TY - JOUR
T1 - A 15-year experience of two hundred and twenty five consecutive right hepatectomies
AU - Levi Sandri, Giovanni Battista
AU - Colasanti, Marco
AU - Vennarecci, Giovanni
AU - Santoro, Roberto
AU - Lepiane, Pasquale
AU - Mascianà, Gianluca
AU - de Werra, Edoardo
AU - Meniconi, Roberto Luca
AU - Campanelli, Alessandra
AU - Scotti, Andrea
AU - Burocchi, Mirco
AU - Di Castro, Angelo
AU - D'Offizi, Giampiero
AU - Antonini, Mario
AU - Busi Rizzi, Elisa
AU - Ialongo, Pasquale
AU - Garufi, Carlo
AU - Ettorre, Giuseppe Maria
PY - 2016/5/11
Y1 - 2016/5/11
N2 - Background: In case of liver tumor, surgical resection is the therapeutic gold standard to increase patient survival. Among liver resections, right hepatectomy (RH) is defined as a major hepatectomy. The first aim of this study was to analyze the overall morbidity and mortality of patients undergoing RH, the second aim was to assess changes in both patients characteristic and surgical parameters and mortality rates in a single center institution. Materials: From 2001 to December 2015, 225 RH were performed in our center. We analyzed two time period: 2001-2007 and 2008-2015. Results: Ninety days post operative mortality was observed in 9 cases (4%) for the overall cohort. We observed a difference between the two groups in the use of Pringle Maneuver (p. <. 0,001). This result is consistent in each major surgical indication: HCC (p. =0,001), CLM (p. =0,015) and BT (p. =0,015). The estimated blood losses improved (p. =0,028), particularly for the HCC cases (p. =0,024). No difference was observed in terms of number of transfusions received between the two groups. Reduced length of stay was observed in the second group (p. <. 0,001), more markedly for CLM cases (p. =0,001). Conclusion: To further improve the outcomes of RH, it is important to performed this major hepatectomy in hepatobiliary centers with an overall liver resection experience of at least few hundred cases.
AB - Background: In case of liver tumor, surgical resection is the therapeutic gold standard to increase patient survival. Among liver resections, right hepatectomy (RH) is defined as a major hepatectomy. The first aim of this study was to analyze the overall morbidity and mortality of patients undergoing RH, the second aim was to assess changes in both patients characteristic and surgical parameters and mortality rates in a single center institution. Materials: From 2001 to December 2015, 225 RH were performed in our center. We analyzed two time period: 2001-2007 and 2008-2015. Results: Ninety days post operative mortality was observed in 9 cases (4%) for the overall cohort. We observed a difference between the two groups in the use of Pringle Maneuver (p. <. 0,001). This result is consistent in each major surgical indication: HCC (p. =0,001), CLM (p. =0,015) and BT (p. =0,015). The estimated blood losses improved (p. =0,028), particularly for the HCC cases (p. =0,024). No difference was observed in terms of number of transfusions received between the two groups. Reduced length of stay was observed in the second group (p. <. 0,001), more markedly for CLM cases (p. =0,001). Conclusion: To further improve the outcomes of RH, it is important to performed this major hepatectomy in hepatobiliary centers with an overall liver resection experience of at least few hundred cases.
KW - Colorectal metastases
KW - Hepatocellular carcinoma
KW - Liver surgery
KW - Major liver resection
KW - Right hepatectomy
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U2 - 10.1016/j.dld.2016.09.014
DO - 10.1016/j.dld.2016.09.014
M3 - Article
AN - SCOPUS:84992046923
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
SN - 1590-8658
ER -