• 5201 Citations
  • 37 h-Index
1984 …2019
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Research Output 1984 2019

  • 5201 Citations
  • 37 h-Index
  • 141 Article
  • 1 Chapter
  • 1 Review article
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Article
2019

Automated workflow for somatic and Germline next generation sequencing analysis in routine clinical cancer diagnostics

Muscarella, L. A., Fabrizio, F. P., De Bonis, M., Mancini, M. T., Balsamo, T., Graziano, P., Centra, F., Sparaneo, A., Trombetta, D., Bonfitto, A., Scagliusi, V., Larizza, P., Capoluongo, E. D. & Fazio, V. M., Nov 2019, In : Cancers. 11, 11, 1691.

Research output: Contribution to journalArticle

Open Access
Workflow
Automation
DNA
Neoplasms
Paraffin

Diagnostic and prognostic value of B4GALT1 hypermethylation and its clinical significance as a novel circulating cell-free DNA biomarker in colorectal cancer

Picardo, F., Romanelli, A., Muinelo-Romay, L., Mazza, T., Fusilli, C., Parrella, P., Barbazán, J., Lopez-López, R., Barbano, R., De Robertis, M., Taffon, C., Bordoni, V., Agrati, C., Costantini, M., Ricci, F., Graziano, P., Maiello, E., Muscarella, L. A., Fazio, V. M. & Poeta, M. L., Oct 2019, In : Cancers. 11, 10, p. 1-16 16 p., 1598.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Biomarkers
DNA
Methylation
Neoplasm Metastasis

Diagnostic and prognostic value of B4GALT1 hypermethylation and its clinical significance as a novel circulating cell-free DNA biomarker in colorectal cancer

Picardo, F., Romanelli, A., Muinelo-Romay, L., Mazza, T., Fusilli, C., Parrella, P., Barbazán, J., Lopez-López, R., Barbano, R., De Robertis, M., Taffon, C., Bordoni, V., Agrati, C., Costantini, M., Ricci, F., Graziano, P., Maiello, E., Muscarella, L. A., Fazio, V. M. & Poeta, M. L., 2019, In : Cancers. 11, 10

Research output: Contribution to journalArticle

Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors

Sparaneo, A., Fabrizio, F. P., la Torre, A., Graziano, P., Di Maio, M., Fontana, A., Bisceglia, M., Rossi, A., Pizzolitto, S., De Maglio, G., Tancredi, A., Grimaldi, F., Balsamo, T., Centra, F., Manzorra, M. C., Trombetta, D., Pantalone, A., Bonfitto, A., Maiello, E., Fazio, V. M. & 1 others, Muscarella, L. A., May 23 2019, In : International Journal of Molecular Sciences. 20, 10

Research output: Contribution to journalArticle

Open Access
Neuroendocrine Tumors
Carcinoid Tumor
lungs
Tumors
Methylation

Hsa-miR-210-3p expression in breast cancer and its putative association with worse outcome in patients treated with Docetaxel

Pasculli, B., Barbano, R., Rendina, M., Fontana, A., Copetti, M., Mazza, T., Valori, V. M., Morritti, M., Maiello, E., Graziano, P., Murgo, R., Fazio, V. M., Esteller, M. & Parrella, P., Dec 1 2019, In : Scientific Reports. 9, 1, 14913.

Research output: Contribution to journalArticle

docetaxel
Area Under Curve
Breast Neoplasms
MicroRNAs
ROC Curve
Open Access
methylation
Methylation
cultured cells
genes
lungs
2018
3 Citations (Scopus)

Frequent NRG1 fusions in caucasian pulmonary mucinous adenocarcinoma predicted by Phospho-ErbB3 expression

Trombetta, D., Graziano, P., Scarpa, A., Sparaneo, A., Rossi, G., Rossi, A., Di Maio, M., Antonello, D., Mafficini, A., Fabrizio, F. P., Manzorra, M. C., Balsamo, T., Centra, F., Simbolo, M., Pantalone, A., Notarangelo, M., Parente, P., Dimitri, M. C. L., Bonfitto, A., Fiordelisi, F. & 6 others, Storlazzi, C. T., L'Abbate, A., Taurchini, M., Maiello, E., Fazio, V. M. & Muscarella, L. A., Jan 1 2018, In : Oncotarget. 9, 11, p. 9661-9671 11 p.

