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Research Output 1987 2019

2019

Number and brightness analysis reveals that NCAM and FGF2 elicit different assembly and dynamics of FGFR1 in live cells

Zamai, M., Trullo, A., Giordano, M., Corti, V., Cuesta, E. A., Francavilla, C., Cavallaro, U. & Caiolfa, V. R., Jan 1 2019, In : Journal of Cell Science. 132, 1, jcs220624.

Research output: Contribution to journalArticle

Open Access
Fibroblast Growth Factor 1
Neural Cell Adhesion Molecules
Fibroblast Growth Factor Receptors
Fibroblast Growth Factor 2
Ligands
Oligomerization
Fluorophores
Fluorescence microscopy
Cell Surface Receptors
Fluorescence Microscopy
2018

MouBeAT: A new and open toolbox for guided analysis of behavioral tests in mice

Bello-Arroyo, E., Roque, H., Marcos, A., Orihuel, J., Higuera-Matas, A., Desco, M., Caiolfa, VR., Ambrosio, E., Lara-Pezzi, E. & Gómez-Gaviro, MV., 2018, In : Frontiers in Behavioral Neuroscience. 12, 201.

Research output: Contribution to journalArticle

Nervous System Diseases
Rodentia
Theoretical Models
Software
Psychology
2017

Efficient up-conversion in Yb:Er:NaT(XO4)2 thermal nanoprobes. Imaging of their distribution in a perfused mouse

Zaldo, C., Serrano, MD., Han, X., Cascales, C., Cantero, M., Montoliu, L., Arza, E., Caiolfa, VR. & Zamai, M., 2017, In : PLoS One. 12, 5, e0177596.

Research output: Contribution to journalArticle

Phonons
Nanoprobes
nanoparticles
Nanoparticles
Oxides
2016

Human in vitro 3D co-culture model to engineer vascularized bone-mimicking tissues combining computational tools and statistical experimental approach

Bersini, S., Gilardi, M., Arrigoni, C., Talò, G., Zamai, M., Zagra, L., Caiolfa, V. & Moretti, M. G., 2016, In : Biomaterials. 76, p. 157-172 16 p.

Research output: Contribution to journalArticle

Coculture Techniques
Bone
Tissue
Engineers
Bone and Bones

Human in vitro 3D co-culture model to engineer vascularized bone-mimicking tissues combining computational tools and statistical experimental approach

Bersini, S., Gilardi, M., Arrigoni, C., Talò, G., Zamai, M., Zagra, L., Caiolfa, V. & Moretti, M., 2016, In : Biomaterials. 76, p. 157-172 16 p.

Research output: Contribution to journalArticle

Coculture Techniques
Bone
Tissue
Engineers
Bone and Bones
2013

Application limits and data correction in number of molecules and brightness analysis

Trullo, A., Corti, V., Arza, E., Caiolfa, V. R. & Zamai, M., Nov 2013, In : Microscopy Research and Technique. 76, 11, p. 1135-1146 12 p.

Research output: Contribution to journalArticle

Luminance
brightness
Photobleaching
Molecules
Lighting

CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses

Rocha-Perugini, V., Zamai, M., González-Granado, J. M., Barreiro, O., Tejera, E., Yañez-Mó, M., Caiolfa, V. R. & Sanchez-Madrid, F., 2013, In : Molecular and Cellular Biology. 33, 18, p. 3644-3658 15 p.

Research output: Contribution to journalArticle

Immunological Synapses
Synapses
T-Lymphocytes
Intercellular Adhesion Molecule-1
Viral Tumor Antigens
2011

Number and brightness image analysis reveals ATF-induced dimerization kinetics of uPAR in the cell membrane

Hellriegel, C., Caiolfa, V. R., Corti, V., Sidenius, N. & Zamai, M., Sep 2011, In : FASEB Journal. 25, 9, p. 2883-2897 15 p.

