109. Comparison of plasma lipoprotein (a) levels between individuals attending a metabolic ward with and without a history of ischémie stroke

M. Margaglione, E. Grandone, E. Celentano, G. Vecchione, G. Cappucci, M. Grilli, F. P. Mancini, A. Postiglione, S. Panico, G. Di Minno

Research output: Contribution to journalArticle

Abstract

Objectives. To evaluate the ability of lipoprotein(a), Lp(a), to discriminate subjects with a stroke history, as compared to that of plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (t-PA). Design. Cross-sectional study. Subjects from a metabolic ward. Participants. A total of 210 subjects (108 men, 102 women, mean age 63.8 yrs, range 31-86) provided plasma and DNA samples for the study. One hundred and one of these (51 males, 50 females) had a history of ischémie stroke. The one hundred and nine subjects who did not have a stroke history, were compared with those with such a history, for major risk factors for ischémie events. Results. Mean plasma t-PA and PAI-1 levels significantly (p50 mg/dl were more common among those with a stroke history (8 with vs 1 without, p50 mg/dl) plasma levels of the lipoprotein.

Original languageEnglish
Pages (from-to)33-34
Number of pages2
JournalFibrinolysis
Volume10
Issue numberSUPPL. 1
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Hematology

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