2016 Update of the Italian Pediatric Society Guidelines for Management of Fever in Children

Elena Chiappini, Elisabetta Venturini, Giulia Remaschi, Nicola Principi, Riccardo Longhi, Pier Angelo Tovo, Paolo Becherucci, Francesca Bonsignori, Susanna Esposito, Filippo Festini, Luisa Galli, Bice Lucchesi, Alessandro Mugelli, Gian Luigi Marseglia, Maurizio de Martino, Italian Pediatric Society Panel for the Management of Fever in Children

Research output: Contribution to journalArticlepeer-review


Objective To review new scientific evidence to update the Italian guidelines for managing fever in children as drafted by the panel of the Italian Pediatric Society. Study design Relevant publications in English and Italian were identified through search of MEDLINE and the Cochrane Database of Systematic Reviews from May 2012 to November 2015. Results Previous recommendations are substantially reaffirmed. Antipyretics should be administered with the purpose to control the child's discomfort. Antipyretics should be administered orally; rectal administration is discouraged except in the setting of vomiting. Combined use of paracetamol and ibuprofen is discouraged, considering risk and benefit. Antipyretics are not recommended preemptively to reduce the incidence of fever and local reactions in children undergoing vaccination, or in attempt to prevent febrile convulsions in children. Ibuprofen and paracetamol are not contraindicated in children who are febrile with asthma, with the exception of known cases of paracetamol- or nonsteroidal anti-inflammatory drug-induced asthma. Conclusions Recent medical literature leads to reaffirmation of previous recommendations for use of antipyretics in children who are febrile.

Original languageEnglish
Pages (from-to)177-183.e1
JournalJournal of Pediatrics
Publication statusPublished - Jan 1 2017


  • antipyretic
  • children
  • fever
  • thermometer

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of '2016 Update of the Italian Pediatric Society Guidelines for Management of Fever in Children'. Together they form a unique fingerprint.

Cite this