Find Research Outputs — Italian Ministry of Health

2019

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade

Jacquelot, N., Yamazaki, T., Roberti, M. P., Duong, C. P. M., Andrews, M. C., Verlingue, L., Ferrere, G., Becharef, S., Vétizou, M., Daillère, R., Messaoudene, M., Enot, D. P., Stoll, G., Ugel, S., Marigo, I., Foong Ngiow, S., Marabelle, A., Prevost-Blondel, A., Gaudreau, P. O., Gopalakrishnan, V. & 13 others, Eggermont, A. M., Opolon, P., Klein, C., Madonna, G., Ascierto, P. A., Sucker, A., Schadendorf, D., Smyth, M. J., Soria, J. C., Kroemer, G., Bronte, V., Wargo, J. & Zitvogel, L., 2019, In : Cell Research.

Research output: Contribution to journal › Article

Interferon Type I

Regulatory T-Lymphocytes

Nitric Oxide Synthase

Monoclonal Antibodies

Immunotherapy

1 Citation (Scopus)

SVR12 rates higher than 99% after sofosbuvir/ velpatasvir combination in HCV infected patients with F0-F1 fibrosis stage: A real world experience

Mangia, A., Piazzolla, V., Giannelli, A., Visaggi, E., Minerva, N., Palmieri, V., Carraturo, I., Potenza, D., Napoli, N., Lauletta, G., Tagarielli, V., Santoro, R., Piccigallo, E., De Gioia, S., Chimenti, A., Cuccorese, G., Metrangolo, A., Mazzola, M., Agostinacchio, E., Mennea, G. & 4 others, Sabbà, C., Cela, M., Copetti, M. & Losappio, R., May 1 2019, In : PLoS One. 14, 5, e0215783.

Research output: Contribution to journal › Article

Open Access

fibrosis

Fibrosis

Ribavirin

Sensitivity analysis

Tablets

Swallowing safety and efficiency after open partial horizontal laryngectomy: A videofluoroscopic study

Pizzorni, N., Schindler, A., Castellari, M., Fantini, M., Crosetti, E. & Succo, G., Apr 1 2019, In : Cancers. 11, 4, 549.

Research output: Contribution to journal › Article

Open Access

Laryngectomy

Deglutition

Safety

Deglutition Disorders

Tongue

Switching patients in the age of long-acting recombinant products?

Escobar, M., Santagostino, E., Mancuso, M. E., Coppens, M., Balasa, V., Taylor, J. A., Iorio, A. & Negrier, C., Jan 14 2019, In : Expert Review of Hematology. 12, sup1, p. 1-13 13 p.

Research output: Contribution to journal › Article

Open Access

Pharmacokinetics

Hemorrhage

Safety

Factor IX

Expert Testimony

Switch to dolutegravir and unboosted atazanavir in HIV-1 infected patients with undetectable viral load and long exposure to antiretroviral therapy

DAU Study Group, Jun 1 2019, In : AIDS (London, England). 33, 7, p. 1256-1260 5 p.

Research output: Contribution to journal › Article

Viral Load

HIV-1

Reverse Transcriptase Inhibitors

Cardiovascular Diseases

HIV

Symbitron: Symbiotic man-machine interactions in wearable exoskeletons to enhance mobility for paraplegics

van der Kooij, H., van Asseldonk, E., van Oort, G., Sluiter, V., Emmens, A., Witteveen, H., Tagliamonte, N. L., Tamburella, F., Pisotta, I., Masciullo, M., Arquilla, M., Molinari, M., Wu, A., Ijspeert, A., Dzeladini, F. F., Thorsteinsson, F., Arami, A., Burdet, E., Huang, H. Y., Gregoor, W. & 1 others, Meijneke, C., Jan 1 2019, Biosystems and Biorobotics. Springer International Publishing, p. 361-364 4 p. (Biosystems and Biorobotics; vol. 22).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Human computer interaction

Sympathetic and baroreflex alterations in congestive heart failure with preserved, midrange and reduced ejection fraction

Seravalle, G., Quarti-Trevano, F., Dell'Oro, R., Gronda, E., Spaziani, D., Facchetti, R., Cuspidi, C., Mancia, G. & Grassi, G., Feb 2019, In : Journal of Hypertension. 37, 2, p. 443-448 6 p.

