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2019

Baseline and Postoperative C-reactive Protein Levels Predict Long-Term Survival After Lung Metastasectomy

Pastorino, U., Morelli, D., Leuzzi, G., Rolli, L., Suatoni, P., Taverna, F., Bertocchi, E., Boeri, M., Sozzi, G., Cantarutti, A., Corrao, G. & Gronchi, A., Mar 15 2019, In : Annals of Surgical Oncology. 26, 3, p. 869-875 7 p.

Research output: Contribution to journalArticle

Circulating mir-320a promotes immunosuppressive macrophages M2 phenotype associated with lung cancer risk

Fortunato, O., Borzi, C., Milione, M., Centonze, G., Conte, D., Boeri, M., Verri, C., Moro, M., Facchinetti, F., Andriani, F., Roz, L., Caleca, L., Huber, V., Cova, A., Camisaschi, C., Castelli, C., Cancila, V., Tripodo, C., Pastorino, U. & Sozzi, G., Jun 1 2019, In : International Journal of Cancer. 144, 11, p. 2746-2761 16 p.

Research output: Contribution to journalArticle

Open Access

c-Myc shuttled by tumour-derived extracellular vesicles promotes lung bronchial cell proliferation through miR-19b and miR-92a

Borzi, C., Calzolari, L., Ferretti, A. M., Caleca, L., Pastorino, U., Sozzi, G. & Fortunato, O., Oct 1 2019, In : Cell Death and Disease. 10, 10, 759.

Research output: Contribution to journalArticle

Open Access

Coated cationic lipid-nanoparticles entrapping miR-660 inhibit tumor growth in patient-derived xenografts lung cancer models

Moro, M., Di Paolo, D., Milione, M., Centonze, G., Bornaghi, V., Borzi, C., Gandellini, P., Perri, P., Pastorino, U., Ponzoni, M., Sozzi, G. & Fortunato, O., Aug 28 2019, In : Journal of Controlled Release. 308, p. 44-56 13 p.

Research output: Contribution to journalArticle

Open Access

Comparison of ultra-low dose chest CT scanning protocols for the detection of pulmonary nodules: a phantom study

Milanese, G., Silva, M., Frauenfelder, T., Eberhard, M., Sabia, F., Martini, C., Marchianò, A., Prokop, M., Sverzellati, N. & Pastorino, U., Oct 1 2019, In : Tumori. 105, 5, p. 394-403 10 p.

Research output: Contribution to journalArticle

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

Alcala, N., Leblay, N., Gabriel, A. A. G., Mangiante, L., Hervas, D., Giffon, T., Sertier, A. S., Ferrari, A., Derks, J., Ghantous, A., Delhomme, T. M., Chabrier, A., Cuenin, C., Abedi-Ardekani, B., Boland, A., Olaso, R., Meyer, V., Altmuller, J., Le Calvez-Kelm, F., Durand, G. & 50 others, Voegele, C., Boyault, S., Moonen, L., Lemaitre, N., Lorimier, P., Toffart, A. C., Soltermann, A., Clement, J. H., Saenger, J., Field, J. K., Brevet, M., Blanc-Fournier, C., Galateau-Salle, F., Le Stang, N., Russell, P. A., Wright, G., Sozzi, G., Pastorino, U., Lacomme, S., Vignaud, J. M., Hofman, V., Hofman, P., Brustugun, O. T., Lund-Iversen, M., Thomas de Montpreville, V., Muscarella, L. A., Graziano, P., Popper, H., Stojsic, J., Deleuze, J. F., Herceg, Z., Viari, A., Nuernberg, P., Pelosi, G., Dingemans, A. M. C., Milione, M., Roz, L., Brcic, L., Volante, M., Papotti, M. G., Caux, C., Sandoval, J., Hernandez-Vargas, H., Brambilla, E., Speel, E. J. M., Girard, N., Lantuejoul, S., McKay, J. D., Foll, M. & Fernandez-Cuesta, L., Dec 1 2019, In : Nature Communications. 10, 1, 3407.

