3 Tesla is twice as sensitive as 1.5 Tesla magnetic resonance imaging in the assessment of diffuse axonal injury in traumatic brain injury patients

Luccichenti Giacomo, Giugni Elisabetta, Péran Patrice, Cherubini Andrea, Barba Carmen, Bivona Umberto, Formisano Rita, Sabatini Umberto

Research output: Contribution to journalArticle

Abstract

Diffuse axonal injury (DAI), associated with deafferentation and functional rearrangement, probably plays a role in the chronic phase of traumatic brain injury (TBI). DAI with a haemorrhagic component can be quantified using magnetic resonance imaging (MRI) thanks to the iron-based susceptibility effect of haemosiderin, which increases with magnetic field strength. The aim of this work was to compare conventional 1.5 Tesla and 3 Tesla MRI in the assessment of DAI in TBI patients. Eighteen TBI patients were submitted, in random order, to a 1.5T and a 3T MRI examination using standard gradient echo sequences. Both scans were always performed on the same day. DAI lesions with a haemorrhagic component were manually segmented and classified by anatomical location. The Wilcoxon and ANOVA tests were used for statistical analysis, significance being set at p

Original languageEnglish
Pages (from-to)109-114
Number of pages6
JournalFunctional Neurology
Volume25
Issue number2
Publication statusPublished - Apr 2010

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Diffuse Axonal Injury
Magnetic Resonance Imaging
Hemosiderin
Magnetic Fields
Analysis of Variance
Iron
Traumatic Brain Injury

Keywords

  • Diffuse axonal injury
  • Gradient echo sequences
  • High-field magnetic resonance
  • Traumatic brain injury

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

3 Tesla is twice as sensitive as 1.5 Tesla magnetic resonance imaging in the assessment of diffuse axonal injury in traumatic brain injury patients. / Giacomo, Luccichenti; Elisabetta, Giugni; Patrice, Péran; Andrea, Cherubini; Carmen, Barba; Umberto, Bivona; Rita, Formisano; Umberto, Sabatini.

In: Functional Neurology, Vol. 25, No. 2, 04.2010, p. 109-114.

Research output: Contribution to journalArticle

Giacomo, Luccichenti ; Elisabetta, Giugni ; Patrice, Péran ; Andrea, Cherubini ; Carmen, Barba ; Umberto, Bivona ; Rita, Formisano ; Umberto, Sabatini. / 3 Tesla is twice as sensitive as 1.5 Tesla magnetic resonance imaging in the assessment of diffuse axonal injury in traumatic brain injury patients. In: Functional Neurology. 2010 ; Vol. 25, No. 2. pp. 109-114.
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