Research output: Contribution to journalArticle

Mucinous Adenocarcinoma
Fluorescence In Situ Hybridization
RNA Sequence Analysis
erbB-1 Genes
Chi-Square Distribution
2017
2 Citations (Scopus)

ALK and NRG1 Fusions Coexist in a Patient with Signet Ring Cell Lung Adenocarcinoma

Muscarella, L. A., Trombetta, D., Fabrizio, F. P., Scarpa, A., Fazio, V. M., Maiello, E., Rossi, A. & Graziano, P., Oct 2017, In : Journal of Thoracic Oncology. 12, 10, p. e161-e163

Research output: Contribution to journalArticle

1 Citation (Scopus)

A malignant inflammatory myofibroblastic tumor of the hypopharynx harboring the 3a/b variants of the EML4-ALK fusion gene

Muscarella, L. A., Rossi, G., Trombetta, D., La Torre, A., Candia, L., Mengoli, M. C., Sparaneo, A., Fazio, V. M. & Graziano, P., 2017, In : Oncology Letters. 13, 2, p. 593-598 6 p.

Research output: Contribution to journalArticle

Hypopharynx
Gene Fusion
Neoplasms
Neck
Head
17 Citations (Scopus)

Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer

Robertis, M., Loiacono, L., Fusilli, C., Poeta, M. L., Mazza, T., Sanchez, M., Marchionni, L., Signori, E., Lamorte, G., Vescovi, A. L., Garcia-Foncillas, J. & Fazio, V. M., Jan 1 2017, In : Clinical Cancer Research. 23, 1, p. 159-170 12 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Gene Expression
EphA2 Receptor
Neoplasms
Mutation
6 Citations (Scopus)

Gene Electrotransfer of Plasmid-Encoding IL-12 Recruits the M1 Macrophages and Antigen-Presenting Cells Inducing the Eradication of Aggressive B16F10 Murine Melanoma

Lampreht Tratar, U., Loiacono, L., Cemazar, M., Kamensek, U., Fazio, V. M., Sersa, G. & Signori, E., Jan 1 2017, In : Mediators of Inflammation. 2017, 5285890.

Research output: Contribution to journalArticle

Antigen-Presenting Cells
Interleukin-12
Melanoma
Plasmids
Macrophages
23 Citations (Scopus)

Keap1/Nrf2 pathway in kidney cancer: Frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma

Fabrizio, F. P., Costantini, M., Copetti, M., la Torre, A., Sparaneo, A., Fontana, A., Poeta, L., Gallucci, M., Sentinelli, S., Graziano, P., Parente, P., Pompeo, V., Salvo, L. D., Simone, G., Papalia, R., Picardo, F., Balsamo, T., Flammia, G. P., Trombetta, D., Pantalone, A. & 4 others, Kok, K., Paranita, F., Muscarella, L. A. & Fazio, V. M., Jan 1 2017, In : Oncotarget. 8, 7, p. 11187-11198 12 p.

Research output: Contribution to journalArticle

Kidney Neoplasms
Renal Cell Carcinoma
Methylation
Epigenomics
Genes
14 Citations (Scopus)

Stepwise analysis of MIR9 loci identifies MIR-9-5p to be involved in Oestrogen regulated pathways in breast cancer patients

Barbano, R., Pasculli, B., Rendina, M., Fontana, A., Fusilli, C., Copetti, M., Castellana, S., Valori, V. M., Morritti, M., Graziano, P., Luigi, C., Coco, M., Picardo, F., Mazza, T., Evron, E., Murgo, R., Maiello, E., Esteller, M., Fazio, V. M. & Parrella, P., Mar 27 2017, In : Scientific Reports. 7, 45283.

Research output: Contribution to journalArticle

Estrogens
Breast
Breast Neoplasms
MicroRNAs
Methylation
2016
2015
11 Citations (Scopus)

Competitive allele-specific TaqMan PCR (Cast-PCR) is a sensitive, specific and fast method for BRAF V600 mutation detection in Melanoma patients

Barbano, R., Pasculli, B., Coco, M., Fontana, A., Copetti, M., Rendina, M., Valori, V. M., Graziano, P., Maiello, E., Fazio, V. M. & Parrella, P., Dec 22 2015, In : Scientific Reports. 5, 18592.

