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Fingerprint Dive into the research topics where Valentina Cecatiello is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Histone Demethylases Medicine & Life Sciences
Pyrroles Medicine & Life Sciences
Microtubules Medicine & Life Sciences
Lysine Medicine & Life Sciences
Histone Code Medicine & Life Sciences
Histones Medicine & Life Sciences
Inhibitory Concentration 50 Medicine & Life Sciences
Euchromatin Medicine & Life Sciences

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Research Output 2012 2019

Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions

Pirovano, L., Culurgioni, S., Carminati, M., Alfieri, A., Monzani, S., Cecatiello, V., Gaddoni, C., Rizzelli, F., Foadi, J., Pasqualato, S. & Mapelli, M., Dec 1 2019, In : Nature Communications. 10, 1, 2208.

Research output: Contribution to journalArticle

Open Access
Dyneins
Microtubules
division
generators
spindles

A Numb-Mdm2 fuzzy complex reveals an isoformspecific involvement of Numb in breast cancer

Colaluca, I. N., Basile, A., Freiburger, L., D'Uva, V., Disalvatore, D., Vecchi, M., Confalonieri, S., Tosoni, D., Cecatiello, V., Malabarba, M. G., Yang, C. J., Kainosho, M., Sattler, M., Mapelli, M., Pece, S. & di Fiore, P. P., Feb 1 2018, In : Journal of Cell Biology. 217, 2, p. 745-762 18 p.

Research output: Contribution to journalArticle

Exons
Breast Neoplasms
Protein Isoforms
Ubiquitin-Protein Ligases
Homeostasis

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration

Sartori, L., Mercurio, C., Amigoni, F., Cappa, A., Fagá, G., Fattori, R., Legnaghi, E., Ciossani, G., Mattevi, A., Meroni, G., Moretti, L., Cecatiello, V., Pasqualato, S., Romussi, A., Thaler, F., Trifiró, P., Villa, M., Vultaggio, S., Botrugno, O. A., Dessanti, P. & 6 others, Minucci, S., Zagarrí, E., Carettoni, D., Iuzzolino, L., Varasi, M. & Vianello, P., Mar 9 2017, In : Journal of Medicinal Chemistry. 60, 5, p. 1673-1692 20 p.

Research output: Contribution to journalArticle

Histone Demethylases
Pyrroles
Inhibitory Concentration 50
Lysine
Enzymes

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship

Vianello, P., Sartori, L., Amigoni, F., Cappa, A., Fagá, G., Fattori, R., Legnaghi, E., Ciossani, G., Mattevi, A., Meroni, G., Moretti, L., Cecatiello, V., Pasqualato, S., Romussi, A., Thaler, F., Trifiró, P., Villa, M., Botrugno, O. A., Dessanti, P., Minucci, S. & 4 others, Vultaggio, S., Zagarrí, E., Varasi, M. & Mercurio, C., Mar 9 2017, In : Journal of Medicinal Chemistry. 60, 5, p. 1693-1715 23 p.

Research output: Contribution to journalArticle

Histone Demethylases
Pyrroles
Drug Design
Structure-Activity Relationship
Inhibitory Concentration 50
Microfilament Proteins
Crystallization
X-Ray Diffraction
crystallization
proteins