A fragile site at the 12q13 band was found in metaphases from lymphocyte cultures of three members of a family. A comparison of the frequency and expression of the fragile site was carried out on cells cultured in RPM-I 1640 with and without BrdU and in 199 media. The fragile site was not typically folate-sensitive, being expressed in standard medium as well as in cultures after exposure to BrdU.
|Number of pages||4|
|Journal||Annales de Genetique|
|Publication status||Published - 1990|
- Chromosome 12
- Culture conditions
- Fragile site
ASJC Scopus subject areas