christofori, G. & Cavallaro, U., Dec 28 2009, In : Journal of Cell Biology. 187, 7, p. 1101-1116 16 p.

Research output: Contribution to journalArticle

The functional role of cell adhesion molecules in tumor angiogenesis

Francavilla, C., Maddaluno, L. & Cavallaro, U., Oct 2009, In : Seminars in Cancer Biology. 19, 5, p. 298-309 12 p.

Research output: Contribution to journalArticle

2008

Adhesion molecules in the vascular cell cross-talk

Cavallaro, U., 2008, Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy. Springer Berlin Heidelberg, p. 289-308 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium

Zecchini, S., Bianchi, M., Colombo, N., Fasani, R., Goisis, G., Casadio, C., Viale, G., Liu, J., Herlyn, M., Godwin, A. K., Nuciforo, P. G. & Cavallaro, U., Feb 15 2008, In : Cancer Research. 68, 4, p. 1110-1118 9 p.

Research output: Contribution to journalArticle

2007

Increased tumor cell dissemination and cellular senescence in the absence of β1-integrin function

Kren, A., Baeriswyl, V., Lehembre, F., Wunderlin, C., Strittmatter, K., Antoniadis, H., Fässler, R., Cavallaro, U. & Christofori, G., Jun 20 2007, In : EMBO Journal. 26, 12, p. 2832-2842 11 p.

Research output: Contribution to journalArticle

Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor

Francavilla, C., Loeffler, S., Piccini, D., Kren, A., Christofori, G. & Cavallaro, U., Dec 15 2007, In : Journal of Cell Science. 120, 24, p. 4388-4394 7 p.

Research output: Contribution to journalArticle

2006

Endothelial cadherins and tumor angiogenesis

Cavallaro, U., Liebner, S. & Dejana, E., Mar 10 2006, In : Experimental Cell Research. 312, 5, p. 659-667 9 p.

Research output: Contribution to journalArticle

The multiple languages of endothelial cell-to-cell communication

Liebner, S., Cavallaro, U. & Dejana, E., Jul 2006, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 26, 7, p. 1431-1438 8 p.

Research output: Contribution to journalArticle

2004

Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

Cavallaro, U. & Christofori, G., Feb 2004, In : Nature Reviews Cancer. 4, 2, p. 118-132 15 p.

Research output: Contribution to journalArticle

Loss of neural cell adhesion molecule induces tumor metastasis by up-regulating lymphangiogenesis

Crnic, I., Strittmatter, K., Cavallaro, U., Kopfstein, L., Jussila, L., Alitalo, K. & Christofori, G., Dec 1 2004, In : Cancer Research. 64, 23, p. 8630-8638 9 p.

Research output: Contribution to journalArticle

Multitasking in tumor progression: Signaling functions of cell adhesion molecules

Cavallaro, U. & Christofori, G., 2004, In : Annals of the New York Academy of Sciences. 1014, p. 58-66 9 p.

Research output: Contribution to journalArticle

N-cadherin as an invasion promoter: A novel target for antitumor therapy?

Cavallaro, U., Dec 2004, In : Current Opinion in Investigational Drugs. 5, 12, p. 1274-1278 5 p.

Research output: Contribution to journalArticle

2003

Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells

Galbiati, F., Polastri, L., Thorens, B., Dupraz, P., Fiorina, P., Cavallaro, U., Christofori, G. & Davalli, A. M., May 1 2003, In : Endocrinology. 144, 5, p. 1832-1841 10 p.

Research output: Contribution to journalArticle

2002

Antitumorigenic and antiinsulinogenic effects of calcitriol on insulinoma cells and solid β-cell tumors

Galbiati, F., Polastri, L., Gregori, S., Freschi, M., Casorati, M., Cavallaro, U. G. O., Fiorina, P., Bertuzzi, F., Zerbi, A., Pozza, G., Adorini, L., Folli, F., Christofori, G. & Davalli, A. M., Oct 1 2002, In : Endocrinology. 143, 10, p. 4018-4030 13 p.

Research output: Contribution to journalArticle

Cadherins and the tumour progression: Is it all in a switch?

Cavallaro, U., Schaffhauser, B. & Christofori, G., Feb 25 2002, In : Cancer Letters. 176, 2, p. 123-128 6 p.

Research output: Contribution to journalArticle

Differential response to Tat and FGF-2 of two novel clonal populations derived from murine Kaposi-like lesions developing in Tat transgenic mice

Wu, Z., Mariotti, M., Cavallaro, U., Soria, M. R. & Maier, J. A. M., 2002, In : Microvascular Research. 63, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

2001

Cell adhesion in tumor invasion and metastasis: Loss of the glue is not enough

Cavallaro, U. & Christofori, G., Nov 30 2001, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1552, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

FGF-2 promotes disassembly of actin cytoskeleton and shape changes in murine vascular cells

Cavallaro, U., Perilli, A., Castelli, V., Pepper, M. S. & Soria, M. R., 2001, In : Microvascular Research. 61, 2, p. 211-214 4 p.

Research output: Contribution to journalArticle

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

Cavallaro, U., Niedermeyer, J., Fuxa, M. & Christofori, G., 2001, In : Nature Cell Biology. 3, 7, p. 650-657 8 p.

Research output: Contribution to journalArticle

Response of bovine endothelial cells to FGF-2 and VEGF is dependent on their site of origin: Relevance to the regulation of angiogenesis

Cavallaro, U., Tenan, M., Castelli, V., Perilli, A., Maggiano, N., Van Meir, E. G., Montesano, R., Soria, M. R. & Pepper, M. S., 2001, In : Journal of Cellular Biochemistry. 82, 4, p. 619-633 15 p.

Research output: Contribution to journalArticle