Research output: Contribution to journal › Article

Baroreflex

Heart Failure

Norepinephrine

Muscles

Stroke Volume

Sympathetic arousal in children with oppositional defiant disorder and its relation to emotional dysregulation

Tonacci, A., Billeci, L., Calderoni, S., Levantini, V., Masi, G., Milone, A., Pisano, S. & Muratori, P., Oct 1 2019, In : Journal of Affective Disorders. 257, p. 207-213 7 p.

Research output: Contribution to journal › Article

Attention Deficit and Disruptive Behavior Disorders

Child Behavior

Arousal

Checklist

Anger

2 Citations (Scopus)

Symptoms, disease severity and treatment of adults with a new diagnosis of severe aortic stenosis

IMPULSE registry group, Nov 1 2019, In : Heart (British Cardiac Society). 105, 22, p. 1709-1716 8 p.

Research output: Contribution to journal › Article

Aortic Valve Stenosis

Aortic Valve

Therapeutics

Echocardiography

Heart Valve Diseases

3 Citations (Scopus)

Symptom severity and quality of life in the management of vulvovaginal atrophy in postmenopausal women

Panay, N., Palacios, S., Bruyniks, N., Particco, M. & Nappi, R. E., Jun 1 2019, In : Maturitas. 124, p. 55-61 7 p.

Research output: Contribution to journal › Article

Atrophy

Quality of Life

Aging of materials

Therapeutics

Health

Synapsin I controls synaptic maturation of long-range projections in the lateral amygdala in a targeted selective fashion

Lugarà, E., De Fusco, A., Lignani, G., Benfenati, F. & Humeau, Y., May 14 2019, In : Frontiers in Cellular Neuroscience. 13, 220.

Research output: Contribution to journal › Article

Open Access

Synapsins

Amygdala

Interneurons

Neurons

Synapses

Synapsins are expressed at neuronal and non-neuronal locations in Octopus vulgaris

Maiole, F., Tedeschi, G., Candiani, S., Maragliano, L., Benfenati, F. & Zullo, L., Dec 1 2019, In : Scientific Reports. 9, 1, 15430.

Research output: Contribution to journal › Article

Open Access

Synapsins

Octopodiformes

Invertebrates

Sexual Maturation

Mollusca

Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade

Acquarone, E., Argyrousi, E. K., Van Den Berg, M., Gulisano, W., Fà, M., Staniszewski, A., Calcagno, E., Zuccarello, E., D'Adamio, L., Deng, S. X., Puzzo, D., Arancio, O. & Fiorito, J., Jun 27 2019, In : Molecular Neurodegeneration. 14, 1, 26.

Research output: Contribution to journal › Article

Open Access

Nitric Oxide

Up-Regulation

Long-Term Potentiation

Type 5 Cyclic Nucleotide Phosphodiesterases

Neuronal Plasticity

Synaptic vesicle protein 2A tumoral expression predicts levetiracetam adverse events

Romoli, M., Mandarano, M., Romozzi, M., Eusebi, P., Bedetti, C., Nardi Cesarini, E., Verzina, A., Calvello, C., Loreti, E., Sidoni, A., Giovenali, P., Calabresi, P. & Costa, C., Jan 1 2019, In : Journal of Neurology.

Research output: Contribution to journal › Article

etiracetam

Synaptic Vesicles

Proteins

Brain Neoplasms

Glioma

Syncope and autonomic failure in a middle-aged man

Colombo, G., Frattini, E., Ceriani, E., Zilocchi, M., Del Bo, R., Di Fonzo, A. & Solbiati, M., 2019, In : Internal and Emergency Medicine. 14, 2, p. 271-274 4 p.