Research output: Contribution to journalArticle

Dimerization
Cell membranes
Image analysis
Luminance
Cell Membrane
2010

HS1 has a central role in the trafficking and homing of leukemic B cells

Scielzo, C., Bertilaccio, M. T. S., Simonetti, G., Dagklis, A., Ten Hacken, E., Fazi, C., Muzio, M., Caiolfa, V., Kitamura, D., Restuccia, U., Bachi, A., Rocchi, M., Ponzoni, M., Ghia, P. & Caligaris-Cappio, F., Nov 4 2010, In : Blood. 116, 18, p. 3537-3546 10 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Lymphocytes
B-Lymphocytes
Cells
Infiltration
2008

Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms

Barreiro, O., Zamai, M., Yáñez-Mó, M., Tejera, E., López-Romero, P., Monk, P. N., Gratton, E., Caiolfa, V. R. & Sánchez-Madrid, F., Nov 3 2008, In : Journal of Cell Biology. 183, 3, p. 527-542 16 p.

Research output: Contribution to journalArticle

Adhesives
Vascular Cell Adhesion Molecule-1
Leukocytes
Intercellular Adhesion Molecule-1
Integrins
Urokinase Plasminogen Activator Receptors
Glycosylphosphatidylinositols
Fluorescence Spectrometry
Photons
histograms

Measuring uPAR dynamics in live cells

Zamai, M., Malengo, G. & Caiolfa, V. R., 2008, The Cancer Degradome: Proteases and Cancer Biology. Springer New York, p. 475-493 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Urokinase Plasminogen Activator Receptors
Plasminogen
Urokinase-Type Plasminogen Activator
Membrane Proteins
Chemical activation

The phasor approach to fluorescence lifetime imaging analysis

Digman, M. A., Caiolfa, V. R., Zamai, M. & Gratton, E., Jan 15 2008, In : Biophysical Journal. 94, 2

Research output: Contribution to journalArticle

Optical Imaging
Microscopy
Fluorescence
Fluorescence Resonance Energy Transfer
Cluster Analysis
2007

Monomer-dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies

Caiolfa, V. R., Zamai, M., Malengo, G., Andolfo, A., Madsen, C. D., Sutin, J., Digman, M. A., Gratton, E., Blasi, F. & Sidenius, N., Dec 3 2007, In : Journal of Cell Biology. 179, 5, p. 1067-1082 16 p.

Research output: Contribution to journalArticle

Glycosylphosphatidylinositols
Membrane Proteins
Cell Membrane
Urokinase Plasminogen Activator Receptors
Vitronectin
2006

Interaction between basic fibroblast growth factor and the anti-angiogenic drug PNU145156E

Zamai, M., Hariharan, C., Pines, D., Safran, M., Yayon, A., Caiolfa, V. R., Mariani, M., Pines, E., Cohen-Luria, R. & Parola, A. H., Jul 3 2006, In : Journal of Molecular Structure. 792-793, p. 23-35 13 p.

Research output: Contribution to journalArticle

Angiogenesis Inhibitors
fibroblasts
Fibroblast Growth Factor 2
Fibroblasts
Heparin
2005

GR and HMGB1 interact only within chromatin and influence each other's residence time

Agresti, A., Scaffidi, P., Riva, A., Caiolfa, V. R. & Bianchi, M. E., Apr 1 2005, In : Molecular Cell. 18, 1, p. 109-121 13 p.

Research output: Contribution to journalArticle

HMGB1 Protein
Chromatin
Glucocorticoid Receptors
Nuclear Proteins
Transcription Factors
2004

Aggregation properties of a HPMA-camptothecin copolymer in isotonic solutions

Chirico, G., Collini, M., Olivini, F., Zamai, M., Frigerio, E. & Caiolfa, V. R., Aug 1 2004, In : Biophysical Chemistry. 110, 3, p. 281-295 15 p.

Research output: Contribution to journalArticle

Isotonic Solutions
Camptothecin
copolymers
Agglomeration
Copolymers
2003

Camptothecin poly[N-(2-hydroxypropyl) methacrylamide] copolymers in antitopoisomerase-I tumor therapy: Intratumor release and antitumor efficacy

Zamai, M., VandeVen, M., Farao, M., Gratton, E., Ghiglieri, A., Castelli, M. G., Fontana, E., D'Argy, R., Fiorino, A., Pesenti, E., Suarato, A. & Caiolfa, V. R., Jan 2003, In : Molecular Cancer Therapeutics. 2, 1, p. 29-40 12 p.