Research output: Contribution to journalArticle

Open Access

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

Alcala, N., Leblay, N., Gabriel, A. A. G., Mangiante, L., Hervas, D., Giffon, T., Sertier, A. S., Ferrari, A., Derks, J., Ghantous, A., Delhomme, T. M., Chabrier, A., Cuenin, C., Abedi-Ardekani, B., Boland, A., Olaso, R., Meyer, V., Altmuller, J., Le Calvez-Kelm, F., Durand, G. & 30 others, Voegele, C., Boyault, S., Moonen, L., Lemaitre, N., Lorimier, P., Toffart, A. C., Soltermann, A., Clement, J. H., Saenger, J., Field, J. K., Brevet, M., Blanc-Fournier, C., Galateau-Salle, F., Le Stang, N., Russell, P. A., Wright, G., Sozzi, G., Pastorino, U., Lacomme, S., Vignaud, J. M., Hofman, V., Hofman, P., Brustugun, O. T., Lund-Iversen, M., Muscarella, L. A., Graziano, P., Pelosi, G., Milione, M., Roz, L. & Brambilla, E., 2019, In : Nature Communications. 10, 1

Research output: Contribution to journalArticle

Oral maintenance metronomic vinorelbine versus best supportive care in advanced non-small-cell lung cancer after platinum-based chemotherapy: The MA.NI.LA. multicenter, randomized, controlled, phase II trial

Platania, M., Pasini, F., Porcu, L., Boeri, M., Verderame, F., Modena, Y., Del Conte, A., Nichetti, F., Garassino, M. C., Martinetti, A., Sottotetti, E., Cavanna, L., Vattemi, E., Pozzessere, D., Bertolini, A., Irtelli, L., Verri, C., Sozzi, G., Proto, C., Pastorino, U. & 12 others, Torri, V., Fraccon, A. P., Spinnato, F., Signorelli, D., Lo Russo, G., Tuzi, A., Gallucci, R., Cinieri, S., Mencoboni, M., Antonelli, P., Giacomelli, L. & de Braud, F., Jun 2019, In : Lung Cancer. 132, p. 17-23 7 p.

Research output: Contribution to journalArticle

Prolonged lung cancer screening reduced 10-year mortality in the MILD trial: new confirmation of lung cancer screening efficacy

Pastorino, U., Silva, M., Sestini, S., Sabia, F., Boeri, M., Cantarutti, A., Sverzellati, N., Sozzi, G., Corrao, G. & Marchianò, A., Jul 1 2019, In : Annals of Oncology. 30, 7, p. 1162-1169 8 p., mdz117.

Research output: Contribution to journalArticle

Open Access

Sulphurous thermal water inhalation impacts respiratory metabolic parameters in heavy smokers

Carubbi, C., Masselli, E., Calabrò, E., Bonati, E., Galeone, C., Andreoli, R., Goldoni, M., Corradi, M., Sverzellati, N., Pozzi, G., Banchini, A., Pastorino, U. & Vitale, M., Sep 15 2019, In : International Journal of Biometeorology. 63, 9, p. 1209-1216 8 p.

Research output: Contribution to journalArticle

Ten-year results of the Multicentric Italian Lung Detection trial demonstrate the safety and efficacy of biennial lung cancer screening

Pastorino, U., Sverzellati, N., Sestini, S., Silva, M., Sabia, F., Boeri, M., Cantarutti, A., Sozzi, G., Corrao, G. & Marchianò, A., Sep 2019, In : European Journal of Cancer. 118, p. 142-148 7 p.

Research output: Contribution to journalArticle

Open Access

Toll-like receptor 3 as a new marker to detect high risk early stage Non-Small-Cell Lung Cancer patients

Bianchi, F., Milione, M., Casalini, P., Centonze, G., Le Noci, V. M., Storti, C., Alexiadis, S., Truini, M., Sozzi, G., Pastorino, U., Balsari, A., Tagliabue, E. & Sfondrini, L., Dec 1 2019, In : Scientific Reports. 9, 1, 14288.

Research output: Contribution to journalArticle

Open Access
2018

A classification prognostic score to predict OS in stage IV well-differentiated neuroendocrine tumors

NEPscore Working Group, Jun 2018, In : Endocrine-Related Cancer. 25, 6, p. 607-618 12 p.