Research output: Contribution to journalArticle

Melanoma
Alleles
Polymerase Chain Reaction
Mutation
Codon
1 Citation (Scopus)

The Post-Surgical Long-Term Behaviour of Lung Carcinoid Tumours

Tancredi, A., Muscarella, L. A., la Torre, A., Scaramuzzi, R., Valori, V. M., Fazio, V. M. & Scaramuzzi, G., Dec 1 2015, In : Indian Journal of Surgery. 77, 6, p. 481-485 5 p.

Research output: Contribution to journalArticle

Carcinoid Tumor
Lung
Recurrence
Mortality
Carboplatin
17 Citations (Scopus)

TRIM8 downregulation in glioma affects cell proliferation and it is associated with patients survival

Micale, L., Fusco, C., Fontana, A., Barbano, R., Augello, B., De Nittis, P., Copetti, M., Pellico, M. T., Mandriani, B., Cocciadiferro, D., Parrella, P., Fazio, V. M., Dimitri, L. M. C., D'Angelo, V., Novielli, C., Larizza, L., Daga, A. & Merla, G., Jun 16 2015, In : BMC Cancer. 15, 1, 470.

Research output: Contribution to journalArticle

Glioma
Down-Regulation
Cell Proliferation
Survival
3' Untranslated Regions
2014
47 Citations (Scopus)

A miRNA signature for defining aggressive phenotype and prognosis in gliomas

Barbano, R., Palumbo, O., Pasculli, B., Galasso, M., Volinia, S., D'Angelo, V., Icolaro, N., Coco, M., Dimitri, L., Graziano, P., Copetti, M., Valori, V. M., Maiello, E., Carella, M., Fazio, V. M. & Parrella, P., Oct 1 2014, In : PLoS One. 9, 10, e108950.

Research output: Contribution to journalArticle

MicroRNAs
microRNA
Glioma
prognosis
Phenotype
110 Citations (Scopus)

CD74-NRG1 fusions in lung adenocarcinoma

Fernandez-Cuesta, L., Plenker, D., Osada, H., Sun, R., Menon, R., Leenders, F., Ortiz-Cuaran, S., Peifer, M., Bos, M., Daßler, J., Malchers, F., Schöttle, J., Vogel, W., Dahmen, I., Koker, M., Ullrich, R. T., Wright, G. M., Russell, P. A., Wainer, Z., Solomon, B. & 31 others, Brambilla, E., Nagy-Mignotte, H., Moro-Sibilot, D., Brambilla, C. G., Lantuejoul, S., Altmüller, J., Becker, C., Nürnberg, P., Heuckmann, J. M., Stoelben, E., Petersen, I., Clement, J. H., Sänger, J., Muscarella, L. A., la Torre, A., Fazio, V. M., Lahortiga, I., Perera, T., Ogata, S., Parade, M., Brehmer, D., Vingron, M., Heukamp, L. C., Buettner, R., Zander, T., Wolf, J., Perner, S., Ansén, S., Haas, S. A., Yatabe, Y. & Thomas, R. K., 2014, In : Cancer Discovery. 4, 4, p. 415-422 8 p.

Research output: Contribution to journalArticle

Mucinous Adenocarcinoma
Gene Fusion
Neoplasms
Phosphatidylinositol 3-Kinases
Transcriptome
5 Citations (Scopus)

Establishment and genetic characterization of ANGM-CSS, a novel, immortal cell line derived from a human glioblastoma multiforme

Notarangelo, A., Trombetta, D., D'Angelo, V., Parrella, P., Palumbo, O., Tiziana Storlazzi, C., Impera, L., Muscarella, L. A., La Torre, A., Affuso, A., Fazio, V. M., Carella, M. & Zelante, L., Mar 2014, In : International Journal of Oncology. 44, 3, p. 717-724 8 p.

