2,3,7,8-Tetrachlorodibenzo-p-dioxin toxic effects and tissue levels in animals from the contaminated area of seveso, Italy

R. Fanelli, M. P. Bertoni, M. G. Castelli, C. Chiabrando, G. P. Martelli, A. Noseda, S. Garattini, C. Binaghi, V. Marazza, F. Pezza

Research output: Contribution to journalArticlepeer-review

Abstract

After the environmental contamination by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the area of Seveso, Italy, thousands of small domestic animals (mainly rabbits and poultry) died within a few weeks. Autopsies on dead animals showed various pathological signs, such as hepatic lesions and haemorrhage. TCDD was monitored in animal tissues by gas chromatography-mass fragmentography; rabbit liver levels corresponded fairly well to soil contamination, which indicated that this species can be used as a tool for tracking the presence of TCDD in the environment.

Original languageEnglish
Pages (from-to)569-577
Number of pages9
JournalArchives of Environmental Contamination and Toxicology
Volume9
Issue number5
DOIs
Publication statusPublished - Sep 1980

ASJC Scopus subject areas

  • Toxicology
  • Environmental Chemistry
  • Environmental Science(all)

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