Research output: Contribution to journalArticle

A classification prognostic score to predict OS in stage IV well-differentiated neuroendocrine tumors

Pusceddu, S., Barretta, F., Trama, A., Botta, L., Milione, M., Buzzoni, R., De Braud, F., Mazzaferro, V., Pastorino, U., Seregni, E., Mariani, L., Gatta, G., Di Bartolomeo, M., Femia, D., Prinzi, N., Coppa, J., Panzuto, F., Antonuzzo, L., Bajetta, E., Pia Brizzi, M. & 46 others, Campana, D., Catena, L., Comber, H., Dwane, F., Fazio, N., Faggiano, A., Giuffrida, D., Henau, K., Ibrahim, T., Marconcini, R., Massironi, S., Žakelj, M. P., Spada, F., Tafuto, S., Van Eycken, E., Van Der Zwan, J. M., Žagar, T., Giacomelli, L., Miceli, R., Francesca, A., Alberto, B., Rossana, B., Nicole, B., Sara, C., Carolina, C., Federica, C., Carlo, C., Francesca, C., Marilina, D., Vittoria, D. M., Chiara, D. D., Paola, E., Anna, L. S., Gabriele, L., Giuseppe, L. R., Federico, N., Alessandra, R., Vittorio, P., Paola, R., Maria, R., Sabine, S., Martina, T., Boukje, V. D., Otto, V., Claudio, V. & Group, NEP. W., 2018, In : Endocrine-Related Cancer. 25, 6, p. 607-618 12 p.

Research output: Contribution to journalArticle

A classification prognostic score to predict OS in stage IV well-differentiated neuroendocrine tumors

Pusceddu, S., Barretta, F., Trama, A., Botta, L., Milione, M., Buzzoni, R., De Braud, F., Mazzaferro, V., Pastorino, U., Seregni, E., Mariani, L., Gatta, G., Di Bartolomeo, M., Femia, D., Prinzi, N., Coppa, J., Panzuto, F., Antonuzzo, L., Bajetta, E., Pia Brizzi, M. & 46 others, Campana, D., Catena, L., Comber, H., Dwane, F., Fazio, N., Faggiano, A., Giuffrida, D., Henau, K., Ibrahim, T., Marconcini, R., Massironi, S., Žakelj, M. P., Spada, F., Tafuto, S., Van Eycken, E., Van Der Zwan, J. M., Žagar, T., Giacomelli, L., Miceli, R., Francesca, A., Alberto, B., Rossana, B., Nicole, B., Sara, C., Carolina, C., Federica, C., Carlo, C., Francesca, C., Marilina, D., Vittoria, D. M., Chiara, D. D., Paola, E., Anna, L. S., Gabriele, L., Giuseppe, L. R., Federico, N., Alessandra, R., Vittorio, P., Paola, R., Maria, R., Sabine, S., Martina, T., Boukje, V. D., Otto, V., Claudio, V. & Group, NEP. W., 2018, In : Endocrine-Related Cancer. 25, 6, p. 607-618 12 p.

Research output: Contribution to journalArticle

A classification prognostic score to predict OS in stage IV well-differentiated neuroendocrine tumors

NEPscore Working Group, Jun 1 2018, In : Endocrine-Related Cancer. 25, 6, p. 607-618 12 p.

Research output: Contribution to journalArticle

Automatic segmentation of the solid core and enclosed vessels in subsolid pulmonary nodules

Charbonnier, J-P., Chung, K., Scholten, E. T., van Rikxoort, E. M., Jacobs, C., Sverzellati, N., Silva, M., Pastorino, U., van Ginneken, B. & Ciompi, F., Jan 12 2018, In : Scientific Reports. 8, 1, p. 646

Research output: Contribution to journalArticle

Best practices for the management of thymic epithelial tumors: A position paper by the Italian collaborative group for ThYmic MalignanciEs (TYME)

collaborators, TYME. N., Imbimbo, M., Ottaviano, M., Vitali, M., Fabbri, A., Leuzzi, G., Fiore, M., Franceschini, D., Pasello, G., Perrino, M., Schiavon, M., Pruneri, G., Dei Tos, A. P., Sangalli, C., Garassino, M. C., Berardi, R., Alessi, A., Calareso, G., Petrini, I., Scorsetti, M. & 13 others, Scotti, V., Rosso, L., Rea, F., Pastorino, U., Casali, P. G., Ramella, S., Ricardi, U., Abate-Daga, L., Torri, V., Trama, A., Palmieri, G., Marino, M. & Zucali, P. A., Dec 1 2018, In : Cancer Treatment Reviews. 71, p. 76-87 12 p.

