Abstract
Background. We used [18F]FDG and PET in patients with obsessive-compulsive disorder (OCD) to evaluate cerebral metabolic involvement before and after treatment with serotonin-specific reuptake inhibitors. Method. In 11 untreated, drug-free adults, regional cerebral metabolic rate for glucose (rCMRglu) was compared with that of 15 age-matched normal controls. Results. rCMRglu values were significantly increased in the cingulate cortex, thalamus and pallidum/putamen complex. After treatment a significant improvement in obsessive-compulsive symptoms on the Y-BOC scale (t=3.59, P
Original language | English |
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Pages (from-to) | 244-250 |
Number of pages | 7 |
Journal | British Journal of Psychiatry |
Volume | 166 |
Issue number | FEB. |
Publication status | Published - 1995 |
ASJC Scopus subject areas
- Psychiatry and Mental health
- Neuroscience(all)