β-TG and plasma catecholamines levels after sympathetic stimuli in hypertensives and patients with peripheral vascular disease

M. Catalano, U. Russo, S. Belletti, F. Colombo, A. Belloni, G. Del Rosso, F. Lombardi, A. Libretti

Research output: Contribution to journalArticle

Abstract

The influence of the sympathetic nervous system on platelet functions in vivo is still controversial. The aims of our study were to compare the response to various sympathetic stimuli in normal subjects and in patients with essential hypertension (HT) or peripheral vascular disease (PVD) and to evaluate any corelations among plasma levels of catecholamines, beta-thromboglobulin (β-TG) and platelet factor 4 (PF4). In basal conditions β-TG and PF4 values in the HT patients were higher than those observed in the controls of the same age but lower than those of the PVD patients. Although the different sympathetic stimuli (90° tilting, handgrip, treadmill test, bicycle test) caused a significant increase of the plasma epineprhine (E) and norepinephrine (NE) levels, they did not modify the β-TG and PF4 levels in any of the groups studied. The platelet activation indices, therefore, regardless of the basal values, do not seem to be influenced by sympathetic stimulation.

Original languageEnglish
Pages (from-to)383-385
Number of pages3
JournalThrombosis and Haemostasis
Volume63
Issue number3
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Hematology

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    Catalano, M., Russo, U., Belletti, S., Colombo, F., Belloni, A., Del Rosso, G., Lombardi, F., & Libretti, A. (1990). β-TG and plasma catecholamines levels after sympathetic stimuli in hypertensives and patients with peripheral vascular disease. Thrombosis and Haemostasis, 63(3), 383-385.