Research output: Contribution to journalArticle

Best practices for the management of thymic epithelial tumors: A position paper by the Italian collaborative group for ThYmic MalignanciEs (TYME)

Imbimbo, M., Ottaviano, M., Vitali, M., Fabbri, A., Leuzzi, G., Fiore, M., Franceschini, D., Pasello, G., Perrino, M., Schiavon, M., Pruneri, G., Dei Tos, A. P., Sangalli, C., Garassino, M. C., Berardi, R., Alessi, A., Calareso, G., Petrini, I., Scorsetti, M., Scotti, V. & 12 others, Rosso, L., Rea, F., Pastorino, U., Casali, P. G., Ramella, S., Ricardi, U., Abate-Daga, L., Torri, V., Trama, A., Palmieri, G., Marino, M. & Zucali, P. A., 2018, In : Cancer Treatment Reviews. 71, p. 76-87 12 p.

Research output: Contribution to journalArticle

Best practices for the management of thymic epithelial tumors: A position paper by the Italian collaborative group for ThYmic MalignanciEs (TYME)

Imbimbo, M., Ottaviano, M., Vitali, M., Fabbri, A., Leuzzi, G., Fiore, M., Franceschini, D., Pasello, G., Perrino, M., Schiavon, M., Pruneri, G., Dei Tos, A. P., Sangalli, C., Garassino, M. C., Berardi, R., Alessi, A., Calareso, G., Petrini, I., Scorsetti, M., Scotti, V. & 13 others, Rosso, L., Rea, F., Pastorino, U., Casali, P. G., Ramella, S., Ricardi, U., Abate-Daga, L., Torri, V., Trama, A., Palmieri, G., Marino, M., Zucali, P. A. & collaborators, TYME. N., Dec 2018, In : Cancer Treatment Reviews. 71, p. 76-87 12 p.

Research output: Contribution to journalArticle

Detection of Subsolid Nodules in Lung Cancer Screening: Complementary Sensitivity of Visual Reading and Computer-Aided Diagnosis

Silva, M., Schaefer-Prokop, C. M., Jacobs, C., Capretti, G., Ciompi, F., van Ginneken, B., Pastorino, U. & Sverzellati, N., Aug 2018, In : Investigative Radiology. 53, 8, p. 441-449 9 p.

Research output: Contribution to journalArticle

Inflammatory status and lung function predict mortality in lung cancer screening participants

Pastorino, U., Morelli, D., Marchianò, A., Sestini, S., Suatoni, P., Taverna, F., Boeri, M., Sozzi, G., Cantarutti, A. & Corrao, G., Jul 2018, In : European Journal of Cancer Prevention. 27, 4, p. 289-295 7 p.

Research output: Contribution to journalArticle

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

George, J., Walter, V., Peifer, M., Alexandrov, L. B., Seidel, D., Leenders, F., Maas, L., Müller, C., Dahmen, I., Delhomme, T. M., Ardin, M., Leblay, N., Byrnes, G., Sun, R., De Reynies, A., McLeer-Florin, A., Bosco, G., Malchers, F., Menon, R., Altmüller, J. & 42 others, Becker, C., Nürnberg, P., Achter, V., Lang, U., Schneider, P. M., Bogus, M., Soloway, M. G., Wilkerson, M. D., Cun, Y., McKay, J. D., Moro-Sibilot, D., Brambilla, C. G., Lantuejoul, S., Lemaitre, N., Soltermann, A., Weder, W., Tischler, V., Brustugun, O. T., Lund-Iversen, M., Helland, Å., Solberg, S., Ansén, S., Wright, G., Solomon, B., Roz, L., Pastorino, U., Petersen, I., Clement, J. H., Sänger, J., Wolf, J., Vingron, M., Zander, T., Perner, S., Travis, W. D., Haas, S. A., Olivier, M., Foll, M., Büttner, R., Hayes, D. N., Brambilla, E., Fernandez-Cuesta, L. & Thomas, R. K., 2018, In : Nature Communications. 9, 1

