808-nm laser with exogenous chromophores for the treatment of benign oral lesions

O. Marangoni, M. Melato, Leonardo Longo

Research output: Contribution to journalArticlepeer-review


Objective: The aim of this study was to verify the effectiveness and safety of the 808-nm wavelength for use on benign lesions of the oral cavity that are stained with toluidine blue solution. Materials and Methods: The toluidine blue solution according to Mashberg is used in stomatology for the detection of leuko-erythroplasic lesions. In our experience, we have used it to stain even serous cysts, angiomas, and fibromas. We chose a 808-nm wavelength emitted from a power diode laser, because it is well absorbed by the blue color and barely by the healthy mucosa. The non-contact photocoagulation kept the surrounding borders intact when we used the pulsed-emission, 50 ms 7 W, without anesthesia. No sutures were needed. The leukoplasic borders of the lesions were histologically examined before and after the treatment. Results: The vaporized lesions healed completely in about 5-7 days without any kind of treatment, leaving some slight elastic white scars. A mild edema-erythema followed the treatment for 5-7 days. Conclusions: The selective results confirm the effectiveness of this therapeutic procedure on pigmented benign lesions, pre-treated with exogenous chromophores and photocoagulated without bleeding, with a minimum energy 808-nm laser.

Original languageEnglish
Pages (from-to)324-327
Number of pages4
JournalPhotomedicine and Laser Surgery
Issue number3
Publication statusPublished - Jun 2005

ASJC Scopus subject areas

  • Biomedical Engineering
  • Surgery
  • Dermatology
  • Oral Surgery


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