Research output: Contribution to journalArticle

Camptothecin
Gly-Phe-Leu-Gly
Neoplasms
Therapeutics
Duxon
2002
Pyrroles
Protein Folding
Fibroblast Growth Factor 2
Heparin
Pharmaceutical Preparations
2001

Thermodynamics of the high-affinity interaction of TCF4 with β-catenin

Knapp, S., Zamai, M., Volpi, D., Nardese, V., Avanzi, N., Breton, J., Plyte, S., Flocco, M., Marconi, M., Isacchi, A. & Caiolfa, V. R., Mar 9 2001, In : Journal of Molecular Biology. 306, 5, p. 1179-1189 11 p.

Research output: Contribution to journalArticle

Catenins
Thermodynamics
High Mobility Group Proteins
Calorimetry
Wnt Signaling Pathway
2000

Polymer-bound camptothecin: Initial biodistribution and antitumour activity studies

Caiolfa, V. R., Zamai, M., Fiorino, A., Frigerio, E., Pellizzoni, C., D'Argy, R., Ghiglieri, A., Castelli, M. G., Farao, M., Pesenti, E., Gigli, M., Angelucci, F. & Suarato, A., Mar 1 2000, In : Journal of Controlled Release. 65, 1-2, p. 105-119 15 p.

Research output: Contribution to journalArticle

Camptothecin
Polymers
Poisons
Gly-Phe-Leu-Gly
Intravenous Administration
Dipeptidyl Peptidase 4
Adenosine Deaminase
Phase Transition
Phase transitions
Cholesterol
1999

Determination of the affinity of drugs toward serum albumin by measurement of the quenching of the intrinsic tryptophan fluorescence of the protein

Epps, D. E., Raub, T. J., Caiolfa, V., Chiari, A. & Zamai, M., Jan 1999, In : Journal of Pharmacy and Pharmacology. 51, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

Serum Albumin
Tryptophan
Fluorescence
Pharmaceutical Preparations
Proteins
1998
Pyrroles
Fibroblast Growth Factor 2
Pharmaceutical Preparations
Fluorescence
Binding Sites

Probing the active site of adenosine deaminase by a pH responsive fluorescent competitive inhibitor

Caiolfa, V. R., Gill, D. & Parola, A. H., Jan 1 1998, In : Biophysical Chemistry. 70, 1, p. 41-56 16 p.

Research output: Contribution to journalArticle

adenosines
Adenosine Deaminase
adenines
inhibitors
Catalytic Domain
1997

Antiangiogenic naphthalene sulfonic distamycin-A derivatives tightly interact with human basic fibroblast growth factor

Zamai, M., Parola, A. H., Grandi, M., Mongelli, N. & Caiolfa, V. R., 1997, In : Medicinal Chemistry Research. 7, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

Affinity chromatography
Fluorescence Polarization
Fibroblast Growth Factor 2
Affinity Chromatography
Intercellular Signaling Peptides and Proteins
1995

Fluorescence polarization assay for endothelin-converting enzymes

Hazan, S., Fishov, I., Zamai, M., Caiolfa, V. R. & Parola, A. H., 1995, In : Peptides. 16, 5, p. 833-836 4 p.

Research output: Contribution to journalArticle

Fluorescence Polarization
Endothelins
Chymotrypsin
Endothelin-1
Assays
1993

In vivo expression of mutant preproendothelins: Hierarchy of processing events but no strict requirement of Trp-Val at the processing site

Fabbrini, M. S., Vitale, A., Pedrazzini, E., Nitti, G., Zamai, M., Tamburin, M., Caiolfa, V. R., Patrono, C. & Benatti, L., May 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 9, p. 3923-3927 5 p.