Research output: Contribution to journal › Article

Syncope in a Working-Age Population: Recurrence Risk and Related Risk Factors

Barbic, F., Dipaola, F., Casazza, G., Borella, M., Minonzio, M., Solbiati, M., Raj, S. R., Sheldon, R., Quinn, J., Costantino, G. & Furlan, R., Jan 29 2019, In : Journal of Clinical Medicine. 8, 2, E150.

Research output: Contribution to journal › Article

Syncope

Recurrence

Population

Anemia

Diabetes Mellitus

Syndrome of inappropriate anti-diuretic hormone secretion in cancer patients: results of the first multicenter Italian study

Berardi, R., Mastroianni, C., Lo Russo, G., Buosi, R., Santini, D., Montanino, A., Carnaghi, C., Tiseo, M., Chiari, R., Camerini, A., Barni, S., De Marino, V., Ferrari, D., Cristofano, A., Doni, L., Freddari, F., Fumagalli, D., Portalone, L., Sarmiento, R., Schinzari, G. & 18 others, Sperandi, F., Tucci, M., Inno, A., Ciuffreda, L., Mariotti, M., Mariani, C., Caramanti, M., Torniai, M., Gallucci, R., Bennati, C., Bordi, P., Buffoni, L., Galeassi, A., Ghidini, M., Grossi, E., Morabito, A., Vincenzi, B. & Arvat, E., Jan 1 2019, In : Therapeutic Advances in Medical Oncology. 11

Research output: Contribution to journal › Article

Open Access

Inappropriate ADH Syndrome

Diuretics

Multicenter Studies

Hyponatremia

Hospitalization

Syndromes of Resistance to Thyroid Hormone Action

Persani, L. & Campi, I., Jan 1 2019, In : Experientia supplementum (2012). 111, p. 55-84 30 p.

Research output: Contribution to journal › Review article

Thyroid Hormone Resistance Syndrome

Thyroid Hormones

Mutation

Thyroid Hormone Receptors alpha

Thyroid Hormone Receptors beta

1 Citation (Scopus)

Synergistic Cytotoxic Effect of Busulfan and the PARP Inhibitor Veliparib in Myeloproliferative Neoplasms

Patel, P. R., Senyuk, V., Rodriguez, N. S., Oh, A. L., Bonetti, E., Mahmud, D., Barosi, G., Mahmud, N. & Rondelli, D., Jan 1 2019, In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journal › Article

Busulfan

Neoplasms

Primary Myelofibrosis

Alkylating Agents

Hematopoietic Stem Cell Transplantation

Synergistic influences of sensory and central stimuli on non-voluntary rhythmic arm movements

Solopova, I. A., Zhvansky, D. S., Selionov, V. A. & Ivanenko, Y., Apr 1 2019, In : Human Movement Science. 64, p. 230-239 10 p.

Research output: Contribution to journal › Article

Arm

Muscles

Central Pattern Generators

Transcranial Magnetic Stimulation

Median Nerve

1 Citation (Scopus)

Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands

Romeo, G., Prezzavento, O., Intagliata, S., Pittalà, V., Modica, M. N., Marrazzo, A., Turnaturi, R., Parenti, C., Chiechio, S., Arena, E., Campisi, A., Sposito, G. & Salerno, L., Jul 15 2019, In : European Journal of Medicinal Chemistry. p. 226-235 10 p.

Research output: Contribution to journal › Article

Benzoxazoles

sigma Receptors

Scaffolds

Assays

Cells

Synthesis and Anti-proliferative Activity of Novel Polysubstitued Indazole Derivatives

Bassou, O., Chicha, H., Allam, A., Monticone, M., Gangemi, R., Maric, I., Viale, M. & Rakib, E. M., Jan 1 2019, In : Journal of Heterocyclic Chemistry. 56, 1, p. 343-348 6 p.

Research output: Contribution to journal › Article

Indazoles

Cells

Derivatives

Amines

Chlorides

2 Citations (Scopus)

Synthesis and biological evaluation of N-biphenyl-nicotinic based moiety compounds: A new class of antimitotic agents for the treatment of Hodgkin Lymphoma

Porcelli, L., Stolfa, D., Stefanachi, A., Di Fonte, R., Garofoli, M., Iacobazzi, R. M., Silvestris, N., Guarini, A., Cellamare, S. & Azzariti, A., Mar 31 2019, In : Cancer Letters. 445, p. 1-10 10 p.

Research output: Contribution to journal › Article

Antimitotic Agents

Hodgkin Disease

Tubulin

Cell Line

Microtubules

Synthetic Blocks for Bone Regeneration: A Systematic Review and Meta-Analysis

Tumedei, M., Savadori, P. & Del Fabbro, M., Aug 28 2019, In : International Journal of Molecular Sciences. 20, 17

Research output: Contribution to journal › Review article

Open Access

osteogenesis

Bone Regeneration

regeneration

Osteogenesis

bones

Synthetic indicator of the impact of colorectal cancer screening programmes on incidence rates

AIRTUM Working Group & Galasso, R., Apr 30 2019, In : Gut.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis: Focus on giant cell arteritis

Monti, S., Águeda, A. F., Luqmani, R. A., Buttgereit, F., Cid, M., Dejaco, C., Mahr, A., Ponte, C., Salvarani, C., Schmidt, W. & Hellmich, B., Sep 1 2019, In : RMD Open. 5, 2, e001003.

Research output: Contribution to journal › Article

Open Access

Giant Cell Arteritis

Vasculitis

Glucocorticoids

Platelet Aggregation Inhibitors

Physiologic Monitoring

Systematic review and analysis of efficacy of recombinant factor IX products for prophylactic treatment of hemophilia B in comparison with rIX-FP

Davis, J., Yan, S., Matsushita, T., Alberio, L., Bassett, P. & Santagostino, E., Jan 1 2019, In : Journal of Medical Economics. 22, 10, p. 1014-1021

Research output: Contribution to journal › Article

Hemophilia B

Factor IX

Half-Life

Joints

Hemorrhage

Systematic Review and Meta-Analysis of the Clinical Evidence on the Use of Autologous Matrix-Induced Chondrogenesis in the Knee

Steinwachs, M. R., Gille, J., Volz, M., Anders, S., Jakob, R., De Giromlamo, L., Volpi, P., Schiavone-Panni, A., Scheffler, S., Reiss, E. & Wittmann, U., Jan 1 2019, (Accepted/In press) In : Cartilage.

Research output: Contribution to journal › Article

Chondrogenesis

Meta-Analysis

Knee

Defects

Pain Measurement

Systematic Review and Meta-Analysis on Neuropsychological Effects of Long-Term Use of Opioids in Patients With Chronic Noncancer Pain

Allegri, N., Mennuni, S., Rulli, E., Vanacore, N., Corli, O., Floriani, I., De Simone, I., Allegri, M., Govoni, S., Vecchi, T., Sandrini, G., Liccione, D. & Biagioli, E., Mar 2019, In : Pain Practice. 19, 3, p. 328-343 16 p.

Research output: Contribution to journal › Article

Chronic Pain

Opioid Analgesics

Meta-Analysis

Anticonvulsants

Antidepressive Agents

Systematic Review and Meta-Analysis on Neuropsychological Effects of Long-Term Use of Opioids in Patients With Chronic Noncancer Pain

Allegri, N., Mennuni, S., Rulli, E., Vanacore, N., Corli, O., Floriani, I., De Simone, I., Allegri, M., Govoni, S., Vecchi, T., Sandrini, G., Liccione, D. & Biagioli, E., Mar 2019, In : Pain Practice. 19, 3, p. 328-343 16 p.

Research output: Contribution to journal › Review article

Chronic Pain

Opioid Analgesics

Meta-Analysis

Anticonvulsants

Antidepressive Agents

2 Citations (Scopus)

Systematic review finds that fever phobia is a worldwide issue among caregivers and healthcare providers

Clericetti, C. M., Milani, G. P., Bianchetti, M. G., Simonetti, G. D., Fossali, E. F., Balestra, A. M., Bozzini, M. A., Agostoni, C. & Lava, S. A. G., Jan 1 2019, In : Acta Paediatrica, International Journal of Paediatrics. 108, 8, p. 1393-1397

Research output: Contribution to journal › Review article

Phobic Disorders

Health Personnel

Caregivers

Fever

National Library of Medicine (U.S.)

Systematic review of ablative therapy for the treatment of renal allograft neoplasms

Favi, E., Raison, N., Ambrogi, F., Delbue, S., Clementi, M. C., Lamperti, L., Perego, M., Bischeri, M. & Ferraresso, M., Sep 1 2019, In : World Journal of Clinical Cases. 7, 17, p. 2487-2504 18 p.

Research output: Contribution to journal › Review article

Open Access

Kidney Neoplasms

Allografts

Neoplasms

Cryosurgery

Electroporation

1 Citation (Scopus)

Systematic Review of adverse events reporting in clinical trials leading to approval of targeted therapy and immunotherapy

Bossi, P., Botta, L., Bironzo, P., Sonetto, C., Musettini, G., Sbrana, A., Di Giannantonio, V., Locati, L. D., Di Maio, M. & Antonuzzo, A., Jul 2019, In : Future Oncology. 15, 21, p. 2543-2553 11 p.

Research output: Contribution to journal › Review article

Immunotherapy

Clinical Trials

Publications

Therapeutics

Pharmaceutical Preparations

2 Citations (Scopus)

Systematic Review on Polyphenol Intake and Health Outcomes: Is there Sufficient Evidence to Define a Health-Promoting Polyphenol-Rich Dietary Pattern?

Del Bo, C., Bernardi, S., Marino, M., Porrini, M., Tucci, M., Guglielmetti, S., Cherubini, A., Carrieri, B., Kirkup, B., Kroon, P., Zamora-Ros, R., Liberona, N. H., Andres-Lacueva, C. & Riso, P., Jun 1 2019, In : Nutrients. 11, 6, 1355.

Research output: Contribution to journal › Article

Open Access

health promotion

systematic review

Polyphenols

eating habits

polyphenols

1 Citation (Scopus)

Systematic review with meta-analysis: Safety and efficacy of local injections of mesenchymal stem cells in perianal fistulas

Ciccocioppo, R., Klersy, C., Leffler, D. A., Rogers, R., Bennett, D. & Corazza, G. R., Jun 1 2019, In : JGH Open. 3, 3, p. 249-260 12 p.

Research output: Contribution to journal › Review article

Open Access

Mesenchymal Stromal Cells

Fistula

Meta-Analysis

Safety

Injections

Systemic activation of Nrf2 pathway in Parkinson's disease

Petrillo, S., Schirinzi, T., Di Lazzaro, G., D'Amico, J., Colona, V. L., Bertini, E., Pierantozzi, M., Mari, L., Mercuri, N. B., Piemonte, F. & Pisani, A., Jan 1 2019, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journal › Article

Parkinson Disease

Synucleins

Leukocytes

NAD(P)H Dehydrogenase (Quinone)

Glutathione Disulfide

1 Citation (Scopus)

Systemic and intraocular factors related to retinal thicknesses variations in patients with Parkinson's disease

Ferro Desideri, L., Barra, F. & Ferrero, S., Apr 1 2019, In : Parkinsonism and Related Disorders. 61, p. 234-235 2 p.

Research output: Contribution to journal › Letter

Ganglia

Parkinson Disease

Dopamine Agents

Optical Coherence Tomography

Neuroprotective Agents

Systemic manifestations of primary Sjögren's syndrome out of the ESSDAI classification: prevalence and clinical relevance in a large international, multi-ethnic cohort of patients

Sjögren Big Data Consortium, May 1 2019, In : Clinical and Experimental Rheumatology. 37, 3, p. 97-106 10 p.

Research output: Contribution to journal › Article

Raynaud Disease

amsonic acid

Cryoglobulins

Minor Salivary Glands

Information Dissemination

T2*-weighted MRI values correlate with motor and cognitive dysfunction in Parkinson's disease

Tambasco, N., Paolini Paoletti, F., Chiappiniello, A., Lisetti, V., Nigro, P., Eusebi, P., Chiarini, P., Romoli, M., Brahimi, E., Simoni, S., Filidei, M., Floridi, P., Tarducci, R., Parnetti, L. & Calabresi, P., Aug 1 2019, In : Neurobiology of Aging. 80, p. 91-98 8 p.

Research output: Contribution to journal › Article

Parkinson Disease

Iron

Substantia Nigra

Brain

Magnetic Resonance Imaging

TAB2 c.1398dup variant leads to haploinsufficiency and impairs extracellular matrix homeostasis

Morlino, S., Carbone, A., Ritelli, M., Fusco, C., Giambra, V., Nardella, G., Notarangelo, A., Panelli, P., Mazzoccoli, G., Zoppi, N., Grammatico, P., Wade, E. M., Colombi, M., Castori, M. & Micale, L., Oct 1 2019, In : Human Mutation. 40, 10, p. 1886-1898 13 p.

Research output: Contribution to journal › Article

Haploinsufficiency

Extracellular Matrix

Homeostasis

Fibroblasts

Biological Phenomena

1 Citation (Scopus)

Tackling the diversity of breast cancer related lymphedema: Perspectives on diagnosis, risk assessment, and clinical management

Michelotti, A., Invernizzi, M., Lopez, G., Lorenzini, D., Nesa, F., De Sire, A. & Fusco, N., Apr 1 2019, In : Breast. 44, p. 15-23 9 p.

Research output: Contribution to journal › Review article

Lymph Nodes

Mastectomy

Therapeutics

Lymph Node Excision

Causality

Tag-based next generation sequencing: A feasible and reliable assay for EGFR T790M mutation detection in circulating tumor DNA of non small cell lung cancer patients

Dono, M., De Luca, G., Lastraioli, S., Anselmi, G., Dal Bello, M. G., Coco, S., Vanni, I., Grossi, F., Vigani, A., Genova, C., Ferrarini, M., Ravetti, J. L. & Zupo, S., Apr 27 2019, In : Molecular Medicine. 25, 1, 15.

Research output: Contribution to journal › Article

Open Access

Non-Small Cell Lung Carcinoma

Mutation

DNA

Neoplasms

Protein-Tyrosine Kinases

Tailored, technological therapy: Physician and therapists point of view on robotic rehabilitation

Morone, G., Iosa, M., De Bartolo, D., Antonucci, G. & Paolucci, S., Jan 1 2019, Biosystems and Biorobotics. Springer International Publishing, p. 261-264 4 p. (Biosystems and Biorobotics; vol. 21).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Patient rehabilitation

Robotics

Robots

Innovation

Recovery

Tailored oral anticoagulant prescription in patients with atrial fibrillation: Use and misuse of clinical risk prediction scores

Proietti, M., Vitolo, M. & Boriani, G., Jan 1 2019, (Accepted/In press) In : European Journal of Preventive Cardiology.

Research output: Contribution to journal › Editorial

Tailor-made hand exoskeletons at the university of florence: From kinematics to mechatronic design

Secciani, N., Bianchi, M., Ridolfi, A., Vannetti, F., Volpe, Y., Governi, L., Bianchini, M. & Allotta, B., Jun 1 2019, In : Machines. 7, 2, 22.

Research output: Contribution to journal › Article

Open Access

Mechatronics

Robotics

Kinematics

Industrial engineering

Rehabilitation

Takotsubo cardiomyopathy associated with Kounis syndrome: A clinical case of the “ATAK complex”

Margonato, D., Abete, R., Di Giovine, G., Delfino, P., Grillo, M., Mazzetti, S., Poggio, D., Rossi, J., Khouri, T. & Mortara, A., Jan 1 2019, In : Journal of Cardiology Cases.

Research output: Contribution to journal › Article

Takotsubo Cardiomyopathy

Anaphylaxis

Kinesis

Gadolinium

Heart Arrest

1 Citation (Scopus)