A case-control study on family dysfunction in patients with alopecia areata, psoriasis and atopic dermatitis

Françoise Poot, Enora Antoine, Marion Gravellier, Jennifer Hirtt, Stefania Alfani, Giulia Forchetti, Dennis Linder, Damiano Abeni, Stefano Tabolli, And Francesca Sampogna

Research output: Contribution to journalArticle

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Abstract

Family history can provide important information about a patient's psychological status, and thus their disease risk. A multicentric case-control study on family dysfunction was performed on 59 patients with psoriasis (63.7%), atopic dermatitis (11.9%) or alopecia areata (25.4%), and 47 patients with minor skin problems (controls), all attending a dermatological clinic or a psychodermatological consultation. The mean age of subjects was 47.7 years in the cases and 48.8 years in the controls. Women represented 53% of cases and 62% of controls. Patients and controls frst completed the General Health Questionnaire (GHQ-12) and the Toronto Alexithymia Scale (TAS-20) questionnaire. The overall prevalence of anxiety and/or depression in cases was 43.3% (71.4% in atopic dermatitis). To collect the family history a genogram was built by the interviewer during a semi-structured interview. It can show dysfunction in the family, as it highlights alliances and ruptures, generational repetition of behaviours of dependence or vulnerability, and traumatic events. The mean (± standard deviation) genogram score was 6.7 ± 3.3 in the cases and 3.0 ± 2.4 in the controls (p <0.001). The cases had three times the risk of having moderate family dysfunction compared with controls and 16 times the risk of having a severe family dysfunction. The genogram score was correlated with the severity of the disease as evaluated by the patient. In conclusion, family dysfunction may play an important role in the onset or the exacerbation of psoriasis, alopecia, and atopic dermatitis.

Original languageEnglish
Pages (from-to)415-421
Number of pages7
JournalActa Dermato-Venereologica
Volume91
Issue number4
DOIs
Publication statusPublished - Jun 2011

Fingerprint

Alopecia Areata
Atopic Dermatitis
Psoriasis
Case-Control Studies
genealogy
Interviews
Disease
Affective Symptoms
questionnaire
Alopecia
interview
Rupture
vulnerability
Referral and Consultation
Anxiety
Depression
Psychology
anxiety
Skin
event

Keywords

  • Alopecia areata
  • Atopic dermatitis
  • Dermatology
  • Family dysfunction
  • Genogram
  • Psoriasis
  • Psychology

ASJC Scopus subject areas

  • Dermatology

Cite this

Poot, F., Antoine, E., Gravellier, M., Hirtt, J., Alfani, S., Forchetti, G., ... Sampogna, A. F. (2011). A case-control study on family dysfunction in patients with alopecia areata, psoriasis and atopic dermatitis. Acta Dermato-Venereologica, 91(4), 415-421. https://doi.org/10.2340/00015555-1074

A case-control study on family dysfunction in patients with alopecia areata, psoriasis and atopic dermatitis. / Poot, Françoise; Antoine, Enora; Gravellier, Marion; Hirtt, Jennifer; Alfani, Stefania; Forchetti, Giulia; Linder, Dennis; Abeni, Damiano; Tabolli, Stefano; Sampogna, And Francesca.

In: Acta Dermato-Venereologica, Vol. 91, No. 4, 06.2011, p. 415-421.

Research output: Contribution to journalArticle

Poot, F, Antoine, E, Gravellier, M, Hirtt, J, Alfani, S, Forchetti, G, Linder, D, Abeni, D, Tabolli, S & Sampogna, AF 2011, 'A case-control study on family dysfunction in patients with alopecia areata, psoriasis and atopic dermatitis', Acta Dermato-Venereologica, vol. 91, no. 4, pp. 415-421. https://doi.org/10.2340/00015555-1074
Poot, Françoise ; Antoine, Enora ; Gravellier, Marion ; Hirtt, Jennifer ; Alfani, Stefania ; Forchetti, Giulia ; Linder, Dennis ; Abeni, Damiano ; Tabolli, Stefano ; Sampogna, And Francesca. / A case-control study on family dysfunction in patients with alopecia areata, psoriasis and atopic dermatitis. In: Acta Dermato-Venereologica. 2011 ; Vol. 91, No. 4. pp. 415-421.
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