Research output: Contribution to journalArticle

Glioblastoma
Cell Line
Cytogenetic Analysis
Karyotype
Heterografts
25 Citations (Scopus)

Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients

Parrella, P., Barbano, R., Pasculli, B., Fontana, A., Copetti, M., Valori, V. M., Poeta, M. L., Perrone, G., Righi, D., Castelvetere, M., Coco, M., Balsamo, T., Morritti, M., Pellegrini, F., Onetti-Muda, A., Maiello, E., Murgo, R. & Fazio, V. M., Jun 4 2014, In : Molecular Cancer. 13, 1, 142.

Research output: Contribution to journalArticle

MicroRNAs
Breast Neoplasms
Neoplasm Metastasis
Disease Progression
Neoplasms
9 Citations (Scopus)

Molecular dissection of the VHL gene in solitary capillary hemangioblastoma of the central nervous system

Muscarella, L. A., La Torre, A., Faienza, A., Catapano, D., Bisceglia, M., D'Angelo, V., Parrella, P., Coco, M., Fini, G., Tancredi, A., Zelante, L., Fazio, V. M. & D'Agruma, L., Jan 2014, In : Journal of Neuropathology and Experimental Neurology. 73, 1, p. 50-58 9 p.

Research output: Contribution to journalArticle

Hemangioblastoma
Dissection
Central Nervous System
von Hippel-Lindau Disease
Genes

The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation [EMBO Mol Med, 5, (2013) 1523-1536, DOI: 10.1002/emmm.201302847]

Lucá, R., Averna, M., Zalfa, F., Vecchi, M., Bianchi, F., La Fata, G., Del Nonno, F., Nardacci, R., Bianchi, M., Nuciforo, P., Munck, S., Parrella, P., Moura, R., Signori, E., Alston, R., Kuchnio, A., Giulia Farace, M., Michele Fazio, V., Piacentini, M., De Strooper, B. & 7 others, Achsel, T., Neri, G., Neven, P., Evans, D. G., Carmeliet, P., Mazzone, M. & Bagni, C., 2014, In : EMBO Molecular Medicine. 6, 4, p. 567-568 2 p.

Research output: Contribution to journalArticle

2013
52 Citations (Scopus)

Aberrant Keap1 methylation in breast cancer and association with clinicopathological features

Barbano, R., Muscarella, L. A., Pasculli, B., Valori, V. M., Fontana, A., Coco, M., la Torre, A., Balsamo, T., Poeta, M. L., Marangi, G. F., Maiello, E., Castelvetere, M., Pellegrini, F., Murgo, R., Fazio, V. M. & Parrella, P., Jan 2013, In : Epigenetics. 8, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

Methylation
Breast Neoplasms
Triple Negative Breast Neoplasms
Breast
docetaxel
20 Citations (Scopus)

Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

Brait, M., Maldonado, L., Noordhuis, M., Begum, S., Loyo, M., Poeta, M. L., Barbosa, A., Fazio, V. M., Angioli, R., Rabitti, C., Marchionni, L., de Graeff, P., van der Zee, A. G. J., Wisman, G. B. A., Sidransky, D. & Hoque, M. O., Sep 27 2013, In : PLoS One. 8, 9, e70878.

Research output: Contribution to journalArticle

Methylation
ovarian neoplasms
methylation
Ovarian Neoplasms
Hazards
20 Citations (Scopus)

Electroporation in DNA vaccination protocols against cancer

Chiarella, P., Fazio, V. M. & Signori, E., Mar 2013, In : Current Drug Metabolism. 14, 3, p. 291-299 9 p.

Research output: Contribution to journalArticle

DNA Vaccines
Electroporation
Tumors
Vaccination
Neoplasm Antigens
10 Citations (Scopus)

Hyaluronidase contributes to early inflammatory events induced by electrotransfer in mouse skeletal muscle

Chiarella, P., De Santis, S., Fazio, V. M. & Signori, E., Apr 1 2013, In : Human Gene Therapy. 24, 4, p. 406-416 11 p.