Research output: Contribution to journalArticle

Long-Term Active Surveillance of Screening Detected Subsolid Nodules is a Safe Strategy to Reduce Overtreatment

Silva, M., Prokop, M., Jacobs, C., Capretti, G., Sverzellati, N., Ciompi, F., van Ginneken, B., Schaefer-Prokop, C. M., Galeone, C., Marchianò, A. & Pastorino, U., Oct 2018, In : Journal of Thoracic Oncology. 13, 10, p. 1454-1463 10 p.

Research output: Contribution to journalArticle

p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression

Amelio, I., Mancini, M., Petrova, V., Cairns, R. A., Vikhreva, P., Nicolai, S., Marini, A., Antonov, A. A., Le Quesne, J., Baena Acevedo, J. D., Dudek, K., Sozzi, G., Pastorino, U., Knight, R. A., Mak, T. W. & Melino, G., Nov 13 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 46, p. E10869-E10878

Research output: Contribution to journalArticle

Thirty-day mortality and five-year survival in thoracic surgery: “Real-world” assessment of outcomes from a single-institution audit

Cantarutti, A., Galeone, C., Leuzzi, G., Bertocchi, E., Pomponi, G., Langer, M., Mazzaferro, V., Galmozzi, G., Apolone, G., Corrao, G. & Pastorino, U., 2018, In : Tumori. 104, 2, p. 96-104 9 p.

Research output: Contribution to journalArticle

Unexpected postpneumonectomy exertion-induced acute right heart failure

Colombo, J., Arendar, I., Pastorino, U. & Codazzi, D., Nov 28 2018, In : Tumori. p. 300891618812682

Research output: Contribution to journalArticle

2017

Autologous fat tissue grafting improves pulmonary healing after laser metastasectomy

Furia, S., Cadenelli, P., Andriani, F., Scanagatta, P., Duranti, L., Spano, A., Galeone, C., Porcu, L. & Pastorino, U., Dec 1 2017, In : European Journal of Surgical Oncology. 43, 12, p. 2315-2323 9 p.

Research output: Contribution to journalArticle

Baseline and postoperative C-reactive protein levels predict mortality in operable lung cancer

Pastorino, U., Morelli, D., Leuzzi, G., Gisabella, M., Suatoni, P., Taverna, F., Bertocchi, E., Boeri, M., Sozzi, G., Cantarutti, A. & Corrao, G., 2017, In : European Journal of Cancer. 79, p. 90-97 8 p.

Research output: Contribution to journalArticle

Early Effector T Lymphocytes Coexpress Multiple Inhibitory Receptors in Primary Non-Small Cell Lung Cancer.

Tassi, E., Grazia, G., Vegetti, C., Bersani, I., Bertolini, G., Molla, A., Baldassari, P., Andriani, F., Roz, L., Sozzi, G., Pastorino, U., Mortarini, R. & Anichini, A., Feb 1 2017, In : Cancer Research. 77, 4, p. 851-861 11 p.

Research output: Contribution to journalArticle

Establishment of patient derived xenografts as functional testing of lung cancer aggressiveness

Moro, M., Giulia, B., Roberto, C., Cristina, B., Mattia, B., Alessandra, F., Giorgia, L., Patrizia, G., Carlotta, G., Giuseppe, P., Luca, R., Gabriella, S. & Ugo, P., Dec 1 2017, In : Scientific Reports. 7, 1, 6689.

Research output: Contribution to journalArticle

FNA and CNB in the diagnosis of pulmonary lesions: A single-center experience on 665 patients, comparison between two periods

Marchianò, A. V., Cosentino, M., Di Tolla, G., Greco, F. G., Silva, M., Sverzellati, N., Fabbri, A., Tamborini, E., Lo Russo, G., Mariani, L., Lalli, L. & Pastorino, U., Jul 1 2017, In : Tumori. 103, 4, p. 360-366 7 p.

