A brief appraisal on some aspects of the receptor-receptor interaction

Luigi F. Agnati, Sergi Ferré, Pietro Cortelli, Kjell Fuxe

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Receptor-receptor interaction is being recognized as a key cellular mechanism responsible for the integration of signals between different transmission lines at the membrane level. Receptor-receptor interaction extends the classical concept of integration of depolarization and hyperpolarization effects to the integration of chemical events at membrane level. In the present paper only some hypotheses on the possible mechanistic aspects of the interactions between the membrane receptors will be discussed. Furthermore, possible functional consequences of receptor-receptor interaction will be explored. The limitations of the present experimental approaches to the study of receptor-receptor interaction will also be analysed.

Original languageEnglish
Pages (from-to)139-146
Number of pages8
JournalNeurochemistry International
Volume27
Issue number2
DOIs
Publication statusPublished - 1995

Fingerprint

Membranes

ASJC Scopus subject areas

  • Cell Biology
  • Cellular and Molecular Neuroscience
  • Molecular Biology

Cite this

A brief appraisal on some aspects of the receptor-receptor interaction. / Agnati, Luigi F.; Ferré, Sergi; Cortelli, Pietro; Fuxe, Kjell.

In: Neurochemistry International, Vol. 27, No. 2, 1995, p. 139-146.

Research output: Contribution to journalArticle

Agnati, Luigi F. ; Ferré, Sergi ; Cortelli, Pietro ; Fuxe, Kjell. / A brief appraisal on some aspects of the receptor-receptor interaction. In: Neurochemistry International. 1995 ; Vol. 27, No. 2. pp. 139-146.
@article{98145158253443baa15897d80ed82d94,
title = "A brief appraisal on some aspects of the receptor-receptor interaction",
abstract = "Receptor-receptor interaction is being recognized as a key cellular mechanism responsible for the integration of signals between different transmission lines at the membrane level. Receptor-receptor interaction extends the classical concept of integration of depolarization and hyperpolarization effects to the integration of chemical events at membrane level. In the present paper only some hypotheses on the possible mechanistic aspects of the interactions between the membrane receptors will be discussed. Furthermore, possible functional consequences of receptor-receptor interaction will be explored. The limitations of the present experimental approaches to the study of receptor-receptor interaction will also be analysed.",
author = "Agnati, {Luigi F.} and Sergi Ferr{\'e} and Pietro Cortelli and Kjell Fuxe",
year = "1995",
doi = "10.1016/0197-0186(95)00009-W",
language = "English",
volume = "27",
pages = "139--146",
journal = "Neurochemistry International",
issn = "0197-0186",
publisher = "Elsevier Limited",
number = "2",

}

TY - JOUR

T1 - A brief appraisal on some aspects of the receptor-receptor interaction

AU - Agnati, Luigi F.

AU - Ferré, Sergi

AU - Cortelli, Pietro

AU - Fuxe, Kjell

PY - 1995

Y1 - 1995

N2 - Receptor-receptor interaction is being recognized as a key cellular mechanism responsible for the integration of signals between different transmission lines at the membrane level. Receptor-receptor interaction extends the classical concept of integration of depolarization and hyperpolarization effects to the integration of chemical events at membrane level. In the present paper only some hypotheses on the possible mechanistic aspects of the interactions between the membrane receptors will be discussed. Furthermore, possible functional consequences of receptor-receptor interaction will be explored. The limitations of the present experimental approaches to the study of receptor-receptor interaction will also be analysed.

AB - Receptor-receptor interaction is being recognized as a key cellular mechanism responsible for the integration of signals between different transmission lines at the membrane level. Receptor-receptor interaction extends the classical concept of integration of depolarization and hyperpolarization effects to the integration of chemical events at membrane level. In the present paper only some hypotheses on the possible mechanistic aspects of the interactions between the membrane receptors will be discussed. Furthermore, possible functional consequences of receptor-receptor interaction will be explored. The limitations of the present experimental approaches to the study of receptor-receptor interaction will also be analysed.

UR - http://www.scopus.com/inward/record.url?scp=0029007666&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029007666&partnerID=8YFLogxK

U2 - 10.1016/0197-0186(95)00009-W

DO - 10.1016/0197-0186(95)00009-W

M3 - Article

VL - 27

SP - 139

EP - 146

JO - Neurochemistry International

JF - Neurochemistry International

SN - 0197-0186

IS - 2

ER -