Research output: Contribution to journalArticle

Hyaluronoglucosaminidase
Skeletal Muscle
DNA Vaccines
Cytokines
Muscles
8 Citations (Scopus)

In vivo DNA electrotransfer for immunotherapy of cancer and neurodegenerative diseases

Fioretti, D., Iurescia, S., Fazio, V. M. & Rinaldi, M., Mar 2013, In : Current Drug Metabolism. 14, 3, p. 279-290 12 p.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Electroporation
Neurodegenerative Diseases
Immunotherapy
Genes

Prevention is better than cure

Signori, E. & Fazio, V. M., Jun 2013, In : EBR - European Biopharmaceutical Review. SUMMER, p. 30-32 3 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation

Lucá, R., Averna, M., Zalfa, F., Vecchi, M., Bianchi, F., Fata, G. L., Del Nonno, F., Nardacci, R., Bianchi, M., Nuciforo, P., Munck, S., Parrella, P., Moura, R., Signori, E., Alston, R., Kuchnio, A., Farace, M. G., Fazio, V. M., Piacentini, M., De Strooper, B. & 7 others, Achsel, T., Neri, G., Neven, P., Evans, D. G., Carmeliet, P., Mazzone, M. & Bagni, C., Oct 2013, In : EMBO Molecular Medicine. 5, 10, p. 1523-1536 14 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Neoplasm Metastasis
Messenger RNA
Fragile X Syndrome
Neoplasms
33 Citations (Scopus)

The genetics of sports injuries and athletic performance

Maffulli, N., Margiotti, K., Longo, U. G., Loppini, M., Fazio, V. M. & Denaro, V., Jul 2013, In : Muscles, Ligaments and Tendons Journal. 3, 3, p. 173-189 17 p.

Research output: Contribution to journalArticle

Athletic Performance
Athletic Injuries
Genes
Tendon Injuries
Wounds and Injuries
3 Citations (Scopus)

VHL gene alterations in Italian patients with isolated renal cell carcinomas

Muscarella, L. A., D'Agruma, L., la Torre, A., Gigante, M., Coco, M., Parrella, P., Battaglia, M., Carrieri, G., Carella, M., Zelante, L., Fazio, V. M., Gesualdo, L. & Ranieri, E., Apr 2013, In : International Journal of Biological Markers. 28, 2, p. 208-215 8 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Genes
Cells
Tumors
Loss of Heterozygosity
2012
2 Citations (Scopus)

Aberrant genes promoter methylation in neural crest-derived tumors

La Torre, A., Muscarella, L. A., Parrella, P., Balsamo, T., Bisceglia, M., Valori, V. M., La Torre, A., Barbano, R., Perrella, E., Poeta, M. L., Melchionda, G., Merla, G., Maiello, E., Pellicano, R. & Fazio, V. M., Oct 2012, In : International Journal of Biological Markers. 27, 4

Research output: Contribution to journalArticle

Methylation
Tumors
Genes
Carcinoid Tumor
Neoplasms
15 Citations (Scopus)

Aberrant promoter methylation of beta-1,4 galactosyltransferase 1 as potential cancer-specific biomarker of colorectal tumors

Poeta, M. L., Massi, E., Parrella, P., Pellegrini, P., De Robertis, M., Copetti, M., Rabitti, C., Perrone, G., Muda, A. O., Molinari, F., Zanellato, E., Crippa, S., Caputo, D., Caricato, M., Frattini, M., Coppola, R. & Fazio, V. M., Dec 2012, In : Genes Chromosomes and Cancer. 51, 12, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

N-Acetyllactosamine Synthase
Tumor Biomarkers
Methylation
Colorectal Neoplasms
Confidence Intervals
6 Citations (Scopus)

BCR/ABL1 fusion transcripts generated from alternative splicing: Implications for future targeted therapies in Ph+ leukaemias

Chiarella, P., Summa, V., de Santis, S., Signori, E., Picardi, E., Pesole, G., Saglio, G. & Fazio, V. M., Jun 2012, In : Current Molecular Medicine. 12, 5, p. 547-565 19 p.

Research output: Contribution to journalArticle

Alternative Splicing
Biomarkers
Leukemia
Phosphotransferases
Fusion reactions
12 Citations (Scopus)
Lymphocytes
Lymphocyte Subsets
Non-Small Cell Lung Carcinoma
Hydrocortisone
Melatonin
34 Citations (Scopus)

Epitope-driven DNA vaccine design employing immunoinformatics against B-cell lymphoma: A biotech's challenge

Iurescia, S., Fioretti, D., Fazio, V. M. & Rinaldi, M., Jan 2012, In : Biotechnology Advances. 30, 1, p. 372-383 12 p.

