3D MTR measurement: From 1.5 T to 3.0 T

Mara Cercignani, Mark R. Symms, Maria Ron, Gareth J. Barker

Research output: Contribution to journalArticlepeer-review


This study investigates some of the issues involved in magnetization transfer ratio (MTR) acquisition, and in particular aims to determine whether high quality in vivo MTR measurements can be made at 3.0 T. The dependency of the MTR white-to-grey matter contrast to noise ratio (CNR) on MT pulse characteristics at 1.5 T and at 3.0 T was investigated using an established two-pool model for MT. The simulations showed that MT pulse parameters optimizing the CNR can be derived for both field strengths. Both the SNR and the CNR of MTR maps at 3.0 T were increased compared to 1.5 T. Images obtained using a safe in vivo MTR acquisition protocol based on results of simulations at 3.0 T are presented.

Original languageEnglish
Pages (from-to)181-186
Number of pages6
Issue number1
Publication statusPublished - May 15 2006

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology


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