Research output: Contribution to journalArticle

Endothelin-1
Oocytes
Amino Acids
Terminator Codon
Vasoconstrictor Agents
Endothelins
Endothelin-1
Peptides
Substrates
Chymotrypsin
1992

Human preproendothelin-1 is converted into active endothelin-1 by baculovirus-infected insect cells

Benatti, L., Cozzi, L., Zamai, M., Tamburin, M., Vaghi, F., Caiolfa, V. R., Fabbrini, M. S. & Sarmientos, P., Jul 31 1992, In : Biochemical and Biophysical Research Communications. 186, 2, p. 753-759 7 p.

Research output: Contribution to journalArticle

Sf9 Cells
Baculoviridae
Endothelin-1
Insects
Venae Cavae
1991

Big endothelin-converting enzyme activities in subcellular fractions of bovine aortic endothelial cells

Galvani, A. P., Zamai, M., Nitti, G. P., Curatolo, L., Ciavolella, A. & Caiolfa, V. R., 1991, In : Journal of Cardiovascular Pharmacology. 17, p. S47-S51

Research output: Contribution to journalArticle

Subcellular Fractions
Endothelin-1
Endothelial Cells
Tosylphenylalanyl Chloromethyl Ketone
Chymases

Heterologous in vivo processing of human preproendothelin 1 into bioactive peptides

Fabbrini, M. S., Vitale, A., Patrono, C., Zamai, M., Vaghi, F., Caiolfa, V., Monaco, L. & Benatti, L., Oct 15 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 20, p. 8939-8943 5 p.

Research output: Contribution to journalArticle

Endothelin-1
Oocytes
Peptides
Endothelins
Vasoconstrictor Agents
1990

Membrane lipid-protein interactions modify the regulatory role of adenosine-deaminase complexing protein. A phase fluorometry study of a malignancy marker

Parola, A. H., Porat, N., Caiolfa, V. R., Gill, D., Kiesow, L. A., Weisman, M., Nemschitz, S., Yaron, D., Singer, K. & Solomon, E., 1990, Proceedings of SPIE - The International Society for Optical Engineering. Lakowicz, J. F. (ed.). Publ by Int Soc for Optical Engineering, Vol. 1204 pt 2. p. 830-842 13 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

adenosines
markers
lipids
Liposomes
Cholesterol

The protonated form of 1-N6-etheno-[erythro-9-(2-hydroxy-3-nonyl)] adenine is identified at the active site of adenosine deaminase

Caiolfa, V. R., Gill, D. & Parola, A. H., Jan 15 1990, In : FEBS Letters. 260, 1, p. 19-22 4 p.

Research output: Contribution to journalArticle

Adenosine Deaminase
Catalytic Domain
Adenosine Deaminase Inhibitors
Protonation
Adenine
1989

Laser photobleaching leads to a fluorescence grade adenosine deaminase

Parola, A. H., Caiolfa, V. R., Bar, I. & Rosenwaks, S., 1989, In : Analytical Biochemistry. 181, 2, p. 383-388 6 p.

Research output: Contribution to journalArticle

Photobleaching
Adenosine Deaminase
Lasers
Fluorescence
adenosine nucleosidase
1988

Adenosine deaminase-complexing protein from bovine kidney. Isolation of two distinct subunits

Weisman, M. I., Caiolfa, V. R. & Parola, A. H., 1988, In : Journal of Biological Chemistry. 263, 11, p. 5266-5270 5 p.

Research output: Contribution to journalArticle

Adenosine Deaminase
Kidney
Proteins
Adenosine
Sepharose
1987

Quantitative structure-activity analysis in dihydropteroate synthase inhibition by sulfones. Comparison with sulfanilamides

De Benedetti, P. G., Iarossi, D., Menziani, C., Caiolfa, V., Frassineti, C. & Cennamo, C., 1987, In : Journal of Medicinal Chemistry. 30, 3, p. 459-464 6 p.

Research output: Contribution to journalArticle

Sulfanilamides
Dihydropteroate Synthase
Sulfones
Electronic structure
para-Aminobenzoates