Research output: Contribution to journalArticle

Epitopes
DNA Vaccines
Vaccines
B-Cell Lymphoma
Cells

Erratum to " DNA vaccines for B-cell lymphomas: Towards personalised medicine and tailored drugs" [J. Biotechnol. 150S (2010) S99-S100]

Iurescia, S., Fioretti, D., Pierimarchi, P., Signori, E., Zonfrillo, M., Fazio, V. M. & Rinaldi, M., Aug 31 2012, In : Journal of Biotechnology. 160, 3-4, p. 273 1 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Hormone and cytokine circadian alteration in non-small cell lung cancer patients

Mazzoccoli, G., Sothern, R. B., Francavilla, M., Giuliani, F., Carughi, S., Muscarella, L. A., Fazio, V. M., Parrella, P., Vinciguerra, M. & Tarquini, R., Jul 2012, In : International Journal of Immunopathology and Pharmacology. 25, 3, p. 691-702 12 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Growth Hormone
Hormones
Cytokines
Hydrocortisone
653 Citations (Scopus)

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

Peifer, M., Fernández-Cuesta, L., Sos, M. L., George, J., Seidel, D., Kasper, L. H., Plenker, D., Leenders, F., Sun, R., Zander, T., Menon, R., Koker, M., Dahmen, I., Müller, C., Di Cerbo, V., Schildhaus, H. U., Altmüller, J., Baessmann, I., Becker, C., De Wilde, B. & 73 others, Vandesompele, J., Böhm, D., Ansén, S., Gabler, F., Wilkening, I., Heynck, S., Heuckmann, J. M., Lu, X., Carter, S. L., Cibulskis, K., Banerji, S., Getz, G., Park, K. S., Rauh, D., Grütter, C., Fischer, M., Pasqualucci, L., Wright, G., Wainer, Z., Russell, P., Petersen, I., Chen, Y., Stoelben, E., Ludwig, C., Schnabel, P., Hoffmann, H., Muley, T., Brockmann, M., Engel-Riedel, W., Muscarella, L. A., Fazio, V. M., Groen, H., Timens, W., Sietsma, H., Thunnissen, E., Smit, E., Heideman, D. A. M., Snijders, P. J. F., Cappuzzo, F., Ligorio, C., Damiani, S., Field, J., Solberg, S., Brustugun, O. T., Lund-Iversen, M., Sänger, J., Clement, J. H., Soltermann, A., Moch, H., Weder, W., Solomon, B., Soria, J. C., Validire, P., Besse, B., Brambilla, E., Brambilla, C., Lantuejoul, S., Lorimier, P., Schneider, P. M., Hallek, M., Pao, W., Meyerson, M., Sage, J., Shendure, J., Schneider, R., Büttner, R., Wolf, J., Nürnberg, P., Perner, S., Heukamp, L. C., Brindle, P. K., Haas, S. & Thomas, R. K., Oct 2012, In : Nature Genetics. 44, 10, p. 1104-1110 7 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Genome
Mutation
Genes
Histone Code
2011
7 Citations (Scopus)

Antiphase signalling in the neuroendocrine-immune system in healthy humans

Mazzoccoli, G., Muscarella, L. A., Fazio, V. M., Piepoli, A., Pazienza, V., Dagostino, M. P., Giuliani, F., Polyakova, V. O. & Kvetnoy, I., Jul 2011, In : Biomedicine and Pharmacotherapy. 65, 4, p. 275-279 5 p.

Research output: Contribution to journalArticle

Neurosecretory Systems
Lymphocyte Subsets
Melatonin
Hydrocortisone
Immune System
5 Citations (Scopus)

Bilateral consecutive rupture of the quadriceps tendon in a man with BstUI polymorphism of the COL5A1 gene

Longo, U. G., Fazio, V. M., Poeta, M. L., Rabitti, C., Franceschi, F., Maffulli, N. & Denaro, V., Aug 2011, In : Knee Surgery, Sports Traumatology, Arthroscopy. 19, 8, p. 1404-1405 2 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Comparison and critical analysis of robotized technology for monoclonal antibody high-throughput production

Chiarella, P., Leuener, M., Fasci, C., de Marco, A., Santini, M. P., Fazio, V. M. & Sawyer, A. M., Mar 2011, In : Biotechnology Progress. 27, 2, p. 571-576 6 p.

