Abstract
Current classification criteria for definite Antiphospholipid Syndrome (APS) require the use of three laboratory assays to detect antiphospholipid antibodies (aCL, anti-β2GPI and LA) in the presence of at least one of the two major clinical manifestations (i.e. thrombosis or pregnancy morbidity) of the syndrome. However, several other autoantibodies shown to be directed to other proteins or their complex with phospholipids have been proposed to be relevant to APS but their clinical utility and their diagnostic value remains elusive. This report summarizes the findings, conclusions and recommendations of the "APS Task Force 3-Laboratory Diagnostics and Trends" meeting that took place during the 14th International Congress on Antiphospholipid Antibodies (APLA 2013, September 18-21, Rio de Janeiro, RJ, Brazil).
| Original language | English |
|---|---|
| Pages (from-to) | 917-930 |
| Number of pages | 14 |
| Journal | Autoimmunity Reviews |
| Volume | 13 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2014 |
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Keywords
- ACL
- Antiprothrombin antibodies
- Domain I
- IgA
- Lupus anticoagulant
- Risk
ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
- Medicine(all)
Cite this
14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends. / Bertolaccini, Maria Laura; Amengual, Olga; Andreoli, Laura; Atsumi, Tatsuya; Chighizola, Cecilia B.; Forastiero, Ricardo; de Groot, Philip; Lakos, Gabriella; Lambert, Marc; Meroni, Pierluigi; Ortel, Thomas L.; Petri, Michelle; Rahman, Anisur; Roubey, Robert; Sciascia, Savino; Snyder, Melissa; Tebo, Anne E.; Tincani, Angela; Willis, Rohan.
In: Autoimmunity Reviews, Vol. 13, No. 9, 2014, p. 917-930.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - 14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends
AU - Bertolaccini, Maria Laura
AU - Amengual, Olga
AU - Andreoli, Laura
AU - Atsumi, Tatsuya
AU - Chighizola, Cecilia B.
AU - Forastiero, Ricardo
AU - de Groot, Philip
AU - Lakos, Gabriella
AU - Lambert, Marc
AU - Meroni, Pierluigi
AU - Ortel, Thomas L.
AU - Petri, Michelle
AU - Rahman, Anisur
AU - Roubey, Robert
AU - Sciascia, Savino
AU - Snyder, Melissa
AU - Tebo, Anne E.
AU - Tincani, Angela
AU - Willis, Rohan
PY - 2014
Y1 - 2014
N2 - Current classification criteria for definite Antiphospholipid Syndrome (APS) require the use of three laboratory assays to detect antiphospholipid antibodies (aCL, anti-β2GPI and LA) in the presence of at least one of the two major clinical manifestations (i.e. thrombosis or pregnancy morbidity) of the syndrome. However, several other autoantibodies shown to be directed to other proteins or their complex with phospholipids have been proposed to be relevant to APS but their clinical utility and their diagnostic value remains elusive. This report summarizes the findings, conclusions and recommendations of the "APS Task Force 3-Laboratory Diagnostics and Trends" meeting that took place during the 14th International Congress on Antiphospholipid Antibodies (APLA 2013, September 18-21, Rio de Janeiro, RJ, Brazil).
AB - Current classification criteria for definite Antiphospholipid Syndrome (APS) require the use of three laboratory assays to detect antiphospholipid antibodies (aCL, anti-β2GPI and LA) in the presence of at least one of the two major clinical manifestations (i.e. thrombosis or pregnancy morbidity) of the syndrome. However, several other autoantibodies shown to be directed to other proteins or their complex with phospholipids have been proposed to be relevant to APS but their clinical utility and their diagnostic value remains elusive. This report summarizes the findings, conclusions and recommendations of the "APS Task Force 3-Laboratory Diagnostics and Trends" meeting that took place during the 14th International Congress on Antiphospholipid Antibodies (APLA 2013, September 18-21, Rio de Janeiro, RJ, Brazil).
KW - ACL
KW - Antiprothrombin antibodies
KW - Domain I
KW - IgA
KW - Lupus anticoagulant
KW - Risk
UR - http://www.scopus.com/inward/record.url?scp=84922593999&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84922593999&partnerID=8YFLogxK
U2 - 10.1016/j.autrev.2014.05.001
DO - 10.1016/j.autrev.2014.05.001
M3 - Article
C2 - 24824074
AN - SCOPUS:84922593999
VL - 13
SP - 917
EP - 930
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
SN - 1568-9972
IS - 9
ER -