If you made any changes in Pure these will be visible here soon.

Research Output 2005 2017

Filter
Article
2017
Fibrosis
B-Lymphocytes
Hepatocellular Carcinoma
Liver
Wounds and Injuries
2015

IL-10 critically modulates B cell responsiveness in rankl-/- mice

Marrella, V., Lo Iacono, N., Fontana, E., Sobacchi, C., Sic, H., Schena, F., Sereni, L., Castiello, M. C., Poliani, P. L., Vezzoni, P., Cassani, B., Traggiai, E. & Villa, A., May 1 2015, In : Journal of Immunology. 194, 9, p. 4144-4153 10 p.

Research output: Contribution to journalArticle

RANK Ligand
Interleukin-10
B-Lymphocytes
Regulatory B-Lymphocytes
Plasma Cells
2014

Corrigendum: Rag defects and thymic stroma: Lessons from animal models

Marrella, V., Poliani, P. L., Notarangelo, L. D., Grassi, F. & Villa, A., 2014, In : Frontiers in Immunology. 5, AUG, Article 407.

Research output: Contribution to journalArticle

Rag defects and thymic stroma: Lessons from animal models

Marrella, V., Poliani, P. L., Notarangelo, L. D. & Villa, A., 2014, In : Frontiers in Immunology. 5, JUN, 259.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Animal Models
T-Lymphocytes
Epithelial Cells
Thymocytes
2013

Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration

Maina, V., Marrella, V., Mantero, S., Cassani, B., Fontana, E., Anselmo, A., Del Prete, A., Sozzani, S., Vezzoni, P., Poliani, P. L. & Villa, A., Dec 2013, In : Journal of Leukocyte Biology. 94, 6, p. 1221-1230 10 p.

Research output: Contribution to journalArticle

Dendritic Cells
Cell Movement
Skin
Mutation
Genes
2012

Anti-CD3ε mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: Therapeutic implications

Marrella, V., Poliani, P. L., Fontana, E., Casati, A., Maina, V., Cassani, B., Ficara, F., Cominelli, M., Schena, F., Paulis, M., Traggiai, E., Vezzoni, P., Grassi, F. & Villa, A., Aug 2 2012, In : Blood. 120, 5, p. 1005-1014 10 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Monoclonal Antibodies
T-cells
Autoimmunity
Animals

Osteopetrosis rescue upon RANKL administration to Rankl-/- mice: A new therapy for human RANKL-dependent ARO

Lo Iacono, N., Blair, H. C., Poliani, P. L., Marrella, V., Ficara, F., Cassani, B., Facchetti, F., Fontana, E., Guerrini, M. M., Traggiai, E., Schena, F., Paulis, M., Mantero, S., Inforzato, A., Valaperta, S., Pangrazio, A., Crisafulli, L., Maina, V., Kostenuik, P., Vezzoni, P. & 2 others, Villa, A. & Sobacchi, C., Dec 2012, In : Journal of Bone and Mineral Research. 27, 12, p. 2501-2510 10 p.

Research output: Contribution to journalArticle

Osteopetrosis
Inborn Genetic Diseases
Hematopoietic Stem Cell Transplantation
Thymus Gland
Therapeutics

RANK-dependent autosomal recessive osteopetrosis: Characterization of five new cases with novel mutations

Pangrazio, A., Cassani, B., Guerrini, M. M., Crockett, J. C., Marrella, V., Zammataro, L., Strina, D., Schulz, A., Schlack, C., Kornak, U., Mellis, D. J., Duthie, A., Helfrich, M. H., Durandy, A., Moshous, D., Vellodi, A., Chiesa, R., Veys, P., Lo Iacono, N., Vezzoni, P. & 3 others, Fischer, A., Villa, A. & Sobacchi, C., 2012, In : Journal of Bone and Mineral Research. 27, 2, p. 342-351 10 p.

Research output: Contribution to journalArticle

Osteopetrosis
Osteoclasts
Mutation
Immune System
Receptor Activator of Nuclear Factor-kappa B
2011

Omenn syndrome does not live by V(D)J recombination alone

Marrella, V., Maina, V. & Villa, A., Dec 2011, In : Current Opinion in Allergy and Clinical Immunology. 11, 6, p. 525-531 7 p.

