• 7938 Citations
  • 43 h-Index
1993 …2019
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Fingerprint Dive into the research topics where Vania Broccoli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles
Genes Medicine & Life Sciences
Neurons Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Brain Medicine & Life Sciences
Neural Stem Cells Medicine & Life Sciences
Homeobox Genes Medicine & Life Sciences
Fibroblasts Medicine & Life Sciences
Mutation Medicine & Life Sciences

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Research Output 1993 2019

  • 7938 Citations
  • 43 h-Index
  • 109 Article

dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice

Colasante, G., Lignani, G., Brusco, S., Di Berardino, C., Carpenter, J., Giannelli, S., Valassina, N., Bido, S., Ricci, R., Castoldi, V., Marenna, S., Church, T., Massimino, L., Morabito, G., Benfenati, F., Schorge, S., Leocani, L., Kullmann, D. M. & Broccoli, V., Jan 1 2019, (Accepted/In press) In : Molecular Therapy.

Research output: Contribution to journalArticle

Myoclonic Epilepsy
Interneurons
Transcriptional Activation
Seizures
Haploinsufficiency
Retinitis Pigmentosa
Rhodopsin
Clustered Regularly Interspaced Short Palindromic Repeats
Alleles
Genes

Folic Acid Exposure Rescues Spina Bifida Aperta Phenotypes in Human Induced Pluripotent Stem Cell Model

Sahakyan, V., Duelen, R., Tam, WL., Roberts, SJ., Grosemans, H., Berckmans, P., Ceccarelli, G., Pelizzo, G., Broccoli, V., Deprest, J., Luyten, FP., Verfaillie, CM. & Sampaolesi, M., 2018, In : Scientific Reports. 8, 5, 2942.

Research output: Contribution to journalArticle

Spina Bifida Cystica
Induced Pluripotent Stem Cells
Neural Tube Defects
Folic Acid
Phenotype

Gene therapy approaches in the non-human primate model of Parkinson’s disease

Pignataro, D., Sucunza, D., Rico, AJ., Dopeso-Reyes, IG., Roda, E., Rodríguez-Perez, AI., Labandeira-Garcia, JL., Broccoli, V., Kato, S., Kobayashi, K. & Lanciego, JL., 2018, In : Journal of Neural Transmission. 125, 3, p. 575-589 15 p.

Research output: Contribution to journalArticle

Genetic Therapy
Primates
Parkinson Disease
alpha-Synuclein
Basal Ganglia

KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes

Barbagiovanni, G., Germain, PL., Zech, M., Atashpaz, S., Lo Riso, P., D'Antonio-Chronowska, A., Tenderini, E., Caiazzo, M., Boesch, S., Jech, R., Haslinger, B., Broccoli, V., Stewart, AF., Winkelmann, J. & Testa, G., 2018, In : Cell Reports. 25, 4, p. 988-1001 14 p.

Research output: Contribution to journalArticle

Dystonia
Fibroblasts
Genes
Histones
Lysine