TY - JOUR
T1 - 3 Tesla is twice as sensitive as 1.5 Tesla magnetic resonance imaging in the assessment of diffuse axonal injury in traumatic brain injury patients
AU - Giacomo, Luccichenti
AU - Elisabetta, Giugni
AU - Patrice, Péran
AU - Andrea, Cherubini
AU - Carmen, Barba
AU - Umberto, Bivona
AU - Rita, Formisano
AU - Umberto, Sabatini
PY - 2010/4
Y1 - 2010/4
N2 - Diffuse axonal injury (DAI), associated with deafferentation and functional rearrangement, probably plays a role in the chronic phase of traumatic brain injury (TBI). DAI with a haemorrhagic component can be quantified using magnetic resonance imaging (MRI) thanks to the iron-based susceptibility effect of haemosiderin, which increases with magnetic field strength. The aim of this work was to compare conventional 1.5 Tesla and 3 Tesla MRI in the assessment of DAI in TBI patients. Eighteen TBI patients were submitted, in random order, to a 1.5T and a 3T MRI examination using standard gradient echo sequences. Both scans were always performed on the same day. DAI lesions with a haemorrhagic component were manually segmented and classified by anatomical location. The Wilcoxon and ANOVA tests were used for statistical analysis, significance being set at p
AB - Diffuse axonal injury (DAI), associated with deafferentation and functional rearrangement, probably plays a role in the chronic phase of traumatic brain injury (TBI). DAI with a haemorrhagic component can be quantified using magnetic resonance imaging (MRI) thanks to the iron-based susceptibility effect of haemosiderin, which increases with magnetic field strength. The aim of this work was to compare conventional 1.5 Tesla and 3 Tesla MRI in the assessment of DAI in TBI patients. Eighteen TBI patients were submitted, in random order, to a 1.5T and a 3T MRI examination using standard gradient echo sequences. Both scans were always performed on the same day. DAI lesions with a haemorrhagic component were manually segmented and classified by anatomical location. The Wilcoxon and ANOVA tests were used for statistical analysis, significance being set at p
KW - Diffuse axonal injury
KW - Gradient echo sequences
KW - High-field magnetic resonance
KW - Traumatic brain injury
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M3 - Article
C2 - 20923609
AN - SCOPUS:77957679309
VL - 25
SP - 109
EP - 114
JO - Functional Neurology
JF - Functional Neurology
SN - 0393-5264
IS - 2
ER -