Research output: Contribution to journalArticle

V(D)J Recombination
Severe Combined Immunodeficiency
Genes
Exfoliative Dermatitis
Genetic Recombination
2010

Defect of regulatory T cells in patients with Omenn syndrome

Cassani, B., Poliani, P. L., Moratto, D., Sobacchi, C., Marrella, V., Imperatori, L., Vairo, D., Plebani, A., Giliani, S., Vezzoni, P., Facchetti, F., Porta, F., Notarangelo, L. D., Villa, A. & Badolato, R., Jan 2010, In : Journal of Allergy and Clinical Immunology. 125, 1-3, p. 209-216 8 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Regulatory T-Lymphocytes
T-Lymphocytes
Peripheral Tolerance
Genetic Recombination

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome

Cassani, B., Poliani, P. L., Marrella, V., Schena, F., Sauer, A. V., Ravanini, M., Strina, D., Busse, C. E., Regenass, S., Wardemann, H., Martini, A., Facchetti, F., Van Der Burg, M., Rolink, A. G., Vezzoni, P., Grassi, F., Traggiai, E. & Villa, A., Jul 5 2010, In : Journal of Experimental Medicine. 207, 7, p. 1525-1540 16 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Antibody-Producing Cells
B-Lymphocytes
Autoantibodies
B-Cell Activating Factor

Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells

Poliani, P. L., Kisand, K., Marrella, V., Ravanini, M., Notarangelo, L. D., Villa, A., Peterson, P. & Facchetti, F., Mar 2010, In : American Journal of Pathology. 176, 3, p. 1104-1112 9 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
Dendritic Cells
Lymph Nodes
Antigens
Indoleamine-Pyrrole 2,3,-Dioxygenase
2008

Genetically determined lymphopenia and autoimmune manifestations

Villa, A., Marrella, V., Rucci, F. & Notarangelo, L. D., Jun 2008, In : Current Opinion in Immunology. 20, 3, p. 318-324 7 p.

Research output: Contribution to journalArticle

Lymphopenia
T-Lymphocytes
V(D)J Recombination
B-Lymphocytes
Lymphocytes

Of Omenn and mice

Marrella, V., Poliani, P. L., Sobacchi, C., Grassi, F. & Villa, A., Mar 2008, In : Trends in Immunology. 29, 3, p. 133-140 8 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Lymphopenia
Autoimmunity
T-Lymphocytes
B-Lymphocytes
2007

A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome

Marrella, V., Poliani, P. L., Casati, A., Rucci, F., Frascoli, L., Gougeon, M. L., Lemercier, B., Bosticardo, M., Ravanini, M., Battaglia, M., Roncarolo, M. G., Cavazzana-Calvo, M., Facchetti, F., Notarangelo, L. D., Vezzoni, P., Grassi, F. & Villa, A., May 1 2007, In : Journal of Clinical Investigation. 117, 5, p. 1260-1269 10 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
T-Lymphocytes
B-Lymphocytes
V(D)J Recombination
Immune Tolerance
2006

RAG-dependent primary immunodeficiencies

Sobacchi, C., Marrella, V., Rucci, F., Vezzoni, P. & Villa, A., Dec 2006, In : Human Mutation. 27, 12, p. 1174-1184 11 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
RAG-1 Genes
B-Lymphocytes
Genotype
T-Lymphocytes

Tissue-specific sensitivity to AID expression in transgenic mouse models

Rucci, F., Cattaneo, L., Marrella, V., Sacco, M. G., Sobacchi, C., Lucchini, F., Nicola, S., Della Bella, S., Villa, M. L., Imberti, L., Gentili, F., Montagna, C., Tiveron, C., Tatangelo, L., Facchetti, F., Vezzoni, P. & Villa, A., Aug 1 2006, In : Gene. 377, 1-2, p. 150-158 9 p.

Research output: Contribution to journalArticle

Transgenic Mice
Human T-lymphotropic virus 1
Thymocytes
Lymphoma
B-Lymphocytes
2005

AIRE deficiency in thymus of 2 patients with Omenn syndrome

Cavadini, P., Vermi, W., Facchetti, F., Fontana, S., Nagafuchi, S., Mazzolari, E., Sediva, A., Marrella, V., Villa, A., Fischer, A., Notarangelo, L. D. & Badolato, R., Mar 2005, In : Journal of Clinical Investigation. 115, 3, p. 728-732 5 p.

Research output: Contribution to journalArticle

Autoimmune Polyendocrinopathies
Severe Combined Immunodeficiency
Thymus Gland
T-Lymphocytes
Messenger RNA

C1-inhibitor protects against brain ischemia-reperfusion injury via inhibition of cell recruitment and inflammation

Storini, C., Rossi, E., Marrella, V., Distaso, M., Veerhuis, R., Vergani, C., Bergamaschini, L. & De Simoni, M. G., Jun 2005, In : Neurobiology of Disease. 19, 1-2, p. 10-17 8 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Brain Ischemia
Cytokines
Inflammation
Kinins

Damaging-agent sensitivity of Artemis-deficient cell lines

Musio, A., Marrella, V., Sobacchi, C., Rucci, F., Fariselli, L., Giliani, S., Lanzi, G., Notarangelo, L. D., Delia, D., Colombo, R., Vezzoni, P. & Villa, A., Apr 2005, In : European Journal of Immunology. 35, 4, p. 1250-1256 7 p.

Research output: Contribution to journalArticle

Genomic Instability
Cell Line
Severe Combined Immunodeficiency
DNA Damage
V(D)J Recombination