Research output: Contribution to journalArticle

Hybridomas
Immunization
Monoclonal Antibodies
Technology
Antigens
6 Citations (Scopus)

Design and pre-clinical development of epitope-based DNA vaccines against B-cell lymphoma

Iurescia, S., Fioretti, D., Fazio, V. M. & Rinaldi, M., Oct 2011, In : Current Gene Therapy. 11, 5, p. 414-422 9 p.

Research output: Contribution to journalArticle

Cancer Vaccines
DNA Vaccines
B-Cell Lymphoma
Epitopes
Vaccines
79 Citations (Scopus)

Frequent epigenetics inactivation of KEAP1 gene in non-small cell lung cancer

Muscarella, L. A., Parrella, P., D'Alessandro, V., la Torre, A., Barbano, R., Fontana, A., Tancredi, A., Guarnieri, V., Balsamo, T., Coco, M., Copetti, M., Pellegrini, F., de Bonis, P., Bisceglia, M., Scaramuzzi, G., Maiello, E., Valori, V. M., Merla, G., Vendemiale, G. & Fazio, V. M., Jun 2011, In : Epigenetics. 6, 6, p. 710-719 10 p.

Research output: Contribution to journalArticle

Gene Silencing
Epigenomics
Non-Small Cell Lung Carcinoma
Methylation
Disease Progression
12 Citations (Scopus)
Somatostatin Receptors
Lung Neoplasms
Real-Time Polymerase Chain Reaction
Gene Expression
Messenger RNA
27 Citations (Scopus)

High RAD51 mRNA expression characterize estrogen receptor-positive/ progesteron receptor-negative breast cancer and is associated with patient's outcome

Barbano, R., Copetti, M., Perrone, G., Pazienza, V., Muscarella, L. A., Balsamo, T., Storlazzi, C. T., Ripoli, M., Rinaldi, M., Valori, V. M., Latiano, T. P., Maiello, E., Stanziale, P., Carella, M., Mangia, A., Pellegrini, F., Bisceglia, M., Muda, A. O., Altomare, V., Murgo, R. & 2 others, Fazio, V. M. & Parrella, P., Aug 1 2011, In : International Journal of Cancer. 129, 3, p. 536-545 10 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Estrogen Receptors
Breast Neoplasms
Messenger RNA
Neoplasms
58 Citations (Scopus)

Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome

Muscarella, L. A., Barbano, R., D'Angelo, V., Copetti, M., Coco, M., Balsamo, T., la Torre, A., Notarangelo, A., Troiano, M., Parisi, S., Icolaro, N., Catapano, D., Valori, V. M., Pellegrini, F., Merla, G., Carella, M., Fazio, V. M. & Parrella, P., Mar 2011, In : Epigenetics. 6, 3, p. 317-325 9 p.

Research output: Contribution to journalArticle

Glioma
Methylation
temozolomide
decitabine
Polymerase Chain Reaction
229 Citations (Scopus)

The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies

Robertis, M., Massi, E., Poeta, M., Carotti, S., Morini, S., Cecchetelli, L., Signori, E. & Fazio, V., 2011, In : Journal of Carcinogenesis. 10, 9.

Research output: Contribution to journalArticle

Azoxymethane
Dextran Sulfate
Colorectal Neoplasms
Colon
Carcinogenesis
2010
9 Citations (Scopus)

Antigenic features of protein carriers commonly used in immunisation trials

Chiarella, P., Edelmann, B., Fazio, V. M., Sawyer, A. M. & de Marco, A., 2010, In : Biotechnology Letters. 32, 9, p. 1215-1221 7 p.

Research output: Contribution to journalArticle

Protein Disulfide-Isomerases
Immunization
Carrier Proteins
Antigens
Proteins