Over the past two decades, research in animal models has indicated that α-melanocyte-stimulating hormone (α-MSH) has potent anti-inflammatory properties. Furthermore, recent data show that the peptide has antimicrobial effects and probably contributes to innate immunity. α-MSH, which is produced by many extrapituitary human cells, should no longer be considered solely a pituitary hormone; rather, it should be viewed as a ubiquitous modulatory peptide.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism