Tomografia cardiaca con 99mTc sestamibi ed ecocardiografia con dobutamina nell'identificazione della disfunzione ventricolare sinistra reversibile nei pazienti con infarto acuto del miocardio

Translated title of the contribution: 99mTc sestamibi cardiac tomography and dobutamine echocardiography in the identification of reversible left ventricular dysfunction in patients with acute myocardial infarction

P. Gisonni, A. Cuocolo, L. Spinelli, W. Acampa, L. Florimonte, E. Nicolai, M. Petretta, A. Sodano

Research output: Contribution to journalArticle

Abstract

Introduction. We investigated the role of technetium-99m (99mTc) sestamibi cardiac imaging and dobutamine echocardiography in detecting myocardial viability early after acute myocardial infarction. Material and methods. Nineteen patients (mean age 52 ± 10 years) underwent coronary angiography, low-dose dobutamine echocardiography and rest 99mTc sestamibi imaging within 10 days of myocardial infarction. All patients were revascularized. Resting echocardiogram was repeated 8 months later to evaluate segmental functional recovery. Results. Sixty-one of 108 akinetic or dyskinetic segments at baseline showed functional recovery after revascularization. Sensitivity in predicting segmental functional recovery was 87% for sestamibi imaging and 66% for dobutamine echocardiography (p <0.001), while specificity and accuracy were comparable. Sestamibi activity was the strongest predictor of segmental functional recovery (p <0.001). Conclusions. Dobutamine echocardiography predicts functional recovery after myocardial infarction. However, sestamibi imaging is useful to identify patients with dysfunctional segments without contractile reserve which may benefit by revascularization.

Original languageItalian
Pages (from-to)265-270
Number of pages6
JournalRadiologia Medica
Volume97
Issue number4
Publication statusPublished - 1999

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Technetium Tc 99m Sestamibi
Dobutamine
Left Ventricular Dysfunction
Echocardiography
Myocardial Infarction
Tomography
Coronary Angiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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Tomografia cardiaca con 99mTc sestamibi ed ecocardiografia con dobutamina nell'identificazione della disfunzione ventricolare sinistra reversibile nei pazienti con infarto acuto del miocardio. / Gisonni, P.; Cuocolo, A.; Spinelli, L.; Acampa, W.; Florimonte, L.; Nicolai, E.; Petretta, M.; Sodano, A.

In: Radiologia Medica, Vol. 97, No. 4, 1999, p. 265-270.

Research output: Contribution to journalArticle

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abstract = "Introduction. We investigated the role of technetium-99m (99mTc) sestamibi cardiac imaging and dobutamine echocardiography in detecting myocardial viability early after acute myocardial infarction. Material and methods. Nineteen patients (mean age 52 ± 10 years) underwent coronary angiography, low-dose dobutamine echocardiography and rest 99mTc sestamibi imaging within 10 days of myocardial infarction. All patients were revascularized. Resting echocardiogram was repeated 8 months later to evaluate segmental functional recovery. Results. Sixty-one of 108 akinetic or dyskinetic segments at baseline showed functional recovery after revascularization. Sensitivity in predicting segmental functional recovery was 87{\%} for sestamibi imaging and 66{\%} for dobutamine echocardiography (p <0.001), while specificity and accuracy were comparable. Sestamibi activity was the strongest predictor of segmental functional recovery (p <0.001). Conclusions. Dobutamine echocardiography predicts functional recovery after myocardial infarction. However, sestamibi imaging is useful to identify patients with dysfunctional segments without contractile reserve which may benefit by revascularization.",
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TY - JOUR

T1 - Tomografia cardiaca con 99mTc sestamibi ed ecocardiografia con dobutamina nell'identificazione della disfunzione ventricolare sinistra reversibile nei pazienti con infarto acuto del miocardio

AU - Gisonni, P.

AU - Cuocolo, A.

AU - Spinelli, L.

AU - Acampa, W.

AU - Florimonte, L.

AU - Nicolai, E.

AU - Petretta, M.

AU - Sodano, A.

PY - 1999

Y1 - 1999

N2 - Introduction. We investigated the role of technetium-99m (99mTc) sestamibi cardiac imaging and dobutamine echocardiography in detecting myocardial viability early after acute myocardial infarction. Material and methods. Nineteen patients (mean age 52 ± 10 years) underwent coronary angiography, low-dose dobutamine echocardiography and rest 99mTc sestamibi imaging within 10 days of myocardial infarction. All patients were revascularized. Resting echocardiogram was repeated 8 months later to evaluate segmental functional recovery. Results. Sixty-one of 108 akinetic or dyskinetic segments at baseline showed functional recovery after revascularization. Sensitivity in predicting segmental functional recovery was 87% for sestamibi imaging and 66% for dobutamine echocardiography (p <0.001), while specificity and accuracy were comparable. Sestamibi activity was the strongest predictor of segmental functional recovery (p <0.001). Conclusions. Dobutamine echocardiography predicts functional recovery after myocardial infarction. However, sestamibi imaging is useful to identify patients with dysfunctional segments without contractile reserve which may benefit by revascularization.

AB - Introduction. We investigated the role of technetium-99m (99mTc) sestamibi cardiac imaging and dobutamine echocardiography in detecting myocardial viability early after acute myocardial infarction. Material and methods. Nineteen patients (mean age 52 ± 10 years) underwent coronary angiography, low-dose dobutamine echocardiography and rest 99mTc sestamibi imaging within 10 days of myocardial infarction. All patients were revascularized. Resting echocardiogram was repeated 8 months later to evaluate segmental functional recovery. Results. Sixty-one of 108 akinetic or dyskinetic segments at baseline showed functional recovery after revascularization. Sensitivity in predicting segmental functional recovery was 87% for sestamibi imaging and 66% for dobutamine echocardiography (p <0.001), while specificity and accuracy were comparable. Sestamibi activity was the strongest predictor of segmental functional recovery (p <0.001). Conclusions. Dobutamine echocardiography predicts functional recovery after myocardial infarction. However, sestamibi imaging is useful to identify patients with dysfunctional segments without contractile reserve which may benefit by revascularization.

KW - Heart, dobutamine echocardiography

KW - Heart, left ventricular dysfunction

KW - Heart, myocardial scintigraphy

KW - Heart, myocardial viability

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