Research output: Contribution to journalArticle

Lung cancer screening with low-dose CT in Europe: strength and weakness of diverse independent screening trials

Silva, M., Pastorino, U. & Sverzellati, N., May 1 2017, In : Clinical Radiology. 72, 5, p. 389-400 12 p.

Research output: Contribution to journalArticle

Lung metastasectomy in adenoid cystic cancer: Is it worth it?

Girelli, L., Locati, L., Galeone, C., Scanagatta, P., Duranti, L., Licitra, L. & Pastorino, U., Feb 1 2017, In : Oral Oncology. 65, p. 114-118 5 p.

Research output: Contribution to journalArticle

Mechanical behavior of a total chest wall prosthesis with rib-like features

Girotti, A., Rosa, F., Ferrotto, M., Girotti, P. & Pastorino, U., Nov 18 2017, In : Computer Methods in Biomechanics and Biomedical Engineering. 20, 15, p. 1581-1588 8 p.

Research output: Contribution to journalArticle

Metabolic Evaluation of Non-Small Cell Lung Cancer Patient-Derived Xenograft Models Using 18F-FDG PET: A Potential Tool for Early Therapy Response.

Valtorta, S., Moro, M., Prisinzano, G., Bertolini, G., Tortoreto, M., Raccagni, I., Pastorino, U., Roz, L., Sozzi, G. & Moresco, R. M., Jan 1 2017, In : Journal of Nuclear Medicine. 58, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

MicroRNA based liquid biopsy: The experience of the plasma miRNA signature classifier (MSC) for lung cancer screening

Mensah, M., Borzi, C., Verri, C., Suatoni, P., Conte, D., Pastorino, U., Orazio, F., Sozzi, G. & Boeri, M., Oct 26 2017, In : Journal of Visualized Experiments. 2017, 128, e56326.

Research output: Contribution to journalArticle

Mutational Profile from Targeted NGS Predicts Survival in LDCT Screening–Detected Lung Cancers

Verri, C., Borzi, C., Holscher, T., Dugo, M., Devecchi, A., Drake, K., Sestini, S., Suatoni, P., Romeo, E., Sozzi, G., Pastorino, U. & Boeri, M., Jun 1 2017, In : Journal of Thoracic Oncology. 12, 6, p. 922-931 10 p.

Research output: Contribution to journalArticle

Permeable Nonabsorbable Mesh for Total Diaphragmatic Replacement in Extended Pneumonectomy

Rolli, L., Leuzzi, G., Girotti, P., Duranti, L. & Pastorino, U., Jul 1 2017, In : Annals of Thoracic Surgery. 104, 1, p. e105-e107

Research output: Contribution to journalArticle

Pharmacogenetic study of seven polymorphisms in three nicotinic acetylcholine receptor subunits in smoking-cessation therapies

Pintarelli, G., Galvan, A., Pozzi, P., Noci, S., Pasetti, G., Sala, F., Pastorino, U., Boffi, R. & Colombo, F., 2017, In : Scientific Reports. 7, 1

Research output: Contribution to journalArticle

Pleural plaques in lung cancer screening by low-dose computed tomography: Prevalence, association with lung cancer and mortality

Silva, M., Sverzellati, N., Colombi, D., Milanese, G., La Vecchia, C., Galeone, C., Marchianò, A. & Pastorino, U., Nov 25 2017, In : BMC Pulmonary Medicine. 17, 1, 155.

Research output: Contribution to journalArticle

Primary metastatic osteosarcoma: results of a prospective study in children given chemotherapy and interleukin-2

Meazza, C., Cefalo, G., Massimino, M., Daolio, P., Pastorino, U., Scanagatta, P., Morosi, C., Podda, M., Ferrari, A., Terenziani, M., Spreafico, F., Casanova, M., Parafioriti, A., Collini, P., Gandola, L., Bastoni, S., Biassoni, V., Schiavello, E., Chiaravalli, S., Puma, N. & 2 others, Bergamaschi, L. & Luksch, R., Dec 1 2017, In : Medical Oncology. 34, 12, 191.

Research output: Contribution to journalArticle