18F-DOPA Uptake of Developmental Venous Anomalies in Children With Brain Tumors

Giovanni Morana, Arnoldo Piccardo, Maria Luisa Garrè, Manlio Cabria, Andrea Rossi

Research output: Contribution to journalArticlepeer-review


ABSTRACT: We report the finding of increased F-3,4-dihydroxyphenylalanine uptake of the brain parenchyma adjacent to developmental venous anomalies, incidentally discovered in 3 pediatric patients with diffusely infiltrating gliomas. One patient presented 3 developmental venous anomalies located distant from the tumor, whereas in the remaining 2 patients, the vascular anomalies were inside the tumoral area mimicking a focal area of increased tumor metabolism. In the setting of brain tumor imaging, focal increased F-3,4-dihydroxyphenylalanine uptake should be carefully interpreted in light of MRI findings, and nuclear medicine physicians should be aware of any incidental minor vascular abnormality for proper interpretation of PET data.

Original languageEnglish
JournalClinical Nuclear Medicine
Publication statusAccepted/In press - Feb 24 2016

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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