20032019

Research output per year

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Research Output

2019

Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation

Mongiardi, M. P., Radice, G., Piras, M., Stagni, V., Pacioni, S., Re, A., Putti, S., Ferrè, F., Farsetti, A., Pallini, R., Barilà, D., Levi, A. & Falchetti, M. L., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

2018

Caspase-8: A novel target to overcome resistance to chemotherapy in glioblastoma

Fianco, G., Contadini, C., Ferri, A., Cirotti, C., Stagni, V. & Barilà, D., Dec 1 2018, In : International Journal of Molecular Sciences. 19, 12, 3798.

Research output: Contribution to journalReview article

2017

ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

Antonelli, M., Strappazzon, F., Arisi, I., Brandi, R., D'Onofrio, M., Sambucci, M., Manic, G., Vitale, I., Barilà, D. & Stagni, V., Jan 1 2017, In : Oncotarget. 8, 13, p. 21692-21709 18 p.

Research output: Contribution to journalArticle

2016

ATM: An unexpected tumor-promoting factor in HER2-expressing tumors

Stagni, V., Oropallo, V. & Barilà, D., Mar 2016, In : Molecular & cellular oncology. 3, 2, p. e1054551

Research output: Contribution to journalArticle

2015

ATM kinase sustains HER2 tumorigenicity in breast cancer

Stagni, V., Manni, I., Oropallo, V., Mottolese, M., Di Benedetto, A., Piaggio, G., Falcioni, R., Giaccari, D., Di Carlo, S., Sperati, F., Cencioni, M. T. & Barilà, D., Apr 16 2015, In : Nature Communications. 6, 6886.

Research output: Contribution to journalArticle

2014

ATM kinase activity modulates ITCH E3-ubiquitin ligase activity

Santini, S., Stagni, V., Giambruno, R., Fianco, G., Di Benedetto, A., Mottolese, M., Pellegrini, M. & Barilà, D., Feb 27 2014, In : Oncogene. 33, 9, p. 1113-1123 11 p.

Research output: Contribution to journalArticle

ITCH E3 ligase in ATM network

Stagni, V., Santini, S. & Barilà, D., 2014, In : Oncoscience. 1, 6, p. 394-395 2 p.

Research output: Contribution to journalArticle

Tug of war between survival and death: Exploring ATM function in cancer

Stagni, V., Oropallo, V., Fianco, G., Antonelli, M., Cinà, I. & Barilà, D., Mar 27 2014, In : International Journal of Molecular Sciences. 15, 4, p. 5388-5409 22 p.

Research output: Contribution to journalArticle

2013

ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition

Gilardini Montani, M. S., Prodosmo, A., Stagni, V., Merli, D., Monteonofrio, L., Gatti, V., Gentileschi, M. P., Barilà, D. & Soddu, S., Nov 19 2013, In : Journal of Experimental and Clinical Cancer Research. 32, 1, 95.

Research output: Contribution to journalArticle

2012

A new player in the development of TRAIL based therapies for hepatocarcinoma treatment: ATM kinase

Stagni, V., Santini, S. & Barilà, D., Jun 2012, In : Cancers. 4, 2, p. 354-378 25 p.

Research output: Contribution to journalArticle

Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver

Furlan, A., Lamballe, F., Stagni, V., Hussain, A., Richelme, S., Prodosmo, A., Moumen, A., Brun, C., Del Barco Barrantes, I., Arthur, J. S. C., Koleske, A. J., Nebreda, A. R., Barilà, D. & Maina, F., Dec 2012, In : Journal of Hepatology. 57, 6, p. 1292-1298 7 p.

Research output: Contribution to journalArticle

Proteomic profiling of ATM kinase proficient and deficient cell lines upon blockage of proteasome activity

Marzano, V., Santini, S., Rossi, C., Zucchelli, M., D'Alessandro, A., Marchetti, C., Mingardi, M., Stagni, V., Barilà, D. & Urbani, A., Aug 3 2012, In : Journal of Proteomics. 75, 15, p. 4632-4646 15 p.

Research output: Contribution to journalArticle

2011

Abl interconnects oncogenic Met and p53 core pathways in cancer cells

Furlan, A., Stagni, V., Hussain, A., Richelme, S., Conti, F., Prodosmo, A., Destro, A., Roncalli, M., Barilà, D. & Mainá, F., Oct 2011, In : Cell Death and Differentiation. 18, 10, p. 1608-1616 9 p.

Research output: Contribution to journalArticle

Oxygen sensing is impaired in ATM defective cells

Mongiardi, M. P., Stagni, V., Natoli, M., Giaccari, D., D'Agnano, I., Falchetti, M. L., Barilà, D. & Levi, A., Dec 15 2011, In : Cell Cycle. 10, 24, p. 4311-4320 10 p.

Research output: Contribution to journalArticle

2010

ATM kinase activity modulates cFLIP protein levels: Potential interplay between DNA damage signalling and TRAIL-induced apoptosis

Stagni, V., Mingardi, M., Santini, S., Giaccari, D. & Barilà, D., Nov 2010, In : Carcinogenesis. 31, 11, p. 1956-1963 8 p.

Research output: Contribution to journalArticle

2008

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells

Stagni, V., Di Bari, M. G., Cursi, S., Condò, I., Cencioni, M. T., Testi, R., Lerenthal, Y., Cundari, E. & Barilà, D., Jan 15 2008, In : Blood. 111, 2, p. 829-837 9 p.

Research output: Contribution to journalArticle

Identification of a critical tyrosine residue in caspase 8 that promotes cell migration

Barbero, S., Barilà, D., Mielgo, A., Stagni, V., Clair, K. & Stupack, D., May 9 2008, In : Journal of Biological Chemistry. 283, 19, p. 13031-13034 4 p.

Research output: Contribution to journalArticle

2006

Src kinase phosphorylates Caspase-8 on Tyr380: A novel mechanism of apoptosis suppression

Cursi, S., Rufini, A., Stagni, V., Condò, I., Matafora, V., Bachi, A., Bonifazi, A. P., Coppola, L., Superti-Furga, G., Testi, R. & Barilà, D., May 3 2006, In : EMBO Journal. 25, 9, p. 1895-1905 11 p.

Research output: Contribution to journalArticle

2003

Erratum: p120 catenin is required for growth factor-dependent cell motility and scattering in epithelial cells (Molecular Biology of the Cell (2003) 14 (1964-1977))

Cozzolino, M., Stagni, V., Spinardi, L., Campioni, N., Fiorentini, C., Salvati, E., Alema, S. & Salvatore, A. M., Jun 1 2003, In : Molecular Biology of the Cell. 14, 6

Research output: Contribution to journalArticle

P120 catenin is required for growth factor-dependent cell motility and scattering in epithelial cells

Cozzolino, M., Stagni, V., Spinardi, L., Campioni, N., Fiorentini, C., Salvati, E., Alemà, S. & Salvatore, A. M., May 1 2003, In : Molecular Biology of the Cell. 14, 5, p. 1964-1977 14 p.

Research output: Contribution to journalArticle