TY - JOUR
T1 - A case-control study of risk factor for renal cell cancer in northern Italy
AU - Talamini, Renato
AU - Barón, Anna E.
AU - Barra, Salvatore
AU - Bidoli, Ettore
AU - La Vecchia, Carlo
AU - Negri, Eva
AU - Serraino, Diego
AU - Franceschi, Silvia
PY - 1990/9
Y1 - 1990/9
N2 - A hospital-based case-control study of renal cell cancer was conducted in northern Italy betwen 1986 and 1989, with 240 cases of renal cell cancer (150 males and 90 females), and 665 controls (445 males and 220 females) chosen on the basis of age, sex, and area of residence. No associations were found between renal cell cancer and: body mass index (BMI); number of cigarettes smoked; age at starting to smoke; years of smoking; consumption of wine, beer, spirits, coffee, decaffeinated coffee; tea; intake of animal protein, fruits, and vegetables; various resproductive factors; hormonal use; sexual habits; sexually transmitted diseases; or selected occupational exposures. The odds ratio (OR) was above unity in smokers (OR=1.34 for ≥15 cigarettes/day), but the trends in risk with dose or duration were not statistically significant. Significant positive associations were found between renal cell cancer and sources of fat intake, especially margarine (OR for highest vs lowest intake = 1.71), and oils (OR=1.89) whereas carrot intake showed a negative association (OR=0.62). Also, a history of nephrolithiasis and multiple episodes of cystitis showed weak positive associations (OR=2.00, 95 percent confidence interval (CI) 1.07-3.73; and OR=1.60, 95 percent CI 0.95-2.70, respectively). Address reprint requests to Dr Talamini. The work was conducted with the contribution of the Italian Association for Cancer Research, Milan, Italy and the CNR (Italian National Research Council) Applied Projects "Oncology" (Contract n. 85.02209.44).
AB - A hospital-based case-control study of renal cell cancer was conducted in northern Italy betwen 1986 and 1989, with 240 cases of renal cell cancer (150 males and 90 females), and 665 controls (445 males and 220 females) chosen on the basis of age, sex, and area of residence. No associations were found between renal cell cancer and: body mass index (BMI); number of cigarettes smoked; age at starting to smoke; years of smoking; consumption of wine, beer, spirits, coffee, decaffeinated coffee; tea; intake of animal protein, fruits, and vegetables; various resproductive factors; hormonal use; sexual habits; sexually transmitted diseases; or selected occupational exposures. The odds ratio (OR) was above unity in smokers (OR=1.34 for ≥15 cigarettes/day), but the trends in risk with dose or duration were not statistically significant. Significant positive associations were found between renal cell cancer and sources of fat intake, especially margarine (OR for highest vs lowest intake = 1.71), and oils (OR=1.89) whereas carrot intake showed a negative association (OR=0.62). Also, a history of nephrolithiasis and multiple episodes of cystitis showed weak positive associations (OR=2.00, 95 percent confidence interval (CI) 1.07-3.73; and OR=1.60, 95 percent CI 0.95-2.70, respectively). Address reprint requests to Dr Talamini. The work was conducted with the contribution of the Italian Association for Cancer Research, Milan, Italy and the CNR (Italian National Research Council) Applied Projects "Oncology" (Contract n. 85.02209.44).
KW - Diet
KW - obesity
KW - occupation
KW - renal cell cancer
KW - smoking
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U2 - 10.1007/BF00053163
DO - 10.1007/BF00053163
M3 - Article
C2 - 2102282
AN - SCOPUS:0025492793
VL - 1
SP - 125
EP - 132
JO - Cancer Causes and Control
JF - Cancer Causes and Control
SN - 0957-5243
IS - 2
ER -