24-month follow-up of multiple sclerosis patients treated with cyclophosphamide

E. Millefiorini, M. Di Giovanni, S. Bernardi, M. G. Grasso, A. Di Giampietro, D. Gambi

Research output: Contribution to journalArticlepeer-review


15 patients with remitting-progressive multiple sclerosis received a course of intravenous cyclophosphamide followed by a booster dose every 60 days for 2 years. There were no severe short or medium term side effects. Half of the patients presented clinical stabilization and substantially unchanged Kurtzke rating at 2 year follow-up. Since the aim was stabilization only, our findings argue for continuation of the study in young patients with very short shift.

Original languageEnglish
Pages (from-to)605-607
Number of pages3
JournalItalian Journal of Neurological Sciences
Issue number6
Publication statusPublished - Dec 1990


  • Cyclophosphamide
  • multiple sclerosis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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