16th International Congress on Antiphospholipid Antibodies Task Force Report on Obstetric Antiphospholipid Syndrome

Guilherme R. de Jesús, Ashley E. Benson, Cecilia B. Chighizola, Savino Sciascia, David W. Branch

Research output: Contribution to journalArticlepeer-review

Abstract

Obstetric antiphospholipid syndrome (APS) remains a clinical challenge for practitioners, with several controversial points that have not been answered so far. This Obstetric APS Task Force met on the 16th International Congress on Antiphospholipid Antibodies in Manchester, England, to discuss about treatment, diagnostic and clinical aspects of the disease. This report will address evidence-based medicine related to obstetric APS, including limitations on our current management, the relationship between antibodies against domain 1 of β2GPI and obstetric morbidity, hydroxychloroquine use in patients with obstetric APS and factors associated with thrombosis after obstetric APS. Finally, future directions for better understanding this complex condition are also reported by the Task Force coordinators.

Original languageEnglish
Pages (from-to)1601-1615
Number of pages15
JournalLupus
Volume29
Issue number12
DOIs
Publication statusPublished - Oct 1 2020

Keywords

  • anti-β2GPI domain 1 antibodies
  • antiphospholipid antibodies
  • Antiphospholipid syndrome
  • hydroxychloroquine
  • thrombosis

ASJC Scopus subject areas

  • Rheumatology

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