[123I]FP-CIT striatal binding in early Parkinson's disease patients with tremor vs. akinetic-rigid onset

Ioannis U. Isaias, Riccardo Benti, Roberto Cilia, Margherita Canesi, Giorgio Marotta, Paolo Gerundini, Gianni Pezzoli, Angelo Antonini

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

We performed [123I]FP-CIT/SPECT in 20 drug-naive Parkinson's disease (PD) patients, 10 with unilateral akinesia/rigidity at onset (arPD) and 10 with additional tremor-at-rest (tPD), to evaluate whether resting tremor at onset is associated with differences in striatal dopamine transporter binding. Patients of the two cohorts were matched for age, disease duration (

Original languageEnglish
Pages (from-to)1499-1502
Number of pages4
JournalNeuroReport
Volume18
Issue number14
DOIs
Publication statusPublished - Sep 2007

Fingerprint

Corpus Striatum
Tremor
Parkinson Disease
Dopamine Plasma Membrane Transport Proteins
Single-Photon Emission-Computed Tomography
Pharmaceutical Preparations
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane
Parkinson Disease 10

Keywords

  • [I]FP-CIT
  • Dopamine transporter
  • Parkinsons disease
  • SPECT
  • Tremor-at-rest

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

[123I]FP-CIT striatal binding in early Parkinson's disease patients with tremor vs. akinetic-rigid onset. / Isaias, Ioannis U.; Benti, Riccardo; Cilia, Roberto; Canesi, Margherita; Marotta, Giorgio; Gerundini, Paolo; Pezzoli, Gianni; Antonini, Angelo.

In: NeuroReport, Vol. 18, No. 14, 09.2007, p. 1499-1502.

Research output: Contribution to journalArticle

Isaias, Ioannis U. ; Benti, Riccardo ; Cilia, Roberto ; Canesi, Margherita ; Marotta, Giorgio ; Gerundini, Paolo ; Pezzoli, Gianni ; Antonini, Angelo. / [123I]FP-CIT striatal binding in early Parkinson's disease patients with tremor vs. akinetic-rigid onset. In: NeuroReport. 2007 ; Vol. 18, No. 14. pp. 1499-1502.
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