12q13 fragility in a family with recurrent spontaneous abortions: Expression of the fragile site under different culture conditions

D. Giardino, D. Bettio, G. Simoni

Research output: Contribution to journalArticle

Abstract

A fragile site at the 12q13 band was found in metaphases from lymphocyte cultures of three members of a family. A comparison of the frequency and expression of the fragile site was carried out on cells cultured in RPM-I 1640 with and without BrdU and in 199 media. The fragile site was not typically folate-sensitive, being expressed in standard medium as well as in cultures after exposure to BrdU.

Original languageEnglish
Pages (from-to)88-91
Number of pages4
JournalAnnales de Genetique
Volume33
Issue number2
Publication statusPublished - 1990

Keywords

  • Chromosome 12
  • Culture conditions
  • Fragile site

ASJC Scopus subject areas

  • Genetics

Fingerprint Dive into the research topics of '12q13 fragility in a family with recurrent spontaneous abortions: Expression of the fragile site under different culture conditions'. Together they form a unique fingerprint.

  • Cite this