2-(substituted)amino-2,8-diazaspiro[4,5]decan-1,3-diones as potential muscarinic agonists: Synthesis, modeling and binding studies

D. Barlocco, F. Fanelli, G. Cignarella, S. Villa, F. Cattabeni, W. Balduini, M. Cimino, P. G. De Benedetti

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)129-143
Number of pages15
JournalDrug Design and Discovery
Issue number2
Publication statusPublished - 1996


  • 2,8-disubstituted-2,8-diazaspiro[4,5]decan-1,3-diones
  • Molecular dynamics
  • Muscarinic agonists
  • RS-86
  • Theoretical molecular descriptors

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery

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